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TVVDETPDTPTGPVADPAPVIEISDVWKLHKLGDEVVKALMAAELTVMPGEFVCLMGPSGSGKSTLLNII GGLDRPTKGNVRIAGTDTATLTESQYAALRHDTIGFIFQSYNLIPFLSAVENVELPLMFEPYDRKALRKR AIELLELVGLGHRINHQPTRMSGGEQQRTAIARSLISNPALVLADEPTANLDHRTGETVVRMLRDLCSTM GVTVVASTHDPTVADEASRVVRMKDGQIVN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4127 | - | - | 100% (241) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3165 | - | 3e-34 | 40.09% (227) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_4448 | - | 9e-31 | 36.63% (202) | type II secretory pathway family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1012 | - | 3e-46 | 42.53% (221) | adhesion component transport ATP-binding protein ABC |
| M. tuberculosis H37Rv | Rv0986 | - | 3e-46 | 42.53% (221) | adhesion component transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_00669 | ftsE | 4e-32 | 38.61% (202) | putative cell division ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_4671c | - | 4e-49 | 43.53% (232) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0922 | - | 4e-43 | 41.28% (235) | ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_4425 | - | 2e-45 | 40.45% (220) | ABC-type transporter, ATPase component |
| M. smegmatis MC2 155 | MSMEG_2524 | - | 1e-116 | 86.31% (241) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_4101 | - | 8e-45 | 43.04% (230) | PUTATIVE putative ABC transporter, ATP-binding protein |
| M. ulcerans Agy99 | MUL_0674 | - | 5e-42 | 40.85% (235) | ABC transporter, ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_2216 | - | 1e-120 | 90.04% (241) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1012|M.bovis_AF2122/97 MNRQ---------------PIVQLSNLSWTFREGETRRQVLDHITFDFEP
Rv0986|M.tuberculosis_H37Rv MNRQ---------------PIVQLSNLSWTFREGETRRQVLDHITFDFEP
Mflv_4127|M.gilvum_PYR-GCK MTVVDETPDTPTGPVADPAPVIEISDVWKLHKLGDEVVKALMAAELTVMP
Mvan_2216|M.vanbaalenii_PYR-1 MTALDDTAGT--------APVIEISDVWKLHKLGDEVVKALMAAELTVTP
MSMEG_2524|M.smegmatis_MC2_155 MTALDDTEAPADNE-DSRKPVIEISDVWKLHKLGDEVVKALKAAELQVMP
MAB_4671c|M.abscessus_ATCC_199 MNSPERPNVSP-------EPVLQLKGVAHQYGTGAAAVHALRGLDLTVNT
MMAR_0922|M.marinum_M MTRAQAPTSPR--------GGVSLHGVDKTFGTAAASVHALRGIDLDIEP
MUL_0674|M.ulcerans_Agy99 MTRAQAPTSPR--------GGVSLHGVDKTFGTAAASVHALRRIDLDIEP
MAV_4425|M.avium_104 MT-------------------IEMAGVVREYRVGGQPVRALDRISLQLAG
TH_4101|M.thermoresistible__bu VTDSGEDRDT---------AVIEARDLCKSFGQGAAETPILKHVDVRISP
MLBr_00669|M.leprae_Br4923 --------------------MITLDHVSKKYKS--LARPALDNVNVKIDK
: : . * . .
Mb1012|M.bovis_AF2122/97 GEFVALLGQSGSGKSTLLNLISGIEKPTTGDVTINGFAITQKTERDRTLF
Rv0986|M.tuberculosis_H37Rv GEFVALLGQSGSGKSTLLNLISGIEKPTTGDVTINGFAITQKTERDRTLF
Mflv_4127|M.gilvum_PYR-GCK GEFVCLMGPSGSGKSTLLNIIGGLDRPTKGNVRIAGTDTATLTESQYAAL
Mvan_2216|M.vanbaalenii_PYR-1 GEFVCLMGPSGSGKSTLLNIIGGLDRPTKGTVKIAGQDTATLTESQYAAL
MSMEG_2524|M.smegmatis_MC2_155 GEFVCLMGPSGSGKSTLLNIIGGLDRPTKGTVKISGQDTAQLTESQFAAL
MAB_4671c|M.abscessus_ATCC_199 GEVVLVVGPSGGGKTTALLVMGLLLTPVSGLVRIGGRDVGELAERDRAHI
MMAR_0922|M.marinum_M GELVAIVGESGSGKTTLLNVIGGIEEANSGSINVAGQDISGCRPRALSKF
MUL_0674|M.ulcerans_Agy99 GELVAIVGESGSGKTTLLNVIGGIEEANSGSINVAGQDISGCRPRALSKF
MAV_4425|M.avium_104 GQFVAVVGPSGAGKSTLLHLLGALDSPDSGSILFDGEEIGRLGDEAQSRF
TH_4101|M.thermoresistible__bu GEFVVLIGPSGSGKSTLLSILGLLEPPSSGRLFVDQQDVSGLSRRQLARL
MLBr_00669|M.leprae_Br4923 GEFVFLIGPSGSGKSTFMRLLLGAETPTSGDVRVSKFHVNKLPGRHIPRL
*:.* ::* **.**:* : :: . .* : . . :
Mb1012|M.bovis_AF2122/97 RRDQIGIVFQFFNLIPTLTVLENITLPQELAGVSQRKAAVVARDLLEKVG
Rv0986|M.tuberculosis_H37Rv RRDQIGIVFQFFNLIPTLTVLENITLPQELAGVSQRKAAVVARDLLEKVG
Mflv_4127|M.gilvum_PYR-GCK RHDTIGFIFQSYNLIPFLSAVENVELPLMFEPYDRKALRKRAIELLELVG
Mvan_2216|M.vanbaalenii_PYR-1 RHDTIGFIFQSYNLIPFLSAVENVELPLMFEPYDRKSLRKRATELLELVG
MSMEG_2524|M.smegmatis_MC2_155 RHDTIGFIFQSYNLIPFLSAVENVELPLMFEPYDRKSLRTRATELLEMVG
MAB_4671c|M.abscessus_ATCC_199 RLEKLGFLFQEYNLLNALTSAENVALPLRYAGVSKDKAMSRARGLLADVG
MMAR_0922|M.marinum_M RRDHVGFIFQFFNLIPTLTAKENVEVIVELTG-RGDRRR--ATELLDAVG
MUL_0674|M.ulcerans_Agy99 RRDHVGFIFQFFNLIPTLTAKENVEVIVELTG-RGDRRR--ATELLDAVE
MAV_4425|M.avium_104 RHRRVGFVFQFFNLLPTLSAWENVAIPRLLDGVRLGRARPDALRLLERVG
TH_4101|M.thermoresistible__bu RGRKLGYVFQSFNLLAGLSVAENVMLSGLLVGESGRAQYERAVELLDEFG
MLBr_00669|M.leprae_Br4923 R-QVIGCVFQDFRLLQQKTVYENVAFALEVIGRRSDAINQVVPDVLETVG
* :* :** :.*: : **: . . :* .
