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M. smegmatis MC2 155 MSMEG_4514 (-)

annotation: thioesterase domain-containing protein
coordinates: 4599486 - 4600232
length: 248

TGTEVSLESWIKRYPAENTASGPTLVFPHAGGAALAYRPFALALAEAGSDAYVMQYPRRGDRLSHPAPAT
VGDLARDLFEAGDWTRLGPLCLFGHCMGAVVAFEFARVAERNGVAVEALWVSASEAPSAVAASPALPMGE
SEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEAFNRYSCDQGVTIAADIHALGGEQDHRISEDMLR
GWQIHTEGAFTLSMFDGGHFYINDYTDDVAELVNELW*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4514--100% (248)thioesterase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2404cmbtB8e-8058.58% (239) phenyloxazoline synthase MBTB (phenyloxazoline synthetase)
M. gilvum PYR-GCKMflv_2693-7e-9066.11% (239) thioesterase
M. tuberculosis H37RvRv2383cmbtB8e-8058.58% (239) phenyloxazoline synthase MBTB (phenyloxazoline synthetase)
M. leprae Br4923MLBr_02359-9e-2529.61% (233) thioesterase
M. abscessus ATCC 19977MAB_2121c-1e-4741.18% (238) putative phenyloxazoline synthase MbtB/ thioesterase
M. marinum MMMAR_3693-4e-4842.44% (238) thioesterase
M. avium 104MAV_2010-2e-6857.53% (219) phenyloxazoline synthase mbtb
M. thermoresistible (build 8)TH_4495-3e-8060.17% (236) PUTATIVE Thioesterase
M. ulcerans Agy99MUL_3636-3e-4842.44% (238) thioesterase
M. vanbaalenii PYR-1Mvan_3848-1e-8660.17% (241) thioesterase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWR
Rv2383c|M.tuberculosis_H37Rv        MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWR
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           RKGIAVDFATLAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPF
Rv2383c|M.tuberculosis_H37Rv        RKGIAVDFATLAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPF
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           PLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALR
Rv2383c|M.tuberculosis_H37Rv        PLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALR
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           HPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDA
Rv2383c|M.tuberculosis_H37Rv        HPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDA
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           KSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALY
Rv2383c|M.tuberculosis_H37Rv        KSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALY
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           DGREPPALGYTYQEYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL
Rv2383c|M.tuberculosis_H37Rv        DGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANV
Rv2383c|M.tuberculosis_H37Rv        PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANV
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           LARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAA
Rv2383c|M.tuberculosis_H37Rv        LARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAA
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           ARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGD
Rv2383c|M.tuberculosis_H37Rv        ARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGD
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           LFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPG
Rv2383c|M.tuberculosis_H37Rv        LFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPG
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           VIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPS
Rv2383c|M.tuberculosis_H37Rv        VIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPS
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           TEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR
Rv2383c|M.tuberculosis_H37Rv        TEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSV
Rv2383c|M.tuberculosis_H37Rv        VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSV
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           NLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSG
Rv2383c|M.tuberculosis_H37Rv        NLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSG
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           STGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIF
Rv2383c|M.tuberculosis_H37Rv        STGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIF
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           AALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGG
Rv2383c|M.tuberculosis_H37Rv        AALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGG
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           GRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFE
Rv2383c|M.tuberculosis_H37Rv        GRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFE
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           VQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI
Rv2383c|M.tuberculosis_H37Rv        VQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKI
Rv2383c|M.tuberculosis_H37Rv        ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKI
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           SGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAES
Rv2383c|M.tuberculosis_H37Rv        SGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAES
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           IRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGD
Rv2383c|M.tuberculosis_H37Rv        IRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGD
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           RSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQV
Rv2383c|M.tuberculosis_H37Rv        RSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQV
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2693|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3848|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2404c|M.bovis_AF2122/97           VAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLE
Rv2383c|M.tuberculosis_H37Rv        VAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLE
TH_4495|M.thermoresistible__bu      --------------------------------------------------
MAV_2010|M.avium_104                --------------------------------------------------
MMAR_3693|M.marinum_M               --------------------------------------------------
MUL_3636|M.ulcerans_Agy99           --------------------------------------------------
MAB_2121c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02359|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4514|M.smegmatis_MC2_155      --------------MTG--TEVSLESWIKRYPAENTASG-PTLVFPHAGG
Mflv_2693|M.gilvum_PYR-GCK          ---------------------MGFKPWIKRFPAASPGSG-GILVFPHAGG
Mvan_3848|M.vanbaalenii_PYR-1       --------------MIGGHDQLELAPWIKRFPGEQGTS---TIVFPHAGG
Mb2404c|M.bovis_AF2122/97           IANMTSADVMAALDPIEQPAQPAFKPWVKRF-TGTDKPG-AVLVFPHAGG
Rv2383c|M.tuberculosis_H37Rv        IANMTSADVMAALDPIEQPAQPAFKPWVKRF-TGTDKPG-AVLVFPHAGG
TH_4495|M.thermoresistible__bu      ---------MTVLR-------QDFAPWIKRFPAGGERTGRAAVLFPHAGG
MAV_2010|M.avium_104                -------------------------------------------MFPHAGA
MMAR_3693|M.marinum_M               --------------------MARKLGWVRQFHEPDAPESLPLLVFPHAGA
MUL_3636|M.ulcerans_Agy99           --------------------MARKLGWVRQFHEPDAPESLPLLVFPHAGA
MAB_2121c|M.abscessus_ATCC_199      --------------------MDRKLGWIRQFHKPESPDAPLLLIFPHAGA
MLBr_02359|M.leprae_Br4923          -----------MLHVLRPGYAGAVNGHSNNGNDDETSTTPTLYIFPHAGG
                                                                               :*****.

