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VMMQMTADTEVITAAIELACHAPSLHNSQPWRWVAGSTGVDLFVDPRRTVKSADKSGREAIISCGAALDH FRVAMAAAGWSSNVAQFPNPNNLDHLASIDVVPTEYVARARRDLADAILRRRTNRLPFRAPKHWSALEPV LRDVGRDHSVALDVLGPDARPGLVEAARLTEALRRYDDDYHHELDWWTSPSRKFDGIPESALVSEADDRR VDVNRRFPVDPLDERSSAGSYDDAKILVLSTPEDTRADALRVGQVLSRILLECTAAGLATCPVTHVTELE AGRDLIRHLMADPAAVPQVLIRVGVEPEGESPPRPTPRRPLGDVLQFRPLSDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2505 | - | - | 100% (333) | hypothetical protein MAV_2505 |
| M. avium 104 | MAV_4111 | - | 9e-42 | 35.15% (330) | hypothetical protein MAV_4111 |
| M. avium 104 | MAV_2502 | - | 8e-40 | 32.94% (343) | hypothetical protein MAV_2502 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2058 | - | 5e-91 | 52.00% (325) | hypothetical protein Mb2058 |
| M. gilvum PYR-GCK | Mflv_3845 | - | 1e-86 | 51.25% (320) | hypothetical protein Mflv_3845 |
| M. tuberculosis H37Rv | Rv2032 | acg | 4e-92 | 52.31% (325) | hypothetical protein Rv2032 |
| M. leprae Br4923 | MLBr_01751 | - | 2e-05 | 26.28% (293) | hypothetical protein MLBr_01751 |
| M. abscessus ATCC 19977 | MAB_3903 | - | 2e-84 | 51.08% (325) | hypothetical protein MAB_3903 |
| M. marinum M | MMAR_3487 | - | 1e-116 | 64.83% (327) | hypothetical protein MMAR_3487 |
| M. smegmatis MC2 155 | MSMEG_3952 | - | 1e-93 | 55.38% (316) | hypothetical protein MSMEG_3952 |
| M. thermoresistible (build 8) | TH_1331 | - | 3e-95 | 53.73% (322) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2417 | - | 1e-84 | 50.15% (329) | hypothetical protein MUL_2417 |
| M. vanbaalenii PYR-1 | Mvan_1383 | - | 3e-86 | 49.54% (327) | hypothetical protein Mvan_1383 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2505|M.avium_104 --------------------------------------------------
MMAR_3487|M.marinum_M --------------------------------------------------
Mb2058|M.bovis_AF2122/97 --------------------------------------------------
Rv2032|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3845|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1383|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3952|M.smegmatis_MC2_155 --------------------------------------------------
TH_1331|M.thermoresistible__bu --------------------------------------------------
MUL_2417|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 MAYGCNPRGAARVSDERDVSPYARVLALDDPADAAVLQRLRADSKVDFVD
MAV_2505|M.avium_104 --------------------------------------------------
MMAR_3487|M.marinum_M --------------------------------------------------
Mb2058|M.bovis_AF2122/97 --------------------------------------------------
Rv2032|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3845|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1383|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3952|M.smegmatis_MC2_155 --------------------------------------------------
TH_1331|M.thermoresistible__bu --------------------------------------------------
MUL_2417|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 HHERQLQELLSLLPTPDPQLIAEPCRWVYYPWRHVVVSMLGPRGFRAVRL
MAV_2505|M.avium_104 --------------------------------------------------
MMAR_3487|M.marinum_M --------------------------------------------------
Mb2058|M.bovis_AF2122/97 --------------------------------------------------
Rv2032|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3845|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1383|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3952|M.smegmatis_MC2_155 --------------------------------------------------
TH_1331|M.thermoresistible__bu --------------------------------------------------
MUL_2417|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 DRNRNEITAEEQVALGRLHIGVAGLSVGHVIAHTLAAQGLCGQLRLADFD
