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PATRIRIEAIVDALQLACRAPSLHNSQPWRWVVVDHRLDLYVDPARVIRSADATGRQALLSCGAALDHFR VAMTAAGWNTSVRRFPDSADPHHLATIEFAAAGEVSYEQKRRADAILLRHSDRLPLAAPPDWERLTDTLT SAAGRGPAQLHVVAEDLRSPLAEVSRLAEAMRLYDARYHAELHWWTASFAEREGIPRSALITATESERVD IGRSFPVTASPERRGHLDEDRAGVLVLSTADDSRESVLRCGEALSAVLLDATMAGMSTCTVTHVTEVPEG RDVLASLIGGTAIPQALVRVGLAPAMDATPPPTPRRPVREVLEIRGGAAC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2550 | - | - | 100% (331) | hypothetical protein Mvan_2550 |
| M. vanbaalenii PYR-1 | Mvan_1383 | - | 5e-97 | 53.11% (322) | hypothetical protein Mvan_1383 |
| M. vanbaalenii PYR-1 | Mvan_2547 | - | 1e-42 | 37.62% (319) | hypothetical protein Mvan_2547 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2058 | - | 1e-105 | 56.13% (326) | hypothetical protein Mb2058 |
| M. gilvum PYR-GCK | Mflv_3845 | - | 1e-127 | 65.57% (334) | hypothetical protein Mflv_3845 |
| M. tuberculosis H37Rv | Rv2032 | acg | 1e-106 | 56.44% (326) | hypothetical protein Rv2032 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3903 | - | 9e-95 | 51.52% (330) | hypothetical protein MAB_3903 |
| M. marinum M | MMAR_3487 | - | 6e-93 | 52.76% (326) | hypothetical protein MMAR_3487 |
| M. avium 104 | MAV_2505 | - | 9e-85 | 48.28% (319) | hypothetical protein MAV_2505 |
| M. smegmatis MC2 155 | MSMEG_5246 | - | 3e-96 | 51.84% (326) | hypothetical protein MSMEG_5246 |
| M. thermoresistible (build 8) | TH_1331 | - | 2e-87 | 50.00% (318) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2417 | - | 4e-82 | 45.29% (329) | hypothetical protein MUL_2417 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1331|M.thermoresistible__bu -----MPSVTILERALELACRAPSLHNSQPWRWIVDRTDDD----TEVQL
MUL_2417|M.ulcerans_Agy99 ------MDMEVLKTAVLLACRAPSVHNSQPWRWVADRDRDSGSEVVAVHL
MMAR_3487|M.marinum_M -MTETMVDTEVIARAVELASRAPSLHNSQPWRWVAAS--------GAVDL
MAV_2505|M.avium_104 MMMQMTADTEVITAAIELACHAPSLHNSQPWRWVAGS--------TGVDL
MSMEG_5246|M.smegmatis_MC2_155 -MSDTRLDVATLANAVQLAARAPSLHNTQPWRLIAED--------GELKL
Mvan_2550|M.vanbaalenii_PYR-1 -MPATRIRIEAIVDALQLACRAPSLHNSQPWRWVVVDHRLD--------L
Mflv_3845|M.gilvum_PYR-GCK -MSATQVRIETIIDAVDVACRAPSLHNSQPWRWVATDHGVD--------L
Mb2058|M.bovis_AF2122/97 -MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVA--------L
Rv2032|M.tuberculosis_H37Rv -MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVA--------L
MAB_3903|M.abscessus_ATCC_1997 -MPKTMVHIDVIQTAIQLACRAPSLHNTQPWRWIVDLGASAG----DLHL