MSMEG_4514|M.smegmatis_MC2_155      AALAYRPFALALAEAGSDAYVMQYPRRGDRLSHPAPATVGDLAR---DLF
Mflv_2693|M.gilvum_PYR-GCK          AAAAYRGLATAFAARGTDAYVMQYPRRAERLSHPAATTVEELAQ---DLF
Mvan_3848|M.vanbaalenii_PYR-1       AAAAYRSFASALSDRGVDTFVVQYPQRGERLAHPAAETVADLAA---DML
Mb2404c|M.bovis_AF2122/97           AAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALAL---ELF
Rv2383c|M.tuberculosis_H37Rv        AAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALAL---ELF
TH_4495|M.thermoresistible__bu      AAAAYRTLAKALSDNGTDTYIVQYPQRAERLRHPAADSISDLAA---QLF
MAV_2010|M.avium_104                AAASYRVLAAALAA-GADTYVVQYPQRAERLGDPAHESVHDLAV---GLF
MMAR_3693|M.marinum_M               GASAYREFSKVLSE-TFNVIVFQYPGRQDRAAEPSCAAISEIAAGAFSEF
MUL_3636|M.ulcerans_Agy99           GASAYREFSKVLSE-TFNVIVFQYPGRQDRAAEPSCAAISEIAAGAFSEF
MAB_2121c|M.abscessus_ATCC_199      GASAYRTLSKASSA-NFNVLVFQYPGRQDRAGEPALPTLSDIAAGAFAEF
MLBr_02359|M.leprae_Br4923          DATYYVPFSREFSA-DIKRIAVHYPGQRDGYGLPALTSIPALADEIFAIM
                                     *  *  ::        .   .:** : :    *:  ::  :*      :

MSMEG_4514|M.smegmatis_MC2_155      EAGDWTRLGPLCLFGHCMGAVVAFEFARVAERNGVAVEALWVSASEAPSA
Mflv_2693|M.gilvum_PYR-GCK          DAGDWSGIAPLQLFGHCLGAVVAFEFARIAEGHGVDVQRLWVSASEAPSA
Mvan_3848|M.vanbaalenii_PYR-1       GALDWAQLGPLRLFGHCMGALVGFEFTRLAAQRGVTVRELWASASQAPST
Mb2404c|M.bovis_AF2122/97           EAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPST
Rv2383c|M.tuberculosis_H37Rv        EAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPST
TH_4495|M.thermoresistible__bu      EAGPWGSVGPLDLFGHCMGAVVAFEFARVAERHAVPVGTLWASAGQAPST
MAV_2010|M.avium_104                RAAPWPGVAPLTLFGHSMGGVVAFEFARVAEANGTPVRKLWVSAGPPPCV
MMAR_3693|M.marinum_M               AASEHNRGLPIITFGHSMGALVAFEFVRLAEANGIDVRHLNVSAAVAPCN
MUL_3636|M.ulcerans_Agy99           AASEHNRGLPIITFGHSMGALVAFEFVRLAEANGIDVRHLNVSAAVAPCN
MAB_2121c|M.abscessus_ATCC_199      QSSEHNRRVPIHTFGHSMGAVVSFEFARLAEAAGLDVHQLTVSSAVAPCN
MLBr_02359|M.leprae_Br4923          KPS-APPEGAVAFFGHSMGGMLAFEVALRFQSAGYRLIALFVSACSAPGY
                                     .       .:  ***.:*.::.**..      .  :  * .*:  .*  

