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KGEAGVQPKLFIFPHAGGTPQYYVPFAKTFSTDIKRTAVQYPRQGGKQDFGSFTSLPDVADEIVKMVSPH ADGGVNGPPVFFFGHSMGGLLAFEVARRFEDAGRPISALFVSAVAAPGLVGYDDIPDTDEGLLAAVTTIT GADPEFMKNPEFAAAILPTLRGLKAIANYTCPPDVTLSCPIHAYYGDDDEIATADKVMPWAGRTSAGFTA RDFKGHHFYLNDHLDDVVPDIEQKVWSSLRE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3397 | - | - | 100% (242) | thioesterase |
| M. gilvum PYR-GCK | Mflv_1276 | - | 6e-30 | 33.48% (227) | thioesterase |
| M. gilvum PYR-GCK | Mflv_2693 | - | 3e-24 | 30.18% (222) | thioesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2953 | tesA | 2e-61 | 50.88% (228) | thioesterase TESA |
| M. tuberculosis H37Rv | Rv2928 | tesA | 2e-61 | 50.88% (228) | thioesterase TESA |
| M. leprae Br4923 | MLBr_02359 | - | 1e-62 | 50.42% (236) | thioesterase |
| M. abscessus ATCC 19977 | MAB_2033 | - | 1e-30 | 35.27% (224) | thioesterase |
| M. marinum M | MMAR_1778 | tesA | 2e-58 | 50.00% (226) | thioesterase TesA |
| M. avium 104 | MAV_2010 | - | 4e-27 | 31.98% (222) | phenyloxazoline synthase mbtb |
| M. smegmatis MC2 155 | MSMEG_4514 | - | 1e-28 | 32.02% (228) | thioesterase domain-containing protein |
| M. thermoresistible (build 8) | TH_4495 | - | 1e-30 | 36.07% (219) | PUTATIVE Thioesterase |
| M. ulcerans Agy99 | MUL_2025 | tesA | 1e-58 | 50.00% (226) | thioesterase TesA |
| M. vanbaalenii PYR-1 | Mvan_3130 | - | 1e-117 | 83.40% (235) | thioesterase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4514|M.smegmatis_MC2_155 -----MTGTEVSLESWIKRYPAENTASG-PTLVFPHAGGAALAYRPFALA
TH_4495|M.thermoresistible__bu -----MTVLRQDFAPWIKRFPAGGERTGRAAVLFPHAGGAAAAYRTLAKA
MAV_2010|M.avium_104 --------------------------------MFPHAGAAAASYRVLAAA
MAB_2033|M.abscessus_ATCC_1997 ---MRRTDELLPGNPWLRRLRDGNGATR--VICFPHAGGSASYFRRLAKM
Mflv_3397|M.gilvum_PYR-GCK ----------------MKGEAG----VQPKLFIFPHAGGTPQYYVPFAKT
Mvan_3130|M.vanbaalenii_PYR-1 ---------------MTTGGAGESSAGQPKLFIFPHAGGSAQYYVPFAKT
Mb2953|M.bovis_AF2122/97 MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
Rv2928|M.tuberculosis_H37Rv MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
MLBr_02359|M.leprae_Br4923 MLHVLRPGYAGAVNGHSNNGNDDETSTTPTLYIFPHAGGDATYYVPFSRE
MMAR_1778|M.marinum_M ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE
MUL_2025|M.ulcerans_Agy99 ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE
*****. . : ::
MSMEG_4514|M.smegmatis_MC2_155 LAEAGSDAYVMQYPRRGDRLSHPAPATVGDLARDLFEAGDWTRLG-----
TH_4495|M.thermoresistible__bu LSDNGTDTYIVQYPQRAERLRHPAADSISDLAAQLFEAGPWGSVG-----
MAV_2010|M.avium_104 LA-AGADTYVVQYPQRAERLGDPAHESVHDLAVGLFRAAPWPGVA-----
MAB_2033|M.abscessus_ATCC_1997 LP-ADTEVLAVQYPGRGNRLREQPIASVPLLAEGIASALPASDK------
Mflv_3397|M.gilvum_PYR-GCK FS-TDIKRTAVQYPRQGGKQDFGSFTSLPDVADEIVKMVSPHADGGVNGP
Mvan_3130|M.vanbaalenii_PYR-1 FA-TDIKRVAVQYPGQRGKQDFASFTSLPALADEVCKMVSPDKEGGVHGP
Mb2953|M.bovis_AF2122/97 FS-ADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSAR---IDD
Rv2928|M.tuberculosis_H37Rv FS-ADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSAR---IDD
MLBr_02359|M.leprae_Br4923 FS-ADIKRIAVHYPGQRDGYGLPALTSIPALADEIFAIMKPSAP---PEG
MMAR_1778|M.marinum_M FS-GEVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAAR---IDT
MUL_2025|M.ulcerans_Agy99 FS-GEVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAAR---IDT
:. . ::** : . :: :* :
