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MTEPTTRDRILDAAAELYRRQGMSATGLKQISAAARAPFGSIYHHFPGGKEAISAEVIRSEGIRYAAFVG AQLADINPANGIEAVFASAAELLESQDYSEACSIETIALEVASTNERLRGEAAEVFETWLHQLAGWFGQL DIGDEQSRRLATVMLTALEGAFVLCRTLRSVEPMLIAGHGVQAAVHAVLASAQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3237 | - | - | 100% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3287 | - | 8e-13 | 28.80% (184) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0944 | - | 8e-07 | 25.73% (171) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 9e-17 | 30.51% (177) | putative transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv0196 | - | 9e-17 | 30.51% (177) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2447c | - | 3e-41 | 50.00% (188) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2960 | - | 3e-21 | 26.42% (193) | transcriptional regulatory protein |
| M. avium 104 | MAV_0149 | - | 2e-31 | 42.16% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6764 | - | 4e-77 | 76.84% (190) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3160 | - | 4e-14 | 33.53% (170) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_2793 | - | 1e-20 | 33.72% (172) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5860 | - | 9e-76 | 74.87% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3160|M.thermoresistible__bu MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRGS
MUL_2793|M.ulcerans_Agy99 ---MTARER---------LIESAIELLRRNGVAGTGLADLLEHSGTARRS
Mb0202|M.bovis_AF2122/97 --MQGPRER---------MVVSAALLIRERGAHATAISDVLQHSGAPRGS
Rv0196|M.tuberculosis_H37Rv --MQGPRER---------MVVSAALLIRERGAHATAISDVLQHSGAPRGS
MMAR_2960|M.marinum_M MAEDSGRQR---------MVAGAAEMISRRGLNATSVRELAKHTQAPLGS
MSMEG_6764|M.smegmatis_MC2_155 MAELGTRER---------ILQATAELYRRQGMSATGLKQISGAAKAPFGS
Mvan_5860|M.vanbaalenii_PYR-1 MADPSTRSR---------ILDATAELYRRQGMPATGLKQISAAAQAPFGS
Mflv_3237|M.gilvum_PYR-GCK MTEPTTRDR---------ILDAAAELYRRQGMSATGLKQISAAARAPFGS
MAB_2447c|M.abscessus_ATCC_199 -MPANTRDR---------IVAATCELFRRQGMTGTGLKQIAQSAGAPFGS
MAV_0149|M.avium_104 -MATATRER---------FLTAATGLFRRQGYSGTGLKQIVAESRAPLGS
* * :: .: : ..* .*.. :: : :. *
TH_3160|M.thermoresistible__bu IYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAAD-LPTALRELVGVW
MUL_2793|M.ulcerans_Agy99 VYVNFPGGKSELMTEATRTAGRLMDSTLASIAAGGG----QPLVAFADSW
Mb0202|M.bovis_AF2122/97 AYHYFPGGRTQLLCEAVDYAGEHVAAMIN--EAEGG---LELLDALIDKY
Rv0196|M.tuberculosis_H37Rv AYHYFPGGRTQLLCEAVDYAGEHVAAMIN--EAEGG---LELLDALIDKY
MMAR_2960|M.marinum_M TYHYFPGGKYDLATEAVRWADDLTVGVLARELAAGP---QAGLSAFLAMW
