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VTQPPRSRWLRNFHPAPSARTRLVCLPHAGGSASYYFPMSAALSPEFNVYGVQYPGRQDRHSEPFVESVD DLADQIYAEVAALPEVPTAFFGHSMGAVLAFEVARRFESLAGRRPVVVFASGSRAPSHYGDEREYKSDND LIGVMRDLGGTDPRIFNDPDLLSTFLPAFRNDYRALQAYHRGTEVVISAPIVVMTATDDPKTSEDNARAW LAHTTGGGEVRTFTGGHFYLEKQPQKVIEVVTQTLRDVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1276 | - | - | 100% (249) | thioesterase |
| M. gilvum PYR-GCK | Mflv_3397 | - | 6e-30 | 33.48% (227) | thioesterase |
| M. gilvum PYR-GCK | Mflv_2693 | - | 6e-29 | 33.19% (235) | thioesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2953 | tesA | 7e-33 | 36.17% (235) | thioesterase TESA |
| M. tuberculosis H37Rv | Rv2928 | tesA | 8e-33 | 36.17% (235) | thioesterase TESA |
| M. leprae Br4923 | MLBr_02359 | - | 8e-35 | 37.79% (217) | thioesterase |
| M. abscessus ATCC 19977 | MAB_2121c | - | 3e-32 | 35.71% (238) | putative phenyloxazoline synthase MbtB/ thioesterase |
| M. marinum M | MMAR_1778 | tesA | 3e-36 | 39.74% (229) | thioesterase TesA |
| M. avium 104 | MAV_2010 | - | 3e-29 | 37.86% (206) | phenyloxazoline synthase mbtb |
| M. smegmatis MC2 155 | MSMEG_4514 | - | 7e-33 | 36.03% (247) | thioesterase domain-containing protein |
| M. thermoresistible (build 8) | TH_4495 | - | 5e-35 | 39.33% (239) | PUTATIVE Thioesterase |
| M. ulcerans Agy99 | MUL_2025 | tesA | 2e-36 | 39.74% (229) | thioesterase TesA |
| M. vanbaalenii PYR-1 | Mvan_5540 | - | 1e-117 | 77.91% (249) | thioesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1276|M.gilvum_PYR-GCK -------MTQPPRSRWLRNFHP-APSARTRLVCLPHAGGSASYYFPMSAA
Mvan_5540|M.vanbaalenii_PYR-1 -------MTQPQRSRWMRNFHP-SPTARIRLVCFPHAGGSASYYFPLSSA
MAV_2010|M.avium_104 --------------------------------MFPHAGAAAASYRVLAAA
TH_4495|M.thermoresistible__bu -----MTVLRQDFAPWIKRFPAGGERTGRAAVLFPHAGGAAAAYRTLAKA
MSMEG_4514|M.smegmatis_MC2_155 -----MTGTEVSLESWIKRYPAENTASG-PTLVFPHAGGAALAYRPFALA
MAB_2121c|M.abscessus_ATCC_199 --------MDRKLG-WIRQFHKPESPDAPLLLIFPHAGAGASAYRTLSKA
Mb2953|M.bovis_AF2122/97 MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
Rv2928|M.tuberculosis_H37Rv MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
MLBr_02359|M.leprae_Br4923 MLHVLRPGYAGAVNGHSNNGNDDETSTTPTLYIFPHAGGDATYYVPFSRE
MMAR_1778|M.marinum_M ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE
MUL_2025|M.ulcerans_Agy99 ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE
:****. * * ::
Mflv_1276|M.gilvum_PYR-GCK LSP-EFNVYGVQYPGRQDRHSEPFVESVDDLAD---QIYAEVAALPEVPT
Mvan_5540|M.vanbaalenii_PYR-1 LTP-EFDVFGVQYPGRQDRYSEPFVETIDELAD---QAHAALSALPDAPL
MAV_2010|M.avium_104 LAA-GADTYVVQYPQRAERLGDPAHESVHDLAV---GLFRAAPWPGVAPL
TH_4495|M.thermoresistible__bu LSDNGTDTYIVQYPQRAERLRHPAADSISDLAA---QLFEAGPWGSVGPL
MSMEG_4514|M.smegmatis_MC2_155 LAEAGSDAYVMQYPRRGDRLSHPAPATVGDLAR---DLFEAGDWTRLGPL
MAB_2121c|M.abscessus_ATCC_199 SSA-NFNVLVFQYPGRQDRAGEPALPTLSDIAAGAFAEFQSSEHNRRVPI
Mb2953|M.bovis_AF2122/97 FSA-DVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSARI-DDPV
Rv2928|M.tuberculosis_H37Rv FSA-DVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSARI-DDPV
MLBr_02359|M.leprae_Br4923 FSA-DIKRIAVHYPGQRDGYGLPALTSIPALADEIFAIMKPSAPP-EGAV
MMAR_1778|M.marinum_M FSG-EVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAARI-DTPV
MUL_2025|M.ulcerans_Agy99 FSG-EVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAARI-DTPV
: . .:** : : * :: :* .
