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LDLCPAGGQAGRMTTYVLIPGMCHGAWCFDQLSESLRQRGHRVLAVTLTGVAERSHLMPGGVNLDTHIAD VLAVIDSDAAAAGDLVLVAHSYGGMVITGVADRIPDRVDSLVFVDAVVPRDGEACWDLVNDEERQWYVDV DDTGFGVPPMPFFDPRATAHPLATVLQGLRLTGDLSRFRRRVYVYAREWPGESPLQSSFERVRDDPSWVT YELDGRHNLMRDCPDELLGILLATAER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3566 | - | - | 100% (237) | hypothetical protein Mflv_3566 |
| M. gilvum PYR-GCK | Mflv_2476 | - | 1e-09 | 31.82% (110) | esterase EstC, putative |
| M. gilvum PYR-GCK | Mflv_4502 | - | 4e-05 | 37.50% (72) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3228 | lipV | 4e-05 | 32.84% (67) | lipase LipV |
| M. tuberculosis H37Rv | Rv3203 | lipV | 4e-05 | 32.84% (67) | lipase LipV |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3517 | - | 3e-06 | 38.27% (81) | putative hydrolase, alpha/beta fold LipV |
| M. marinum M | MMAR_0223 | - | 9e-05 | 34.55% (110) | oxidoreductase |
| M. avium 104 | MAV_2604 | - | 5e-08 | 35.34% (116) | hydrolase, alpha/beta fold family protein, putative |
| M. smegmatis MC2 155 | MSMEG_3842 | - | 2e-92 | 69.33% (225) | putative esterase |
| M. thermoresistible (build 8) | TH_1085 | - | 7e-78 | 60.99% (223) | putative esterase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3363 | - | 1e-107 | 78.57% (224) | hypothetical protein Mvan_3363 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3566|M.gilvum_PYR-GCK --------MDLCPAGGQAGRMTTYVLIPGMCHGAWCFDQLSESLRQRGHR
Mvan_3363|M.vanbaalenii_PYR-1 --------------------MSSYVLIPGMCHGAWCFDEVAASLRSAGHH
MSMEG_3842|M.smegmatis_MC2_155 --------------------MTTFVLVPGMCHGAWCFDTVTAALRAAGHE
TH_1085|M.thermoresistible__bu --------------------MSTFVLVPGACHGAWWYDDLADRLRAHGHW
Mb3228|M.bovis_AF2122/97 -----------------------------------------------MPE
Rv3203|M.tuberculosis_H37Rv -----------------------------------------------MPE
MAB_3517|M.abscessus_ATCC_1997 ---------MTPTLNIHRYGPVEPARLLALHGLTGHGRRWAPLFDEYLAD
MAV_2604|M.avium_104 ------------------MALPDLVLVHGGEHAGDCWDLVIAELRRQEPG
MMAR_0223|M.marinum_M MPTIDINAGTIHYEVTGPEHGRPVMFVHGYLMGGQLWRQVSERLAKRGLR
Mflv_3566|M.gilvum_PYR-GCK VLAVTLTGVAERSHL-MPGGVNLDTHIADVLAVIDSDAAAAGDLVLVAHS
Mvan_3363|M.vanbaalenii_PYR-1 VLALTLTGVGERSHL-MPGGVNLDTHIVDVLAAIDNDAATGADLILVGHS
MSMEG_3842|M.smegmatis_MC2_155 VLAVTPTGVAERAHL-QHAGVNLDTHITDVVAVVEAYAAEP--VVLVGHS
TH_1085|M.thermoresistible__bu VLAICPTGVGERAHL-LHAGVNLDTHITDVLAALHAHRVRD--AVLVGHS
Mb3228|M.bovis_AF2122/97 IPIAAPDLLGHGRSP-WAAPWTIDANVSALAALLDNQGDGP--VVVVGHS
Rv3203|M.tuberculosis_H37Rv IPIAAPDLLGHGRSP-WAAPWTIDANVSALAALLDNQGDGP--VVVVGHS
MAB_3517|M.abscessus_ATCC_1997 VPVLAPDLLGHGRSP-ATAPWSLEAHADAVAAELDTAETGP--IVVVGHS
MAV_2604|M.avium_104 LRTLAVDLPGHGNKPGDLATVTIADWVDSVIADIEEAGLGD--IVIVGHS
MMAR_0223|M.marinum_M CFAPTWPLGAHPRALGPDADRSITGVGDLVADVLATLDLHD--VVLVGND
.. . .: : : ::*.:.
