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VTAARLSTAGLCVDLGGRRIVEDVSMDVPAGRVVGIVGPNGCGKSTLLRTLGGILRPASGVVSIDGTDIA TLGARQLARTVAAVLQDSAGDFDLRVRDVVLMGRSPYKRMFEGDNASDIRIVGDSLALVDAAHLEDRPFP LLSGGERRRVLVARALAQQPHLLLMDEPTNHLDVRHTFDVLALPATLGVTAVIALHDLNLAAQYCDVIHV LRNGRQVAAGSPADVLTADLLGDVWEVRATVQPHPDTGRPHIYFDPRRRVTEESRSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3884 | - | - | 100% (267) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_1455 | - | 6e-30 | 38.92% (203) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_2856 | - | 2e-27 | 35.29% (255) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 3e-25 | 36.32% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 3e-25 | 36.32% (212) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01892 | - | 1e-25 | 36.05% (233) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_0548c | - | 1e-61 | 47.79% (249) | putative iron compound ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 1e-25 | 33.03% (218) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_4504 | - | 2e-25 | 36.68% (229) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6062 | - | 2e-61 | 52.68% (224) | Fe uptake system permease |
| M. thermoresistible (build 8) | TH_3040 | - | 1e-62 | 51.68% (238) | PUTATIVE putative ABC transporter, ATP-binding protein |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-25 | 36.71% (237) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_5319 | - | 1e-27 | 36.82% (201) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 -MT------YAIVVADATKRYG----DFVALDHVDFVVPTGSLTALLGPS
Rv2397c|M.tuberculosis_H37Rv -MT------YAIVVADATKRYG----DFVALDHVDFVVPTGSLTALLGPS
MUL_3658|M.ulcerans_Agy99 -MTGPGTGGHAIVVRDAFKQYG----DFVALDHVDFVVPAGSLTALLGPS
Mflv_3884|M.gilvum_PYR-GCK -MTAARLSTAGLCVDLGGRR---------IVEDVSMDVPAGRVVGIVGPN
MAB_0548c|M.abscessus_ATCC_199 ----MDVTFRNVSVSIAGAQ---------IISDIHLNVAAGGFVGIVGPN
MSMEG_6062|M.smegmatis_MC2_155 --MTAEVRLHRISVVMSTMRRNR-----PVVDGVSLRVAPGEMVAVVGPN
TH_3040|M.thermoresistible__bu -MTDVRDATATAQTAVCADRVCWTVRGTLIVDGVSLDVTPGSTVGLLGPN
MMAR_0060|M.marinum_M -MTRQDAGRQPVCLAARSIHQTLG--GSVVLRGVDLEVPAGTTAAVIGPS
MLBr_01892|M.leprae_Br4923 MPMGVAIEVKGLTKSFGSSR---------IWEDVTLDIPAGEVSVLLGPS
MAV_4504|M.avium_104 --MGVAIEVNGLTKSFGSSR---------IWEDVTLEIPAGEVSVLLGPS
Mvan_5319|M.vanbaalenii_PYR-1 -MSGPESVEAAPALTFDDVSVDRG--GRTIWSESTFRVDAGSFVAIIGPN
: : .* ::**.
Mb2419c|M.bovis_AF2122/97 GSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQ-----RRGIGFVFQH
Rv2397c|M.tuberculosis_H37Rv GSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQ-----RRGIGFVFQH
MUL_3658|M.ulcerans_Agy99 GSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQ-----RRGIGFVFQH
Mflv_3884|M.gilvum_PYR-GCK GCGKSTLLRTLGGILRPASGVVSIDGTDIATLGARQL---ARTVAAVLQD
MAB_0548c|M.abscessus_ATCC_199 GSGKSTTLRCLYRALTPASGDVAVNGVSVRAISMREN---ARQVAALTQD
MSMEG_6062|M.smegmatis_MC2_155 GAGKTTLLRTIYRAQRPTAGNVLIDGADLWKLPRKRA---AQRVAAVLQE
TH_3040|M.thermoresistible__bu GSGKSTLLRMLAGIRRPSSGVIRLHDQDVTTLARRQV---ARRVAVVEQE
MMAR_0060|M.marinum_M GSGKSTLLRTLNRLHEPDSGDILLDGRSVLRDNPNDL---RQRIGMVFQH
MLBr_01892|M.leprae_Br4923 GTGKSVFLKSLIGLLRPERGSILIDGTDIIECSAKELYEIRTLFGVLFQD
MAV_4504|M.avium_104 GTGKSVFLKSLIGLLRPERGSVVIDGTDILQCSAKELYEIRTLFGVMFQD
Mvan_5319|M.vanbaalenii_PYR-1 GSGKTTLLQVILGLLPPSSGTVRVYGRQPGAANDEIG------YVPQNYD
* **:. *: : * * : : . . . .
