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M. thermoresistible (build 8) TH_3061 (-)

annotation: 3-ketosteroid-delta4
coordinates: 4243890 - 4244951
length: 354

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3061--100% (354)3-ketosteroid-delta4
M. thermoresistible (build 8)TH_1331-1e-8351.04% (337) conserved hypothetical protein
M. thermoresistible (build 8)TH_0558-3e-2141.61% (137) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2058-4e-8952.77% (343) hypothetical protein Mb2058
M. gilvum PYR-GCKMflv_3845-8e-8551.04% (337) hypothetical protein Mflv_3845
M. tuberculosis H37RvRv2032acg3e-9053.06% (343) hypothetical protein Rv2032
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3903-4e-8349.57% (345) hypothetical protein MAB_3903
M. marinum MMMAR_3487-3e-7949.85% (343) hypothetical protein MMAR_3487
M. avium 104MAV_2505-4e-8049.26% (339) hypothetical protein MAV_2505
M. smegmatis MC2 155MSMEG_3952-1e-8150.30% (334) hypothetical protein MSMEG_3952
M. ulcerans Agy99MUL_2417-9e-7848.42% (349) hypothetical protein MUL_2417
M. vanbaalenii PYR-1Mvan_2550-3e-8549.85% (337) hypothetical protein Mvan_2550

CLUSTAL 2.0.9 multiple sequence alignment


MAB_3903|M.abscessus_ATCC_1997      -MPKTMVHIDVIQTAIQLACRAPSLHNTQPWRWIVDLGASAG----DLHL
MUL_2417|M.ulcerans_Agy99           ------MDMEVLKTAVLLACRAPSVHNSQPWRWVADRDRDSGSEVVAVHL
Mb2058|M.bovis_AF2122/97            -MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDH--------TVAL
Rv2032|M.tuberculosis_H37Rv         -MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDH--------TVAL
Mflv_3845|M.gilvum_PYR-GCK          -MSATQVRIETIIDAVDVACRAPSLHNSQPWRWVATDHG--------VDL
Mvan_2550|M.vanbaalenii_PYR-1       -MPATRIRIEAIVDALQLACRAPSLHNSQPWRWVVVDHR--------LDL
MMAR_3487|M.marinum_M               -MTETMVDTEVIARAVELASRAPSLHNSQPWRWVAASGA--------VDL
MAV_2505|M.avium_104                MMMQMTADTEVITAAIELACHAPSLHNSQPWRWVAGSTG--------VDL
MSMEG_3952|M.smegmatis_MC2_155      ----------MITEAVGLACRAPSLHNSQPWRWVDHGTS--------VDL
TH_3061|M.thermoresistible__bu      -MHDHLVELDVIRGAVQLACRAPSLHNSQPWRWVLDRWG--------LRL
                                               :  *: :*.:***:**:*****:             : *

MAB_3903|M.abscessus_ATCC_1997      YLDRTRCVTRTDGAGREAIISCGAALDHFRVAMASAGWMTRIERIPDPDN
MUL_2417|M.ulcerans_Agy99           FADRGRTVPATDHSGRETLISCGAVLDHLGVAMTAAGWQPSITRFPTPDD
Mb2058|M.bovis_AF2122/97            FLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPND
Rv2032|M.tuberculosis_H37Rv         FLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPND
Mflv_3845|M.gilvum_PYR-GCK          YADPDRMIRAADSTGREALISCGAVLDHFRVAMAAAGWSITVERLPEPSD
Mvan_2550|M.vanbaalenii_PYR-1       YVDPARVIRSADATGRQALLSCGAALDHFRVAMTAAGWNTSVRRFPDSAD
MMAR_3487|M.marinum_M               FLDPHRMVTSADDSGREAVISCGALLDHFQVAMAAAGWDSNVDLFPNPNN
MAV_2505|M.avium_104                FVDPRRTVKSADKSGREAIISCGAALDHFRVAMAAAGWSSNVAQFPNPNN
MSMEG_3952|M.smegmatis_MC2_155      FLDHHRIVRSSDSSGREAHISCGAALDHLRVAMAAAGWVIHVDRFPNPNN
TH_3061|M.thermoresistible__bu      YLDRGRIIRATDRSGREAIISCGAVLDHLRVAMLAAGWVSHIERFPNPDD
                                    : *  * :  :* :**:: :.*** ***: *** :**    :  :* . :

