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RTGVVREGDEIRLSAGVFTVVTLSGGSARLVDAVGEQIVVPLSQLMVDPALELVSGSRPPLCSEEMLAGI PEAAVEQARWWERHIVEILSGRPPGTAAGIRPRPEFDTAKRSLRQRELAKLDELRAAGHDVSRNALQRRR FAYERDGLLGVVDGRHNRRRAVFGRVDDRVVAAVRDAIEGETDLSTGTVQRLQRRVAKTLVATYGADDAP AMPSQPTFYRLVKRLAEGRHTFGSARTRRSLSKQPDGPFGSITVVRPGEMVEIDSTLLDVRVVLDDGMVD RVELTAMVDNATRSIPAAVLRPTTKAVDASLLLARALTPEPMRPGWADALRMSRSVLPHHSLTSVDQRLA DAAARPVIAPETIVCDHGKAYLSQTFRQACCTLGINLQPAHPDCPTDKPKIERTLQSVGTLFAQYVAGYV GSSVERRGKNAEDDAVWSMIELQALLDEWIIAVWQNRPHDGLRDPVTPGKALSPNEKYTALVEVAGYVPV PLDADDYIELLPVQWRTINSYGVRINHRTYDAKALNPYRRQHSGVDAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3222 | - | - | 100% (539) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_3183 | - | 0.0 | 77.82% (478) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_0613 | - | 0.0 | 77.82% (478) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2836 | - | 3e-05 | 29.31% (116) | transposase |
| M. tuberculosis H37Rv | Rv2812 | - | 4e-05 | 29.31% (116) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4893c | - | 2e-52 | 31.13% (514) | integrase/transposase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2928 | - | 2e-06 | 28.24% (131) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv ------------------------------------------MAVGDDEE
Mvan_2928|M.vanbaalenii_PYR-1 ---------------------------------------------MSLEE
MAB_4893c|M.abscessus_ATCC_199 MTAGAERFGIGTRFVYEGQIIDVVQLRSTPKGPEVIASNGLEVMHVALKE
Mflv_3222|M.gilvum_PYR-GCK MRTGVVREGDEIRLSAG-----VFTVVTLSGGSARLVDAVGEQIVVPLSQ
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv KVRAERARAIGLFR------------YQLIWEAADAAHSTKQRGKMVREL
Mvan_2928|M.vanbaalenii_PYR-1 HKRRERANAIGLFR------------YQLICPALEDGLSTRQRGRLVREI
MAB_4893c|M.abscessus_ATCC_199 LLQSSRARLIPTEDGPSADDEQETAAMMLAQLSKAELKTVRERAAHVREV
Mflv_3222|M.gilvum_PYR-GCK LMVDPALELVSGSRPP------LCSEEMLAGIPEAAVEQARWWERHIVEI
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv AS---------------REHTDPFG----------------RRVRISRQT
Mvan_2928|M.vanbaalenii_PYR-1 AE---------------RRHIDPFG----------------TQVQIARAT
MAB_4893c|M.abscessus_ATCC_199 LTGFRRGSEHIKEPDEPRPGFDPCGA------LADRYKAKAEQLNTSVRT
Mflv_3222|M.gilvum_PYR-GCK LSGRPPGTAAG---IRPRPEFDTAKRSLRQRELAKLDELRAAGHDVSRNA
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv IDRWIRGWRAGGFDALVPNPRQCT----PRTPAEVLELAVALRRENPQRT
Mvan_2928|M.vanbaalenii_PYR-1 LDRWIRRYRGGGFEALVPEPRRLA----TRTDTQVLELAASLKRENPART
MAB_4893c|M.abscessus_ATCC_199 VQRWVSNYRRFGEAGLVDHRKPRQ----LGVDQRWVDEALAVMVERTNES
Mflv_3222|M.gilvum_PYR-GCK LQRRRFAYERDGLLGVVDGRHNRRRAVFGRVDDRVVAAVRDAIEGETDLS
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv AAAIRRILRTQLG------------WAPDERTLQRNFHRLGLTG------
Mvan_2928|M.vanbaalenii_PYR-1 VAQVARILRTATG------------WAPSESTLLRHFHRCELMG------
MAB_4893c|M.abscessus_ATCC_199 RCTRKLVMWEATKRIEQRYGTGSV-QIPSKTTAYKVLKILETRYPAFRLS
Mflv_3222|M.gilvum_PYR-GCK TGTVQRLQRRVAKTLVATYGADDAPAMPSQPTFYRLVKRLAEGRHTFG-S
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv -----ATTGSAPAVFGRFEAEHPNALWTGD--------------------
Mvan_2928|M.vanbaalenii_PYR-1 -----PAAGQSAEVFGRFEAADPNELWVGD--------------------
MAB_4893c|M.abscessus_ATCC_199 AARNRDIAGRPQEPYGKLKPTRPGEFMLMDTTPLDVFAYDPATSRSIRVE
Mflv_3222|M.gilvum_PYR-GCK ARTRRSLSKQPDGPFGSITVVRPGEMVEIDSTLLDVRVVLDDG-MVDRVE
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv -------------VLHGIRIDLRKTYLFAFLDDHSRLVPG----------
Mvan_2928|M.vanbaalenii_PYR-1 -------------ALHGPRVGDRKTYLFAFLDDHSRLVVG----------