Mb2419c|M.bovis_AF2122/97 YAAFKHLTVRDNVAFGLKIRKRPKAEIKAK----VDNLLQVVGLSGFQSR
Rv2397c|M.tuberculosis_H37Rv YAAFKHLTVRDNVAFGLKIRKRPKAEIKAK----VDNLLQVVGLSGFQSR
MUL_3658|M.ulcerans_Agy99 YAAFKHLTVRDNVAYGLKIRKRPKAEIRDK----VDNLLEVVGLSGFHGR
Mflv_3884|M.gilvum_PYR-GCK SAGDFDLRVRDVVLMGRSPYKRMFEGDNASDIRIVGDSLALVDAAHLEDR
MAB_0548c|M.abscessus_ATCC_199 MSLDFDFTAAEVIATGRLPHGASLRGTSQLDRQICARATETADVTALSGR
MSMEG_6062|M.smegmatis_MC2_155 MTTDFELTVYDIVAMGRTPYKRSFESDNATDREIIASALAALDIADLAHA
TH_3040|M.thermoresistible__bu SGTDSDPRVRDVIALGRIPHRRPWAALSDRDLRIIERAAAATDVADRLDQ
MMAR_0060|M.marinum_M FNLFPHRNVVDNVTLAP---RKLRGLSNEEARMLALDQLDRVGLKHKANA
MLBr_01892|M.leprae_Br4923 GALFGSMNLYDNTAFPLREHTKKKESEIRD---IVMEKLQLVGLGGDEKK
MAV_4504|M.avium_104 GALFGSMNLFDNAAFPLREHTKKKESEIRD---IVMEKLELVGLGGDEKK
Mvan_5319|M.vanbaalenii_PYR-1 ANANEAIRASDAVLLGLTGRRWGFGRTSTADRRRVDEALGWVDALDIADR
: .
Mb2419c|M.bovis_AF2122/97 YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
Rv2397c|M.tuberculosis_H37Rv YPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRL
MUL_3658|M.ulcerans_Agy99 YPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRL
Mflv_3884|M.gilvum_PYR-GCK PFPLLSGGERRRVLVARALAQQPHLLLMDEPTNHLDVRHTFDVLALPA--
MAB_0548c|M.abscessus_ATCC_199 TFGSLSGGERQRVLIARALAQQPHVLVLDEPTNHLDVRHQYSILNSAR--
MSMEG_6062|M.smegmatis_MC2_155 PFGRLSGGQKQRVLIARSLAQHTDVIVLDEPTNHLDLRHQHDTLRLLR--
TH_3040|M.thermoresistible__bu HYATLSGGERQRVQLSRAFAQEPEVLLLDEPTNHLDVRHQLDLMRMVR--
MMAR_0060|M.marinum_M RPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKGILALIADL
MLBr_01892|M.leprae_Br4923 FPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDI
MAV_4504|M.avium_104 FPGEISGGMRKRASLARALVMDPQIILCDEPDSGLDPVRTAYLSQLILDI
Mvan_5319|M.vanbaalenii_PYR-1 RLSDLSGGQRQRIALAGALVARPRMLILDEPLASLDLRNQHEIVAVLARL
:*** ::* :: ::. . ::. **. **
Mb2419c|M.bovis_AF2122/97 HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAP-ANA
Rv2397c|M.tuberculosis_H37Rv HDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAP-ANA
MUL_3658|M.ulcerans_Agy99 HDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAP-TNA
Mflv_3884|M.gilvum_PYR-GCK --TLGVTAVIALHDLNLAAQYCDVIHVLRNGRQVAAGSPADVLTAD-LLG
MAB_0548c|M.abscessus_ATCC_199 --ALGITVIAALHDLNLAAQYCDTIHVMADGNVVLSGSPHEVLTAE-SVG
MSMEG_6062|M.smegmatis_MC2_155 --ATGSTVIAALHDLNLAAAYCDRICVLDRGQVVAVGAPREVLTVE-LLA
TH_3040|M.thermoresistible__bu --DAELTSVIAMHDLNLAAAFCDALLVLAHGRVVAAGPPAGVLTAE-LVE
MMAR_0060|M.marinum_M G-ADGMTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGPPEQLFEAA-RTE
