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MTNRGVGVQFDELTRVYGATRALDGLTLHIEPGELVALLGPSGGGKTTALRILAGLDEATSGTVSVGGVD VGRVPANKRDMGMVFQAYSLFPHLTVLDNVAFGLKMRGKGKSDRLSRAADMLDLVGLGELGGRYANELSG GQQQRVALARALAIRPRVLLLDEPLSALDAKVRTQLRDEIRRVQLEVGTTTLFVTHDQEEALAVADRVGV MNQGRLEQLAAPADLYAHPATPFVADFVGLNNKVPASVSGGTATLLGVSVPALPGSVDGDGVAMVRPEAV TVAADPAGTATVATVSFLGAITRVGITMPDGSLLSAQMSSTAARALTPGDPVTVGVEPGGVLVTRPL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1083 | - | - | 100% (347) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3138 | - | 8e-71 | 41.78% (359) | spermidine/putrescine ABC transporter ATPase subunit |
| M. gilvum PYR-GCK | Mflv_3778 | - | 2e-67 | 43.03% (337) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 4e-66 | 44.79% (326) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 4e-66 | 44.79% (326) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01424 | - | 5e-56 | 43.88% (278) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1655 | - | 4e-68 | 47.06% (323) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 1e-66 | 44.11% (331) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 1e-66 | 45.10% (337) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_6521 | - | 1e-141 | 77.06% (340) | sulfate/thiosulfate import ATP-binding protein CysA 2 |
| M. thermoresistible (build 8) | TH_2424 | - | 1e-65 | 42.69% (335) | PUTATIVE sulfate ABC transporter, ATPase subunit |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 1e-65 | 43.50% (331) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_5739 | - | 1e-169 | 88.89% (342) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1083|M.gilvum_PYR-GCK -----------MTNRGVGVQFDELTRVYG--ATRALDGLTLHIEPGELVA
Mvan_5739|M.vanbaalenii_PYR-1 ---------MSVGTNGVGVQLDELTRVYG--TTRALDGFTLHIEPGELVA
MSMEG_6521|M.smegmatis_MC2_155 --MSTPGTGAAGATSGVAVELVDLTRSYG--SVKALDGLSLRMEPGELVA
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYG--DFVALDHVDFVVPTGSLTA
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYG--DFVALDHVDFVVPTGSLTA
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYG--DFVALDHVDFVVPAGSLTA
MUL_3658|M.ulcerans_Agy99 ------MTGPGT--GGHAIVVRDAFKQYG--DFVALDHVDFVVPAGSLTA
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYG--DFVALDHVDFVVPTGSLTA
TH_2424|M.thermoresistible__bu ------MT--------DAITVRGANKRYG--DFAALDNVDFAVPAGSLTA
MAB_1655|M.abscessus_ATCC_1997 ------MT------AENTITVRGANKHYG--DFAALDNIDFDVPSGSLTA
MLBr_01424|M.leprae_Br4923 ---------------MASVTFEQATRQFPDTDRPALDRLDLDVDDGEFVV
: . : : *** . : : *.:..
Mflv_1083|M.gilvum_PYR-GCK LLGPSGGGKTTALRILAGLDEATSGTVSVGGVDVGRVPANKRDMGMVFQA
Mvan_5739|M.vanbaalenii_PYR-1 LLGPSGCGKTTALRILAGLDEATSGTVAVGGVDVSKVPANKRDMGMVFQA
MSMEG_6521|M.smegmatis_MC2_155 LLGPSGCGKTTALRILAGLDEATSGTVLVDGRDVSSVPANKRDMGMVFQA
Mb2419c|M.bovis_AF2122/97 LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQH
Rv2397c|M.tuberculosis_H37Rv LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTRVPPQRRGIGFVFQH
MMAR_3715|M.marinum_M LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQH
MUL_3658|M.ulcerans_Agy99 LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTRVPPQRRGIGFVFQH
MAV_1785|M.avium_104 LLGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTRVPPQRRGIGFVFQH
TH_2424|M.thermoresistible__bu LLGPSGSGKSTLLRAIAGLDRPDTGTITINGRDVTDVPPQRRGIGFVFQH
MAB_1655|M.abscessus_ATCC_1997 LLGPSGSGKSTLLRSIAGLDNPDSGTITINGRDVTGVPPQRRDIGFVFQH
MLBr_01424|M.leprae_Br4923 VVGPSGCGKTTSLRMVAGLETLDSGCIRIGDRDVTHVDPKDRDVAMVFQN
::**** **:* ** :***: :* : : . ** * .: *.:.:***
Mflv_1083|M.gilvum_PYR-GCK YSLFPHLTVLDNVAFGLKMRGKGKSDRLSRAADMLDLVGLGELGGRYANE
Mvan_5739|M.vanbaalenii_PYR-1 YSLFPHLTVLDNVAFGLKMRGKAKRDRLSRAADMLELVGLGELGGRYAKE
MSMEG_6521|M.smegmatis_MC2_155 YSLFPHLTVLDNVAFGLKMRGKSKRDRLSTAADMLDLVGLGAHKNKYANE
Mb2419c|M.bovis_AF2122/97 YAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQ
Rv2397c|M.tuberculosis_H37Rv YAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSGFQSRYPNQ
MMAR_3715|M.marinum_M YAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPNQ
MUL_3658|M.ulcerans_Agy99 YAAFKHLTVRDNVAYGLKIRKRPKAEIRDKVDNLLEVVGLSGFHGRYPDQ
MAV_1785|M.avium_104 YAAFKHLTVRDNVAYGLKVRKRPKAEIKAKVDNLLEVVGLSGFQGRYPNQ
TH_2424|M.thermoresistible__bu YAAFKHLTVRDNVAFGLKIRRRPKREIAEKVDNLLEVVGLAGFQNRYPNQ
MAB_1655|M.abscessus_ATCC_1997 YAAFKHLTVWENVAFGLKIRKKPKAEIKKKVDDLLEVVGLSGFHTRYPAQ
MLBr_01424|M.leprae_Br4923 YALYPHMTVAQNLGFALKISKISKAEIHDRILVVAKLLDLQPYLDRKPKD
*: : *:** :*:.:.**: * : : .::.* : . :
Mflv_1083|M.gilvum_PYR-GCK LSGGQQQRVALARALAIRPRVLLLDEPLSALDAKVRTQLRDEIRRVQLEV
Mvan_5739|M.vanbaalenii_PYR-1 LSGGQQQRVALARALAIRPRVLLLDEPLSALDAKVRTQLRDEIRRVQLEV
MSMEG_6521|M.smegmatis_MC2_155 LSGGQQQRVALARALAIAPRVLLLDEPLSALDAKVRAQLRDEIRRVQLEV
Mb2419c|M.bovis_AF2122/97 LSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEV
Rv2397c|M.tuberculosis_H37Rv LSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEV
MMAR_3715|M.marinum_M LSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEV
MUL_3658|M.ulcerans_Agy99 LSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEV
MAV_1785|M.avium_104 LSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEV
TH_2424|M.thermoresistible__bu LSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREDLRTWLRRLHEEV
MAB_1655|M.abscessus_ATCC_1997 LSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEV
MLBr_01424|M.leprae_Br4923 LSGGQRQRVAMGRAIVRRPQVFLMDEPLSNLDAKLRAQTRNQIAELQCQL
*****:**:*:.**:. *.*:*:***:. ****:* : * : .:: ::
Mflv_1083|M.gilvum_PYR-GCK GTTTLFVTHDQEEALAVADRVGVMNQGRLEQLAAPADLYAHPATPFVADF
Mvan_5739|M.vanbaalenii_PYR-1 GTTTLFVTHDQEEALAVADRVGVMNEGRLEQLAAPADLYANPATPFVAEF
MSMEG_6521|M.smegmatis_MC2_155 GTTTLFVTHDQEEALAVADRVGVMSQGKLEQLAAPAELYANPATPFVAEF
Mb2419c|M.bovis_AF2122/97 HVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSF
Rv2397c|M.tuberculosis_H37Rv HVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSF
MMAR_3715|M.marinum_M HVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFVMSF
MUL_3658|M.ulcerans_Agy99 HVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSF
MAV_1785|M.avium_104 HVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSF
TH_2424|M.thermoresistible__bu HVTTVLVTHDQSEALDVADRIAVLNNGRIEQVGSPAEVYDSPANEFVMSF
MAB_1655|M.abscessus_ATCC_1997 HVTTVLVTHDQAEALDVADRIAVLNKGRIEQVGSPEDLYDRPANSFVMSF
MLBr_01424|M.leprae_Br4923 GTTTVYVTHDQVEAMTMGDRVAVLCYGVLQQFATPRELYHKPENVFVAGF
.**: ***** **: :.**:.*: * ::*..:* ::* * . ** *
Mflv_1083|M.gilvum_PYR-GCK VGLNNK--VPASVSGGTATLLGVSVPALPGSVD-GDGVAMVRPEAVTVAA
Mvan_5739|M.vanbaalenii_PYR-1 VGLNNK--VPATVSGGSASLLGVSVAALPGSVD-GAGVAMVRPESVTVTA
MSMEG_6521|M.smegmatis_MC2_155 VGLHNK--IPAEVTDGKARVLGATVPTLAGSVGSGAGTAMVRPESVTVQA
Mb2419c|M.bovis_AF2122/97 LG-------------AVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGST
Rv2397c|M.tuberculosis_H37Rv LG-------------AVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGST
MMAR_3715|M.marinum_M LG-------------AVSALNGALVRPHDIRVGRTPEMAVAAADGTGEST
MUL_3658|M.ulcerans_Agy99 LG-------------AVSALNGALVRPHDIRVGRTPEMAVAAADGTGEST
MAV_1785|M.avium_104 LG-------------AVSTLNGTLVRPHDIRVGRTPEMAVAAEDGTAEST
TH_2424|M.thermoresistible__bu LG-------------AVSSLNGTLVRPHDIWVGRHPELPTS--DSTLQAT
MAB_1655|M.abscessus_ATCC_1997 LG-------------PVAKLNGILVRPHDIRVGRNADLARAAAEGTGETT
MLBr_01424|M.leprae_Br4923 IGSPGMNLVTLSIVDSSVLLGDWPIRIPREIASAASEVIIGVRPEHFELG
:* : . : ..
Mflv_1083|M.gilvum_PYR-GCK DPAGTATVATVSFLGAITRVGIT-MPDGSLLSAQMSS--TAARALTPGDP
Mvan_5739|M.vanbaalenii_PYR-1 DPAGASTVSSVSFLGAISRVHIM-VPDGSTVSAQMAS--SAARGFAPGDP
MSMEG_6521|M.smegmatis_MC2_155 DPDGNATVASVAFLGPISRVYVN-LPDGPVIHAQLPS--SQARAFEAGQT
Mb2419c|M.bovis_AF2122/97 G-VLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDT
Rv2397c|M.tuberculosis_H37Rv G-VLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDT
MMAR_3715|M.marinum_M G-VTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDT
MUL_3658|M.ulcerans_Agy99 G-VTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDT
MAV_1785|M.avium_104 G-VARAIVDRVVKLGFEVRVELTSAATGGPFTAQITRGDAEALALREGDT
TH_2424|M.thermoresistible__bu G-VVRARIDRVVMLGFEVRLELTSATNNAPFTAQITRGDAEALGLRSGDT
MAB_1655|M.abscessus_ATCC_1997 G-VTKATVDRVVYLGFEVRVELTSAATGEQFTAQITRGDAEALGLREGDP
MLBr_01424|M.leprae_Br4923 SLGVEVEIDMVEELGADAYLYGRIAGASKVTDQLVVARVDGRNPPAKGSR
. : : ** : . : *.
Mflv_1083|M.gilvum_PYR-GCK VTVGVEPGG-------------------VLVTRPL-----
Mvan_5739|M.vanbaalenii_PYR-1 VTVGIEPRG-------------------VLVTRP------
MSMEG_6521|M.smegmatis_MC2_155 VSVGLEPAP-------------------VLVV--------
Mb2419c|M.bovis_AF2122/97 VYVRATRVPPIAG---GVSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv VYVRATRVPPIAG---GVSGVDDAGVERVKVTST------
MMAR_3715|M.marinum_M VYVRATRVPPIAG---AAPAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 VYVRATRVPPIAG---AAPAVPDDGAGSTPRAAQIGVGGQ
MAV_1785|M.avium_104 VYVRATRVPPITAGATTVPAVSRDGADEATLTSA------
TH_2424|M.thermoresistible__bu VYVRATRVP----------ALPTGDVDERVAAR-------
MAB_1655|M.abscessus_ATCC_1997 VYVRVTRVP---------------DVGELAEVAS------
MLBr_01424|M.leprae_Br4923 VRLYTEPGNVHFFG-----------VDGHRIS--------
* :