MSMEG_4514|M.smegmatis_MC2_155      VAASPALPMGESEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEAFN
Mflv_2693|M.gilvum_PYR-GCK          VAASPRLPTTDREVLAHMVDLGGTDARLLADEDFVELLLMAVSADYQAFN
Mvan_3848|M.vanbaalenii_PYR-1       VEGSRPVPTSDRELLADIVDLGGTDARLLEDEDFLELLLPAVRADYQAFN
Mb2404c|M.bovis_AF2122/97           VAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALS
Rv2383c|M.tuberculosis_H37Rv        VAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALS
TH_4495|M.thermoresistible__bu      VGEGPPLPTTDADVLADMVDLGGTDPRLLDDEDFVELLVMAVRADYRALS
MAV_2010|M.avium_104                VGDMPELPTTHDGLLADIADLGGTDPELLADEEFSELLTTAVRADYQAFN
MMAR_3693|M.marinum_M               AAAKPAHPSDDEEILNHLGALEGTDTDVFSNRELMRLALPVIKADYHAFD
MUL_3636|M.ulcerans_Agy99           AAAKPAHPSDDEEILNHLGALEGTDTDVFSNRELMRLALRVIKADYHAFD
MAB_2121c|M.abscessus_ATCC_199      IADKPALPTDDDAVLAHMGALEGTNSTVMGNLDVMRMALPVMKGDYQAFN
MLBr_02359|M.leprae_Br4923          IRYKQIKDFSDNDMLDLVVRMTGMNPDFFEDEEFRVGVLPTLRAAR-IIA
                                              .  ::  :  : * :. .: : :.      .: .    : 

MSMEG_4514|M.smegmatis_MC2_155      RYSCDQGVTIAADIHALGGEQDHRISEDMLRGWQIHTEGAFTLSMFDGGH
Mflv_2693|M.gilvum_PYR-GCK          RYACPPDVRVHADIRTLGAHGDHRISPDMLTKWQGHTEGRFTRELFEGGH
Mvan_3848|M.vanbaalenii_PYR-1       RYSCGRDIRVDADIHVLGGQADHRVDQDLLRQWEIHTDAAFTFTMFDGGH
Mb2404c|M.bovis_AF2122/97           GYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGH
Rv2383c|M.tuberculosis_H37Rv        GYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGH
TH_4495|M.thermoresistible__bu      GYRCGPDERIRADIHALRGDRDHRISREWSDRWASHTSGRFTLSTFDGGH
MAV_2010|M.avium_104                GYDPSPDVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGGH
MMAR_3693|M.marinum_M               TYSCAEDIKVATPIHAMGGDQDPYITLGDLYGWGKHTD-TAKVTMFDGGH
MUL_3636|M.ulcerans_Agy99           TYSCAEDIKVATPIHAMGGDQDPYITLGDLYGWGKHTD-TAKVTMFDGGH
MAB_2121c|M.abscessus_ATCC_199      AYQCADGAKVAARIHSIGGDQDPMITMRDLYGWAQHTD-ALEVTLFDGGH
MLBr_02359|M.leprae_Br4923          GYNCPPETTVSCPIYTYIGDKDWIATQEDMKPWRERTTGAFAIRVFPGDH
                                     *       :   *    .. *          *  :*        : *.*

MSMEG_4514|M.smegmatis_MC2_155      FYINDYTDDVAELVNELW--------
Mflv_2693|M.gilvum_PYR-GCK          FYITGHAEAVAELIRAG---------
Mvan_3848|M.vanbaalenii_PYR-1       FYLDDHLDEVAELVSCT---------
Mb2404c|M.bovis_AF2122/97           FYLNDHLDAVARMVSADVR-------
Rv2383c|M.tuberculosis_H37Rv        FYLNDHLDAVARMVSADVR-------
TH_4495|M.thermoresistible__bu      FYLNDHLTDVAALVSGR---------
MAV_2010|M.avium_104                FYLYDHVETVAAQVNAG---------
MMAR_3693|M.marinum_M               FYLRSHIDAVAALLASSAQCGQQA--
MUL_3636|M.ulcerans_Agy99           FYLRSHIDAVAALLASSAQCGQQA--
MAB_2121c|M.abscessus_ATCC_199      FFLNSQTEALAELLVANSASASSPQR
MLBr_02359|M.leprae_Br4923          FYLNGNLSELVCDIEDKTLEWCDRA-
                                    *:: .    :.  :