Mflv_3566|M.gilvum_PYR-GCK YGGMVITGVADRI-PDRVDSLVFVDA--------------VVPRDGEACW
Mvan_3363|M.vanbaalenii_PYR-1 YGGMVITGVADRI-PDRVDSLVFLDA--------------VVPRDGEACW
MSMEG_3842|M.smegmatis_MC2_155 YGGMVITGAADRI-PDTVDALVYLDA--------------VVPRDGESCA
TH_1085|M.thermoresistible__bu YGGMVITGVADRA-GPRVDSLVYLDA--------------FVPRDGESCW
Mb3228|M.bovis_AF2122/97 FGGAVAMHLAAAR-PDQVAALVLLDP--------------AVALDGSRVR
Rv3203|M.tuberculosis_H37Rv FGGAVAMHLAAAR-PDQVAALVLLDP--------------AVALDGSRVR
MAB_3517|M.abscessus_ATCC_1997 FGGAIALHLAARR-PDLVKSLVLLDP--------------AIGLDGDWMR
MAV_2604|M.avium_104 MAGVTVPGVVAKLGSSRVREMVLATA--------------FVPPQGSAIA
MMAR_0223|M.marinum_M TGGVVAQLVAVRH-PERLGALVLTSCDAFEHFPPPILKPVILAAKSKKMF
.* . : :* : ...
Mflv_3566|M.gilvum_PYR-GCK DLVND-----EERQ-WYVDVDDTGFGVPPMPFFDPRATAHPLATVLQGLR
Mvan_3363|M.vanbaalenii_PYR-1 DLVND-----EERQ-WYVKVDDSGFGVPPMPFFDDRATSHPLATVLQPLR
MSMEG_3842|M.smegmatis_MC2_155 DLVND-----EERR-WYMETDASGFGVPPLEFFDPRATPHPRASVLQPLR
TH_1085|M.thermoresistible__bu TLTTD-----DQRA-WYGSVDATGLAVPPLPFFDERATGHPLAALMQPIR
Mb3228|M.bovis_AF2122/97 EVVDA-----MLASPDYLDPAEARAEKATGAWADVDPPVLDAELDEHLVA
Rv3203|M.tuberculosis_H37Rv EVVDA-----MLASPDYLDPAEARAEKATGAWADVDPPVLDAELDEHLVA
MAB_3517|M.abscessus_ATCC_1997 QIADQ-----MVTYPDYTDRAEAKSDKVAGAWSDVPDHVIEAELDEHLIQ
MAV_2604|M.avium_104 DTLGGPLAVFARRAARIGRPMKIPAPAARWAFCNGMTAAQRRLTMSKLQA
MMAR_0223|M.marinum_M RAAIQTMRSPAARRRAYGDLAHADIDELAQRWVQPALSNPAIAEDLRQLT
: : :
Mflv_3566|M.gilvum_PYR-GCK LTGDLSRFR-RRVYVYAREWPGES---------PLQSSFERVRDDP-SWV
Mvan_3363|M.vanbaalenii_PYR-1 LRGDLNGFR-RRIFVYALDWPGES---------PLRPSYDRVRDDP-TWI
MSMEG_3842|M.smegmatis_MC2_155 IGVDVNRFR-RRVFVYARDWPGES---------PLQASYDRVRNDP-NWT
TH_1085|M.thermoresistible__bu LSGTLESIR-RRVYVYATGWDGES---------PLRPTYERLRRDP-AWT
Mb3228|M.bovis_AF2122/97 LPNGRYGWR-ISLPAMVCYWSELARDIVLPPVGTATTLVRAVRASP-AYV
Rv3203|M.tuberculosis_H37Rv LPNGRYGWR-ISLPAMVCYWSELARDIVLPPVGTATTLVRAVRASP-AYV
MAB_3517|M.abscessus_ATCC_1997 LSNGRCGWR-MNLPAAVTAWSELARDIVLPVNVIRTTLLLATRTSP-PYV
MAV_2604|M.avium_104 ESARVPGEP-VDRSGLPADVPRTWILTTRDRALSVASQHASIAALGGVET
MMAR_0223|M.marinum_M LSLHTDVTRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAATIPNARL
Mflv_3566|M.gilvum_PYR-GCK TYELDGRHNLMRDCPDELLGILLATAER------------------
Mvan_3363|M.vanbaalenii_PYR-1 CHELDGRHNLMRDRPADLLRILLSASQS------------------
MSMEG_3842|M.smegmatis_MC2_155 CHELDAKHNLMRDAPEELLRILVDVASR------------------
TH_1085|M.thermoresistible__bu THALDAPHNLLREHTDAVLRILLDTAVPASGTKLQHVSV-------
Mb3228|M.bovis_AF2122/97 SDQLLAALDKRLGADFELLDFDCGHMVPQAKPTEVAAVIRSRLGPR
Rv3203|M.tuberculosis_H37Rv SDQLLAALDKRLGADFELLDFDCGHMVPQAKPTEVAAVIRSRLGPR
MAB_3517|M.abscessus_ATCC_1997 LPKLLDALQATLGSQFELIDIDCDHMVSQSRPAETAAAIRSHLE--
MAV_2604|M.avium_104 VIPVDACHEVMFSHPERLAQILIERCRLRGVGIR------------
MMAR_0223|M.marinum_M ELIEGARTFSMLDRPDRLADLLSAVAVRT-----------------
: :