Mflv_1276|M.gilvum_PYR-GCK AFFGHSMGAVLAFEVARRFESLAGRRPVVVFASGSRAPSHYGDEREYKS-
Mvan_5540|M.vanbaalenii_PYR-1 AFFGHSMGAVLAFEVARRCETLSGRQVVTVFASGSRAPSRYGDERNAKS-
MAV_2010|M.avium_104 TLFGHSMGGVVAFEFARVAEAN-GTPVRKLWVSAGPPPCVVGDMPELPTT
TH_4495|M.thermoresistible__bu DLFGHCMGAVVAFEFARVAERH-AVPVGTLWASAGQAPSTVGEGPPLPTT
MSMEG_4514|M.smegmatis_MC2_155 CLFGHCMGAVVAFEFARVAERN-GVAVEALWVSASEAPSAVAASPALPMG
MAB_2121c|M.abscessus_ATCC_199 HTFGHSMGAVVSFEFARLAEAA-GLDVHQLTVSSAVAPCNIADKPALPTD
Mb2953|M.bovis_AF2122/97 AFFGHSMGGMLAFEVALRYQSA-GHRVLAFFVSACSAPGHIRYKQLQDLS
Rv2928|M.tuberculosis_H37Rv AFFGHSMGGMLAFEVALRYQSA-GHRVLAFFVSACSAPGHIRYKQLQDLS
MLBr_02359|M.leprae_Br4923 AFFGHSMGGMLAFEVALRFQSA-GYRLIALFVSACSAPGYIRYKQIKDFS
MMAR_1778|M.marinum_M ALFGHSMGGMLAFEVALRFEAA-GYRVLALFLSACSAPGHIKYKQLKGYS
MUL_2025|M.ulcerans_Agy99 ALFGHSMGGMLAFEVALRFEAA-GYRVLALFLSACSAPGHIKYKQLKGYS
***.**.:::**.* : . . *. .*
Mflv_1276|M.gilvum_PYR-GCK DNDLIGVMRDLGGTDPRIFNDPDLLSTFLPAFRNDYRALQAYHRGTEVVI
Mvan_5540|M.vanbaalenii_PYR-1 DTDLVGVMRELGGTDPRVLENPELLATFLPAFRNDYRALQAYHRGTDIGI
MAV_2010|M.avium_104 HDGLLADIADLGGTDPELLADEEFSELLTTAVRADYQAFNGYDPSPDVRI
TH_4495|M.thermoresistible__bu DADVLADMVDLGGTDPRLLDDEDFVELLVMAVRADYRALSGYRCGPDERI
MSMEG_4514|M.smegmatis_MC2_155 ESEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEAFNRYSCDQGVTI
MAB_2121c|M.abscessus_ATCC_199 DDAVLAHMGALEGTNSTVMGNLDVMRMALPVMKGDYQAFNAYQCADGAKV
Mb2953|M.bovis_AF2122/97 DREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETKL
Rv2928|M.tuberculosis_H37Rv DREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETKL
MLBr_02359|M.leprae_Br4923 DNDMLDLVVRMTGMNPDFFEDEEFRVGVLPTLR-AARIIAGYNCPPETTV
MMAR_1778|M.marinum_M DNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENKL
MUL_2025|M.ulcerans_Agy99 DNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENKL
. :: . * :. .: : :. ..: . : * :
Mflv_1276|M.gilvum_PYR-GCK SAPIVVMTATDDPKTSEDNARAWLAHTTGGGEVRTFTGGHFYLEKQPQKV
Mvan_5540|M.vanbaalenii_PYR-1 SAPIVVMTATDDPKTSETDARAWHEHTSGGGEVHTFTGGHFYLEKQPQRV
MAV_2010|M.avium_104 GADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGGHFYLYDHVETV
TH_4495|M.thermoresistible__bu RADIHALRGDRDHRISREWSDRWASHTSGRFTLSTFDGGHFYLNDHLTDV
MSMEG_4514|M.smegmatis_MC2_155 AADIHALGGEQDHRISEDMLRGWQIHTEGAFTLSMFDGGHFYINDYTDDV
MAB_2121c|M.abscessus_ATCC_199 AARIHSIGGDQDPMITMRDLYGWAQHTD-ALEVTLFDGGHFFLNSQTEAL
Mb2953|M.bovis_AF2122/97 SCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLNDNLPEL
Rv2928|M.tuberculosis_H37Rv SCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLNDNLPEL
MLBr_02359|M.leprae_Br4923 SCPIYTYIGDKDWIATQEDMKPWRERTTGAFAIRVFPGDHFYLNGNLSEL
MMAR_1778|M.marinum_M SCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGDHFYLNKNLPEL
MUL_2025|M.ulcerans_Agy99 SCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGDHFYLNKNLPEL
. * . * : * :* : : *.**:: :
Mflv_1276|M.gilvum_PYR-GCK IEVVTQTLRDVG----
Mvan_5540|M.vanbaalenii_PYR-1 IEVVSATLRSVG----
MAV_2010|M.avium_104 AAQVNAG---------
TH_4495|M.thermoresistible__bu AALVSGR---------
MSMEG_4514|M.smegmatis_MC2_155 AELVNELW--------
MAB_2121c|M.abscessus_ATCC_199 AELLVANSASASSPQR
Mb2953|M.bovis_AF2122/97 VSDIEDKTLQWHDRA-
Rv2928|M.tuberculosis_H37Rv VSDIEDKTLQWHDRA-
MLBr_02359|M.leprae_Br4923 VCDIEDKTLEWCDRA-
MMAR_1778|M.marinum_M VSDIEIGTLQQFDQI-
MUL_2025|M.ulcerans_Agy99 VSDIEIGTLQQFDQI-
: