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LWSVEALEGVPEEVADRARWWEQHIVEVLTGRRPESPPGQPIRPEFDPAVRSLRQRELTKLEELRAAGHD LALITLQRQRSRYEAKGLLGLVDGRYLAKRPVLGRVDERVVAVVRRLIDNETELSTGTVSRLQRKLEKAL LAEYGPDDAPKAPSQATFYRLVKRLEEGKHTFGSARTRRSLAKQPDGPFGTVTAARPGEMVEIDSTPLDV RVVLDDGVVDRVELTAMVDNVTRSIPAAVLRPTTKAVDAALLLAKALTPEPMRPGWSDALRLSRSVLPHR RLTDIDQRLADAAARPVIAPETIVCDHGKAFLSKTFEQACCSLGINLQPAHPDQPTDKPKVERTLQSVGT LFAQYVAGYVGSSVERRGKNADQDAVWSLVELQALLDEWLVAVWQNRPHDGLRDPVTPGKALTPNEKFAA LVEVAGYVPVPLSADAYIELLPATWRTIGSAGIRVNHRTYDARALNPYRRVDSGVRSRNGRWEVHYDPYD VSQIWVRNHHDDGWITATWTHMRTAAVPFGDTVWKQAQAIVAERGADPVTEAEIAAAADALLDRAERGPD TQQDPPAARRAAARARSIPEPSWPHPSVEGTNQNQEPSEVSTDRPANSDDDDLADVIPLPVFDARKEAEQ WHW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3183 | - | - | 100% (634) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_0613 | - | 0.0 | 100.00% (634) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_3222 | - | 0.0 | 77.82% (478) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2836 | - | 2e-06 | 26.03% (219) | transposase |
| M. tuberculosis H37Rv | Rv2812 | - | 2e-06 | 26.03% (219) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4893c | - | 6e-58 | 32.34% (535) | integrase/transposase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2928 | - | 2e-08 | 26.38% (235) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_2928|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3183|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4893c|M.abscessus_ATCC_199 MTAGAERFGIGTRFVYEGQIIDVVQLRSTPKGPEVIASNGLEVMHVALKE
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv -------MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMV
Mvan_2928|M.vanbaalenii_PYR-1 ----------MSLEEHKRRERANAIGLFRYQLICPALEDGLSTRQRGRLV
Mflv_3183|M.gilvum_PYR-GCK -------MLWSVEALEGVPEEVADRARWWEQHIVEVLTGRRPESPPGQPI
MAB_4893c|M.abscessus_ATCC_199 LLQSSRARLIPTEDGPSADDEQETAAMMLAQLSKAELKTVRERAAHVREV
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv R-----------ELASRE-----------HTDPFGRRVRISRQTIDRWIR
Mvan_2928|M.vanbaalenii_PYR-1 R-----------EIAERR-----------HIDPFGTQVQIARATLDRWIR
Mflv_3183|M.gilvum_PYR-GCK RPEFDPAVRSLRQRELTK-----------LEELRAAGHDLALITLQRQRS
MAB_4893c|M.abscessus_ATCC_199 LTGFRRGSEHIKEPDEPRPGFDPCGALADRYKAKAEQLNTSVRTVQRWVS
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv GWRAGGFDALVP----NPRQCTPRTPAEVLELAVALRRENPQRTAAAIRR
