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TQDPESEARPSALVFDGATDSVGELRLPQRESELLPMANGPKMAGSYFSRRETVCTEQLSAAEHLASEIF TPHRLRYSRRGQRLNARLSAARIGAVTVGYLRYGADVELVNSTALDDYHINVPLTSHADSWCGPATAQAT PTQAAVFLPGRPAGIKWAADCGQLCVKFSRTDLEYELEGLLGRPAVRPLNITHSMDLTADSSRAWLALLS VLYREVSRPESIVQHPMTGRHFEQLVMHGFLHAQPHYQAMALAADQHAAPPPKVLRTALDLIEEHPERSW TTTDLAREVGISARALQESFKRHVGLPPLTYLREVRLIRAHAELAASSESAVTVARVAMKWGFGHLGRFS AEYRRKFGVTPQHTLRAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0534 | - | - | 100% (369) | helix-turn-helix domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0731 | - | 1e-21 | 33.33% (153) | helix-turn-helix domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3905 | - | 2e-20 | 39.32% (117) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2899c | - | 2e-07 | 33.33% (99) | AraC family transcriptional regulator |
| M. marinum M | MMAR_2855 | - | 0.0001 | 27.18% (103) | transcriptional regulatory protein |
| M. avium 104 | MAV_4063 | - | 4e-19 | 32.32% (164) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_2260 | - | 1e-35 | 30.91% (317) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_4270 | - | 8e-53 | 38.14% (312) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2363 | - | 1e-35 | 29.69% (320) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0534|M.gilvum_PYR-GCK MTQDPESEARPSALVFDGATDSVGELRLPQRESELLPMANGPKMAGSYFS
TH_4270|M.thermoresistible__bu -------------------------------------MKDGPLLELGRVR
MSMEG_2260|M.smegmatis_MC2_155 -----------------MSRLTRLGFIDIRRTSDPVRRKVRSRGVPPALA
Mvan_2363|M.vanbaalenii_PYR-1 --------------------------------------------MPPALT
MAB_2899c|M.abscessus_ATCC_199 ------MRSARGPHSGEPGRSGEPHSGRLGRSGEPHSGRLGRSGEPHSGR
MMAR_2855|M.marinum_M --------------------------------------------------
MAV_4063|M.avium_104 --------------MGLTTMTVRDDGAPVGAPAEAARSDYGPVDPVLAVN
Mflv_0534|M.gilvum_PYR-GCK RRETVCTEQLSAAEHLASEIFTPHRLRYSRRGQR-LNARLSAARIGAVTV
TH_4270|M.thermoresistible__bu DR-----DQIRAA---VADIFCPHGLD-VRKGSG-LDASVRAQAAGSIKL
MSMEG_2260|M.smegmatis_MC2_155 DHEIFYTEDVREAARLVGRTLSPLTLTVDAADAGGFAATMHGVRLRNVSL
Mvan_2363|M.vanbaalenii_PYR-1 EHEIFYTEDISKATRLIGRALSPLTLTVDPADADGFAATMHGIRLRNVSM
MAB_2899c|M.abscessus_ATCC_199 LGRSGEPHSVVVLALPGTIGFDLATAVEVFR-RVYLADGSRPYLVRVCGT
MMAR_2855|M.marinum_M -----MARKVVIVGFPGVQPLDVVGPFEVFAGASLLSEGGYDVALASIDE
MAV_4063|M.avium_104 GERRARPVAVEYKQFRGADAQSARRFFATAYDPGWRIAGVTNHCVVSHRR
:
Mflv_0534|M.gilvum_PYR-GCK GYLRYGADVELVNST---ALDDYHIN-VPLTSHADSWCGPATAQATPTQA
TH_4270|M.thermoresistible__bu VWVTYGAPVRIDVPP---PSEPFHLVQIPLQGYLSVTSGDEEVVSDSALA
MSMEG_2260|M.smegmatis_MC2_155 LYLDLHVAATLDIP----ESGRYFAVHMPLNGSATVTHPAAEFDAGTTRS
Mvan_2363|M.vanbaalenii_PYR-1 LYLDLHVPASIDIP----ESGRYYAVHMPMNGVAMVHHPSSTFQASTLRS
MAB_2899c|M.abscessus_ATCC_199 EPVVSAGPFGIATDLGLEAVSEAETIVVPARDNPTAPLP-EGVLDALRGA
MMAR_2855|M.marinum_M RPVATGIGLEFMTTRLPDPSAPVDTVVLPGGGGVDAARDNVALMDWVKAA
MAV_4063|M.avium_104 SDTGSMTVDEVAIQGRMTLEIPAGDTVVVIQPRAGALNVAGGPLATPDFP
. : .