MAV_2505|M.avium_104 --------------------------------------------------
MMAR_3487|M.marinum_M --------------------------------------------------
Mb2058|M.bovis_AF2122/97 --------------------------------------------------
Rv2032|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3845|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1383|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3952|M.smegmatis_MC2_155 --------------------------------------------------
TH_1331|M.thermoresistible__bu --------------------------------------------------
MUL_2417|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 RLELSNLNRVPATVFDLGLNKAEVAARRIAELDPYLTVRVFDNGLTFDTV
MAV_2505|M.avium_104 --------------------------------------------------
MMAR_3487|M.marinum_M --------------------------------------------------
Mb2058|M.bovis_AF2122/97 --------------------------------------------------
Rv2032|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3845|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1383|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3952|M.smegmatis_MC2_155 --------------------------------------------------
TH_1331|M.thermoresistible__bu --------------------------------------------------
MUL_2417|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 DQFLEGLDVVVEQCDSLDIKALLREGARSHGIPVLMATSDRGLIDVERFD
MAV_2505|M.avium_104 --------------------------------------------------
MMAR_3487|M.marinum_M --------------------------------------------------
Mb2058|M.bovis_AF2122/97 --------------------------------------------------
Rv2032|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3845|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1383|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3952|M.smegmatis_MC2_155 --------------------------------------------------
TH_1331|M.thermoresistible__bu --------------------------------------------------
MUL_2417|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 LEPRRSILHGLLGELDIRLLPEMSNREKIPYILRFLEAERLSPRTATTLV
MAV_2505|M.avium_104 --------------------------------------------------
MMAR_3487|M.marinum_M --------------------------------------------------
Mb2058|M.bovis_AF2122/97 --------------------------------------------------
Rv2032|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3903|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3845|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1383|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3952|M.smegmatis_MC2_155 --------------------------------------------------
TH_1331|M.thermoresistible__bu --------------------------------------------------
MUL_2417|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01751|M.leprae_Br4923 EIDRSLSTWPQLAGDVALGATAVAEAVRRIGLGEELRSGRARIDVASALN
MAV_2505|M.avium_104 ---------------MMMQMTADTEVITAAIELACHAPSLHNSQPWRWVA
MMAR_3487|M.marinum_M ----------------MTETMVDTEVIARAVELASRAPSLHNSQPWRWVA
Mb2058|M.bovis_AF2122/97 ----------------MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIA
Rv2032|M.tuberculosis_H37Rv ----------------MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIA
MAB_3903|M.abscessus_ATCC_1997 ----------------MPKTMVHIDVIQTAIQLACRAPSLHNTQPWRWIV
Mflv_3845|M.gilvum_PYR-GCK ----------------MSATQVRIETIIDAVDVACRAPSLHNSQPWRWVA
Mvan_1383|M.vanbaalenii_PYR-1 ----------------MRDVAVDIEVITEALALACRAPSLFNSQPWRWVS
MSMEG_3952|M.smegmatis_MC2_155 -------------------------MITEAVGLACRAPSLHNSQPWRWV-
TH_1331|M.thermoresistible__bu --------------------MPSVTILERALELACRAPSLHNSQPWRWIV
MUL_2417|M.ulcerans_Agy99 ---------------------MDMEVLKTAVLLACRAPSVHNSQPWRWVA