Mvan_2928|M.vanbaalenii_PYR-1 RYRGGGFEALVP----EPRRLATRTDTQVLELAASLKRENPARTVAQVAR
Mflv_3183|M.gilvum_PYR-GCK RYEAKGLLGLVDGRYLAKRPVLGRVDERVVAVVRRLIDNETELSTGTVSR
MAB_4893c|M.abscessus_ATCC_199 NYRRFGEAGLVDHRKPRQLGVDQRWVDEALAVMVERTNESRCTRKLVMWE
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv ILR------------TQLGWAPDERTLQRNFHRLGLTGATTG--------
Mvan_2928|M.vanbaalenii_PYR-1 ILR------------TATGWAPSESTLLRHFHRCELMGPAAG--------
Mflv_3183|M.gilvum_PYR-GCK LQRKLEKALLAEYGPDDAPKAPSQATFYRLVKRLEEGKHTFGSARTR-RS
MAB_4893c|M.abscessus_ATCC_199 ATKRIEQRYG-----TGSVQIPSKTTAYKVLKILETRYPAFRLSAARNRD
Mb2836|M.bovis_AF2122/97 --------------------------------------------------
Rv2812|M.tuberculosis_H37Rv ---SAPAVFGRFEAEHPNALWTGDVLHGIR-------IDLRKTYLFAFLD
Mvan_2928|M.vanbaalenii_PYR-1 ---QSAEVFGRFEAADPNELWVGDALHGPR-------VGDRKTYLFAFLD
Mflv_3183|M.gilvum_PYR-GCK LAKQPDGPFGTVTAARPGEMVEIDSTPLDVRVVL-DDGVVDRVELTAMVD
MAB_4893c|M.abscessus_ATCC_199 IAGRPQEPYGKLKPTRPGEFMLMDTTPLDVFAYDPATSRSIRVELTVAMD
Mb2836|M.bovis_AF2122/97 ----------------------MRLAAALRPALASRG-------------
Rv2812|M.tuberculosis_H37Rv DHSRLVPGYRWG-----HAEDTVRLAAALRPALASRG-------------
Mvan_2928|M.vanbaalenii_PYR-1 DHSRLVVGHRFG-----FAEDTVRLAAALKPALAARG-------------
Mflv_3183|M.gilvum_PYR-GCK NVTRSIPAAVLRPT-TKAVDAALLLAKALTPEPMRPGWSDALRLSRSVLP
MAB_4893c|M.abscessus_ATCC_199 WYTRCITALRLTPVSTKAVDVAAVLYQLYRPLPAGPNWPDHACWPEHGVP
* * .
Mb2836|M.bovis_AF2122/97 ------------------------------------VPNAVYVDNGSPYV
Rv2812|M.tuberculosis_H37Rv ------------------------------------VPNAVYVDNGSPYV
Mvan_2928|M.vanbaalenii_PYR-1 ------------------------------------VPAGIYVDNGSAFV
Mflv_3183|M.gilvum_PYR-GCK HRRLTDIDQRLAD----------------AAARPVIAPETIVCDHGKAFL
MAB_4893c|M.abscessus_ATCC_199 RSVLIDPDAIDYTGAKYPQKHEQQAGPPTRSGGPAIVPETIVIDHGKIYV
.* : *:*. ::
Mb2836|M.bovis_AF2122/97 DAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITG----
Rv2812|M.tuberculosis_H37Rv DAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITG----
Mvan_2928|M.vanbaalenii_PYR-1 DAWLLRACAKLGIRLVHSAPGRPQGRGKIERFFRTVREQFLVEVTDTTAE
Mflv_3183|M.gilvum_PYR-GCK SKTFEQACCSLGINLQPAHPDQPTDKPKVERTLQSVGTLFAQYVAGYVGS
MAB_4893c|M.abscessus_ATCC_199 SEHINSVCARMGISIQPVRLGEGRDKGPVERFFRSVRQGVLEFLPGYAGP
. : .*. :*: : .. .: :** :::* . :..
