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PRAGARPARQWRSRLARAALPLLSVVVFGVVWQLAAASGIWNQTFVPYPATVWNAFVDVSTTHDGVRGYA GYLLWEHLYMTLRRVFAGVLIGVALGVLLGLLMGSVPWLRSVLEPWLTFLRALPPLAYFFLLVIWLGIDE APKITLLALAALPAAAVPTTAAVVAAPVGLTEAARALGASRGQVIRDVVIPSALPETFTGIRLAVGMAYS AVVAAELFNGIPGVGGLVKDASNYNNTPVVLVGIFAIGISGLVIDGLLRAAERRSVPWRGMI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0724 | - | - | 100% (273) | binding-protein-dependent transport systems inner membrane component |
| M. gilvum PYR-GCK | Mflv_3159 | - | 3e-29 | 30.34% (267) | binding-protein-dependent transport systems inner membrane |
| M. gilvum PYR-GCK | Mflv_1210 | - | 2e-15 | 28.77% (219) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 2e-18 | 32.51% (203) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. tuberculosis H37Rv | Rv3756c | proZ | 2e-18 | 32.51% (203) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | MLBr_02093 | pstA1 | 1e-05 | 25.00% (168) | membrane-bound component of phosphate transport |
| M. abscessus ATCC 19977 | MAB_2176 | - | 1e-128 | 85.61% (271) | ABC transporter permease |
| M. marinum M | MMAR_5299 | proZ | 1e-16 | 30.81% (198) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. avium 104 | MAV_2433 | - | 8e-32 | 28.09% (267) | putative aliphatic sulfonates transport permease protein SsuC |
| M. smegmatis MC2 155 | MSMEG_0113 | - | 1e-128 | 85.07% (268) | taurine transport system permease protein TauC |
| M. thermoresistible (build 8) | TH_4654 | - | 5e-30 | 33.46% (254) | PUTATIVE putative binding-protein-dependent transport systems |
| M. ulcerans Agy99 | MUL_4374 | proZ | 5e-17 | 29.44% (197) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. vanbaalenii PYR-1 | Mvan_0121 | - | 1e-137 | 89.67% (271) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5299|M.marinum_M --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0724|M.gilvum_PYR-GCK -----------------MPR-AGARPAR-QWRSR--------LARAALPL
Mvan_0121|M.vanbaalenii_PYR-1 MSVFVDIAADPDLGARHHARGADARPGRSRWRGR--------VTRAALPL
MAB_2176|M.abscessus_ATCC_1997 MSVFVDIVPE-------ESRGTRAVPRPSQWRVR--------LTRAALPL
MSMEG_0113|M.smegmatis_MC2_155 MSVFVDIVPGS------ETDSPRPAAPSNRGRAI--------LTKALLPL
MAV_2433|M.avium_104 --MSIATALDAAPKR--LGGAASGAPGGLWAR----------RKWEVVRL
TH_4654|M.thermoresistible__bu -VTSLQTARPAPRLRSPAQRRADVTDAQLLHRGEHRTRLGPGRAVPAALA
MLBr_02093|M.leprae_Br4923 --MNLDTLDRPVKAVVLRPISVRRRIKNNVAT----------MFFFTSFL
Mb3782c|M.bovis_AF2122/97 --------------------MNFLQQALSYLLTASNWTGPVG--------
Rv3756c|M.tuberculosis_H37Rv --------------------MNFLQQALSYLLTASNWTGPVG--------
MMAR_5299|M.marinum_M --------------------MNFLQQALSYLSTAANWTGSAG--------
MUL_4374|M.ulcerans_Agy99 --------------------MNFLQQALSYLSTAANWTGSAG--------
Mflv_0724|M.gilvum_PYR-GCK LSVVVFGVVWQLAAASGIWNQTFVPYPATVWNAFVDVSTTHDGVRGYAGY
Mvan_0121|M.vanbaalenii_PYR-1 LSLLVFGVVWQFAAASGVWNQTFVPYPATVWGAFVDVSTTHDGVRGYAGY
MAB_2176|M.abscessus_ATCC_1997 LSVVVFIGVWQLAAASGIWNQTFVPYPSSVWHAFVEVSTDHDGVHGYGGY
MSMEG_0113|M.smegmatis_MC2_155 LSVAVFFAVWQAVAVAGIWNQTFVPYPSAVWRAFIDLSTTHDGVRGYAGY
MAV_2433|M.avium_104 VSPLALLALWQLGSAIGVIAQDVLPAPSLILQAGVELTRNGQ--------
TH_4654|M.thermoresistible__bu VGPLLLVALWLITSQLGILDPRTLPHPFDIARTAAELWSDGR--------
MLBr_02093|M.leprae_Br4923 IALVPLVWLLSVVVARGFYAVTRFDWWTHSLRGVMPEEFAGG-----VYH
.