Mflv_0534|M.gilvum_PYR-GCK AVFLPGRPAGIKWAADCGQLCVKFSRTDLEYELEGLLGRPAVRPLNITHS
TH_4270|M.thermoresistible__bu SMPDPRLPCTMRWEAHCSEVIVRIDDDVLHRHLESLLGHPVKAPLHFSLG
MSMEG_2260|M.smegmatis_MC2_155 LVTSPGDPVRMSFAHDSPQMLVRIEEEAMNAHLTRLLGRNLVGPLKFEPE
Mvan_2363|M.vanbaalenii_PYR-1 LVSSPGVPLRIDLGVDTPQLLIRIEQQAMTAHVTRLIGRNLARPLVFEPE
MAB_2899c|M.abscessus_ATCC_199 YERGTRIASICAGAFTLAEAGILDGKRATTHWLAADLFRERYPAVHLDAD
MMAR_2855|M.marinum_M AGTARRVVTVCTGTFLAAEAGLLDGCRATTHWAFADRLAREFPAVDVDPD
MAV_4063|M.avium_104 LLVAHGMACVLHCHG--ARFDVVTIAAEVLQKVAAEWHTALSQQTQFLNW
. : .
Mflv_0534|M.gilvum_PYR-GCK MDLTADSSRAWLALLSVLYREVSRPESIVQHPMTGRHFEQLVMHGFLHAQ
TH_4270|M.thermoresistible__bu MPLDSGPGSSWRAAIDMMITELDRDGGLLKFPLVSAQLESLILTGLLTAQ
MSMEG_2260|M.smegmatis_MC2_155 FDLTTEAATRWHAAVQLIHTEVYHAGSLVQRGCAIGPVEELAMSSLLYLQ
Mvan_2363|M.vanbaalenii_PYR-1 FDLATEAAMRWNAAVQLVHTEVYHAGSLIQKGRAIGPVEELVMSSLLHLQ
MAB_2899c|M.abscessus_ATCC_199 VLYVDEG-QVLTSAGAAAGLDLCLHIVARDHGAAVAAEAARVAVAPLHR-
MMAR_2855|M.marinum_M PIFIRSSPKVWTAAGVTAGIDLALALVEGDHGTEIAQTVARWLVLYLRR-
MAV_4063|M.avium_104 RPRSRAAVRAWHRALDYAMLTLASP-DTARQPLIAAGMAGLLAGALLECY
: *
Mflv_0534|M.gilvum_PYR-GCK PHYQAMALAADQHAAPPPKVLRTALDLIEEHPERSWTTTDLAREVGISAR
TH_4270|M.thermoresistible__bu PHNYTTALLADSGPAPP-RAIRRALDYIESESDRAITTARLAAHVGISAR
MSMEG_2260|M.smegmatis_MC2_155 PSTYYSDITRPTPATPRRAVIQQAVDYIEDHLAEKITMESLAEALHMSVR
Mvan_2363|M.vanbaalenii_PYR-1 PSNYHADITQPSPPDPRRTVIQQAMDFIDDHLAERITMDSLAAAVHMSVR
MAB_2899c|M.abscessus_ATCC_199 DGGQAQYVIRN--RRRAEVSLGEILAWIEHNAHRELSLEDLATEASTSVR
MMAR_2855|M.marinum_M PGGQTQFAAPVWMPRAKRPSIRDVQEAIEAQPGGPHSIEELAHRAAMSPR
MAV_4063|M.avium_104 PSNLTE--QDPVSDLALPETLKEAVSFIHRHAAEDIGINDVAAAVHLTPR
: *. . :* : *
Mflv_0534|M.gilvum_PYR-GCK ALQESFKRHVGLPPLTYLREVRLIRAHAELAASS-ESAVTVARVAMKWGF
TH_4270|M.thermoresistible__bu ALQRGFQEHVGCSPMDYLRDVRLRRARDLLSEADPSAEVTVTEVALECGF
MSMEG_2260|M.smegmatis_MC2_155 SIQQGFRTELGMSPTTFIRERRLERVREELTDAIPSDGVTVTAVAERWGF
Mvan_2363|M.vanbaalenii_PYR-1 SIQQGFRSELGMSPMAFVRERRLERVHEELADAIPSDGVTVTAVAERWGF
MAB_2899c|M.abscessus_ATCC_199 SLNRRFRAETGQTPMQWLTGVRVRHAQQLLERSA----DSVEWIGREVGF
MMAR_2855|M.marinum_M HFTRVFTGEVGEAPRQYVERVRTEAARRQLEETE----DTVVAIAARCGF
MAV_4063|M.avium_104 AVQYLFRRQLDTTPTEYMRRVRLSRAHQELVAAT-TASSTVTEIAQRWGF
. * . . .* :: * .: * : :* :. . **
Mflv_0534|M.gilvum_PYR-GCK GHLGRFSAEYRRKFGVTPQHTLRAA-----
TH_4270|M.thermoresistible__bu MHLGRFSVEYRRRFGESPSETLRR------
MSMEG_2260|M.smegmatis_MC2_155 HHLGSFAVEYRKRWGETPSETLRR------
Mvan_2363|M.vanbaalenii_PYR-1 HHLGSFAVEYRKRWGEAPSETLRR------
MAB_2899c|M.abscessus_ATCC_199 GSPANFREQFRRLTGVSPLAYRNTFRAQSA
MMAR_2855|M.marinum_M GTAETMRRNFIRRVGISPDQYRKAFA----
MAV_4063|M.avium_104 AHTGRFAVLYRQTYGQSPHTTLRQQTAV--
: : : * :* .