MSMEG_6764|M.smegmatis_MC2_155 IYHHFPGGKEAISVEVIRSEGIRYGEFVGAQLADTDP--ATGIPQLFESA
Mvan_5860|M.vanbaalenii_PYR-1 IYHHFPGGKEAISVEVIRREGIRYAELVGAQLADTDP--LTGIPQLFEKA
Mflv_3237|M.gilvum_PYR-GCK IYHHFPGGKEAISAEVIRSEGIRYAAFVGAQLADINP--ANGIEAVFASA
MAB_2447c|M.abscessus_ATCC_199 IYHFFPGGKAQLADEAIRAAGAMYRDLVLAVFDQNGPDLAATIRTAFAAA
MAV_0149|M.avium_104 LYHFFPGGKQDLAVQAIAHTAERYRELLDRVFAKSTD-IGQATVTWFNWA
* **.*: : :. :
TH_3160|M.thermoresistible__bu RDGLEAGDYAVGCPIVAAALG-TER-AARDVAG------VAFADLTGLIS
MUL_2793|M.ulcerans_Agy99 KQTLRASDYAAGCPIVAAALGRTESPSAADVAG------EVFGAWQTVLA
Mb0202|M.bovis_AF2122/97 RQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTA
Rv0196|M.tuberculosis_H37Rv RQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTA
MMAR_2960|M.marinum_M RKIVIDSNFHAGCPVLAVSVEDLPEEHHAPRR----AAATAFQRWTSMLA
MSMEG_6764|M.smegmatis_MC2_155 GRLLQSQDYSEACSIETIALEVASTNEVLRQES-----ATVFENWLTGLA
Mvan_5860|M.vanbaalenii_PYR-1 GRDLEAQDYSEACSIETIALEVASTNERLRVEA-----AEVFQSWLTGLA
Mflv_3237|M.gilvum_PYR-GCK AELLESQDYSEACSIETIALEVASTNERLRGEA-----AEVFETWLHQLA
MAB_2447c|M.abscessus_ATCC_199 ADNLIATDYTDACPIATIALEVASTDEDLRHAT-----AEVFTDWIEQGT
MAV_0149|M.avium_104 ARALQETDYADGCPIGTVACEVASSNEALRQAT-----QAVLASWQSRVA
: :: .*.: : : .: :
TH_3160|M.thermoresistible__bu DKLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDELTLL
MUL_2793|M.ulcerans_Agy99 GRFRAQGVGDDTAESLATTVVAAVEGAVILCLAARSTDPLDRTVPMLQQL
Mb0202|M.bovis_AF2122/97 QRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNL
Rv0196|M.tuberculosis_H37Rv QRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNL
MMAR_2960|M.marinum_M DSLRDAGAAEQDAQQVATLIVASVEGTVAMCRAQQSIAPLDLVTAQLGRA
MSMEG_6764|M.smegmatis_MC2_155 RWFGQLDVDEATSRRLAVITLTALEGAFVLCRTLRSVEPIIAAGQGVQAA
Mvan_5860|M.vanbaalenii_PYR-1 AWFGRLALTEPECRRLAMITLTALEGAFVLCRTLRSIDPIIAAGHGVQAA
Mflv_3237|M.gilvum_PYR-GCK GWFGQLDIGDEQSRRLATVMLTALEGAFVLCRTLRSVEPMLIAGHGVQAA
MAB_2447c|M.abscessus_ATCC_199 ERIADTGLPPGTRRRLILGFITGLEGAFVLSRALRDPEPLFAAGETVAAA
MAV_0149|M.avium_104 AELIGAGVPTAQARRLATFAVASLEGAILLARAHRSTRPLRETGRVVADT
: . : : :**:. :. . :. .: . :
TH_3160|M.thermoresistible__bu CSGSAD---------
MUL_2793|M.ulcerans_Agy99 IAQHTSRPSG-----
Mb0202|M.bovis_AF2122/97 LLAELPERSR-----
Rv0196|M.tuberculosis_H37Rv LLAELPERSR-----
MMAR_2960|M.marinum_M IDAVLPGATSPDAHS
MSMEG_6764|M.smegmatis_MC2_155 VTATLAEKR------
Mvan_5860|M.vanbaalenii_PYR-1 VRAAATTRRS-----
Mflv_3237|M.gilvum_PYR-GCK VHAVLASAQ------
MAB_2447c|M.abscessus_ATCC_199 ATSALAALATHAE--
MAV_0149|M.avium_104 LRAATDRG-------