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VNSLWDYVSTHYQQLAFDSYQHVSAVVQSVLLATVIGVAIGVLTYRNSLAANLATATSSVILTVPSFALL GLLIPLFGLGVIPSVAALVLYSLLPIIRNTIVGLNAVDPALTDAARGIGLSRLQTLGRVELRLVWPAILS AMRLSTQMSMGVLAIAAYVKGPGLGNLIFAGLARVGSPTALPMALSGTLLIVILALLLDAALVLLGRLTT SKGIR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3108 | - | - | 100% (215) | binding-protein-dependent transport systems inner membrane component |
M. gilvum PYR-GCK | Mflv_1209 | - | 1e-21 | 29.95% (207) | binding-protein-dependent transport systems inner membrane |
M. gilvum PYR-GCK | Mflv_3110 | - | 2e-20 | 36.10% (205) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3782c | proZ | 3e-21 | 30.21% (192) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
M. tuberculosis H37Rv | Rv3756c | proZ | 3e-21 | 30.21% (192) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
M. leprae Br4923 | MLBr_02093 | pstA1 | 7e-05 | 26.75% (157) | membrane-bound component of phosphate transport |
M. abscessus ATCC 19977 | MAB_1225 | - | 9e-52 | 46.67% (210) | ABC transporter permease |
M. marinum M | MMAR_0035 | - | 9e-54 | 47.64% (212) | ABC transporter permease |
M. avium 104 | MAV_0319 | - | 2e-20 | 28.50% (207) | ABC transporter, permease protein |
M. smegmatis MC2 155 | MSMEG_2927 | - | 3e-55 | 49.52% (210) | ABC transporter, permease protein OpuCB |
M. thermoresistible (build 8) | TH_0698 | - | 4e-55 | 48.57% (210) | ABC transporter, permease protein OpuCB |
M. ulcerans Agy99 | MUL_0034 | - | 1e-51 | 46.23% (212) | ABC transporter permease |
M. vanbaalenii PYR-1 | Mvan_5599 | - | 2e-21 | 29.47% (207) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment Mb3782c|M.bovis_AF2122/97 ---------------------------------------------MNFLQ Rv3756c|M.tuberculosis_H37Rv ---------------------------------------------MNFLQ MAB_1225|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2927|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0035|M.marinum_M -------------------------------------------MEAATEF MUL_0034|M.ulcerans_Agy99 -------------------------------------------------- TH_0698|M.thermoresistible__bu -------------------------------------------------- Mflv_3108|M.gilvum_PYR-GCK -------------------------------------------------- MAV_0319|M.avium_104 -------------------------------------------------- Mvan_5599|M.vanbaalenii_PYR-1 -------------------------------------------------- MLBr_02093|M.leprae_Br4923 MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLLSV Mb3782c|M.bovis_AF2122/97 QALSYLLTASNWTGP---------VGLAVRTCEHLEYTAVAVAASALIAV Rv3756c|M.tuberculosis_H37Rv QALSYLLTASNWTGP---------VGLAVRTCEHLEYTAVAVAASALIAV MAB_1225|M.abscessus_ATCC_1997 MG-FVEFVKDRWA------------VLSFLAYQHMSLVLQTLVVAAMCAV MSMEG_2927|M.smegmatis_MC2_155 MG-FVEFVQDRWA------------VLSFLAYQHMSFVVQTLLIATAAAL MMAR_0035|M.marinum_M MG-LYDFVVDRWS------------VLWFLAYQHISLVGQTLILATAIAL MUL_0034|M.ulcerans_Agy99 MG-LYDFVVDRWS------------VLWFLAYQHISLVGQALILATAIAL TH_0698|M.thermoresistible__bu MD-FIEFVRERWS------------VLSFLAYQHMSLVVQTLLLSTLLAV Mflv_3108|M.gilvum_PYR-GCK MNSLWDYVSTHYQ------------QLAFDSYQHVSAVVQSVLLATVIGV MAV_0319|M.avium_104 ----MHYLLTHLD------------DAARLTVVHLRLSLVPVLIGLAIAL Mvan_5599|M.vanbaalenii_PYR-1 ----MRYLVTHLD------------ALWTLSLIHLRLSLIPILLGLLIAV MLBr_02093|M.leprae_Br4923 VVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAV . : . .: Mb3782c|M.bovis_AF2122/97 PVG------LLIGHTGRGTLLVVGAVNGLRALP----TLGVLLLGVLLFG Rv3756c|M.tuberculosis_H37Rv PVG------LLIGHTGRGTLLVVGAVNGLRALP----TLGVLLLGVLLFG MAB_1225|M.abscessus_ATCC_1997 FLG------VLIYRSPWGVASGNALAAIGLTIP----SYALLGVLVGVVG MSMEG_2927|M.smegmatis_MC2_155 VVG------VLIYRSPWASAIGNTLTSVGLTIP----SYALLGVLVAFIG MMAR_0035|M.marinum_M ILG------VLIYNSPLGVAAGNAVTAVGLTIP----SYALLGVLVGIVG