Mb2836|M.bovis_AF2122/97 EPDVVG----RHYVADLAELNRLFTAWVETVYHRSVHS--------ETGQ
Rv2812|M.tuberculosis_H37Rv EPDVVG----RHYVADLAELNRLFTAWVETVYHRSVHS--------ETGQ
Mvan_2928|M.vanbaalenii_PYR-1 DLTAAG----VDHTGALLELNRLFMAWVETEYHRRTHT--------ETGQ
Mflv_3183|M.gilvum_PYR-GCK SVERRGKNADQDAVWSLVELQALLDEWLVAVWQNRPHDGLRDPVTPGKAL
MAB_4893c|M.abscessus_ATCC_199 DIASRGLDPQAQAELYIDELEELLRQWVAVYYHHRPHSGLVDPHLPSARM
. * . : **: *: *: . ::. *
Mb2836|M.bovis_AF2122/97 TPLARWSAG----GPIP-LPAPETLTEAFLWEEHRRVTKTATVSLHGN--
Rv2812|M.tuberculosis_H37Rv TPLARWSAG----GPIP-LPAPETLTEAFLWEEHRRVTKTATVSLHGN--
Mvan_2928|M.vanbaalenii_PYR-1 SPLARWETGWDRLGALPALPTAADLTEAFLWSEFRVVTKTATVSLHSN--
Mflv_3183|M.gilvum_PYR-GCK TPNEKFAALVEVAGYVP-VPLSADAYIELLPATWRTIGSAGIRVNHRTYD
MAB_4893c|M.abscessus_ATCC_199 SPAQMYEHGLAGAGFIE-IPRDPDLAYEFLRPELRTIQPYGVQVDNRIYR
:* : * : :* :* * : . :
Mb2836|M.bovis_AF2122/97 ------RYEIDPALVGR-----------KVELVFDPFDLTRIEVR-----
Rv2812|M.tuberculosis_H37Rv ------RYEIDPALVGR-----------KVELVFDPFDLTRIEVR-----
Mvan_2928|M.vanbaalenii_PYR-1 ------IYRVDPALAGR-----------RVELVFSPFDLQAIEVR-----
Mflv_3183|M.gilvum_PYR-GCK ARALNPYRRVDSGVRSRNG---------RWEVHYDPYDVSQIWVRNHHDD
MAB_4893c|M.abscessus_ATCC_199 G-----LPQDETHILGELANLPSPYGRHRWPVYSDPDDIRYVYVRHPDNR
. :. : .. : : .* *: : **
Mb2836|M.bovis_AF2122/97 ----------------LAGAPMGRAIPYHIGRHSHPKAKPETP-TAPPKP
Rv2812|M.tuberculosis_H37Rv ----------------LAGAPMRRAIPYHIGRHSHPKAKPETP-TAPPKP
Mvan_2928|M.vanbaalenii_PYR-1 ----------------HQDRSYGPAVAHTITRHAHPKARPETRGEAPPAA
Mflv_3183|M.gilvum_PYR-GCK GWITATWTHMRTAAVPFGDTVWKQAQAIVAERGADPVTEAEIAAAADALL
MAB_4893c|M.abscessus_ATCC_199 RWHTLTWELAD----ALNMPMSDERLSYLRRQAAQQHEEFDDRLILDELL
. : :. . :
Mb2836|M.bovis_AF2122/97 S--GIDYAQLIETAHAAELARG--VNYTALTG---------AADQIPGQL
Rv2812|M.tuberculosis_H37Rv S--GIDYAQLIETAHAAELARG--VNYTALTG---------AADQIPGQL
Mvan_2928|M.vanbaalenii_PYR-1 T--GIDYLALTAANHHAQLRDDERIGYHALYGTQAATDDTAGDDQVLGQL
Mflv_3183|M.gilvum_PYR-GCK D--RAERGPDTQQDPPAARRAAARARSIPEPSWPHPSVEGTNQNQEPSEV
MAB_4893c|M.abscessus_ATCC_199 SGWNLSMGTSTTEKRIALRMSRPHATLSYQIQQIGPRPSRPETGQLAPDT
. * .* :
Mb2836|M.bovis_AF2122/97 DL----------------LTGQEAQPK-----------------------
Rv2812|M.tuberculosis_H37Rv DL----------------LTGQEAQPK-----------------------
Mvan_2928|M.vanbaalenii_PYR-1 SITDLEPGG---------RTGASADHEGEVSA------------------
Mflv_3183|M.gilvum_PYR-GCK STDRPANSDDDDLADVIPLPVFDARKEAEQWHW-----------------
MAB_4893c|M.abscessus_ATCC_199 APEPLLAQGTSAIAADIQIEGTAARCRAAAQASDDDDDDELDDFYAGALE
* .
Mb2836|M.bovis_AF2122/97 --
Rv2812|M.tuberculosis_H37Rv --
Mvan_2928|M.vanbaalenii_PYR-1 --
Mflv_3183|M.gilvum_PYR-GCK --
MAB_4893c|M.abscessus_ATCC_199 EA