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ASVSFEQATRRYPGTDRPALDRLDLIVGDGEFVVLVGPSGCGKTTSLRMVAGLETLDCGRIRIGERDVTE VDPKDRDVAMVFQNYALYPHMTVAQNMGFALKVAKIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQR QRVAMGRAIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHDQVEAMTMGDRVAVLSD GVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFRLSIADSTVSLGDWQILLPRAVVGTAAEVIIGVRPEH LELGGAGIEMDVDMVEELGADAYLYGRIVSGGCEMDQSIVARVDGRGPPERGSRVRLCPTPGHLHFFAVD GRRIPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2038c | - | - | 100% (357) | Probable sugar-transport ATP-binding protein ABC transporter |
| M. tuberculosis H37Rv | Rv2832c | ugpC | e-104 | 56.78% (354) | sn-glycerol-3-phosphate transport ATP-binding protein ABC |
| M. tuberculosis H37Rv | Rv1238 | sugC | 7e-94 | 55.28% (322) | sugar-transport ATP-binding protein ABC transporter SugC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2064c | - | 0.0 | 100.00% (357) | sugar-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3854 | - | 5e-85 | 52.50% (320) | ABC transporter related |
| M. leprae Br4923 | MLBr_01424 | - | 1e-161 | 79.72% (355) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1375 | - | 8e-92 | 48.68% (378) | sugar ABC transporter, ATP-binding protein SugC |
| M. marinum M | MMAR_3011 | - | 1e-167 | 82.54% (355) | sugar-transport ATP-binding protein ABC transporter |
| M. avium 104 | MAV_2479 | - | 1e-169 | 82.82% (355) | glycerol-phosphate porter |
| M. smegmatis MC2 155 | MSMEG_5571 | - | 1e-108 | 60.16% (364) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3215 | - | 1e-108 | 60.06% (363) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_2252 | - | 1e-167 | 82.25% (355) | sugar-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_4484 | - | 1e-93 | 50.79% (378) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2038c|M.tuberculosis_H37Rv --MASVSFEQATRRYPGTDRPALDRLDLIVGDGEFVVLVGPSGCGKTTSL
Mb2064c|M.bovis_AF2122/97 --MASVSFEQATRRYPGTDRPALDRLDLIVGDGEFVVLVGPSGCGKTTSL
MMAR_3011|M.marinum_M --MASVSFEGATRRYPGADRPAVDSLDLEVDDGEFVVLVGPSGCGKTTSL
MUL_2252|M.ulcerans_Agy99 --MASVSFEGATRRYPGADRPAVDSLDLVVDDGEFVVLVGPSGCGKTTSL
MAV_2479|M.avium_104 MSMASVTFQQATRRYPGADRPALDNLNLVVGDGEFVVLVGPSGCGKTTSL
MLBr_01424|M.leprae_Br4923 --MASVTFEQATRQFPDTDRPALDRLDLDVDDGEFVVVVGPSGCGKTTSL
MSMEG_5571|M.smegmatis_MC2_155 --MAAITYRNASCIYEGSDKLAVDSLNLDIADGEFVVLVGPSGSGKSTAL
TH_3215|M.thermoresistible__bu --MATITYRNASCIYEGSDTFAVNSLNLEIEDGEFVVLVGPSGSGKSTAL
MAB_1375|M.abscessus_ATCC_1997 --MAEIVLNQVSKTYTDG-SAAVRDVSLNIADGEFIILVGPSGCGKSTTL
Mvan_4484|M.vanbaalenii_PYR-1 --MAEIVLDRVTKSYADG-TAAVKDLSITVADGEFVTLVGPSGCGKSTTL