MLBr_01751|M.leprae_Br4923 QLTEPDMARHRPANPTQCSELALSGIEGVIATAAIRAPSGGNLQPWHIDA
* :*** * ***:
MAV_2505|M.avium_104 GSTGVD--------LFVDPRRTVKSADKSGREAIISCGAALDHFRVAMAA
MMAR_3487|M.marinum_M ASGAVD--------LFLDPHRMVTSADDSGREAVISCGALLDHFQVAMAA
Mb2058|M.bovis_AF2122/97 EDHTVA--------LFLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAA
Rv2032|M.tuberculosis_H37Rv EDHTVA--------LFLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAA
MAB_3903|M.abscessus_ATCC_1997 DLGASAGD----LHLYLDRTRCVTRTDGAGREAIISCGAALDHFRVAMAS
Mflv_3845|M.gilvum_PYR-GCK TDHGVD--------LYADPDRMIRAADSTGREALISCGAVLDHFRVAMAA
Mvan_1383|M.vanbaalenii_PYR-1 EGAVVS--------LFLDDARAPRYTDTTGRELVISCGIVLDHFRVAMAA
MSMEG_3952|M.smegmatis_MC2_155 ---DHGTS----VDLFLDHHRIVRSSDSSGREAHISCGAALDHLRVAMAA
TH_1331|M.thermoresistible__bu DRTDDDTE----VQLFADHRRIGRATDRSGRELVISCGAALDHLRVAMAA
MUL_2417|M.ulcerans_Agy99 DRDRDSGSEVVAVHLFADRGRTVPATDHSGRETLISCGAVLDHLGVAMTA
MLBr_01751|M.leprae_Br4923 GPDALVIR---------IAPEHTDSLDVGFRGSAVAVGAALFNARVAAAA
. * * :. * * : ** ::
MAV_2505|M.avium_104 AGWSSNVAQFPNPNNLDHLASIDVVPTEYVARARRDLADAILRRRTNRLP
MMAR_3487|M.marinum_M AGWDSNVDLFPNPNNPDHLASIDFAAIDDIAQARRERAEAISRRRTDRRP
Mb2058|M.bovis_AF2122/97 AGTTANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLRRTDRLP
Rv2032|M.tuberculosis_H37Rv AGTTANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLRRTDRLP
MAB_3903|M.abscessus_ATCC_1997 AGWMTRIERIPDPDNPDHLAAITFSPRTVVVVGDRRRADAILQRRTDRLP
Mflv_3845|M.gilvum_PYR-GCK AGWSITVERLPEPSDPRHIASIRFAAATEVTAEQKRRADAILVRRTDRLP
Mvan_1383|M.vanbaalenii_PYR-1 AGWKCNVDRFPNPNNRDHLASIDFSAMDFVTDAHRQRAEAIARRRTDRLP
MSMEG_3952|M.smegmatis_MC2_155 AGWVIHVDRFPNPNNREHLANIQFSPVAHVTDAMRDRASAITRRRTDRLP
TH_1331|M.thermoresistible__bu AGWQAGVERFPNPNNPDHLATVRFTALPAVTPAHRERAEAISARRTDRLP
MUL_2417|M.ulcerans_Agy99 AGWQPSITRFPTPDDPNHLATVDFRPIEEVTETELKRAESILQRRTDRLA
MLBr_01751|M.leprae_Br4923 HGVLGPVSLAENVDGAPLRVTLSLG--DGWNPDLAAVYEPMLVRETNRNH
* : .. . : . ..: *.*:*
MAV_2505|M.avium_104 FRAPKHWSALEPVLRD-VGRDHSVALDVLGPDARPGLVEAARLTEALRRY
MMAR_3487|M.marinum_M FRAPGDWESFEPVLRS-SVDTETVTLAVLAEDARPRLAEASRLTEALRRY
Mb2058|M.bovis_AF2122/97 FAEPPDWDLVESQLRT-TVTADTVRIDVIADDMRPELAAASKLTESLRLY
Rv2032|M.tuberculosis_H37Rv FAEPPDWDLVESQLRT-TVTADTVRIDVIADDMRPELAAASKLTESLRLY
MAB_3903|M.abscessus_ATCC_1997 FETPPNWSQFARMLNT-VIADRAVLLDVIDDVMRPKLADASALSDALRIY
Mflv_3845|M.gilvum_PYR-GCK LSAPRDWDVPGETGAAGAEPDNPVRVHTVPGHKRDMLVEASQLAEVLRLY
Mvan_1383|M.vanbaalenii_PYR-1 FAAPPDWESFIAQLSSGTAQG-SVSLHTIADGSRPELVKASELTRSARRY
MSMEG_3952|M.smegmatis_MC2_155 LHPPAHWDTVAPLVNA-AIDHEAVRFVMLADDARGRLAEASQLTESLRRY
TH_1331|M.thermoresistible__bu FDPPTDWSTVETVLRQ-NVFDDTVMLTVLGDDARPRLAEASRLSESLRRY
MUL_2417|M.ulcerans_Agy99 FDRRRYWDLFEGVLRN-TIDNDIAMLDVLTDEQRPQLVQASHLSAALRRD
MLBr_01751|M.leprae_Br4923 GKPTMVLTETIDVLHAAAVAEGARLHLLTARDDIVRAATILAAADRSRYL
. : *
MAV_2505|M.avium_104 DDDYHHELD---WWTSPSRKFDGIPES-------ALVSEADDRRVDVNRR
MMAR_3487|M.marinum_M DDAYHHELA---WWTAPSRESEGIPQS-------ALASGTAAREVAVNRS
Mb2058|M.bovis_AF2122/97 DSSYHAELF---WWTGAFETSEGIPHS-------SLVSAAESDRVTFGRD
Rv2032|M.tuberculosis_H37Rv DSSYHAELF---WWTGAFETSEGIPHS-------SLVSAAESDRVTFGRD
MAB_3903|M.abscessus_ATCC_1997 DSAYQTELD---WWTAPFTLEDGVPRS-------ALVSAADSDRVDIGRT
Mflv_3845|M.gilvum_PYR-GCK DSDYHSELF---WWTADFVATEGIPRS-------ALVSAAEGDRVGIGRT
Mvan_1383|M.vanbaalenii_PYR-1 DSKYHAELI---GWTADVAVAEGIPTG-------TLLSEAESDRVDIGRD
MSMEG_3952|M.smegmatis_MC2_155 DEFYHRELQ---WWTANVRHSDGVPAE-------ALVSSPEAERVGVNRA
TH_1331|M.thermoresistible__bu DASYHAELQ---WWTTPTWVSQGLPPD-------ALPSERERERVEIARA
MUL_2417|M.ulcerans_Agy99 DLSYHAELD---WWTSPFVLTDGVPPL-------ALASDTERQRVDLSRD
MLBr_01751|M.leprae_Br4923 TPRLHEEMISELRWPGDSFPDTGIDVRSLEMDWHQLAAFDVLRRTDVMEL
: *: *. *: * : .. . .
