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NAHFPDAETLRSALSLANRAPSVHNSQPWQWRVGHESVHLYANPDLLLPHTDPDARDLMLSCGAALHHCV VALAALGWQAKIHRFPNPAEPDHLAALELRRYPAADLDVTLAAAIPRRRTDRRYYSSWPVPQGDVALMGA RAARAGVALRRVDDLAGLKRLVSAAAFQHRTDAGYLTELAAWSGRYAATAGVPARSVPAETAGAVSARAF AGGVLPQTPDTAADQDNAVVLALGTAGDDRLSWLRAGEATSVVLLTATALGLASCPITEPLEIAETREAV RRDVFGADGYPQMLLRVGWAPVNADPLPSTPRRNLSEVVVRLDDSSAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3848 | - | - | 100% (329) | hypothetical protein Mflv_3848 |
| M. gilvum PYR-GCK | Mflv_4994 | - | 1e-45 | 36.81% (326) | hypothetical protein Mflv_4994 |
| M. gilvum PYR-GCK | Mflv_3845 | - | 2e-44 | 37.88% (330) | hypothetical protein Mflv_3845 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3155 | - | 1e-115 | 63.24% (321) | hypothetical protein Mb3155 |
| M. tuberculosis H37Rv | Rv3131 | - | 1e-115 | 63.24% (321) | hypothetical protein Rv3131 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3903 | - | 4e-45 | 37.46% (323) | hypothetical protein MAB_3903 |
| M. marinum M | MMAR_3502 | - | 1e-122 | 65.34% (326) | hypothetical protein MMAR_3502 |
| M. avium 104 | MAV_2502 | - | 1e-119 | 63.19% (326) | hypothetical protein MAV_2502 |
| M. smegmatis MC2 155 | MSMEG_3955 | - | 1e-128 | 67.37% (331) | hypothetical protein MSMEG_3955 |
| M. thermoresistible (build 8) | TH_0558 | - | 5e-59 | 73.24% (142) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2421 | - | 1e-111 | 61.06% (321) | hypothetical protein MUL_2421 |
| M. vanbaalenii PYR-1 | Mvan_2547 | - | 1e-153 | 78.59% (327) | hypothetical protein Mvan_2547 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3155|M.bovis_AF2122/97 ----------------MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRV
Rv3131|M.tuberculosis_H37Rv ----------------MNTHFPDAETVRTVLTLAVRAPSIHNTQPWRWRV
MUL_2421|M.ulcerans_Agy99 MTYDSDGTACLTGKAAMNAQFPDVGTLRTVLTLATRAPSIHNTQPWRWQV
MMAR_3502|M.marinum_M ----------------MNAHFPDAGTVRTVLTLASRAPSVHNTQPWRWQV
MAV_2502|M.avium_104 ----------------MTNRFPDEGTIRTVLALASRAPSVHNTQPWRWLV
Mflv_3848|M.gilvum_PYR-GCK ----------------MNAHFPDAETLRSALSLANRAPSVHNSQPWQWRV
Mvan_2547|M.vanbaalenii_PYR-1 ----------------MTTNFPDSVTLRSALSLANRAPSVHNSQPWQWRV
MSMEG_3955|M.smegmatis_MC2_155 ----------------MNTHFPDTETIHAALALAMRAPSIHNSQPWQWRV
TH_0558|M.thermoresistible__bu ------------------------------LALAVRAPSVHNSQPWRWRV
MAB_3903|M.abscessus_ATCC_1997 ----------------MPKTMVHIDVIQTAIQLACRAPSLHNTQPWRWIV
: ** ****:**:***:* *
Mb3155|M.bovis_AF2122/97 CP----TSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQ
Rv3131|M.tuberculosis_H37Rv CP----TSLELFSRPDMQLRSTDPDGRELILSCGVALHHCVVALASLGWQ
MUL_2421|M.ulcerans_Agy99 TS----RSLELFPEPDMQLHSTDPDGRDLIISCGVALHHCVVALASMGWQ
MMAR_3502|M.marinum_M GA----TTLHLYADTSLQLPNTDPEGRDLISSCGAALNHCVIALAAVGWH
MAV_2502|M.avium_104 GQ----ESLHLYADGGRQLPNTDPDGRDLILSCGAALHHCVVGFAAVGWQ
