For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TAGAERFGIGTRFVYEGQIIDVVQLRSTPKGPEVIASNGLEVMHVALKELLQSSRARLIPTEDGPSADDE QETAAMMLAQLSKAELKTVRERAAHVREVLTGFRRGSEHIKEPDEPRPGFDPCGALADRYKAKAEQLNTS VRTVQRWVSNYRRFGEAGLVDHRKPRQLGVDQRWVDEALAVMVERTNESRCTRKLVMWEATKRIEQRYGT GSVQIPSKTTAYKVLKILETRYPAFRLSAARNRDIAGRPQEPYGKLKPTRPGEFMLMDTTPLDVFAYDPA TSRSIRVELTVAMDWYTRCITALRLTPVSTKAVDVAAVLYQLYRPLPAGPNWPDHACWPEHGVPRSVLID PDAIDYTGAKYPQKHEQQAGPPTRSGGPAIVPETIVIDHGKIYVSEHINSVCARMGISIQPVRLGEGRDK GPVERFFRSVRQGVLEFLPGYAGPDIASRGLDPQAQAELYIDELEELLRQWVAVYYHHRPHSGLVDPHLP SARMSPAQMYEHGLAGAGFIEIPRDPDLAYEFLRPELRTIQPYGVQVDNRIYRGLPQDETHILGELANLP SPYGRHRWPVYSDPDDIRYVYVRHPDNRRWHTLTWELADALNMPMSDERLSYLRRQAAQQHEEFDDRLIL DELLSGWNLSMGTSTTEKRIALRMSRPHATLSYQIQQIGPRPSRPETGQLAPDTAPEPLLAQGTSAIAAD IQIEGTAARCRAAAQASDDDDDDELDDFYAGALEEA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4893c | - | - | 100% (737) | integrase/transposase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2836 | - | 3e-09 | 29.33% (150) | transposase |
M. gilvum PYR-GCK | Mflv_3183 | - | 8e-58 | 32.34% (535) | integrase catalytic subunit |
M. tuberculosis H37Rv | Rv2812 | - | 3e-09 | 29.33% (150) | transposase |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | - | - | - | - | - |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | - | - | - | - | - |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_2928 | - | 4e-13 | 26.74% (258) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment Mb2836|M.bovis_AF2122/97 -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv ------------------------------------------MAVGDDEE Mvan_2928|M.vanbaalenii_PYR-1 ---------------------------------------------MSLEE MAB_4893c|M.abscessus_ATCC_199 MTAGAERFGIGTRFVYEGQIIDVVQLRSTPKGPEVIASNGLEVMHVALKE Mflv_3183|M.gilvum_PYR-GCK ----------------------MLWSVEALEGVPEEVADRARWWEQHIVE Mb2836|M.bovis_AF2122/97 -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv KVRAERARAIGLFR------------YQLIWEAADAAHSTKQRGKMVREL Mvan_2928|M.vanbaalenii_PYR-1 HKRRERANAIGLFR------------YQLICPALEDGLSTRQRGRLVREI MAB_4893c|M.abscessus_ATCC_199 LLQSSRARLIPTEDGPSADDEQETAAMMLAQLSKAELKTVRERAAHVREV Mflv_3183|M.gilvum_PYR-GCK VLTGRRPESPPGQP--------------IRPEFDPAVRSLRQRELTKLEE Mb2836|M.bovis_AF2122/97 -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv AS---------------REHTDPFG----------RRVRISRQTIDRWIR Mvan_2928|M.vanbaalenii_PYR-1 AE---------------RRHIDPFG----------TQVQIARATLDRWIR MAB_4893c|M.abscessus_ATCC_199 LTGFRRGSEHIKEPDEPRPGFDPCGALADRYKAKAEQLNTSVRTVQRWVS Mflv_3183|M.gilvum_PYR-GCK