MAB_4893c|M.abscessus_ATCC_199 LTVAMDWYTRCITALRLTPVSTKAVDVAAVLYQLYRPLPAGPNWPDHACW
Mflv_3222|M.gilvum_PYR-GCK LTAMVDNATRSIPAAVLRPT-TKAVDASLLLARALTPEPMRPGWADALR-
Mb2836|M.bovis_AF2122/97 ------------------------MRLAAALRPALASRG---VPNAVYVD
Rv2812|M.tuberculosis_H37Rv ---------------YRWGHAEDTVRLAAALRPALASRG---VPNAVYVD
Mvan_2928|M.vanbaalenii_PYR-1 ---------------HRFGFAEDTVRLAAALKPALAARG---VPAGIYVD
MAB_4893c|M.abscessus_ATCC_199 PEHGVPRSVLIDPDAIDYTGAKYPQKHEQQAGPPTRSGGPAIVPETIVID
Mflv_3222|M.gilvum_PYR-GCK ---------------MSRSVLPHHSLTSVDQRLADAAARPVIAPETIVCD
. : .* : *
Mb2836|M.bovis_AF2122/97 NGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEI
Rv2812|M.tuberculosis_H37Rv NGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEI
Mvan_2928|M.vanbaalenii_PYR-1 NGSAFVDAWLLRACAKLGIRLVHSAPGRPQGRGKIERFFRTVREQFLVEV
MAB_4893c|M.abscessus_ATCC_199 HGKIYVSEHINSVCARMGISIQPVRLGEGRDKGPVERFFRSVRQGVLEFL
Mflv_3222|M.gilvum_PYR-GCK HGKAYLSQTFRQACCTLGINLQPAHPDCPTDKPKIERTLQSVGTLFAQYV
:*. ::. : .*. :*: : . .: :** :::* . :
Mb2836|M.bovis_AF2122/97 TG----EPDVVGRHYVAD----LAELNRLFTAWVETVYHRSVHS------
Rv2812|M.tuberculosis_H37Rv TG----EPDVVGRHYVAD----LAELNRLFTAWVETVYHRSVHS------
Mvan_2928|M.vanbaalenii_PYR-1 TDTTAEDLTAAGVDHTGA----LLELNRLFMAWVETEYHRRTHT------
MAB_4893c|M.abscessus_ATCC_199 PGYAGPDIASRGLDPQAQAELYIDELEELLRQWVAVYYHHRPHSGLVDPH
Mflv_3222|M.gilvum_PYR-GCK AGYVGSSVERRGKNAEDDAVWSMIELQALLDEWIIAVWQNRPHDGLRDPV
.. . * . : **: *: *: . ::. *
Mb2836|M.bovis_AF2122/97 --ETGQTPLARWSAG----GPIP-LPAPETLTEAFLWEEHRRVT------
Rv2812|M.tuberculosis_H37Rv --ETGQTPLARWSAG----GPIP-LPAPETLTEAFLWEEHRRVT------
Mvan_2928|M.vanbaalenii_PYR-1 --ETGQSPLARWETGWDRLGALPALPTAADLTEAFLWSEFRVVT------
MAB_4893c|M.abscessus_ATCC_199 LPSARMSPAQMYEHGLAG-AGFIEIPRDPDLAYEFLRPELRTIQPYGVQV
Mflv_3222|M.gilvum_PYR-GCK TPGKALSPNEKYTALVEV-AGYVPVPLDADDYIELLPVQWRTIN------
:* : . :* :* : * :
Mb2836|M.bovis_AF2122/97 --------KTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGA
Rv2812|M.tuberculosis_H37Rv --------KTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGA
Mvan_2928|M.vanbaalenii_PYR-1 --------KTATVSLHSNIYRVDPALAGRRVELVFSPFDLQAIEVRHQDR
MAB_4893c|M.abscessus_ATCC_199 DNRIYRGLPQDETHILGELANLPSPYGRHRWPVYSDPDDIRYVYVRHPDN
Mflv_3222|M.gilvum_PYR-GCK ------------------------SYGVRINHRTYDAKALNPYRRQHSGV
. : .. : : .
Mb2836|M.bovis_AF2122/97 PMGRAIPYHIGRHSHPKAKPETP-TAPPKPSGIDYAQLIETAHAAELARG
Rv2812|M.tuberculosis_H37Rv PMRRAIPYHIGRHSHPKAKPETP-TAPPKPSGIDYAQLIETAHAAELARG
Mvan_2928|M.vanbaalenii_PYR-1 SYGPAVAHTITRHAHPKARPETRGEAPPAATGIDYLALTAANHHAQLRDD
MAB_4893c|M.abscessus_ATCC_199 RRWHTLTWELADALN-MPMSDERLSYLRRQAAQQHEEFDDRLILDELLSG
Mflv_3222|M.gilvum_PYR-GCK DAR-----------------------------------------------
Mb2836|M.bovis_AF2122/97 --VNYTALTG----------------------------------------
Rv2812|M.tuberculosis_H37Rv --VNYTALTG----------------------------------------
Mvan_2928|M.vanbaalenii_PYR-1 ERIGYHALYGTQAATDDTA-------------------------------
MAB_4893c|M.abscessus_ATCC_199 WNLSMGTSTTEKRIALRMSRPHATLSYQIQQIGPRPSRPETGQLAPDTAP
Mflv_3222|M.gilvum_PYR-GCK --------------------------------------------------
Mb2836|M.bovis_AF2122/97 ------AADQIPGQLDL-------LTGQEAQPK-----------------
Rv2812|M.tuberculosis_H37Rv ------AADQIPGQLDL-------LTGQEAQPK-----------------
Mvan_2928|M.vanbaalenii_PYR-1 ------GDDQVLGQLSITDLEPGGRTGASADHEGEVSA------------
MAB_4893c|M.abscessus_ATCC_199 EPLLAQGTSAIAADIQIEGTAARCRAAAQASDDDDDDELDDFYAGALEEA
Mflv_3222|M.gilvum_PYR-GCK --------------------------------------------------