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MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHDRSG LPPLESIPTLADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRY KQLQDLSDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLRAVRAIAGYSCPPETKLSCPIYAFIGDKDWI ATQDDMDPWRDRTTEEFSIRVFPGDHFYLNDNLPELVSDIEDKTLQWHDRA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2953 | tesA | - | 100% (261) | thioesterase TESA |
M. bovis AF2122 / 97 | Mb2404c | mbtB | 2e-30 | 34.74% (213) | phenyloxazoline synthase MBTB (phenyloxazoline synthetase) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3397 | - | 3e-61 | 50.88% (228) | thioesterase |
M. tuberculosis H37Rv | Rv2928 | tesA | 1e-155 | 100.00% (261) | thioesterase TESA |
M. leprae Br4923 | MLBr_02359 | - | 1e-112 | 74.12% (255) | thioesterase |
M. abscessus ATCC 19977 | MAB_2033 | - | 1e-29 | 34.39% (221) | thioesterase |
M. marinum M | MMAR_1778 | tesA | 1e-110 | 75.40% (248) | thioesterase TesA |
M. avium 104 | MAV_2010 | - | 6e-21 | 29.86% (221) | phenyloxazoline synthase mbtb |
M. smegmatis MC2 155 | MSMEG_4514 | - | 5e-24 | 31.00% (229) | thioesterase domain-containing protein |
M. thermoresistible (build 8) | TH_4495 | - | 8e-25 | 31.19% (218) | PUTATIVE Thioesterase |
M. ulcerans Agy99 | MUL_2025 | tesA | 1e-110 | 75.40% (248) | thioesterase TesA |
M. vanbaalenii PYR-1 | Mvan_3130 | - | 1e-67 | 50.85% (236) | thioesterase |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_4514|M.smegmatis_MC2_155 -----MTGTEVSLESWIKRYPAENTASG-PTLVFPHAGGAALAYRPFALA TH_4495|M.thermoresistible__bu -----MTVLRQDFAPWIKRFPAGGERTGRAAVLFPHAGGAAAAYRTLAKA MAV_2010|M.avium_104 --------------------------------MFPHAGAAAASYRVLAAA MAB_2033|M.abscessus_ATCC_1997 ---MRRTDELLPGNPWLRRLRDGNGATR--VICFPHAGGSASYFRRLAKM Mb2953|M.bovis_AF2122/97 MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE Rv2928|M.tuberculosis_H37Rv MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE MLBr_02359|M.leprae_Br4923 MLHVLRPGYAGAVNGHSNNGNDDETSTTPTLYIFPHAGGDATYYVPFSRE MMAR_1778|M.marinum_M ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE MUL_2025|M.ulcerans_Agy99 ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE Mflv_3397|M.gilvum_PYR-GCK ----------------MKGEAG----VQPKLFIFPHAGGTPQYYVPFAKT Mvan_3130|M.vanbaalenii_PYR-1 ---------------MTTGGAGESSAGQPKLFIFPHAGGSAQYYVPFAKT *****. . : :: MSMEG_4514|M.smegmatis_MC2_155 LAEAGSDAYVMQYPRRGDRLSHPAPATVGDLARDLFEAGDWTRLG----- TH_4495|M.thermoresistible__bu LSDNGTDTYIVQYPQRAERLRHPAADSISDLAAQLFEAGPWGSVG----- MAV_2010|M.avium_104 LA-AGADTYVVQYPQRAERLGDPAHESVHDLAVGLFRAAPWPGVA----- MAB_2033|M.abscessus_ATCC_1997 LP-ADTEVLAVQYPGRGNRLREQPIASVPLLAEGIASALPASDK------ Mb2953|M.bovis_AF2122/97 FS-ADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSAR---IDD Rv2928|M.tuberculosis_H37Rv FS-ADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSAR---IDD MLBr_02359|M.leprae_Br4923 FS-ADIKRIAVHYPGQRDGYGLPALTSIPALADEIFAIMKPSAP---PEG MMAR_1778|M.marinum_M FS-GEVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAAR---IDT MUL_2025|M.ulcerans_Agy99 FS-GEVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAAR---IDT Mflv_3397|M.gilvum_PYR-GCK FS-TDIKRTAVQYPRQGGKQDFGSFTSLPDVADEIVKMVSPHADGGVNGP Mvan_3130|M.vanbaalenii_PYR-1 FA-TDIKRVAVQYPGQRGKQDFASFTSLPALADEVCKMVSPDKEGGVHGP :. . ::** : . :: :* : MSMEG_4514|M.smegmatis_MC2_155 