Mflv_3854|M.gilvum_PYR-GCK --MAAITMRNIVKKYGDG-YPAVNDVSLDIADGEFVILVGPSGCGKSTLL
** : : . *: :.: : ****: :*****.**:* *
Rv2038c|M.tuberculosis_H37Rv RMVAGLETLDCGRIRIGERDVTEVDPKDRDVAMVFQNYALYPHMTVAQNM
Mb2064c|M.bovis_AF2122/97 RMVAGLETLDCGRIRIGERDVTEVDPKDRDVAMVFQNYALYPHMTVAQNM
MMAR_3011|M.marinum_M RMLAGLERVDAGRIRIAERDVTNVDPKSRDVAMVFQNYALYPHMTVAQNM
MUL_2252|M.ulcerans_Agy99 RMLAGLEKVDAGRIRIAERDVTNVDPKSRDVAMVFQNYALYPHMTVAQNM
MAV_2479|M.avium_104 RMVAGLETVDSGRILIGDRDVTNVDPKQRDVAMVFQNYALYPHMTVAQNM
MLBr_01424|M.leprae_Br4923 RMVAGLETLDSGCIRIGDRDVTHVDPKDRDVAMVFQNYALYPHMTVAQNL
MSMEG_5571|M.smegmatis_MC2_155 RMLAGLEDIDEGDIEIGGRNMRGVPSKDRDIAMVFQNYALYPTKTVAENM
TH_3215|M.thermoresistible__bu RMLAGLEDIDDGDIEIGGRNMRGVPSKDRDIAMVFQNYALYPNKTVAENM
MAB_1375|M.abscessus_ATCC_1997 NMIAGLEDISSGELTIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNI
Mvan_4484|M.vanbaalenii_PYR-1 NMIAGLEEITSGELRIDGERVNERSTKDRDIAMVFQSYALYPHMTVRQNI
Mflv_3854|M.gilvum_PYR-GCK RMIVGLEDITSGDMMIGDKRVNDMAPRDRNLAMVFQNYALYPHLTVFENI
.*:.*** : * : * . : .:.*::*****.***** ** :*:
Rv2038c|M.tuberculosis_H37Rv GFALKVA-KIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQRQRVAMG
Mb2064c|M.bovis_AF2122/97 GFALKVA-KIGKAEIRERVLAAAKLLDLQSYLDRKPKDLSGGQRQRVAMG
MMAR_3011|M.marinum_M GFALKVA-KTPKAEIRDRVLQAAKLLDLEAYLDRKPKDLSGGQRQRVAMG
MUL_2252|M.ulcerans_Agy99 GFALKVA-KTPKAEIRDRVLQAAKLLDLEAYLDRKPKDLSGGQRQRVAMG
MAV_2479|M.avium_104 GFAMKIA-KTPKAQIRERVLDAAKLLDLQPYLDRKPKDLSGGQRQRVAMG
MLBr_01424|M.leprae_Br4923 GFALKIS-KISKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMG
MSMEG_5571|M.smegmatis_MC2_155 GFALKLR-GVPAAERRKKVEEAAKLLDLEQFLDRKPAKLSGGQRQRVAMG
TH_3215|M.thermoresistible__bu GFALKLR-GVAASERRRKVEEAAKLLDLTEFLDRKPAKLSGGQRQRVAMG
MAB_1375|M.abscessus_ATCC_1997 AFPLTLA-KMSKDDINAKVAEAAKILDLTDYLDRKPANLSGGQRQRVAMG
Mvan_4484|M.vanbaalenii_PYR-1 GFPLTLA-KLSRQEIAEKVEQTAKTLDLTDLLDRKPDQLSGGQRQRVAMG
Mflv_3854|M.gilvum_PYR-GCK AFPLRLAGKLSDDEIRQRVNDAATTLELGEHLDRKPANLSGGQRQRVAMG
.*.: : : :: .*. *:* ***** .************
Rv2038c|M.tuberculosis_H37Rv RAIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHDQV
Mb2064c|M.bovis_AF2122/97 RAIVRRPQVFLMDEPLSNLDAKLRGQTRNQIAALQRQLGTTTVYVTHDQV
MMAR_3011|M.marinum_M RAIVRRPQVFLMDEPLSNLDAKLRVQTRNQIAGLQRQLGTTTVYVTHDQV
MUL_2252|M.ulcerans_Agy99 RAIVRRPQVFLMDEPLSNLDTKLRVQTRNQIAGLQRQLGTTTVYVTHDQV
MAV_2479|M.avium_104 RAIVRRPQVFLMDEPLSNLDAKLRVQTRNQIAALQRRLGTTTVYVTHDQV
MLBr_01424|M.leprae_Br4923 RAIVRRPQVFLMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQV
MSMEG_5571|M.smegmatis_MC2_155 RAIVREPQVFCMDEPLSNLDAKLRVQTRTQIAALQRRLGTTTVYVTHDQV
TH_3215|M.thermoresistible__bu RAIVREPQVFCMDEPLSNLDAKLRVQTRTQIAALQRRLGTTTVYVTHDQV