Mb3782c|M.bovis_AF2122/97 -LAVRTCEHLEYTAVAVAASALIAVPVGLLIG--HTGRGTLLVVGAVNGL
Rv3756c|M.tuberculosis_H37Rv -LAVRTCEHLEYTAVAVAASALIAVPVGLLIG--HTGRGTLLVVGAVNGL
MMAR_5299|M.marinum_M -LAHRTAEHLEYTALAVTASALVAIPIGLIIG--HTGRGQLLVVSAVNGL
MUL_4374|M.ulcerans_Agy99 -LAHRTAEHLEYTALAATASALVAIPIGLIIG--HTGRGQLLVVSAVNGL
Mflv_0724|M.gilvum_PYR-GCK LLWEHLYMTLRRVFAGVLIGVALGVLLGLLMG--SVPWLRSVLEPWLTFL
Mvan_0121|M.vanbaalenii_PYR-1 LLWEHLYMTLRRVLAGVAIGVVLGVLLGLVMG--SVSWVRSVLEPWLTFL
MAB_2176|M.abscessus_ATCC_1997 LLIEHLYMTLRRLLFGVLIGITAGVLLGLLMG--SVGWVRSVLEPWLTFL
MSMEG_0113|M.smegmatis_MC2_155 LLVEHLYMTLRRVVAGVVIGVVLGVLLGLLMG--SVGWLRSVLEPWLTFL
MAV_2433|M.avium_104 -LADALHISTVRVIEGLALGGVIGIVAGAAVG--LSRWVEATVDPPLQMI
TH_4654|M.thermoresistible__bu -LPANVAASLKLSLISLAIGVAAGLALALLAG--LSRIGEALVDGPIQIK
MLBr_02093|M.leprae_Br4923 ALYGSLVQAVVAAIMAVPLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVP
* . . .: . :
Mb3782c|M.bovis_AF2122/97 RALPTLGVLLLGVLLFGLGLGPPLV--ALMLLGIPSLLASTYAGIASVDP
Rv3756c|M.tuberculosis_H37Rv RALPTLGVLLLGVLLFGLGLGPPLV--ALMLLGIPSLLASTYAGIASVDP
MMAR_5299|M.marinum_M RALPTLGVLLLGVLLFGLGLGPPIV--ALMLLGMPPLLAGTYAGIASVDP
MUL_4374|M.ulcerans_Agy99 RALPTLGVLLLGVLLFGLGLGPPIV--ALMLLGMPPLLAGTYAGIASVDP
Mflv_0724|M.gilvum_PYR-GCK RALPPLAYFFLLVIWLGIDEAPKIT--LLALAALPAAAVPTTAAVVAAPV
Mvan_0121|M.vanbaalenii_PYR-1 RALPPLAYFFLLVIWLGIDEAPKIT--LLALAALPPAAVATTAAVVAAPV
MAB_2176|M.abscessus_ATCC_1997 RTLPPLAYFFLLVIWLGIDEAPKIT--LLALAALPPAAVATTAAVVAAPV
MSMEG_0113|M.smegmatis_MC2_155 RALPPLAYFFLLVIWLGIDEAPKIT--LLALAALPPAAVATTAAVVAAPV
MAV_2433|M.avium_104 RALPHLGLIPLFILWFGIGELPKVL--LVALGVVFPLYLNTFSAIRQVDP
TH_4654|M.thermoresistible__bu RAVPTLAIIPLAIIWFGIGDTMKIV--IIATSVLIPVYINTTAQLKGVDL
MLBr_02093|M.leprae_Br4923 SIVAALFIFCLWIATLGFQQSAFAVSLALVLLMLPVVVRSTEEILRLVPD
:. * : * : :*: : : * : .