PLCLFGHCMGAVVAFEFARVAERNGVAVEALWVSASEAPSAVAASPALPM TH_4495|M.thermoresistible__bu PLDLFGHCMGAVVAFEFARVAERHAVPVGTLWASAGQAPSTVGEGPPLPT MAV_2010|M.avium_104 PLTLFGHSMGGVVAFEFARVAEANGTPVRKLWVSAGPPPCVVGDMPELPT MAB_2033|M.abscessus_ATCC_1997 QDVLFGHSLGGHIAFEVA-----QRLPVRKLVVSGIVAPSKVVDLGYRLL Mb2953|M.bovis_AF2122/97 PVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDL Rv2928|M.tuberculosis_H37Rv PVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDL MLBr_02359|M.leprae_Br4923 AVAFFGHSMGGMLAFEVALRFQSAGYRLIALFVSACSAPGYIRYKQIKDF MMAR_1778|M.marinum_M PVALFGHSMGGMLAFEVALRFEAAGYRVLALFLSACSAPGHIKYKQLKGY MUL_2025|M.ulcerans_Agy99 PVALFGHSMGGMLAFEVALRFEAAGYRVLALFLSACSAPGHIKYKQLKGY Mflv_3397|M.gilvum_PYR-GCK PVFFFGHSMGGLLAFEVARRFEDAGRPISALFVSAVAAPGLVGYDDIPD- Mvan_3130|M.vanbaalenii_PYR-1 PIAFFGHSMGGLLAFEVARRFEEAGRPIAALFVSAVAAPGRVGYEDIPD- :***.:*. :***.* : : *. .* : MSMEG_4514|M.smegmatis_MC2_155 GESEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEAFNRYSCDQGVT TH_4495|M.thermoresistible__bu TDADVLADMVDLGGTDPRLLDDEDFVELLVMAVRADYRALSGYRCGPDER MAV_2010|M.avium_104 THDGLLADIADLGGTDPELLADEEFSELLTTAVRADYQAFNGYDPSPDVR MAB_2033|M.abscessus_ATCC_1997 NEAEGIERIAALGGLPPEILDDPSALSALFPVLRSDFTAGETYTPPPDAT Mb2953|M.bovis_AF2122/97 SDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETK Rv2928|M.tuberculosis_H37Rv SDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETK MLBr_02359|M.leprae_Br4923 SDNDMLDLVVRMTGMNPDFFEDEEFRVGVLPTLR-AARIIAGYNCPPETT MMAR_1778|M.marinum_M SDNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENK MUL_2025|M.ulcerans_Agy99 SDNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENK Mflv_3397|M.gilvum_PYR-GCK TDEGLLAAVTTITGADPEFMKNPEFAAAILPTLR-GLKAIANYTCPPDVT Mvan_3130|M.vanbaalenii_PYR-1 DDEGLLAAVSSMTGANPEFMKNPEFAAAILPTLR-GLKAIANYTCPPDVT . : . * * :: : . .:* * MSMEG_4514|M.smegmatis_MC2_155 IAADIHALGGEQDHRISEDMLRGWQIHTEGAFTLSMFDGG-HFYINDYTD TH_4495|M.thermoresistible__bu IRADIHALRGDRDHRISREWSDRWASHTSGRFTLSTFDGG-HFYLNDHLT MAV_2010|M.avium_104 IGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGG-HFYLYDHVE MAB_2033|M.abscessus_ATCC_1997 VACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHID Mb2953|M.bovis_AF2122/97 LSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLNDNLP Rv2928|M.tuberculosis_H37Rv LSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLNDNLP MLBr_02359|M.leprae_Br4923 VSCPIYTYIGDKDWIATQEDMKPWRERTTGAFAIRVFPGD-HFYLNGNLS MMAR_1778|M.marinum_M LSCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGD-HFYLNKNLP MUL_2025|M.ulcerans_Agy99 LSCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGD-HFYLNKNLP Mflv_3397|M.gilvum_PYR-GCK LSCPIHAYYGDDDEIATADKVMPWAGRTSAGFTARDFKGH-HFYLNDHLD Mvan_3130|M.vanbaalenii_PYR-1 LSCPIHAFYGDDDEIATADKVKPWAERTTADFTAREFSGH-HFYLNDHLG : . * . * * . * :* * : * ***: MSMEG_4514|M.smegmatis_MC2_155 DVAELVNELW------- TH_4495|M.thermoresistible__bu DVAALVSGR-------- MAV_2010|M.avium_104 TVAAQVNAG-------- MAB_2033|M.abscessus_ATCC_1997 EVSACLIQVCNVSPII- Mb2953|M.bovis_AF2122/97 ELVSDIEDKTLQWHDRA Rv2928|M.tuberculosis_H37Rv ELVSDIEDKTLQWHDRA MLBr_02359|M.leprae_Br4923 ELVCDIEDKTLEWCDRA MMAR_1778|M.marinum_M ELVSDIEIGTLQQFDQI MUL_2025|M.ulcerans_Agy99 ELVSDIEIGTLQQFDQI Mflv_3397|M.gilvum_PYR-GCK DVVPDIEQKVWSSLRE- Mvan_3130|M.vanbaalenii_PYR-1 ELVPDLEQKLWSRLRE- : :