Mb1012|M.bovis_AF2122/97 MADRERTFPDKLSGGEQQRVAISRALAHNPMLVLADEPTGNLDSDTGDKV
Rv0986|M.tuberculosis_H37Rv MADRERTFPDKLSGGEQQRVAISRALAHNPMLVLADEPTGNLDSDTGDKV
Mflv_4127|M.gilvum_PYR-GCK LGHRINHQPTRMSGGEQQRTAIARSLISNPALVLADEPTANLDHRTGETV
Mvan_2216|M.vanbaalenii_PYR-1 LGHRVNHQPTKMSGGEQQRTAIARSLISSPTLVLADEPTANLDHRTGETV
MSMEG_2524|M.smegmatis_MC2_155 LGHRIHHQPTKMSGGEQQRTAIARSLISNPTLVLADEPTANLDHRTGETV
MAB_4671c|M.abscessus_ATCC_199 MEHRTDHRPPALSGGEKQRVAAARALVARPGLVLADEPTANLDSATGKRV
MMAR_0922|M.marinum_M LADRAGSFPGQLSGGQQQRVAIARALITDPDLLLADEPMGALDVATGRRV
MUL_0674|M.ulcerans_Agy99 LADRAGSFPGQLSGGQQQRVAIARALITNPDLLLADEPMGALDVATGRRV
MAV_4425|M.avium_104 LGNRTEHRPAELSGGQMQRVAVARALMMDPPLILADEPTGNLDSSTGAAI
TH_4101|M.thermoresistible__bu LADKARRVPAELSGGEQQRVAIARALFMRPDVILADEPTGNLDTKNGRIV
MLBr_00669|M.leprae_Br4923 LSGKANRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDI
: : * :***: **.* :*:: * ::***** . ** .. :
Mb1012|M.bovis_AF2122/97 LDVLLDLTRQAGKT--LIMATHSPSMTQHA-DRVVNLQGGRLIPALNREN
Rv0986|M.tuberculosis_H37Rv LDVLLDLTRQAGKT--LIMATHSPSMTQHA-DRVVNLQGGRLIPAVNREN
Mflv_4127|M.gilvum_PYR-GCK VRMLRDLCSTMGVT--VVASTHDPTVADEA-SRVVRMKDGQIVN------
Mvan_2216|M.vanbaalenii_PYR-1 VRMLRDLCSTMGVT--VVASTHDPTVADEA-SRVVRMKDGQIVN------
MSMEG_2524|M.smegmatis_MC2_155 VRMLRDLCLTLGVT--VVASTHDPTVADEA-SRVVRMRDGQIIN------
MAB_4671c|M.abscessus_ATCC_199 AAQLADAARSQGAA--VVIVTHDLRLTDIA-DRVLHLEDGVLLEKENQ--
MMAR_0922|M.marinum_M LELLQQTNRSGLG---VIMVTHNRAAADVA-DRIIQMRDGAIVEQRRNSA
MUL_0674|M.ulcerans_Agy99 LELLQQTNRSGLG---VIMVTHNRAAADVA-DPIIQMRDGAIVEQRRNSA
MAV_4425|M.avium_104 LELLAEVAHEGGGDRLVVMVTHNSDAAAAT-DRVITLQDGRVG----SDV
TH_4101|M.thermoresistible__bu LDTLKKLN-AAGQT--IVMVTHDLSIAEEA-PRLIAFRDGRIESDSAVPA
MLBr_00669|M.leprae_Br4923 MDLLERINRTGTT---VLMATHDHHIVDSMRQRVVELSLGRLVRDEWCGI
* :: **. . :: : * :
Mb1012|M.bovis_AF2122/97 QTDQPASTILLPTSYE--------
Rv0986|M.tuberculosis_H37Rv QTDQPASTILLPTSYE--------
Mflv_4127|M.gilvum_PYR-GCK ------------------------
Mvan_2216|M.vanbaalenii_PYR-1 ------------------------
MSMEG_2524|M.smegmatis_MC2_155 ------------------------
MAB_4671c|M.abscessus_ATCC_199 ------------------------
MMAR_0922|M.marinum_M PAEASSVRW---------------
MUL_0674|M.ulcerans_Agy99 PAEASSVRW---------------
MAV_4425|M.avium_104 LAVAG-------------------
TH_4101|M.thermoresistible__bu SGAAAETQSAEPDGVVVMLRKTGR
MLBr_00669|M.leprae_Br4923 YGMDR-------------------