MAB_1375|M.abscessus_ATCC_1997 RAIVRSPKAFLMDEPLSNLDAKLRVQMRTEIARLQKRLGTTTVYVTHDQT
Mvan_4484|M.vanbaalenii_PYR-1 RAIVRNPKAFLMDEPLSNLDAKLRVQMRGEIARLQKRLGTTTVYVTHDQT
Mflv_3854|M.gilvum_PYR-GCK RAIVREADAFLFDEPLSNLDAKLRGQMRTEILRLQRKLGVTTVYVTHDQT
***** ...* :********:*** * * :* ** :**.*********.
Rv2038c|M.tuberculosis_H37Rv EAMTMGDRVAVLSDGVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFRLS
Mb2064c|M.bovis_AF2122/97 EAMTMGDRVAVLSDGVLQQCASPRELYRNPGNVFVAGFIGSPAMNLFRLS
MMAR_3011|M.marinum_M EAMTMGDRVAVLCDGVLQQCAAPRELYRRPDNVFVAGFIGSPAMNMFILP
MUL_2252|M.ulcerans_Agy99 EAMTMGDRVAVLCDGVLQQCAAPRELYRRPDNVFVAGFIGSPAMNMFILP
MAV_2479|M.avium_104 EAMTMGDRVAVLRDGVLQQFAPPRELYRNPSNVFVAGFIGSPAMNLFTLP
MLBr_01424|M.leprae_Br4923 EAMTMGDRVAVLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLS
MSMEG_5571|M.smegmatis_MC2_155 EAMTMGDRVAVLRNGKLQQFASPNELYDKPVNEFVAGFIGSPAMNLVKLP
TH_3215|M.thermoresistible__bu EAMTMGDRVAVLKHGRLQQFASPGDLYHRPANAFVAGFIGSPAMNLFNAQ
MAB_1375|M.abscessus_ATCC_1997 EAMTLGDRVVVLRAGKVQQVGAPQELYDTPANLFVAGFIGSPSMNFFPAT
Mvan_4484|M.vanbaalenii_PYR-1 EAMTLGDRVVVMLGGAVQQIGTPDELYRGPANLFVAGFIGSPAMNFFPAA
Mflv_3854|M.gilvum_PYR-GCK EAMTLGDRVAVLKKGVLQQVASPRELYDQPVNLFVAGFIGSPPMNFVPAR
****:****.*: * :** ..* :** * * ********* **:.
Rv2038c|M.tuberculosis_H37Rv IADSTVSLGD-WQILLPRAVVGTA------AEVIIGVRPEHLELGGAG--
Mb2064c|M.bovis_AF2122/97 IADSTVSLGD-WQILLPRAVVGTA------AEVIIGVRPEHLELGGAG--
MMAR_3011|M.marinum_M IVDSSVLLGD-WLIQLPREVTVPA------PEVVVGVRPEHFEVGNLG--
MUL_2252|M.ulcerans_Agy99 IVDSSVLLGD-WLIQLPREVTVPA------PEVVVGVRPEHFEVGNLG--
MAV_2479|M.avium_104 VVDSAVSLGD-WPIALPREIAAAA------SEVVVGVRPEHFELGGLG--
MLBr_01424|M.leprae_Br4923 IVDSSVLLGD-WPIRIPREIASAA------SEVIIGVRPEHFELGSLG--
MSMEG_5571|M.smegmatis_MC2_155 IVPDGVRVGDNSTLELERDQMTRLSQ-LGLSEVTIGIRPEQLEIEESGR-
TH_3215|M.thermoresistible__bu LVPEGVQIGD-TVLELERAQLTALHE-AKLDTVTVGLRPEHLELSDAGG-
MAB_1375|M.abscessus_ATCC_1997 LTDVGVQLPF-GEVTLDAGLYAGITARKPSGDVIVGIRPEQFEDAALVDT
Mvan_4484|M.vanbaalenii_PYR-1 LTEIGVRLPF-GEIPLTGQVYERLKGHRTCDDLIAGIRPEHLEDAAVIDA
Mflv_3854|M.gilvum_PYR-GCK VTGNEIELPF-ATVPLRDEWRGSVEEGKVY---IAGIRPGAFEDAEFVDT
:. : : : : *:** :*
Rv2038c|M.tuberculosis_H37Rv --------IEMDVDMVEELGADAYLYGRIVSGGCEMDQS-----------