MSMEG_4514|M.smegmatis_MC2_155 PLCLFGHCMGAVVAFEFARVAERNGVAVEALWVSASEAPSAVAASPALPM
TH_4495|M.thermoresistible__bu PLDLFGHCMGAVVAFEFARVAERHAVPVGTLWASAGQAPSTVGEGPPLPT
MAV_2010|M.avium_104 PLTLFGHSMGGVVAFEFARVAEANGTPVRKLWVSAGPPPCVVGDMPELPT
MAB_2033|M.abscessus_ATCC_1997 QDVLFGHSLGGHIAFEVA-----QRLPVRKLVVSGIVAPSKVVDLGYRLL
Mflv_3397|M.gilvum_PYR-GCK PVFFFGHSMGGLLAFEVARRFEDAGRPISALFVSAVAAPGLVGYDDIPD-
Mvan_3130|M.vanbaalenii_PYR-1 PIAFFGHSMGGLLAFEVARRFEEAGRPIAALFVSAVAAPGRVGYEDIPD-
Mb2953|M.bovis_AF2122/97 PVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDL
Rv2928|M.tuberculosis_H37Rv PVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDL
MLBr_02359|M.leprae_Br4923 AVAFFGHSMGGMLAFEVALRFQSAGYRLIALFVSACSAPGYIRYKQIKDF
MMAR_1778|M.marinum_M PVALFGHSMGGMLAFEVALRFEAAGYRVLALFLSACSAPGHIKYKQLKGY
MUL_2025|M.ulcerans_Agy99 PVALFGHSMGGMLAFEVALRFEAAGYRVLALFLSACSAPGHIKYKQLKGY
:***.:*. :***.* : : *. .* :
MSMEG_4514|M.smegmatis_MC2_155 GESEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEAFNRYSCDQGVT
TH_4495|M.thermoresistible__bu TDADVLADMVDLGGTDPRLLDDEDFVELLVMAVRADYRALSGYRCGPDER
MAV_2010|M.avium_104 THDGLLADIADLGGTDPELLADEEFSELLTTAVRADYQAFNGYDPSPDVR
MAB_2033|M.abscessus_ATCC_1997 NEAEGIERIAALGGLPPEILDDPSALSALFPVLRSDFTAGETYTPPPDAT
Mflv_3397|M.gilvum_PYR-GCK TDEGLLAAVTTITGADPEFMKNPEFAAAILPTLR-GLKAIANYTCPPDVT
Mvan_3130|M.vanbaalenii_PYR-1 DDEGLLAAVSSMTGANPEFMKNPEFAAAILPTLR-GLKAIANYTCPPDVT
Mb2953|M.bovis_AF2122/97 SDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETK
Rv2928|M.tuberculosis_H37Rv SDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETK
MLBr_02359|M.leprae_Br4923 SDNDMLDLVVRMTGMNPDFFEDEEFRVGVLPTLR-AARIIAGYNCPPETT
MMAR_1778|M.marinum_M SDNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENK
MUL_2025|M.ulcerans_Agy99 SDNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENK
. : . * * :: : . .:* *
MSMEG_4514|M.smegmatis_MC2_155 IAADIHALGGEQDHRISEDMLRGWQIHTEGAFTLSMFDGG-HFYINDYTD
TH_4495|M.thermoresistible__bu IRADIHALRGDRDHRISREWSDRWASHTSGRFTLSTFDGG-HFYLNDHLT
MAV_2010|M.avium_104 IGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGG-HFYLYDHVE
MAB_2033|M.abscessus_ATCC_1997 VACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHID
Mflv_3397|M.gilvum_PYR-GCK LSCPIHAYYGDDDEIATADKVMPWAGRTSAGFTARDFKGH-HFYLNDHLD
Mvan_3130|M.vanbaalenii_PYR-1 LSCPIHAFYGDDDEIATADKVKPWAERTTADFTAREFSGH-HFYLNDHLG
Mb2953|M.bovis_AF2122/97 LSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLNDNLP
Rv2928|M.tuberculosis_H37Rv LSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLNDNLP
MLBr_02359|M.leprae_Br4923 VSCPIYTYIGDKDWIATQEDMKPWRERTTGAFAIRVFPGD-HFYLNGNLS
MMAR_1778|M.marinum_M LSCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGD-HFYLNKNLP
MUL_2025|M.ulcerans_Agy99 LSCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGD-HFYLNKNLP
: . * . * * . * :* * : * ***:
MSMEG_4514|M.smegmatis_MC2_155 DVAELVNELW-------
TH_4495|M.thermoresistible__bu DVAALVSGR--------
MAV_2010|M.avium_104 TVAAQVNAG--------
MAB_2033|M.abscessus_ATCC_1997 EVSACLIQVCNVSPII-
Mflv_3397|M.gilvum_PYR-GCK DVVPDIEQKVWSSLRE-
Mvan_3130|M.vanbaalenii_PYR-1 ELVPDLEQKLWSRLRE-
Mb2953|M.bovis_AF2122/97 ELVSDIEDKTLQWHDRA
Rv2928|M.tuberculosis_H37Rv ELVSDIEDKTLQWHDRA
MLBr_02359|M.leprae_Br4923 ELVCDIEDKTLEWCDRA
MMAR_1778|M.marinum_M ELVSDIEIGTLQQFDQI
MUL_2025|M.ulcerans_Agy99 ELVSDIEIGTLQQFDQI
: :