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M. abscessus ATCC 19977 MAB_2033 (-)

annotation: thioesterase
coordinates: 2032838 - 2033587
length: 249

VRRTDELLPGNPWLRRLRDGNGATRVICFPHAGGSASYFRRLAKMLPADTEVLAVQYPGRGNRLREQPIA
SVPLLAEGIASALPASDKQDVLFGHSLGGHIAFEVAQRLPVRKLVVSGIVAPSKVVDLGYRLLNEAEGIE
RIAALGGLPPEILDDPSALSALFPVLRSDFTAGETYTPPPDATVACDITALIGDKDVLAPLERVSSWREH
TRANFDLQVFRGGGHFYLEDHIDEVSACLIQVCNVSPII
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2033--100% (249)thioesterase
M. abscessus ATCC 19977MAB_2121c-3e-2428.87% (239) putative phenyloxazoline synthase MbtB/ thioesterase
M. abscessus ATCC 19977MAB_2256-2e-2334.53% (223) polyketide synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2404cmbtB1e-3135.78% (232) phenyloxazoline synthase MBTB (phenyloxazoline synthetase)
M. gilvum PYR-GCKMflv_3397-2e-3035.27% (224) thioesterase
M. tuberculosis H37RvRv2383cmbtB1e-3135.78% (232) phenyloxazoline synthase MBTB (phenyloxazoline synthetase)
M. leprae Br4923MLBr_02359-5e-2833.80% (216) thioesterase
M. marinum MMMAR_3693-2e-2833.19% (238) thioesterase
M. avium 104MAV_2010-9e-3038.14% (215) phenyloxazoline synthase mbtb
M. smegmatis MC2 155MSMEG_4514-4e-2735.34% (232) thioesterase domain-containing protein
M. thermoresistible (build 8)TH_4495-1e-3137.87% (235) PUTATIVE Thioesterase
M. ulcerans Agy99MUL_3636-1e-2732.77% (238) thioesterase
M. vanbaalenii PYR-1Mvan_3130-2e-3437.28% (228) thioesterase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2404c|M.bovis_AF2122/97           MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWR
Rv2383c|M.tuberculosis_H37Rv        MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWR
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           RKGIAVDFATLAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPF
Rv2383c|M.tuberculosis_H37Rv        RKGIAVDFATLAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPF
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           PLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALR
Rv2383c|M.tuberculosis_H37Rv        PLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALR
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           HPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDA
Rv2383c|M.tuberculosis_H37Rv        HPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDA
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           KSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALY
Rv2383c|M.tuberculosis_H37Rv        KSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALY
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           DGREPPALGYTYQEYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL
Rv2383c|M.tuberculosis_H37Rv        DGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANV
Rv2383c|M.tuberculosis_H37Rv        PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANV
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           LARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAA
Rv2383c|M.tuberculosis_H37Rv        LARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAA
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           ARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGD
Rv2383c|M.tuberculosis_H37Rv        ARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGD
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           LFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPG
Rv2383c|M.tuberculosis_H37Rv        LFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPG
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           VIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPS
Rv2383c|M.tuberculosis_H37Rv        VIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPS
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           TEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR
Rv2383c|M.tuberculosis_H37Rv        TEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSV
Rv2383c|M.tuberculosis_H37Rv        VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSV
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           NLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSG
Rv2383c|M.tuberculosis_H37Rv        NLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSG
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           STGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIF
Rv2383c|M.tuberculosis_H37Rv        STGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIF
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           AALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGG
Rv2383c|M.tuberculosis_H37Rv        AALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGG
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           GRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFE
Rv2383c|M.tuberculosis_H37Rv        GRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFE
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           VQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI
Rv2383c|M.tuberculosis_H37Rv        VQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKI
Rv2383c|M.tuberculosis_H37Rv        ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKI
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           SGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAES
Rv2383c|M.tuberculosis_H37Rv        SGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAES
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           IRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGD
Rv2383c|M.tuberculosis_H37Rv        IRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGD
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           RSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQV
Rv2383c|M.tuberculosis_H37Rv        RSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQV
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           VAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLE
Rv2383c|M.tuberculosis_H37Rv        VAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLE
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2033|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_3397|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3130|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2404c|M.bovis_AF2122/97           IANMTSADVMAALDPIEQPAQPAFKPWVKRF-TGTDKPG-AVLVFPHAGG
Rv2383c|M.tuberculosis_H37Rv        IANMTSADVMAALDPIEQPAQPAFKPWVKRF-TGTDKPG-AVLVFPHAGG
TH_4495|M.thermoresistible__bu      ---------MTVLR-------QDFAPWIKRFPAGGERTGRAAVLFPHAGG
MAV_2010|M.avium_104                -------------------------------------------MFPHAGA
MSMEG_4514|M.smegmatis_MC2_155      ----------------MTGTEVSLESWIKRYPAENTASG-PTLVFPHAGG
MMAR_3693|M.marinum_M               --------------------MARKLGWVRQFHEPDAPESLPLLVFPHAGA
MUL_3636|M.ulcerans_Agy99           --------------------MARKLGWVRQFHEPDAPESLPLLVFPHAGA
MAB_2033|M.abscessus_ATCC_1997      --------------MRRTDELLPGNPWLRRLRDGNGATR--VICFPHAGG
Mflv_3397|M.gilvum_PYR-GCK          ----------------MKGEAG---------------VQPKLFIFPHAGG
Mvan_3130|M.vanbaalenii_PYR-1       ---------------MTTGGAGES-----------SAGQPKLFIFPHAGG
MLBr_02359|M.leprae_Br4923          -----------MLHVLRPGYAGAVNGHSNNGNDDETSTTPTLYIFPHAGG
                                                                                *****.

