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M. bovis AF2122 / 97 Mb2953 (tesA)

annotation: thioesterase TESA
coordinates: 3198771 - 3199556
length: 261

MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHDRSG
LPPLESIPTLADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRY
KQLQDLSDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLRAVRAIAGYSCPPETKLSCPIYAFIGDKDWI
ATQDDMDPWRDRTTEEFSIRVFPGDHFYLNDNLPELVSDIEDKTLQWHDRA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2953tesA-100% (261)thioesterase TESA
M. bovis AF2122 / 97Mb2404cmbtB2e-3034.74% (213) phenyloxazoline synthase MBTB (phenyloxazoline synthetase)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3397-3e-6150.88% (228) thioesterase
M. tuberculosis H37RvRv2928tesA1e-155100.00% (261) thioesterase TESA
M. leprae Br4923MLBr_02359-1e-11274.12% (255) thioesterase
M. abscessus ATCC 19977MAB_2033-1e-2934.39% (221) thioesterase
M. marinum MMMAR_1778tesA1e-11075.40% (248) thioesterase TesA
M. avium 104MAV_2010-6e-2129.86% (221) phenyloxazoline synthase mbtb
M. smegmatis MC2 155MSMEG_4514-5e-2431.00% (229) thioesterase domain-containing protein
M. thermoresistible (build 8)TH_4495-8e-2531.19% (218) PUTATIVE Thioesterase
M. ulcerans Agy99MUL_2025tesA1e-11075.40% (248) thioesterase TesA
M. vanbaalenii PYR-1Mvan_3130-1e-6750.85% (236) thioesterase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4514|M.smegmatis_MC2_155      -----MTGTEVSLESWIKRYPAENTASG-PTLVFPHAGGAALAYRPFALA
TH_4495|M.thermoresistible__bu      -----MTVLRQDFAPWIKRFPAGGERTGRAAVLFPHAGGAAAAYRTLAKA
MAV_2010|M.avium_104                --------------------------------MFPHAGAAAASYRVLAAA
MAB_2033|M.abscessus_ATCC_1997      ---MRRTDELLPGNPWLRRLRDGNGATR--VICFPHAGGSASYFRRLAKM
Mb2953|M.bovis_AF2122/97            MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
Rv2928|M.tuberculosis_H37Rv         MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
MLBr_02359|M.leprae_Br4923          MLHVLRPGYAGAVNGHSNNGNDDETSTTPTLYIFPHAGGDATYYVPFSRE
MMAR_1778|M.marinum_M               ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE
MUL_2025|M.ulcerans_Agy99           ------------MNGRSSNSKSDEKLTAPTLYIFPHAGGTAKDYVPFAKE
Mflv_3397|M.gilvum_PYR-GCK          ----------------MKGEAG----VQPKLFIFPHAGGTPQYYVPFAKT
Mvan_3130|M.vanbaalenii_PYR-1       ---------------MTTGGAGESSAGQPKLFIFPHAGGSAQYYVPFAKT
                                                                     *****. .  :  ::  

MSMEG_4514|M.smegmatis_MC2_155      LAEAGSDAYVMQYPRRGDRLSHPAPATVGDLARDLFEAGDWTRLG-----
TH_4495|M.thermoresistible__bu      LSDNGTDTYIVQYPQRAERLRHPAADSISDLAAQLFEAGPWGSVG-----
MAV_2010|M.avium_104                LA-AGADTYVVQYPQRAERLGDPAHESVHDLAVGLFRAAPWPGVA-----
MAB_2033|M.abscessus_ATCC_1997      LP-ADTEVLAVQYPGRGNRLREQPIASVPLLAEGIASALPASDK------
Mb2953|M.bovis_AF2122/97            FS-ADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSAR---IDD
Rv2928|M.tuberculosis_H37Rv         FS-ADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSAR---IDD
MLBr_02359|M.leprae_Br4923          FS-ADIKRIAVHYPGQRDGYGLPALTSIPALADEIFAIMKPSAP---PEG
MMAR_1778|M.marinum_M               FS-GEVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAAR---IDT
MUL_2025|M.ulcerans_Agy99           FS-GEVKRVAVQYPGQQDGYGLPPLESIPGLAEEIFAIMKPAAR---IDT
Mflv_3397|M.gilvum_PYR-GCK          FS-TDIKRTAVQYPRQGGKQDFGSFTSLPDVADEIVKMVSPHADGGVNGP
Mvan_3130|M.vanbaalenii_PYR-1       FA-TDIKRVAVQYPGQRGKQDFASFTSLPALADEVCKMVSPDKEGGVHGP
                                    :.    .   ::** :       .  ::  :*  :               

