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MSATQVRIETIIDAVDVACRAPSLHNSQPWRWVATDHGVDLYADPDRMIRAADSTGREALISCGAVLDHF RVAMAAAGWSITVERLPEPSDPRHIASIRFAAATEVTAEQKRRADAILVRRTDRLPLSAPRDWDVPGETG AAGAEPDNPVRVHTVPGHKRDMLVEASQLAEVLRLYDSDYHSELFWWTADFVATEGIPRSALVSAAEGDR VGIGRTFPVTTQPERRGELESDDAAIVVLSTEDDSRESVLRCGEALSAFLLDATMTGLATCTVTHITEVP AGRDVVASVLATTSIPQVLVRVGAAPALDAIPAPTPRRPVHDVLEIRRGATC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3845 | - | - | 100% (332) | hypothetical protein Mflv_3845 |
| M. gilvum PYR-GCK | Mflv_4994 | - | 5e-89 | 52.45% (326) | hypothetical protein Mflv_4994 |
| M. gilvum PYR-GCK | Mflv_3848 | - | 2e-44 | 37.88% (330) | hypothetical protein Mflv_3848 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2058 | - | 1e-101 | 56.27% (327) | hypothetical protein Mb2058 |
| M. tuberculosis H37Rv | Rv2032 | acg | 1e-102 | 56.57% (327) | hypothetical protein Rv2032 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3903 | - | 1e-89 | 50.15% (331) | hypothetical protein MAB_3903 |
| M. marinum M | MMAR_3487 | - | 3e-89 | 52.74% (328) | hypothetical protein MMAR_3487 |
| M. avium 104 | MAV_2505 | - | 1e-86 | 51.25% (320) | hypothetical protein MAV_2505 |
| M. smegmatis MC2 155 | MSMEG_5246 | - | 3e-93 | 51.38% (327) | hypothetical protein MSMEG_5246 |
| M. thermoresistible (build 8) | TH_3061 | - | 6e-85 | 51.04% (337) | PUTATIVE 3-ketosteroid-delta4 |
| M. ulcerans Agy99 | MUL_2417 | - | 5e-83 | 48.49% (332) | hypothetical protein MUL_2417 |
| M. vanbaalenii PYR-1 | Mvan_2550 | - | 1e-127 | 65.36% (332) | hypothetical protein Mvan_2550 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3903|M.abscessus_ATCC_1997 -MPKTMVHIDVIQTAIQLACRAPSLHNTQPWRWIVDLGASAG----DLHL
MUL_2417|M.ulcerans_Agy99 ------MDMEVLKTAVLLACRAPSVHNSQPWRWVADRDRDSGSEVVAVHL
Mb2058|M.bovis_AF2122/97 -MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDH--------TVAL
Rv2032|M.tuberculosis_H37Rv -MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDH--------TVAL
MMAR_3487|M.marinum_M -MTETMVDTEVIARAVELASRAPSLHNSQPWRWVAASG--------AVDL
MAV_2505|M.avium_104 MMMQMTADTEVITAAIELACHAPSLHNSQPWRWVAGST--------GVDL
MSMEG_5246|M.smegmatis_MC2_155 -MSDTRLDVATLANAVQLAARAPSLHNTQPWRLIAEDG--------ELKL
Mflv_3845|M.gilvum_PYR-GCK -MSATQVRIETIIDAVDVACRAPSLHNSQPWRWVATDH--------GVDL
Mvan_2550|M.vanbaalenii_PYR-1 -MPATRIRIEAIVDALQLACRAPSLHNSQPWRWVVVDH--------RLDL
TH_3061|M.thermoresistible__bu -MHDHLVELDVIRGAVQLACRAPSLHNSQPWRWVLDRW--------GLRL
.: *: :*.:***:**:**** : : *
MAB_3903|M.abscessus_ATCC_1997 YLDRTRCVTRTDGAGREAIISCGAALDHFRVAMASAGWMTRIERIPDPDN
MUL_2417|M.ulcerans_Agy99 FADRGRTVPATDHSGRETLISCGAVLDHLGVAMTAAGWQPSITRFPTPDD
Mb2058|M.bovis_AF2122/97 FLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPND
Rv2032|M.tuberculosis_H37Rv FLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPND
MMAR_3487|M.marinum_M FLDPHRMVTSADDSGREAVISCGALLDHFQVAMAAAGWDSNVDLFPNPNN