Mb3782c|M.bovis_AF2122/97 LVVDAARAMGMTESQVLLRVEVPNALPLMLGGLRSAT-LQVVATATVAAY
Rv3756c|M.tuberculosis_H37Rv LVVDAARAMGMTESQVLLRVEVPNALPLMLGGLRSAT-LQVVATATVAAY
MMAR_5299|M.marinum_M LVVDAARAMGMTEAQVVLRVEMPNALPLILGGLRSAT-LQVVATATVAAY
MUL_4374|M.ulcerans_Agy99 LVVDAARAMGMTEAQVVLRVEMPNALPLILGGLRSAT-LQVVATVTVAAY
Mflv_0724|M.gilvum_PYR-GCK GLTEAARALGASRGQVIRDVVIPSALPETFTGIRLAVGMAYSAVVAAELF
Mvan_0121|M.vanbaalenii_PYR-1 GLQEAARALGASRRQVIRDVVVPSALPETFTGIRLAVGMAYSSVVAAELF
MAB_2176|M.abscessus_ATCC_1997 GLVEAARALGASRWQVTRDVVIPAALPETFTGVRLAVGMAYSSVVAAELF
MSMEG_0113|M.smegmatis_MC2_155 GLQEAARALGATRAQVIRDVVVPSALPETFTGIRLAVGMAYSSVVAAELF
MAV_2433|M.avium_104 KMLETAQVLGFSFFQRFRRILVPGTAPQVLVGLRQSLAIAWLTLIVAEQI
TH_4654|M.thermoresistible__bu RHVELAQTVGLSRVQFIRKVALPGALPGFFTGLRLAVTISWTALVVVEQV
MLBr_02093|M.leprae_Br4923 ELREACYALGIPKWKTIVRIVFPIATPGIISGVLLSIARVIGETAPVLVL
: . .:* . : : .* : * : *: : .
Mb3782c|M.bovis_AF2122/97 ASLG-GLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVP
Rv3756c|M.tuberculosis_H37Rv ASLG-GLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVP
MMAR_5299|M.marinum_M ASLG-GLGRYLIDGIKERQFHIALVGALMVAALALSLDGLLALAGWASVP
MUL_4374|M.ulcerans_Agy99 ASLG-GLGRYLIDGIKERQSHIALVGALMVAALALSLDGLLALAGWASVP
Mflv_0724|M.gilvum_PYR-GCK NGIP-GVGGLVKDASNYNNTPVVLVGIFAIGISGLVIDGLLRAAERRSVP
Mvan_0121|M.vanbaalenii_PYR-1 NGIP-GVGGLVKDASNYNNTPVVLVGIFAIGFSGLVIDGLLRAAERRAVP
MAB_2176|M.abscessus_ATCC_1997 NGIP-GVGGLVKDASNYNNTPVVLVGIFSIGISGLVIDAALRAVERRAVP
MSMEG_0113|M.smegmatis_MC2_155 NGIP-GVGGLVKDASNYNNTPVVLVGIFAIGFSGLVIDGLLRAVERRAVP
MAV_2433|M.avium_104 NADK-GIGFLINNARDFLRIDIIIFGLTIYALLGIITDAVVRLIERRAVR
TH_4654|M.thermoresistible__bu NATS-GVGFLMTQARLYGQLEVVVVGLVVYAVFGLAGDHLVRTIERRALS
MLBr_02093|M.leprae_Br4923 VGYSRSINFDIFDGNMASLPLLIYTELTNPEYAGFLRVWGAALTLIILVA
. .:. : :. : .: :
Mb3782c|M.bovis_AF2122/97 GTGRMRKL---------AAVVDKPAAGGGHALR
Rv3756c|M.tuberculosis_H37Rv GTGRMRKL---------AAVVDKPAAGGGHALR
MMAR_5299|M.marinum_M GTGRLSRFWHQSDDRIDVAVSPNSAAVGSHVLR
MUL_4374|M.ulcerans_Agy99 GTGRVSRFWHQPDDRIDVAVSANSAAVGSHVLR
Mflv_0724|M.gilvum_PYR-GCK WRGMI----------------------------
Mvan_0121|M.vanbaalenii_PYR-1 WRGKV----------------------------
MAB_2176|M.abscessus_ATCC_1997 WRGKI----------------------------
MSMEG_0113|M.smegmatis_MC2_155 WIGKV----------------------------
MAV_2433|M.avium_104 YRH------------------------------
TH_4654|M.thermoresistible__bu WRRALGG--------------------------
MLBr_02093|M.leprae_Br4923 GINLFGAAFRFLATRRCSGCR------------