MAB_3903|M.abscessus_ATCC_1997      PDHLAAITFSPRTVVVV--------GDRRRADAILQRRTDRLPFETPPNW
MUL_2417|M.ulcerans_Agy99           PNHLATVDFRPIEEVTE--------TELKRAESILQRRTDRLAFDRRRYW
Mb2058|M.bovis_AF2122/97            PLHLASIDFSPADFVTE--------GHRLRADAILLRRTDRLPFAEPPDW
Rv2032|M.tuberculosis_H37Rv         PLHLASIDFSPADFVTE--------GHRLRADAILLRRTDRLPFAEPPDW
Mflv_3845|M.gilvum_PYR-GCK          PRHIASIRFAAATEVTA--------EQKRRADAILVRRTDRLPLSAPRDW
Mvan_2550|M.vanbaalenii_PYR-1       PHHLATIEFAAAGEVSY--------EQKRRADAILLRHSDRLPLAAPPDW
MMAR_3487|M.marinum_M               PDHLASIDFAAIDDIAQ--------ARRERAEAISRRRTDRRPFRAPGDW
MAV_2505|M.avium_104                LDHLASIDVVPTEYVAR--------ARRDLADAILRRRTNRLPFRAPKHW
MSMEG_3952|M.smegmatis_MC2_155      REHLANIQFSPVAHVTD--------AMRDRASAITRRRTDRLPLHPPAHW
TH_3061|M.thermoresistible__bu      PDHLASVRFSRLARLGDRSADEFLAAYRRRADVILLRHTDRRPFGAPPDP
                                      *:* : .     :               *. *  *:::* .:      

MAB_3903|M.abscessus_ATCC_1997      SQFARMLNTVIA-DRA-----VLLDVIDDVMRPKLADASALSDALRIYDS
MUL_2417|M.ulcerans_Agy99           DLFEGVLRNTID-NDI-----AMLDVLTDEQRPQLVQASHLSAALRRDDL
Mb2058|M.bovis_AF2122/97            DLVESQLRTTVT-ADT-----VRIDVIADDMRPELAAASKLTESLRLYDS
Rv2032|M.tuberculosis_H37Rv         DLVESQLRTTVT-ADT-----VRIDVIADDMRPELAAASKLTESLRLYDS
Mflv_3845|M.gilvum_PYR-GCK          DVPGETGAAGAEPDNP-----VRVHTVPGHKRDMLVEASQLAEVLRLYDS
Mvan_2550|M.vanbaalenii_PYR-1       ERLTDTLTSAAG-RGP-----AQLHVVAEDLRSPLAEVSRLAEAMRLYDA
MMAR_3487|M.marinum_M               ESFEPVLRSSVDTET------VTLAVLAEDARPRLAEASRLTEALRRYDD
MAV_2505|M.avium_104                SALEPVLRDVGRDHS------VALDVLGPDARPGLVEAARLTEALRRYDD
MSMEG_3952|M.smegmatis_MC2_155      DTVAPLVNAAIDHEA------VRFVMLADDARGRLAEASQLTESLRRYDE
TH_3061|M.thermoresistible__bu      VGVHQLLAAAAADTADTADTEVHLDVIAPEDRPRLVEASRIAESQRAADT
                                                         . .  :    *  *. .: ::   *  * 

MAB_3903|M.abscessus_ATCC_1997      AYQTELDWWTAPFTLEDGVPRSALVSAADSDRVDIGRTFPVVAERASR--
MUL_2417|M.ulcerans_Agy99           SYHAELDWWTSPFVLTDGVPPLALASDTERQRVDLSRDFPVRSHQDRR--
Mb2058|M.bovis_AF2122/97            SYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRR--
Rv2032|M.tuberculosis_H37Rv         SYHAELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRR--
Mflv_3845|M.gilvum_PYR-GCK          DYHSELFWWTADFVATEGIPRSALVSAAEGDRVGIGRTFPVTTQPERR--
Mvan_2550|M.vanbaalenii_PYR-1       RYHAELHWWTASFAEREGIPRSALITATESERVDIGRSFPVTASPERR--
MMAR_3487|M.marinum_M               AYHHELAWWTAPSRESEGIPQSALASGTAAREVAVNRSFPVDWRSESS--
MAV_2505|M.avium_104                DYHHELDWWTSPSRKFDGIPESALVSEADDRRVDVNRRFPVDPLDERS--
MSMEG_3952|M.smegmatis_MC2_155      FYHRELQWWTANVRHSDGVPAEALVSSPEAERVGVNRAFPSREHAERR--
TH_3061|M.thermoresistible__bu      PYFLELSWWTVGYDLTEGIPHGVLES-AEPQRVDVGRVFVAGSGQHRPDP
                                     *  ** ***      :*:*   * : .   .* ..* *           