: *: :*.:***:**:**** :. *
TH_1331|M.thermoresistible__bu FADHRRIGRATDRSGRELVISCGAALDHLRVAMAAAGWQAGVERFPNPNN
MUL_2417|M.ulcerans_Agy99 FADRGRTVPATDHSGRETLISCGAVLDHLGVAMTAAGWQPSITRFPTPDD
MMAR_3487|M.marinum_M FLDPHRMVTSADDSGREAVISCGALLDHFQVAMAAAGWDSNVDLFPNPNN
MAV_2505|M.avium_104 FVDPRRTVKSADKSGREAIISCGAALDHFRVAMAAAGWSSNVAQFPNPNN
MSMEG_5246|M.smegmatis_MC2_155 FLDPSRVVRSTDRSSREAVMSCGVLLDHLRVALAAAGWDTEVQRFPNPND
Mvan_2550|M.vanbaalenii_PYR-1 YVDPARVIRSADATGRQALLSCGAALDHFRVAMTAAGWNTSVRRFPDSAD
Mflv_3845|M.gilvum_PYR-GCK YADPDRMIRAADSTGREALISCGAVLDHFRVAMAAAGWSITVERLPEPSD
Mb2058|M.bovis_AF2122/97 FLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPND
Rv2032|M.tuberculosis_H37Rv FLDKDRVLYATDHSGREALLGCGAVLDHFRVAMAAAGTTANVERFPNPND
MAB_3903|M.abscessus_ATCC_1997 YLDRTRCVTRTDGAGREAIISCGAALDHFRVAMASAGWMTRIERIPDPDN
: * * :* :.*: ::.**. ***: **:::** : :* . :
TH_1331|M.thermoresistible__bu PDHLATVRFTALPAVTPAHRERAEAISARRTDRLPFDPPTDWSTVETVLR
MUL_2417|M.ulcerans_Agy99 PNHLATVDFRPIEEVTETELKRAESILQRRTDRLAFDRRRYWDLFEGVLR
MMAR_3487|M.marinum_M PDHLASIDFAAIDDIAQARRERAEAISRRRTDRRPFRAPGDWESFEPVLR
MAV_2505|M.avium_104 LDHLASIDVVPTEYVARARRDLADAILRRRTNRLPFRAPKHWSALEPVLR
MSMEG_5246|M.smegmatis_MC2_155 RDHLATLSFRPLQFVTEGHRKRADAILARRTDRLPMSAYVDWDAFETLLR
Mvan_2550|M.vanbaalenii_PYR-1 PHHLATIEFAAAGEVSYEQKRRADAILLRHSDRLPLAAPPDWERLTDTLT
Mflv_3845|M.gilvum_PYR-GCK PRHIASIRFAAATEVTAEQKRRADAILVRRTDRLPLSAPRDWDVPGETGA
Mb2058|M.bovis_AF2122/97 PLHLASIDFSPADFVTEGHRLRADAILLRRTDRLPFAEPPDWDLVESQLR
Rv2032|M.tuberculosis_H37Rv PLHLASIDFSPADFVTEGHRLRADAILLRRTDRLPFAEPPDWDLVESQLR
MAB_3903|M.abscessus_ATCC_1997 PDHLAAITFSPRTVVVVGDRRRADAILQRRTDRLPFETPPNWSQFARMLN
*:*:: . . : *::* *:::* .: *.
TH_1331|M.thermoresistible__bu QNVF-DDTVMLTVLGDDARPRLAEASRLSESLRRYDASYHAELQWWTTPT
MUL_2417|M.ulcerans_Agy99 NTID-NDIAMLDVLTDEQRPQLVQASHLSAALRRDDLSYHAELDWWTSPF
MMAR_3487|M.marinum_M SSVD-TETVTLAVLAEDARPRLAEASRLTEALRRYDDAYHHELAWWTAPS
MAV_2505|M.avium_104 DVGR-DHSVALDVLGPDARPGLVEAARLTEALRRYDDDYHHELDWWTSPS
MSMEG_5246|M.smegmatis_MC2_155 ARLG-DGPVHMDTLGEDVREEVAEAAALTESLRLYDAAYHSELAWWTTPF
Mvan_2550|M.vanbaalenii_PYR-1 SAAG-RGPAQLHVVAEDLRSPLAEVSRLAEAMRLYDARYHAELHWWTASF
Mflv_3845|M.gilvum_PYR-GCK AGAEPDNPVRVHTVPGHKRDMLVEASQLAEVLRLYDSDYHSELFWWTADF
Mb2058|M.bovis_AF2122/97 TTVT-ADTVRIDVIADDMRPELAAASKLTESLRLYDSSYHAELFWWTGAF
Rv2032|M.tuberculosis_H37Rv TTVT-ADTVRIDVIADDMRPELAAASKLTESLRLYDSSYHAELFWWTGAF
MAB_3903|M.abscessus_ATCC_1997 TVIA-DRAVLLDVIDDVMRPKLADASALSDALRIYDSAYQTELDWWTAPF