MLBr_01892|M.leprae_Br4923 NAQIDATILIVTHNVNIARTVPDNMGMLFRKHLVMFGPREVLLTSDEPVV
MAV_4504|M.avium_104 NAQIDATVLIVTHNINIARTVPDNMGMLFRRKLVMFGPREVLLTSDEPVV
Mvan_5319|M.vanbaalenii_PYR-1 KRDLGVTVLVVAHDLNPLLTVLDSAIYLLDGHAHHAALDR--VVDSQLLT
* : . *: * : .
Mb2419c|M.bovis_AF2122/97 FVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVD
Rv2397c|M.tuberculosis_H37Rv FVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVD
MUL_3658|M.ulcerans_Agy99 FVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGESTGVTRAVVD
Mflv_3884|M.gilvum_PYR-GCK DVWEVRATVQPHPDTGRPHIYFDPRRRVTEESRSG---------------
MAB_0548c|M.abscessus_ATCC_199 RWFGIDCHVITHPRSGVPQVIFYAEPERQEKQ------------------
MSMEG_6062|M.smegmatis_MC2_155 EVYGVDATIG--DTAGVPQITVVPGQAAPR--------------------
TH_3040|M.thermoresistible__bu RVYGVRARIG-HDDTGLYVRFLG---------------------------
MMAR_0060|M.marinum_M RLQRFLAQVL----------------------------------------
MLBr_01892|M.leprae_Br4923 RQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGGAEEVEGVPPQIT
MAV_4504|M.avium_104 KQFLNGRRIGPIGMSEEKDEATMAEEQAALEAGQHAGGVEEIEGVPPQIV
Mvan_5319|M.vanbaalenii_PYR-1 HMYGTRIQVAHTLQGELYMRSGG---------------------------
:
Mb2419c|M.bovis_AF2122/97 RVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVP
Rv2397c|M.tuberculosis_H37Rv RVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVP
MUL_3658|M.ulcerans_Agy99 RIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTVYVRATRVP
Mflv_3884|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0548c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6062|M.smegmatis_MC2_155 --------------------------------------------------
TH_3040|M.thermoresistible__bu --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MLBr_01892|M.leprae_Br4923 VTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLEGAHNYQAHEFGD
MAV_4504|M.avium_104 ASPGMPERKAVARRQARVREILHTLPQKAQAAILDDLEGTHKYRAHEVGD
Mvan_5319|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 PIAGGVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv PIAGGVSGVDDAGVERVKVTST------
MUL_3658|M.ulcerans_Agy99 PIAGAAPAVPDDGAGSTPRAAQIGVGGQ
Mflv_3884|M.gilvum_PYR-GCK ----------------------------
MAB_0548c|M.abscessus_ATCC_199 ----------------------------
MSMEG_6062|M.smegmatis_MC2_155 ----------------------------
TH_3040|M.thermoresistible__bu ----------------------------
MMAR_0060|M.marinum_M ----------------------------
MLBr_01892|M.leprae_Br4923 ----------------------------
MAV_4504|M.avium_104 ----------------------------
Mvan_5319|M.vanbaalenii_PYR-1 ----------------------------