Mb2404c|M.bovis_AF2122/97           AAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELF---
Rv2383c|M.tuberculosis_H37Rv        AAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELF---
TH_4495|M.thermoresistible__bu      AAAAYRTLAKALSDNGTDTYIVQYPQRAERLRHPAADSISDLAAQLF---
MAV_2010|M.avium_104                AAASYRVLAAALAAG-ADTYVVQYPQRAERLGDPAHESVHDLAVGLF---
MSMEG_4514|M.smegmatis_MC2_155      AALAYRPFALALAEAGSDAYVMQYPRRGDRLSHPAPATVGDLARDLF---
MMAR_3693|M.marinum_M               GASAYREFSKVLSET-FNVIVFQYPGRQDRAAEPSCAAISEIAAGAFSEF
MUL_3636|M.ulcerans_Agy99           GASAYREFSKVLSET-FNVIVFQYPGRQDRAAEPSCAAISEIAAGAFSEF
MAB_2033|M.abscessus_ATCC_1997      SASYFRRLAKMLPAD-TEVLAVQYPGRGNRLREQPIASVPLLAEGIASAL
Mflv_3397|M.gilvum_PYR-GCK          TPQYYVPFAKTFSTD-IKRTAVQYPRQGGKQDFGSFTSLPDVADEIVKMV
Mvan_3130|M.vanbaalenii_PYR-1       SAQYYVPFAKTFATD-IKRVAVQYPGQRGKQDFASFTSLPALADEVCKMV
MLBr_02359|M.leprae_Br4923          DATYYVPFSREFSAD-IKRIAVHYPGQRDGYGLPALTSIPALADEIFAIM
                                     .  :  ::  :     .   .:** :       .  ::  :*       

Mb2404c|M.bovis_AF2122/97           --EAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAP
Rv2383c|M.tuberculosis_H37Rv        --EAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAP
TH_4495|M.thermoresistible__bu      --EAGPWGSVGPLDLFGHCMGAVVAFEFARVAERHAVPVGTLWASAGQAP
MAV_2010|M.avium_104                --RAAPWPGVAPLTLFGHSMGGVVAFEFARVAEANGTPVRKLWVSAGPPP
MSMEG_4514|M.smegmatis_MC2_155      --EAGDWTRLGPLCLFGHCMGAVVAFEFARVAERNGVAVEALWVSASEAP
MMAR_3693|M.marinum_M               --AASEHNRGLPIITFGHSMGALVAFEFVRLAEANGIDVRHLNVSAAVAP
MUL_3636|M.ulcerans_Agy99           --AASEHNRGLPIITFGHSMGALVAFEFVRLAEANGIDVRHLNVSAAVAP
MAB_2033|M.abscessus_ATCC_1997      --PASDKQD----VLFGHSLGGHIAFEVA-----QRLPVRKLVVSGIVAP
Mflv_3397|M.gilvum_PYR-GCK          SPHADGGVNGPPVFFFGHSMGGLLAFEVARRFEDAGRPISALFVSAVAAP
Mvan_3130|M.vanbaalenii_PYR-1       SPDKEGGVHGPPIAFFGHSMGGLLAFEVARRFEEAGRPIAALFVSAVAAP
MLBr_02359|M.leprae_Br4923          KPSAP--PEG-AVAFFGHSMGGMLAFEVALRFQSAGYRLIALFVSACSAP
                                                   ***.:*. :***..         :  * .*.  .*