LR--------------------------------AAGHDLALITLQRQRS Mb2836|M.bovis_AF2122/97 -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv GWRAGGFDALVP----NPRQCTPRTPAEVLELAVALRRENPQRTAAAIRR Mvan_2928|M.vanbaalenii_PYR-1 RYRGGGFEALVP----EPRRLATRTDTQVLELAASLKRENPARTVAQVAR MAB_4893c|M.abscessus_ATCC_199 NYRRFGEAGLVD----HRKPRQLGVDQRWVDEALAVMVERTNESRCTRKL Mflv_3183|M.gilvum_PYR-GCK RYEAKGLLGLVDGRYLAKRPVLGRVDERVVAVVRRLIDNETELSTGTVSR Mb2836|M.bovis_AF2122/97 -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv ILRTQLG------------WAPDERTLQRNFHRLGLTG-----------A Mvan_2928|M.vanbaalenii_PYR-1 ILRTATG------------WAPSESTLLRHFHRCELMG-----------P MAB_4893c|M.abscessus_ATCC_199 VMWEATKRIEQRYGTG-SVQIPSKTTAYKVLKILETRYPAFRLSAARNRD Mflv_3183|M.gilvum_PYR-GCK LQRKLEKALLAEYGPDDAPKAPSQATFYRLVKRLEEGKHTFG-SARTRRS Mb2836|M.bovis_AF2122/97 -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv TTGSAPAVFGRFEAEHPNALWTGD-------------------------- Mvan_2928|M.vanbaalenii_PYR-1 AAGQSAEVFGRFEAADPNELWVGD-------------------------- MAB_4893c|M.abscessus_ATCC_199 IAGRPQEPYGKLKPTRPGEFMLMDTTPLDVFAYDPATSRSIRVELTVAMD Mflv_3183|M.gilvum_PYR-GCK LAKQPDGPFGTVTAARPGEMVEIDSTPLDVRVVLDDG--VVDRVELTAMV Mb2836|M.bovis_AF2122/97 -------------------------------------------------- Rv2812|M.tuberculosis_H37Rv -------VLHGIRIDLRKTYLFAFLDDHSRLVPG---------------- Mvan_2928|M.vanbaalenii_PYR-1 -------ALHGPRVGDRKTYLFAFLDDHSRLVVG---------------- MAB_4893c|M.abscessus_ATCC_199 WYTRCITALRLTPVSTKAVDVAAVLYQLYRPLPAGPNWPDHACWPEHGVP Mflv_3183|M.gilvum_PYR-GCK DNVTRSIPAAVLRPTTKAVDAALLLAKALTPEPMRPGWS----------- Mb2836|M.bovis_AF2122/97 ------------------MRLAAALRPALASRG-----VPNAVYVDNGSP Rv2812|M.tuberculosis_H37Rv ---------YRWGHAEDTVRLAAALRPALASRG-----VPNAVYVDNGSP Mvan_2928|M.vanbaalenii_PYR-1 ---------HRFGFAEDTVRLAAALKPALAARG-----VPAGIYVDNGSA MAB_4893c|M.abscessus_ATCC_199 RSVLIDPDAIDYTGAKYPQKHEQQAGPPTRSGGP--AIVPETIVIDHGKI Mflv_3183|M.gilvum_PYR-GCK -------DALRLSRSVLPHRRLTDIDQRLADAAARPVIAPETIVCDHGKA : . .* : *:*. Mb2836|M.bovis_AF2122/97 YVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITG-- Rv2812|M.tuberculosis_H37Rv YVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITG-- Mvan_2928|M.vanbaalenii_PYR-1 FVDAWLLRACAKLGIRLVHSAPGRPQGRGKIERFFRTVREQFLVEVTDTT MAB_4893c|M.abscessus_ATCC_199 YVSEHINSVCARMGISIQPVRLGEGRDKGPVERFFRSVRQGVLEFLPGYA Mflv_3183|M.gilvum_PYR-GCK FLSKTFEQACCSLGINLQPAHPDQPTDKPKVERTLQSVGTLFAQYVAGYV ::. : .