Mflv_3848|M.gilvum_PYR-GCK GH----ESVHLYANPDLLLPHTDPDARDLMLSCGAALHHCVVALAALGWQ
Mvan_2547|M.vanbaalenii_PYR-1 GD----HSLHLFANPDLLLPHIDPDARDFMLSCGTALNHCVVALAALGWQ
MSMEG_3955|M.smegmatis_MC2_155 GE----RSVHLYADLDRHLTSTDPDSRDLLLSCGAALHHCVIAFAALGWY
TH_0558|M.thermoresistible__bu GT----ESLHLWADPEHHLPSIDPDRRDLLVSCGAALNHCIIALAALGWQ
MAB_3903|M.abscessus_ATCC_1997 DLGASAGDLHLYLDRTRCVTRTDGAGREAIISCGAALDHFRVAMASAGWM
:.*: : * *: : ***.**.* :.:*: **
Mb3155|M.bovis_AF2122/97 AKVNRFPDPKDRCHLATIGVQPLVPDQA-DVALAAAIPRRRTDRRAYSCW
Rv3131|M.tuberculosis_H37Rv AKVNRFPDPKDRCHLATIGVQPLVPDQA-DVALAAAIPRRRTDRRAYSCW
MUL_2421|M.ulcerans_Agy99 ATVTRIPDPDNSRHLASLELQAKPPDQG-DIALAAAIPRRRTDWRAYSSW
MMAR_3502|M.marinum_M AKVARLPNPADPTHLAALEVSRHTPDQL-NITLAAAIPRRRTDRRHYSFW
MAV_2502|M.avium_104 ARVTRLPNPADPDHLAAIELSGGTADPV-DIALAAAIPRRRTDRRHYSSW
Mflv_3848|M.gilvum_PYR-GCK AKIHRFPNPAEPDHLAALELRRYPAADL-DVTLAAAIPRRRTDRRYYSSW
Mvan_2547|M.vanbaalenii_PYR-1 SKVHRFPNPADPNHVAAIQVHRYPAAEL-DITLAAAIPRRRTDRRHYSPW
MSMEG_3955|M.smegmatis_MC2_155 ASVHRLPNPAEPEHLASIELRRQTPTDL-DIALAAAIPRRRTDRRHYSAW
TH_0558|M.thermoresistible__bu AKVHRFPNPAEPLHLASLELSVHKPTEA-EVSLAAAIPRRRTDRRLYSNW
MAB_3903|M.abscessus_ATCC_1997 TRIERIPDPDNPDHLAAITFSPRTVVVVGDRRRADAILQRRTDRLPFETP
: : *:*:* : *:*:: . : * ** :**** :.
Mb3155|M.bovis_AF2122/97 PVPGGDIALMAARAARGGVMLRQVSALDR--MKAIVAQAVLDHVTDEEYL
Rv3131|M.tuberculosis_H37Rv PVPGGDIALMAARAARGGVMLRQVSALDR--MKAIVAQAVLDHVTDEEYL
MUL_2421|M.ulcerans_Agy99 PVAAGDIAQMAARVARCDVALRQVEALDK--MREVVAQAVWDHATNDEYM
MMAR_3502|M.marinum_M PVPVSDVALMAARAARCGVSLRQVDATDK--LNAIVAKSVWDHAADDEYL
MAV_2502|M.avium_104 PVPVGDIALMAARAARNGVTLCQVEDADK--LHEIVKQSVWDHMN-RDYL
Mflv_3848|M.gilvum_PYR-GCK PVPQGDVALMGARAARAGVALRRVDDLAG--LKRLVSAAAFQHRTDAGYL
Mvan_2547|M.vanbaalenii_PYR-1 PVPRGDIALMGARAARAGVMLRRVDDLDA--LKRLVNEAAFQHQSDQGYL
MSMEG_3955|M.smegmatis_MC2_155 PVSHSDIAMMGARAARAGVMLRRVESLSR--LQDIVAESIARHAADDGYL
TH_0558|M.thermoresistible__bu PVPFGDIALMGARAARAGVRLLRVEDLDH--VRSAXXX------------
MAB_3903|M.abscessus_ATCC_1997 PNWSQFARMLNTVIADRAVLLDVIDDVMRPKLADASALSDALRIYDSAYQ
* : : * * * :. :
Mb3155|M.bovis_AF2122/97 RELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPAD
Rv3131|M.tuberculosis_H37Rv RELTIWSGRYGSVAGVPARNEPPSDPSAPIPGRLFAGPGLSQPSDVLPAD
MUL_2421|M.ulcerans_Agy99 RELTTWSGRYGAVAGVPARNTPPSDQDAPIPGRLFAGPGLAQPSGVSPAA
MMAR_3502|M.marinum_M AELNAWSGRHASASGVPARNTPVSDPAAPLPSRLFAGSTLAMPADAAPAD
MAV_2502|M.avium_104 VELAAWSGRYAAVAGVPARNTPKSDPGAKIPGRLFAGPMLAMPSGSSAAE
Mflv_3848|M.gilvum_PYR-GCK TELAAWSGRYAATAGVPARSVP-AETAGAVSARAFAGGVLPQTPDTAADQ
Mvan_2547|M.vanbaalenii_PYR-1 AELATWSGRYASTAGVPARNVPDGDGTGPIPLRAFAGGVLPQTPNTEPAD
MSMEG_3955|M.smegmatis_MC2_155 RELTAWSGKYASTAGVPARSAPKPEPGAPLSSRMFAGAALKQPDTGAGAD
TH_0558|M.thermoresistible__bu --------------GCTSRFR-----------------------------
MAB_3903|M.abscessus_ATCC_1997 TELDWWTAPFTLEDGVPRSALVSAADSDRVDIGRTFPVVAERASRPGLQE
* .