Mb2404c|M.bovis_AF2122/97           STVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRA
Rv2383c|M.tuberculosis_H37Rv        STVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRA
TH_4495|M.thermoresistible__bu      STVGEGPPLPTTDADVLADMVDLGGTDPRLLDDEDFVELLVMAVRADYRA
MAV_2010|M.avium_104                CVVGDMPELPTTHDGLLADIADLGGTDPELLADEEFSELLTTAVRADYQA
MSMEG_4514|M.smegmatis_MC2_155      SAVAASPALPMGESEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEA
MMAR_3693|M.marinum_M               CNAAAKPAHPSDDEEILNHLGALEGTDTDVFSNRELMRLALPVIKADYHA
MUL_3636|M.ulcerans_Agy99           CNAAAKPAHPSDDEEILNHLGALEGTDTDVFSNRELMRLALRVIKADYHA
MAB_2033|M.abscessus_ATCC_1997      SKVVDLGYRLLNEAEGIERIAALGGLPPEILDDPSALSALFPVLRSDFTA
Mflv_3397|M.gilvum_PYR-GCK          GLVGYDDIPD-TDEGLLAAVTTITGADPEFMKNPEFAAAILPTLRG-LKA
Mvan_3130|M.vanbaalenii_PYR-1       GRVGYEDIPD-DDEGLLAAVSSMTGANPEFMKNPEFAAAILPTLRG-LKA
MLBr_02359|M.leprae_Br4923          GYIRYKQIKDFSDNDMLDLVVRMTGMNPDFFEDEEFRVGVLPTLRA-ARI
                                                .   :  :  : *  . .: : .       .::.    

Mb2404c|M.bovis_AF2122/97           LSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDG
Rv2383c|M.tuberculosis_H37Rv        LSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDG
TH_4495|M.thermoresistible__bu      LSGYRCGPDERIRADIHALRGDRDHRISREWSDRWASHTSGRFTLSTFDG
MAV_2010|M.avium_104                FNGYDPSPDVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDG
MSMEG_4514|M.smegmatis_MC2_155      FNRYSCDQGVTIAADIHALGGEQDHRISEDMLRGWQIHTEGAFTLSMFDG
MMAR_3693|M.marinum_M               FDTYSCAEDIKVATPIHAMGGDQDPYITLGDLYGWGKHTD-TAKVTMFDG
MUL_3636|M.ulcerans_Agy99           FDTYSCAEDIKVATPIHAMGGDQDPYITLGDLYGWGKHTD-TAKVTMFDG
MAB_2033|M.abscessus_ATCC_1997      GETYTPPPDATVACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRG
Mflv_3397|M.gilvum_PYR-GCK          IANYTCPPDVTLSCPIHAYYGDDDEIATADKVMPWAGRTSAGFTARDFKG
Mvan_3130|M.vanbaalenii_PYR-1       IANYTCPPDVTLSCPIHAFYGDDDEIATADKVKPWAERTTADFTAREFSG
MLBr_02359|M.leprae_Br4923          IAGYNCPPETTVSCPIYTYIGDKDWIATQEDMKPWRERTTGAFAIRVFPG
                                       *       :   * .  *. *   .      *  :*        : *

Mb2404c|M.bovis_AF2122/97           G-HFYLNDHLDAVARMVSADVR------
Rv2383c|M.tuberculosis_H37Rv        G-HFYLNDHLDAVARMVSADVR------
TH_4495|M.thermoresistible__bu      G-HFYLNDHLTDVAALVSGR--------
MAV_2010|M.avium_104                G-HFYLYDHVETVAAQVNAG--------
MSMEG_4514|M.smegmatis_MC2_155      G-HFYINDYTDDVAELVNELW-------
MMAR_3693|M.marinum_M               G-HFYLRSHIDAVAALLASSAQCGQQA-
MUL_3636|M.ulcerans_Agy99           G-HFYLRSHIDAVAALLASSAQCGQQA-
MAB_2033|M.abscessus_ATCC_1997      GGHFYLEDHIDEVSACLIQVCNVSPII-
Mflv_3397|M.gilvum_PYR-GCK          H-HFYLNDHLDDVVPDIEQKVWSSLRE-
Mvan_3130|M.vanbaalenii_PYR-1       H-HFYLNDHLGELVPDLEQKLWSRLRE-
MLBr_02359|M.leprae_Br4923          D-HFYLNGNLSELVCDIEDKTLEWCDRA
                                      ***: .    :   :