*. :*: : .. .: :** :::* . :.. Mb2836|M.bovis_AF2122/97 --EPDVVGRHYVAD----LAELNRLFTAWVETVYHRSVHS--------ET Rv2812|M.tuberculosis_H37Rv --EPDVVGRHYVAD----LAELNRLFTAWVETVYHRSVHS--------ET Mvan_2928|M.vanbaalenii_PYR-1 AEDLTAAGVDHTGA----LLELNRLFMAWVETEYHRRTHT--------ET MAB_4893c|M.abscessus_ATCC_199 GPDIASRGLDPQAQAELYIDELEELLRQWVAVYYHHRPHSGLVDPHLPSA Mflv_3183|M.gilvum_PYR-GCK GSSVERRGKNADQDAVWSLVELQALLDEWLVAVWQNRPHDGLRDPVTPGK . * . : **: *: *: . ::. * Mb2836|M.bovis_AF2122/97 GQTPLARWSAG----GPIP-LPAPETLTEAFLWEEHRRVT---------- Rv2812|M.tuberculosis_H37Rv GQTPLARWSAG----GPIP-LPAPETLTEAFLWEEHRRVT---------- Mvan_2928|M.vanbaalenii_PYR-1 GQSPLARWETGWDRLGALPALPTAADLTEAFLWSEFRVVT---------- MAB_4893c|M.abscessus_ATCC_199 RMSPAQMYEHGLAG-AGFIEIPRDPDLAYEFLRPELRTIQPYGVQVDNRI Mflv_3183|M.gilvum_PYR-GCK ALTPNEKFAALVEV-AGYVPVPLSADAYIELLPATWRTIGSAGIRVN--- :* : . :* :* * : Mb2836|M.bovis_AF2122/97 ----KTATVSLHGNRYEIDPALVGR--KVELVFDPFDLTRIEVRLAGAPM Rv2812|M.tuberculosis_H37Rv ----KTATVSLHGNRYEIDPALVGR--KVELVFDPFDLTRIEVRLAGAPM Mvan_2928|M.vanbaalenii_PYR-1 ----KTATVSLHSNIYRVDPALAGR--RVELVFSPFDLQAIEVRHQDRSY MAB_4893c|M.abscessus_ATCC_199 YRGLPQDETHILGELANLPSPYGRH--RWPVYSDPDDIRYVYVRHPDNRR Mflv_3183|M.gilvum_PYR-GCK ---HRTYDARALNPYRRVDSGVRSRNGRWEVHYDPYDVSQIWVRNHHDDG . . .: . : : : .* *: : ** Mb2836|M.bovis_AF2122/97 GRAIPYHIGRHSHP---KAKPETP-TAPPKPSGIDYAQLIETAHAAELAR Rv2812|M.tuberculosis_H37Rv RRAIPYHIGRHSHP---KAKPETP-TAPPKPSGIDYAQLIETAHAAELAR Mvan_2928|M.vanbaalenii_PYR-1 GPAVAHTITRHAHP---KARPETRGEAPPAATGIDYLALTAANHHAQLRD MAB_4893c|M.abscessus_ATCC_199 WHTLTWELADALN----MPMSDERLSYLRRQAAQQHEEFDDRLILDELLS Mflv_3183|M.gilvum_PYR-GCK WITATWTHMRTAAVPFGDTVWKQAQAIVAERGADPVTEAEIAAAADALLD : . . . . * Mb2836|M.bovis_AF2122/97 G--VNYTALTG--------------------------------------- Rv2812|M.tuberculosis_H37Rv G--VNYTALTG--------------------------------------- Mvan_2928|M.vanbaalenii_PYR-1 DERIGYHALYGTQAATDDTA------------------------------ MAB_4893c|M.abscessus_ATCC_199 GWNLSMGTSTTEKRIALRMSRPHATLSYQIQQIGPRPSRPETGQLAPDTA Mflv_3183|M.gilvum_PYR-GCK RAERGPDTQQDPPAARRAAARAR--------------------------- . : Mb2836|M.bovis_AF2122/97 -------AADQIPGQLDL-------LTGQEAQPK---------------- Rv2812|M.tuberculosis_H37Rv -------AADQIPGQLDL-------LTGQEAQPK---------------- Mvan_2928|M.vanbaalenii_PYR-1 -------GDDQVLGQLSITDLEPGGRTGASADHEGEVSA----------- MAB_4893c|M.abscessus_ATCC_199 PEPLLAQGTSAIAADIQIEGTAARCRAAAQASDDDDDDELDDFYAGALEE Mflv_3183|M.gilvum_PYR-GCK SIPEPSWPHPSVEGTNQNQEPSEVSTDRPANSDDDDLADVIPLPVFDARK : . . . . Mb2836|M.bovis_AF2122/97 ------- Rv2812|M.tuberculosis_H37Rv ------- Mvan_2928|M.vanbaalenii_PYR-1 ------- MAB_4893c|M.abscessus_ATCC_199 A------ Mflv_3183|M.gilvum_PYR-GCK EAEQWHW