MSMEG_4514|M.smegmatis_MC2_155      PLCLFGHCMGAVVAFEFARVAERNGVAVEALWVSASEAPSAVAASPALPM
TH_4495|M.thermoresistible__bu      PLDLFGHCMGAVVAFEFARVAERHAVPVGTLWASAGQAPSTVGEGPPLPT
MAV_2010|M.avium_104                PLTLFGHSMGGVVAFEFARVAEANGTPVRKLWVSAGPPPCVVGDMPELPT
MAB_2033|M.abscessus_ATCC_1997      QDVLFGHSLGGHIAFEVA-----QRLPVRKLVVSGIVAPSKVVDLGYRLL
Mb2953|M.bovis_AF2122/97            PVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDL
Rv2928|M.tuberculosis_H37Rv         PVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDL
MLBr_02359|M.leprae_Br4923          AVAFFGHSMGGMLAFEVALRFQSAGYRLIALFVSACSAPGYIRYKQIKDF
MMAR_1778|M.marinum_M               PVALFGHSMGGMLAFEVALRFEAAGYRVLALFLSACSAPGHIKYKQLKGY
MUL_2025|M.ulcerans_Agy99           PVALFGHSMGGMLAFEVALRFEAAGYRVLALFLSACSAPGHIKYKQLKGY
Mflv_3397|M.gilvum_PYR-GCK          PVFFFGHSMGGLLAFEVARRFEDAGRPISALFVSAVAAPGLVGYDDIPD-
Mvan_3130|M.vanbaalenii_PYR-1       PIAFFGHSMGGLLAFEVARRFEEAGRPIAALFVSAVAAPGRVGYEDIPD-
                                       :***.:*. :***.*         :  :  *.  .*  :        

MSMEG_4514|M.smegmatis_MC2_155      GESEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEAFNRYSCDQGVT
TH_4495|M.thermoresistible__bu      TDADVLADMVDLGGTDPRLLDDEDFVELLVMAVRADYRALSGYRCGPDER
MAV_2010|M.avium_104                THDGLLADIADLGGTDPELLADEEFSELLTTAVRADYQAFNGYDPSPDVR
MAB_2033|M.abscessus_ATCC_1997      NEAEGIERIAALGGLPPEILDDPSALSALFPVLRSDFTAGETYTPPPDAT
Mb2953|M.bovis_AF2122/97            SDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETK
Rv2928|M.tuberculosis_H37Rv         SDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR-AVRAIAGYSCPPETK
MLBr_02359|M.leprae_Br4923          SDNDMLDLVVRMTGMNPDFFEDEEFRVGVLPTLR-AARIIAGYNCPPETT
MMAR_1778|M.marinum_M               SDNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENK
MUL_2025|M.ulcerans_Agy99           SDNEMLDLVARATGTDPEFFNDEEFRVGVLPTLR-AVRAIAGYSCPPENK
Mflv_3397|M.gilvum_PYR-GCK          TDEGLLAAVTTITGADPEFMKNPEFAAAILPTLR-GLKAIANYTCPPDVT
Mvan_3130|M.vanbaalenii_PYR-1       DDEGLLAAVSSMTGANPEFMKNPEFAAAILPTLR-GLKAIANYTCPPDVT
                                     .   :  .    *  * :: : .       .:*        *       

MSMEG_4514|M.smegmatis_MC2_155      IAADIHALGGEQDHRISEDMLRGWQIHTEGAFTLSMFDGG-HFYINDYTD
TH_4495|M.thermoresistible__bu      IRADIHALRGDRDHRISREWSDRWASHTSGRFTLSTFDGG-HFYLNDHLT
MAV_2010|M.avium_104                IGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGG-HFYLYDHVE
MAB_2033|M.abscessus_ATCC_1997      VACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHID
Mb2953|M.bovis_AF2122/97            LSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLNDNLP
Rv2928|M.tuberculosis_H37Rv         LSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLNDNLP
MLBr_02359|M.leprae_Br4923          VSCPIYTYIGDKDWIATQEDMKPWRERTTGAFAIRVFPGD-HFYLNGNLS
MMAR_1778|M.marinum_M               LSCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGD-HFYLNKNLP
MUL_2025|M.ulcerans_Agy99           LSCPIYTFIGSKDWIATREDMEPWRERTTGDFSLREFPGD-HFYLNKNLP
Mflv_3397|M.gilvum_PYR-GCK          LSCPIHAYYGDDDEIATADKVMPWAGRTSAGFTARDFKGH-HFYLNDHLD
Mvan_3130|M.vanbaalenii_PYR-1       LSCPIHAFYGDDDEIATADKVKPWAERTTADFTAREFSGH-HFYLNDHLG
                                    : . * .  *  *   .      *  :*   *    : *  ***:     

MSMEG_4514|M.smegmatis_MC2_155      DVAELVNELW-------
TH_4495|M.thermoresistible__bu      DVAALVSGR--------
MAV_2010|M.avium_104                TVAAQVNAG--------
MAB_2033|M.abscessus_ATCC_1997      EVSACLIQVCNVSPII-
Mb2953|M.bovis_AF2122/97            ELVSDIEDKTLQWHDRA
Rv2928|M.tuberculosis_H37Rv         ELVSDIEDKTLQWHDRA
MLBr_02359|M.leprae_Br4923          ELVCDIEDKTLEWCDRA
MMAR_1778|M.marinum_M               ELVSDIEIGTLQQFDQI
MUL_2025|M.ulcerans_Agy99           ELVSDIEIGTLQQFDQI
Mflv_3397|M.gilvum_PYR-GCK          DVVPDIEQKVWSSLRE-
Mvan_3130|M.vanbaalenii_PYR-1       ELVPDLEQKLWSRLRE-
                                     :   :