Mb3155|M.bovis_AF2122/97 DGAAILALGTETDDRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAK
Rv3131|M.tuberculosis_H37Rv DGAAILALGTETDDRLARLRAGEAASIVLLTATAMGLACCPITEPLEIAK
MUL_2421|M.ulcerans_Agy99 DSAVILALGTEEDDRASRLRAGEATSAVLLTATAMGLASCPITEPLEVHK
MMAR_3502|M.marinum_M DNAVMLALGTRTDDRLAQLRAGEATSVVLLTATAMGLASCPVTEPLEIAE
MAV_2502|M.avium_104 DNSVLLALGTRGDDRLARLRAGEATSMVLLTATSMGLASCPVTEPLEVAD
Mflv_3848|M.gilvum_PYR-GCK DNAVVLALGTAGDDRLSWLRAGEATSVVLLTATALGLASCPITEPLEIAE
Mvan_2547|M.vanbaalenii_PYR-1 DNAAVLALGTVEDDRLSWLRAGEATSIVLLTATALGLACCPITEPLEIAD
MSMEG_3955|M.smegmatis_MC2_155 EGAVVLALGTADDTRMSRLRAGEATSLILLTATAMGLATCPVTEPLEISE
TH_0558|M.thermoresistible__bu --------------RPTRRRRTRAVSHG------------------EAGD
MAB_3903|M.abscessus_ATCC_1997 DQAKVLALSTARDTPKNLLRCGELLSEVLLEATLAGMATCTITHMLELTA
* . * *
Mb3155|M.bovis_AF2122/97 TRDAVRAEVFGAGGYPQMLLRVGWAPINADPLPPTPRRELSQVVEWPEEL
Rv3131|M.tuberculosis_H37Rv TRDAVRAEVFGAGGYPQMLLRVGWAPINADPLPPTPRRELSQVVEWPEEL
MUL_2421|M.ulcerans_Agy99 TRQAIRKDVFGGSAYPQMLLRVGWAPINADPLPATPRRNLSRVVEWPEQL
MMAR_3502|M.marinum_M TRESVRTDVFGNNDYPQMLLRVGWAPINADPLPSTPRRPLAEIVEWMSDR
MAV_2502|M.avium_104 TREAVRTEIFGGSNYPQMLLRIGWPPINADPLPATPRRELCDFVEWMTDR
Mflv_3848|M.gilvum_PYR-GCK TREAVRRDVFGADGYPQMLLRVGWAPVNADPLPSTPRRNLSEVVVRLDDS
Mvan_2547|M.vanbaalenii_PYR-1 TREAVRRDVFGTDGHPQMLLRVGWAPVNADPLPATPRRDVTEVIAHLDGS
MSMEG_3955|M.smegmatis_MC2_155 TRDAVQAEVFGASAFPQMMLRVGWAPVNADPLPPTPRRHVADAVRWLDGS
TH_0558|M.thermoresistible__bu NREKNHSPWWASN-----LAVRGWLGN----LVFTRRG-----VEQLGSS
MAB_3903|M.abscessus_ATCC_1997 SREVVG--AAIGRSHPQALIRVGLAPTFGRIPPPTPRRSLADVFEIRS--
.*: : * * * .
Mb3155|M.bovis_AF2122/97 LRQRC--
Rv3131|M.tuberculosis_H37Rv LRQRC--
MUL_2421|M.ulcerans_Agy99 LDERG--
MMAR_3502|M.marinum_M EQCGTE-
MAV_2502|M.avium_104 EPGIAE-
Mflv_3848|M.gilvum_PYR-GCK SAE----
Mvan_2547|M.vanbaalenii_PYR-1 PIA----
MSMEG_3955|M.smegmatis_MC2_155 PFEPESE
TH_0558|M.thermoresistible__bu LGS----
MAB_3903|M.abscessus_ATCC_1997 -------