MAV_2505|M.avium_104 FPVDPLDERSSAGSYD----DAKILVLSTPEDTRADALRVGQVLSRILLE
MMAR_3487|M.marinum_M FPVDWRSESSSAGRHD----HATIVVLSTPGDSRADALNCGAALSAVLLE
Mb2058|M.bovis_AF2122/97 FPVVANTDRRPEFGHD----RSKVLVLSTYDNERASLLRCGEMLSAVLLD
Rv2032|M.tuberculosis_H37Rv FPVVANTDRRPEFGHD----RSKVLVLSTYDNERASLLRCGEMLSAVLLD
MAB_3903|M.abscessus_ATCC_1997 FPVVAERASRPGLQED----QAKVLALSTARDTPKNLLRCGELLSEVLLE
Mflv_3845|M.gilvum_PYR-GCK FPVTTQPERRGELESD----DAAIVVLSTEDDSRESVLRCGEALSAFLLD
Mvan_1383|M.vanbaalenii_PYR-1 FPAAGHRDRRGEIAQD----HAKVVVLSTVDETRDGFVRCGEMLSSLLLD
MSMEG_3952|M.smegmatis_MC2_155 FPSREHAERRPDVARD----EARIAVLITPEDTPRDAIACGEALSTILLE
TH_1331|M.thermoresistible__bu FPARGDSDRRPEVAED----RSTIVVLATPEDSVRDALRCGEALSALLLE
MUL_2417|M.ulcerans_Agy99 FPVRSHQDRRPEITSD----WSKILVLSTPGDTRADVLRCGEVLSSVLLE
MLBr_01751|M.leprae_Br4923 LAQWNVGAALGQDTHDRVVASSALAVISVPGHALADYARGGSAVEAIWVA
:. * : : .: . . . * :. . :
MAV_2505|M.avium_104 CTAAGLATCPVTHVTELEAGRDLIRHLMADPAAVPQVL---IRVGVEPEG
MMAR_3487|M.marinum_M CTLAGLATCPVTHLTEMDAGRDTVRELTGG-QAEPQVL---VRVGIAPTG
Mb2058|M.bovis_AF2122/97 ATMAGLATCTLTHITELHASRDLVAALIGQ-PATPQAL---VRVGLAPEM
Rv2032|M.tuberculosis_H37Rv ATMAGLATCTLTHITELHASRDLVAALIGQ-PATPQAL---VRVGLAPEM
MAB_3903|M.abscessus_ATCC_1997 ATLAGMATCTITHMLELTASREVVGAAIGR--SHPQAL---IRVGLAPTF
Mflv_3845|M.gilvum_PYR-GCK ATMTGLATCTVTHITEVPAGRDVVASVLAT-TSIPQVL---VRVGAAPAL
Mvan_1383|M.vanbaalenii_PYR-1 ATMAGLATCVLSHLTEVPESRRIVESLTGS-QAVPQVV---VRVGSAPSG
MSMEG_3952|M.smegmatis_MC2_155 CTMAGLATCPLTHITEMPESRRIILDLAGT-TGIPQVL---IRIGSAPPV
TH_1331|M.thermoresistible__bu CTMAGMATCPLTHMIEMQPSRDIVRELLDR-PGLPQVL---VRVGTTT-G
MUL_2417|M.ulcerans_Agy99 CTMAGMATCTLTHLIESNESRDIVADLIGR-RGQPQVL---IRAGITPLI
MLBr_01751|M.leprae_Br4923 AQRYGFAVQPISPVFLYAHSVDELHALSAQFADELGQLGKDFRSLARIPA
. *:*. :: : . : : .*
MAV_2505|M.avium_104 ESPPRPTPRRPLGDVLQFRPLSDR--------
MMAR_3487|M.marinum_M -AAPELTPRRPLRDVLEIRR------------
Mb2058|M.bovis_AF2122/97 EEPPPATPRRLIDEVFHVRAKDHR--------
Rv2032|M.tuberculosis_H37Rv EEPPPATPRRPIDEVFHVRAKDHR--------
MAB_3903|M.abscessus_ATCC_1997 GRIPPPTPRRSLADVFEIRS------------
Mflv_3845|M.gilvum_PYR-GCK DAIPAPTPRRPVHDVLEIRRGATC--------
Mvan_1383|M.vanbaalenii_PYR-1 DAIGSPTPRRPVADVLEIRG------------
MSMEG_3952|M.smegmatis_MC2_155 DDVPPVTPRRSLAEVLEVDR------------
TH_1331|M.thermoresistible__bu GDAPPPTPRRPLAEVVEFRG------------
MUL_2417|M.ulcerans_Agy99 EEIPAPTPRRGLDSIFEVRQKPEKG-------
MLBr_01751|M.leprae_Br4923 DNSLVLVLRLTVAGPASVRSRRSFERIRLLSG
. * : .