MAB_3903|M.abscessus_ATCC_1997      PGLQEDQAKVLALSTARDTPKNLLRCGELLSEVLLEATLAGMATCTITHM
MUL_2417|M.ulcerans_Agy99           PEITSDWSKILVLSTPGDTRADVLRCGEVLSSVLLECTMAGMATCTLTHL
Mb2058|M.bovis_AF2122/97            PEFGHDRSKVLVLSTYDNERASLLRCGEMLSAVLLDATMAGLATCTLTHI
Rv2032|M.tuberculosis_H37Rv         PEFGHDRSKVLVLSTYDNERASLLRCGEMLSAVLLDATMAGLATCTLTHI
Mflv_3845|M.gilvum_PYR-GCK          GELESDDAAIVVLSTEDDSRESVLRCGEALSAFLLDATMTGLATCTVTHI
Mvan_2550|M.vanbaalenii_PYR-1       GHLDEDRAGVLVLSTADDSRESVLRCGEALSAVLLDATMAGMSTCTVTHV
MMAR_3487|M.marinum_M               SAGRHDHATIVVLSTPGDSRADALNCGAALSAVLLECTLAGLATCPVTHL
MAV_2505|M.avium_104                SAGSYDDAKILVLSTPEDTRADALRVGQVLSRILLECTAAGLATCPVTHV
MSMEG_3952|M.smegmatis_MC2_155      PDVARDEARIAVLITPEDTPRDAIACGEALSTILLECTMAGLATCPLTHI
TH_3061|M.thermoresistible__bu      SDNPEDHSMIVVLSTNEDTPPAALRCGEALSAVLLEATMAGLGTCPLTHV
                                         * : : .* *  :     :  *  ** .**:.* :*:.**.:**:

MAB_3903|M.abscessus_ATCC_1997      LELTASREVVGAAIG--RSHPQALIRVGLAPTFGRIPPPTPRRSLADVFE
MUL_2417|M.ulcerans_Agy99           IESNESRDIVADLIGR-RGQPQVLIRAGITPLIEEIPAPTPRRGLDSIFE
Mb2058|M.bovis_AF2122/97            TELHASRDLVAALIGQ-PATPQALVRVGLAPEMEEPPPATPRRLIDEVFH
Rv2032|M.tuberculosis_H37Rv         TELHASRDLVAALIGQ-PATPQALVRVGLAPEMEEPPPATPRRPIDEVFH
Mflv_3845|M.gilvum_PYR-GCK          TEVPAGRDVVASVLAT-TSIPQVLVRVGAAPALDAIPAPTPRRPVHDVLE
Mvan_2550|M.vanbaalenii_PYR-1       TEVPEGRDVLASLIGG-TAIPQALVRVGLAPAMDATPPPTPRRPVREVLE
MMAR_3487|M.marinum_M               TEMDAGRDTVRELTGG-QAEPQVLVRVGIAPTG-AAPELTPRRPLRDVLE
MAV_2505|M.avium_104                TELEAGRDLIRHLMADPAAVPQVLIRVGVEPEGESPPRPTPRRPLGDVLQ
MSMEG_3952|M.smegmatis_MC2_155      TEMPESRRIILDLAGT-TGIPQVLIRIGSAPPVDDVPPVTPRRSLAEVLE
TH_3061|M.thermoresistible__bu      TELPAGREIVAELIGRTAAIPQVLIRVGQVPPLREAPTPTPRRPLDEVLQ
                                     *   .*  :    .   . **.*:* *  *     *  **** : .::.

MAB_3903|M.abscessus_ATCC_1997      IRS----------
MUL_2417|M.ulcerans_Agy99           VRQKPEKG-----
Mb2058|M.bovis_AF2122/97            VRAKDHR------
Rv2032|M.tuberculosis_H37Rv         VRAKDHR------
Mflv_3845|M.gilvum_PYR-GCK          IRRGATC------
Mvan_2550|M.vanbaalenii_PYR-1       IRGGAAC------
MMAR_3487|M.marinum_M               IRR----------
MAV_2505|M.avium_104                FRPLSDR------
MSMEG_3952|M.smegmatis_MC2_155      VDR----------
TH_3061|M.thermoresistible__bu      IDPTPGSAPSRQG
                                    .