Mb2064c|M.bovis_AF2122/97 --------IEMDVDMVEELGADAYLYGRIVSGGCEMDQS-----------
MMAR_3011|M.marinum_M --------VEMEIDVVEELGADAYLYGRIINGGAMIDQS-----------
MUL_2252|M.ulcerans_Agy99 --------VEMEIDVVEELGADAYLYGRISNGGTMIDQS-----------
MAV_2479|M.avium_104 --------VEMEVDVVEELGADAYLYGRITGSGKVIDAP-----------
MLBr_01424|M.leprae_Br4923 --------VEVEIDMVEELGADAYLYGRIAGASKVTDQL-----------
MSMEG_5571|M.smegmatis_MC2_155 --------VEVVVDLVEDLGSEAYVYTHAASGSGVE--------------
TH_3215|M.thermoresistible__bu --------VEVVVDLVEDLGSEAYLYTH--TGSGVD--------------
MAB_1375|M.abscessus_ATCC_1997 YKRITGLTLTVNADVVESLGSDKYVHFTTEGGAAHSDELTELAQE--SEV
Mvan_4484|M.vanbaalenii_PYR-1 YARIGALVFDVTVEMVESLGADKYVYFGVDGPGAEAVQLTEVAAE--STV
Mflv_3854|M.gilvum_PYR-GCK DKASRGVTFDVEIDVTEWLGNEQYAFVPFEATTEISGQLAELANELDSEQ
. : ::.* ** : * .
Rv2038c|M.tuberculosis_H37Rv ----IVARVDGRGPPERGSRVRLCPTP-GHLHFFAVD-GRRIPG------
Mb2064c|M.bovis_AF2122/97 ----IVARVDGRGPPERGSRVRLCPTP-GHLHFFAVD-GRRIPG------
MMAR_3011|M.marinum_M ----VVARADGSNPPERGSRVRLYPQP-AQLHFFTVD-GRRIA-------
MUL_2252|M.ulcerans_Agy99 ----VVARADGSNPPERGSRVRLYPQP-AQLHFFTVD-GRRIA-------
MAV_2479|M.avium_104 ----IVARVDGRNPPEKGSRVRLHPAP-GHLHFFGRN-GQRIGVRGSW--
MLBr_01424|M.leprae_Br4923 ----VVARVDGRNPPAKGSRVRLYTEP-GNVHFFGVD-GHRIS-------
MSMEG_5571|M.smegmatis_MC2_155 ----LVARCNPRRAPKLAQTVRLRKSPDGVVHLFHPDTGERI--------
TH_3215|M.thermoresistible__bu ----LVARCLDRVPAKLADTVRLRKRTDGVVHLFHPDTGERVGE------
MAB_1375|M.abscessus_ATCC_1997 AENEFVARLSAASKVAEGQPIELIIDT-GKLVIFDAESGENLS-------
Mvan_4484|M.vanbaalenii_PYR-1 GENEFVARVPAQSGAAVGRTLQLALNP-DNVLLFDPRTGANLS-------
Mflv_3854|M.gilvum_PYR-GCK LRTQICVELDPLSRVRSGDKATLWLDS-ERLHLFDPHSGDNLTRVSHERP
. .. . * . : :* * .:
Rv2038c|M.tuberculosis_H37Rv -----------------
Mb2064c|M.bovis_AF2122/97 -----------------
MMAR_3011|M.marinum_M -----------------
MUL_2252|M.ulcerans_Agy99 -----------------
MAV_2479|M.avium_104 -----------------
MLBr_01424|M.leprae_Br4923 -----------------
MSMEG_5571|M.smegmatis_MC2_155 -----------------
TH_3215|M.thermoresistible__bu -----------------
MAB_1375|M.abscessus_ATCC_1997 -----------LAATAE
Mvan_4484|M.vanbaalenii_PYR-1 -----------LPAVGA
Mflv_3854|M.gilvum_PYR-GCK REQNPPESRGRHAATAG