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MTTFVLVPGMCHGAWCFDTVTAALRAAGHEVLAVTPTGVAERAHLQHAGVNLDTHITDVVAVVEAYAAEP VVLVGHSYGGMVITGAADRIPDTVDALVYLDAVVPRDGESCADLVNDEERRWYMETDASGFGVPPLEFFD PRATPHPRASVLQPLRIGVDVNRFRRRVFVYARDWPGESPLQASYDRVRNDPNWTCHELDAKHNLMRDAP EELLRILVDVASR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3842 | - | - | 100% (223) | putative esterase |
| M. smegmatis MC2 155 | MSMEG_1797 | - | 1e-13 | 35.71% (112) | salicylate esterase |
| M. smegmatis MC2 155 | MSMEG_6658 | - | 3e-09 | 33.33% (168) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3228 | lipV | 4e-07 | 38.46% (65) | lipase LipV |
| M. gilvum PYR-GCK | Mflv_3566 | - | 2e-92 | 69.33% (225) | hypothetical protein Mflv_3566 |
| M. tuberculosis H37Rv | Rv3203 | lipV | 4e-07 | 38.46% (65) | lipase LipV |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0768 | - | 4e-07 | 38.26% (115) | hypothetical protein MAB_0768 |
| M. marinum M | MMAR_1355 | lipV | 2e-06 | 34.85% (66) | lipase LipV |
| M. avium 104 | MAV_2604 | - | 5e-06 | 32.14% (112) | hydrolase, alpha/beta fold family protein, putative |
| M. thermoresistible (build 8) | TH_1085 | - | 1e-79 | 61.99% (221) | putative esterase |
| M. ulcerans Agy99 | MUL_2524 | lipV | 3e-07 | 36.36% (66) | lipase LipV |
| M. vanbaalenii PYR-1 | Mvan_3363 | - | 3e-93 | 69.96% (223) | hypothetical protein Mvan_3363 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3566|M.gilvum_PYR-GCK MDLCPAGGQAGRMTTYVLIPGMCHGAWCFDQLSESLRQRGHRVLAVTLTG
Mvan_3363|M.vanbaalenii_PYR-1 ------------MSSYVLIPGMCHGAWCFDEVAASLRSAGHHVLALTLTG
MSMEG_3842|M.smegmatis_MC2_155 ------------MTTFVLVPGMCHGAWCFDTVTAALRAAGHEVLAVTPTG
TH_1085|M.thermoresistible__bu ------------MSTFVLVPGACHGAWWYDDLADRLRAHGHWVLAICPTG
Mb3228|M.bovis_AF2122/97 ---------------------------------------MPEIPIAAPDL
Rv3203|M.tuberculosis_H37Rv ---------------------------------------MPEIPIAAPDL
MMAR_1355|M.marinum_M --MSTDLHVHRYGPEEPVRVLTIHGVTEHGQSWEYLAGYLPEVSIAAPDL
MUL_2524|M.ulcerans_Agy99 --MSTDLHVHRYGPEEPVRVLTIHGVTEHGQSWEYLAGYLPEVNIAAPDL
MAB_0768|M.abscessus_ATCC_1997 ---------MSSKPTIVLVHGFWGGAAHWGNVIVELHGRGFEDLHAVEN-
MAV_2604|M.avium_104 ----------MALPDLVLVHGGEHAGDCWDLVIAELRRQEPGLRTLAVDL
Mflv_3566|M.gilvum_PYR-GCK VAERSHLMPGG-VNLDTHIADVLAVIDSDAAAAGDLVLVAHSYGGMVITG
Mvan_3363|M.vanbaalenii_PYR-1 VGERSHLMPGG-VNLDTHIVDVLAAIDNDAATGADLILVGHSYGGMVITG
MSMEG_3842|M.smegmatis_MC2_155 VAERAHLQHAG-VNLDTHITDVVAVVEAYAAEP--VVLVGHSYGGMVITG
TH_1085|M.thermoresistible__bu VGERAHLLHAG-VNLDTHITDVLAALHAHRVRD--AVLVGHSYGGMVITG
Mb3228|M.bovis_AF2122/97 LGHGRSPWAAP-WTIDANVSALAALLDNQGDGP--VVVVGHSFGGAVAMH
Rv3203|M.tuberculosis_H37Rv LGHGRSPWAAP-WTIDANVSALAALLDNQGDGP--VVVVGHSFGGAVAMH
MMAR_1355|M.marinum_M LGHGRSSWAAP-WSIDANVSALAALLKDQADGP--VVVVGHSFGGAVALQ
MUL_2524|M.ulcerans_Agy99 LGHGRSSWAAP-WSIDANVSALAALLKDQADGP--VVVVGHSFGGAVALQ
MAB_0768|M.abscessus_ATCC_1997 ------PLTSL-ADDAARTRQMVQQIDGP------VLLVGHSYGGAVITE
MAV_2604|M.avium_104 PGHGNKPGDLATVTIADWVDSVIADIEEAGLGD--IVIVGHSMAGVTVPG
: :. ::*.** .* .