MUL_0034|M.ulcerans_Agy99 ILG------VLIYNSPLRVAAGNAVTAVGLTIP----SYALLGVLVGIVG TH_0698|M.thermoresistible__bu AVG------VMLYRSTWGRSLGDSVTSLGLTVP----SYALLGVLVGIFG Mflv_3108|M.gilvum_PYR-GCK AIG------VLTYRNSLAANLATATSSVILTVP----SFALLGLLIPLFG MAV_0319|M.avium_104 PLG------MLVQRRRFARRLTTAVASVVFTIP----SLALFVVLPMIIG Mvan_5599|M.vanbaalenii_PYR-1 PLG------ALVQRTTVLRRLTTVTASIVFTIP----SLALFVVLPLIIP MLBr_02093|M.leprae_Br4923 PLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIATLG :* : :* : :: : . Mb3782c|M.bovis_AF2122/97 ---LGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQV Rv3756c|M.tuberculosis_H37Rv ---LGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQV MAB_1225|M.abscessus_ATCC_1997 ---IGVSPSVIMLVFFGSLPILRNVLVGLTGVDQTLVESARGMGMSRLAT MSMEG_2927|M.smegmatis_MC2_155 ---IGVLPSVIMLVFFGFLPILRNVLVGLGGVDRALIESARGMGMSRLST MMAR_0035|M.marinum_M ---LGVLPSVIMLTFFGVFPILRNVVVGLTGVDKGLVESARGMGMSRLTT MUL_0034|M.ulcerans_Agy99 ---LGVLPSVIMPTFFGVFPILRNVVVGLTGVDKGLVESARGMGMSRLTT TH_0698|M.thermoresistible__bu ---VGVLPSVVLLTFFGFLPILRNVLVGLNGVDAGLVESARAMGMSRPAT Mflv_3108|M.gilvum_PYR-GCK ---LGVIPSVAALVLYSLLPIIRNTIVGLNAVDPALTDAARGIGLSRLQT MAV_0319|M.avium_104 TRILDEANVMVALTAYTAALLVRAVLEALDAVPAQISDAATAVGYPRLTR Mvan_5599|M.vanbaalenii_PYR-1 TRILDEANVIVALTLYTVALLVRAVPEALDAVSPAVLDAATAVGYRPLTR MLBr_02093|M.leprae_Br4923 -FQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREACYALGIPKWKT . :: . : * : ::. .:* Mb3782c|M.bovis_AF2122/97 LLRVEVPNALPLMLGGLRSATLQVVATATVAAYAS--LGGLGGYLIDG-- Rv3756c|M.tuberculosis_H37Rv LLRVEVPNALPLMLGGLRSATLQVVATATVAAYAS--LGGLGGYLIDG-- MAB_1225|M.abscessus_ATCC_1997 LVRLELPLAWPVIMTGIRVSAQMLMGTAAIAAFAL--GPGLGGYIFSG-- MSMEG_2927|M.smegmatis_MC2_155 LLRLEIPLAWPVIMTGVRVSAQMLMGVAAIAAYAL--GPGLGGYIFSG-- MMAR_0035|M.marinum_M LVRLELPLAWPVIMTGVRVSAQMLMGIAAIVAFAL--GPGLGGYIFSG-- MUL_0034|M.ulcerans_Agy99 LVRLELPLAWPVIMTGVRVSAQMLMGIAAIVAFAL--GPGLGGYIFSG-- TH_0698|M.thermoresistible__bu LLRLELPLAWPVIMTGVRISAQMLMGIAAIAAFAL--GPGLGGYIFSG-- Mflv_3108|M.gilvum_PYR-GCK LGRVELRLVWPAILSAMRLSTQMSMGVLAIAAYVK--GPGLGNLIFAG-- MAV_0319|M.avium_104 MMKVELPLAVPVLIAGLRVVVVTNIAMVSVGSVIG--IGGLGSWFTQG-- Mvan_5599|M.vanbaalenii_PYR-1 MLKIELPLALPVLIASLRVVAVTNISMVAVGSVIG--IGGLGTWFTEG-- MLBr_02093|M.leprae_Br4923 IVRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRSINFDIFDGNM : :: . . * :: .: :. : .:. : * Mb3782c|M.bovis_AF2122/97 --IKER----RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL Rv3756c|M.tuberculosis_H37Rv --IKER----RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL MAB_1225|M.abscessus_ATCC_1997 --ISRMGGANATNSVIAGTVGILILAVILDSVLNVVTRLTTPRGIRV--- MSMEG_2927|M.smegmatis_MC2_155 --ISRTGGANATNSIVAGTVGILILAVVLDTVLNIITRLTTPRGIRV--- MMAR_0035|M.marinum_M --ISRMGGANATNSIVAATIGILILAVILDTVLNLIARLTTPRGIRA--- MUL_0034|M.ulcerans_Agy99 --ISRMGGANATNSIVAATIGILILAVILDTVLNVIARLTTPREIRA--- TH_0698|M.thermoresistible__bu --ISRMGGANATNSIIVATVGILLLAVILDAVLNLVTRLTTPRGIRV--- Mflv_3108|M.gilvum_PYR-GCK --LARVGSPTALPMALSGTLLIVILALLLDAALVLLGRLTTSKGIR---- MAV_0319|M.avium_104 --YQTG----KSDQILAGIIALFALAVAVDGLIVLGGRLVTPWAHAVRGG Mvan_5599|M.vanbaalenii_PYR-1 --YQAN----KSDQIIAGIVAIFVLAIVIDTLIMLAGKALTPWTRAQPRA MLBr_02093|M.leprae_Br4923 ASLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLFGAAFRFLATRR . : : *: : : .. Mb3782c|M.bovis_AF2122/97 AAVVDKPAAGGGHALR Rv3756c|M.tuberculosis_H37Rv AAVVDKPAAGGGHALR MAB_1225|M.abscessus_ATCC_1997 ---------------- MSMEG_2927|M.smegmatis_MC2_155 ---------------- MMAR_0035|M.marinum_M ---------------- MUL_0034|M.ulcerans_Agy99 ---------------- TH_0698|M.thermoresistible__bu ---------------- Mflv_3108|M.gilvum_PYR-GCK ---------------- MAV_0319|M.avium_104 ARRSVVAPVVGGAR-- Mvan_5599|M.vanbaalenii_PYR-1 TR--APRAEAGAPT-- MLBr_02093|M.leprae_Br4923 CSGCR-----------