. : .: * :. .: *: :* * *: ** ***
TH_1331|M.thermoresistible__bu WVSQGLPPDALPSERERERVEIARAFPARGDSDRRPEVAEDRSTIVVLAT
MUL_2417|M.ulcerans_Agy99 VLTDGVPPLALASDTERQRVDLSRDFPVRSHQDRRPEITSDWSKILVLST
MMAR_3487|M.marinum_M RESEGIPQSALASGTAAREVAVNRSFPVDWRSESSSAGRHDHATIVVLST
MAV_2505|M.avium_104 RKFDGIPESALVSEADDRRVDVNRRFPVDPLDERSSAGSYDDAKILVLST
MSMEG_5246|M.smegmatis_MC2_155 ATEDGIPQTALISAEESERVAVSRDFPVAPHSSRRPALNNDAATIVVLST
Mvan_2550|M.vanbaalenii_PYR-1 AEREGIPRSALITATESERVDIGRSFPVTASPERRGHLDEDRAGVLVLST
Mflv_3845|M.gilvum_PYR-GCK VATEGIPRSALVSAAEGDRVGIGRTFPVTTQPERRGELESDDAAIVVLST
Mb2058|M.bovis_AF2122/97 ETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLST
Rv2032|M.tuberculosis_H37Rv ETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLST
MAB_3903|M.abscessus_ATCC_1997 TLEDGVPRSALVSAADSDRVDIGRTFPVVAERASRPGLQEDQAKVLALST
:*:* :* : .* . * **. * : ::.*:*
TH_1331|M.thermoresistible__bu PEDSVRDALRCGEALSALLLECTMAGMATCPLTHMIEMQPSRDIVRELLD
MUL_2417|M.ulcerans_Agy99 PGDTRADVLRCGEVLSSVLLECTMAGMATCTLTHLIESNESRDIVADLIG
MMAR_3487|M.marinum_M PGDSRADALNCGAALSAVLLECTLAGLATCPVTHLTEMDAGRDTVRELTG
MAV_2505|M.avium_104 PEDTRADALRVGQVLSRILLECTAAGLATCPVTHVTELEAGRDLIRHLMA
MSMEG_5246|M.smegmatis_MC2_155 DGYSREDALDAGEGLSKVLLECTMSGLATCPVTHVTELHTSRDIIGRLIV
Mvan_2550|M.vanbaalenii_PYR-1 ADDSRESVLRCGEALSAVLLDATMAGMSTCTVTHVTEVPEGRDVLASLIG
Mflv_3845|M.gilvum_PYR-GCK EDDSRESVLRCGEALSAFLLDATMTGLATCTVTHITEVPAGRDVVASVLA
Mb2058|M.bovis_AF2122/97 YDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIG
Rv2032|M.tuberculosis_H37Rv YDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIG
MAB_3903|M.abscessus_ATCC_1997 ARDTPKNLLRCGELLSEVLLEATLAGMATCTITHMLELTASREVVGAAIG
. * * ** .**:.* :*::**.:**: * .*: :
TH_1331|M.thermoresistible__bu R-PGLPQVLVRVGTT-TGGDAPPPTPRRPLAEVVEFRG-----
MUL_2417|M.ulcerans_Agy99 R-RGQPQVLIRAGITPLIEEIPAPTPRRGLDSIFEVRQKPEKG
MMAR_3487|M.marinum_M G-QAEPQVLVRVGIAPTG-AAPELTPRRPLRDVLEIRR-----
MAV_2505|M.avium_104 DPAAVPQVLIRVGVEPEGESPPRPTPRRPLGDVLQFRPLSDR-
MSMEG_5246|M.smegmatis_MC2_155 R-DACPQVLVRIGLAPALDEVPPPTPRRPVDAFLEVRPRS---
Mvan_2550|M.vanbaalenii_PYR-1 G-TAIPQALVRVGLAPAMDATPPPTPRRPVREVLEIRGGAAC-
Mflv_3845|M.gilvum_PYR-GCK T-TSIPQVLVRVGAAPALDAIPAPTPRRPVHDVLEIRRGATC-
Mb2058|M.bovis_AF2122/97 Q-PATPQALVRVGLAPEMEEPPPATPRRLIDEVFHVRAKDHR-
Rv2032|M.tuberculosis_H37Rv Q-PATPQALVRVGLAPEMEEPPPATPRRPIDEVFHVRAKDHR-
MAB_3903|M.abscessus_ATCC_1997 R--SHPQALIRVGLAPTFGRIPPPTPRRSLADVFEIRS-----
. **.*:* * * **** : ....*