Mflv_3566|M.gilvum_PYR-GCK VADRIPD-RVDSLVFVDAVVPRDGEACWDLVNDE--ERQ-WYVDV-DDTG
Mvan_3363|M.vanbaalenii_PYR-1 VADRIPD-RVDSLVFLDAVVPRDGEACWDLVNDE--ERQ-WYVKV-DDSG
MSMEG_3842|M.smegmatis_MC2_155 AADRIPD-TVDALVYLDAVVPRDGESCADLVNDE--ERR-WYMET-DASG
TH_1085|M.thermoresistible__bu VADRAGP-RVDSLVYLDAFVPRDGESCWTLTTDD--QRA-WYGSV-DATG
Mb3228|M.bovis_AF2122/97 LAAARPD-QVAALVLLDPAVALDGSRVREVVDAM--LASPDYLDP-AEAR
Rv3203|M.tuberculosis_H37Rv LAAARPD-QVAALVLLDPAVALDGSRVREVVDAM--LASPDYLDP-AEAR
MMAR_1355|M.marinum_M LAAAHPD-LVAALILLDPAIGLNGSRVREVVDAM--VAFPDYTDP-AEAR
MUL_2524|M.ulcerans_Agy99 LAAAHPD-LVAALILLDPAIGLDGSRVREVVDAM--VAFPDYTDP-AEAR
MAB_0768|M.abscessus_ATCC_1997 AGDLPN---VAGLVYVAAFAPDAGESPGQLTEQLPPAAAANLVPD-SDGY
MAV_2604|M.avium_104 VVAKLGSSRVREMVLATAFVPPQGSAIADTLGGPLAVFARRAARIGRPMK
* :: . *.
Mflv_3566|M.gilvum_PYR-GCK FGVPPMPFFDPRATAHPL-ATVLQGLRLTGDLSRFRR---RVYVYAR--E
Mvan_3363|M.vanbaalenii_PYR-1 FGVPPMPFFDDRATSHPL-ATVLQPLRLRGDLNGFRR---RIFVYAL--D
MSMEG_3842|M.smegmatis_MC2_155 FGVPPLEFFDPRATPHPR-ASVLQPLRIGVDVNRFRR---RVFVYAR--D
TH_1085|M.thermoresistible__bu LAVPPLPFFDERATGHPL-AALMQPIRLSGTLESIRR---RVYVYAT--G
Mb3228|M.bovis_AF2122/97 AEKATGAWADVDPPVLDA-ELDEHLVALPNGRYGWRISLPAMVCYWS--E
Rv3203|M.tuberculosis_H37Rv AEKATGAWADVDPPVLDA-ELDEHLVALPNGRYGWRISLPAMVCYWS--E
MMAR_1355|M.marinum_M MERAYGAWADVDPAVLDA-ELDEHLITLPNGRYSWRISLPAMVCYWS--E
MUL_2524|M.ulcerans_Agy99 MERAYGAWADVDPAVLDA-ELDEHLITLPNGRYSWRISLPAMVCYWS--E
MAB_0768|M.abscessus_ATCC_1997 LWIKQDKFRESFAQDLPEDAALVMAVTQKAPLASTFGDAITAPAWRNKPS
MAV_2604|M.avium_104 IPAPAARWAFCNGMTAAQRRLTMSKLQAESARVPGEPVDRSGLPADVPRT
: :
Mflv_3566|M.gilvum_PYR-GCK WPGESPLQSS------FERVRDDPSWVTYELDGRHNLMRDCPDELLGILL
Mvan_3363|M.vanbaalenii_PYR-1 WPGESPLRPS------YDRVRDDPTWICHELDGRHNLMRDRPADLLRILL
MSMEG_3842|M.smegmatis_MC2_155 WPGESPLQAS------YDRVRNDPNWTCHELDAKHNLMRDAPEELLRILV
TH_1085|M.thermoresistible__bu WDGESPLRPT------YERLRRDPAWTTHALDAPHNLLREHTDAVLRILL
Mb3228|M.bovis_AF2122/97 LARDIVLPPVGTATTLVRAVRASPAYVSDQLLAALDKRLGADFELLDFDC
Rv3203|M.tuberculosis_H37Rv LARDIVLPPVGTATTLVRAVRASPAYVSDQLLAALDKRLGADFELLDFDC
MMAR_1355|M.marinum_M LARDAALPPPGIATTLVRAVRADPQYVSDELIAALRERLGADFALREFEC
MUL_2524|M.ulcerans_Agy99 LARDAALPPPGIATTLVRAVRADPQYVSDELIAALRERLGADFALREFEC
MAB_0768|M.abscessus_ATCC_1997 WYQVSTQDRMINPENERRMAQRIKPRKTIELDASHASLASQPVAIADLIA
MAV_2604|M.avium_104 WILTTRDRALSVASQHASIAALGGVETVIPVDACHEVMFSHPERLAQILI
: . : :
Mflv_3566|M.gilvum_PYR-GCK ATAER------------------
Mvan_3363|M.vanbaalenii_PYR-1 SASQS------------------
MSMEG_3842|M.smegmatis_MC2_155 DVASR------------------
TH_1085|M.thermoresistible__bu DTAVPASGTKLQHVSV-------
Mb3228|M.bovis_AF2122/97 GHMVPQAKPTEVAAVIRSRLGPR
Rv3203|M.tuberculosis_H37Rv GHMVPQAKPTEVAAVIRSRLGPR
MMAR_1355|M.marinum_M GHMVPQAKPTEVATLIREQLKTP
MUL_2524|M.ulcerans_Agy99 GHMVPQAKPTEVATLIREQLKTP
MAB_0768|M.abscessus_ATCC_1997 EAAGDIA----------------
MAV_2604|M.avium_104 ERCRLRGVGIR------------