MAV_2505|M.avium_104 FVDPRRTVKSADKSGREAIISCGAALDHFRVAMAAAGWSSNVAQFPNPNN
MSMEG_5246|M.smegmatis_MC2_155 FLDPSRVVRSTDRSSREAVMSCGVLLDHLRVALAAAGWDTEVQRFPNPND
Mflv_3845|M.gilvum_PYR-GCK YADPDRMIRAADSTGREALISCGAVLDHFRVAMAAAGWSITVERLPEPSD
Mvan_2550|M.vanbaalenii_PYR-1 YVDPARVIRSADATGRQALLSCGAALDHFRVAMTAAGWNTSVRRFPDSAD
TH_3061|M.thermoresistible__bu YLDRGRIIRATDRSGREAIISCGAVLDHLRVAMLAAGWVSHIERFPNPDD
: * * : :* :.*::::.**. ***: **: :** : :* . :
MAB_3903|M.abscessus_ATCC_1997 PDHLAAITFS--------PRTVVVVGDRRRADAILQRRTDRLPFETPPNW
MUL_2417|M.ulcerans_Agy99 PNHLATVDFR--------PIEEVTETELKRAESILQRRTDRLAFDRRRYW
Mb2058|M.bovis_AF2122/97 PLHLASIDFS--------PADFVTEGHRLRADAILLRRTDRLPFAEPPDW
Rv2032|M.tuberculosis_H37Rv PLHLASIDFS--------PADFVTEGHRLRADAILLRRTDRLPFAEPPDW
MMAR_3487|M.marinum_M PDHLASIDFA--------AIDDIAQARRERAEAISRRRTDRRPFRAPGDW
MAV_2505|M.avium_104 LDHLASIDVV--------PTEYVARARRDLADAILRRRTNRLPFRAPKHW
MSMEG_5246|M.smegmatis_MC2_155 RDHLATLSFR--------PLQFVTEGHRKRADAILARRTDRLPMSAYVDW
Mflv_3845|M.gilvum_PYR-GCK PRHIASIRFA--------AATEVTAEQKRRADAILVRRTDRLPLSAPRDW
Mvan_2550|M.vanbaalenii_PYR-1 PHHLATIEFA--------AAGEVSYEQKRRADAILLRHSDRLPLAAPPDW
TH_3061|M.thermoresistible__bu PDHLASVRFSRLARLGDRSADEFLAAYRRRADVILLRHTDRRPFGAPPDP
*:*:: . . . *: * *:::* .:
MAB_3903|M.abscessus_ATCC_1997 SQFARMLNTVIAD------RAVLLDVIDDVMRPKLADASALSDALRIYDS
MUL_2417|M.ulcerans_Agy99 DLFEGVLRNTIDN------DIAMLDVLTDEQRPQLVQASHLSAALRRDDL
Mb2058|M.bovis_AF2122/97 DLVESQLRTTVTA------DTVRIDVIADDMRPELAAASKLTESLRLYDS
Rv2032|M.tuberculosis_H37Rv DLVESQLRTTVTA------DTVRIDVIADDMRPELAAASKLTESLRLYDS
MMAR_3487|M.marinum_M ESFEPVLRSSVDT------ETVTLAVLAEDARPRLAEASRLTEALRRYDD
MAV_2505|M.avium_104 SALEPVLRDVGRD------HSVALDVLGPDARPGLVEAARLTEALRRYDD
MSMEG_5246|M.smegmatis_MC2_155 DAFETLLRARLGD------GPVHMDTLGEDVREEVAEAAALTESLRLYDA
Mflv_3845|M.gilvum_PYR-GCK DVPGETGAAGAEP-----DNPVRVHTVPGHKRDMLVEASQLAEVLRLYDS
Mvan_2550|M.vanbaalenii_PYR-1 ERLTDTLTSAAG------RGPAQLHVVAEDLRSPLAEVSRLAEAMRLYDA
TH_3061|M.thermoresistible__bu VGVHQLLAAAAADTADTADTEVHLDVIAPEDRPRLVEASRIAESQRAADT
. : .: * :. .: :: * *
MAB_3903|M.abscessus_ATCC_1997 AYQTELDWWTAPFTLEDGVPRSALVSAADSDRVDIGRTFPVVAERASRPG
MUL_2417|M.ulcerans_Agy99 SYHAELDWWTSPFVLTDGVPPLALASDTERQRVDLSRDFPVRSHQDRRPE
Mb2058|M.bovis_AF2122/97 SYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPE
Rv2032|M.tuberculosis_H37Rv SYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPE
MMAR_3487|M.marinum_M AYHHELAWWTAPSRESEGIPQSALASGTAAREVAVNRSFPVDWRSESSSA
MAV_2505|M.avium_104 DYHHELDWWTSPSRKFDGIPESALVSEADDRRVDVNRRFPVDPLDERSSA
MSMEG_5246|M.smegmatis_MC2_155 AYHSELAWWTTPFATEDGIPQTALISAEESERVAVSRDFPVAPHSSRRPA
Mflv_3845|M.gilvum_PYR-GCK DYHSELFWWTADFVATEGIPRSALVSAAEGDRVGIGRTFPVTTQPERRGE
Mvan_2550|M.vanbaalenii_PYR-1 RYHAELHWWTASFAEREGIPRSALITATESERVDIGRSFPVTASPERRGH
TH_3061|M.thermoresistible__bu PYFLELSWWTVGYDLTEGIPHGVLESAEP-QRVDVGRVFVAGSGQHRPDP
* ** *** :*:* * : .* ..* * .
MAB_3903|M.abscessus_ATCC_1997 LQ--EDQAKVLALSTARDTPKNLLRCGELLSEVLLEATLAGMATCTITHM
MUL_2417|M.ulcerans_Agy99 IT--SDWSKILVLSTPGDTRADVLRCGEVLSSVLLECTMAGMATCTLTHL
Mb2058|M.bovis_AF2122/97 FG--HDRSKVLVLSTYDNERASLLRCGEMLSAVLLDATMAGLATCTLTHI
Rv2032|M.tuberculosis_H37Rv FG--HDRSKVLVLSTYDNERASLLRCGEMLSAVLLDATMAGLATCTLTHI
MMAR_3487|M.marinum_M GR--HDHATIVVLSTPGDSRADALNCGAALSAVLLECTLAGLATCPVTHL
MAV_2505|M.avium_104 GS--YDDAKILVLSTPEDTRADALRVGQVLSRILLECTAAGLATCPVTHV
MSMEG_5246|M.smegmatis_MC2_155 LN--NDAATIVVLSTDGYSREDALDAGEGLSKVLLECTMSGLATCPVTHV
Mflv_3845|M.gilvum_PYR-GCK LE--SDDAAIVVLSTEDDSRESVLRCGEALSAFLLDATMTGLATCTVTHI
Mvan_2550|M.vanbaalenii_PYR-1 LD--EDRAGVLVLSTADDSRESVLRCGEALSAVLLDATMAGMSTCTVTHV
TH_3061|M.thermoresistible__bu SDNPEDHSMIVVLSTNEDTPPAALRCGEALSAVLLEATMAGLGTCPLTHV
* : ::.*** * * ** .**:.* :*:.**.:**:
MAB_3903|M.abscessus_ATCC_1997 LELTASREVVGAAIG--RSHPQALIRVGLAPTFGRIPPPTPRRSLADVFE
MUL_2417|M.ulcerans_Agy99 IESNESRDIVADLIGR-RGQPQVLIRAGITPLIEEIPAPTPRRGLDSIFE
Mb2058|M.bovis_AF2122/97 TELHASRDLVAALIGQ-PATPQALVRVGLAPEMEEPPPATPRRLIDEVFH
Rv2032|M.tuberculosis_H37Rv TELHASRDLVAALIGQ-PATPQALVRVGLAPEMEEPPPATPRRPIDEVFH
MMAR_3487|M.marinum_M TEMDAGRDTVRELTGG-QAEPQVLVRVGIAPTG-AAPELTPRRPLRDVLE
MAV_2505|M.avium_104 TELEAGRDLIRHLMADPAAVPQVLIRVGVEPEGESPPRPTPRRPLGDVLQ
MSMEG_5246|M.smegmatis_MC2_155 TELHTSRDIIGRLIVR-DACPQVLVRIGLAPALDEVPPPTPRRPVDAFLE
Mflv_3845|M.gilvum_PYR-GCK TEVPAGRDVVASVLA-TTSIPQVLVRVGAAPALDAIPAPTPRRPVHDVLE
Mvan_2550|M.vanbaalenii_PYR-1 TEVPEGRDVLASLIG-GTAIPQALVRVGLAPAMDATPPPTPRRPVREVLE
TH_3061|M.thermoresistible__bu TELPAGREIVAELIGRTAAIPQVLIRVGQVPPLREAPTPTPRRPLDEVLQ
* .*: : . **.*:* * * * **** : .:.
MAB_3903|M.abscessus_ATCC_1997 IRS----------
MUL_2417|M.ulcerans_Agy99 VRQKPEKG-----
Mb2058|M.bovis_AF2122/97 VRAKDHR------
Rv2032|M.tuberculosis_H37Rv VRAKDHR------
MMAR_3487|M.marinum_M IRR----------
MAV_2505|M.avium_104 FRPLSDR------
MSMEG_5246|M.smegmatis_MC2_155 VRPRS--------
Mflv_3845|M.gilvum_PYR-GCK IR---RGATC---
Mvan_2550|M.vanbaalenii_PYR-1 IR---GGAAC---
TH_3061|M.thermoresistible__bu IDPTPGSAPSRQG
.