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MVNQAMVNQASGVAPARVPSRQPRGARRDPAIKDAVLAATRTLLVTRGYSATSIDLIAATAKVGRPAIYR LWRSKAHLIHEAAFPDPAPASCGDDIVAEVTRMCRGALEMHADPVVREAVPGLLDDLRLQPAMRKLIDER LEAAARRQLAGQLGDAVADGTVRPSVNADTVMDVVAGAAWYAVVVRKVTDLDAAATQLADLVLRGVLAGP RPATS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3153 | - | - | 100% (215) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4384 | - | 3e-25 | 37.43% (187) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4496 | - | 7e-24 | 39.49% (195) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 6e-23 | 36.17% (188) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 6e-23 | 36.17% (188) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0832 | - | 1e-18 | 31.67% (180) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2979 | - | 6e-22 | 32.81% (192) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4057 | - | 5e-26 | 35.38% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2043 | - | 1e-22 | 35.05% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3283 | - | 7e-23 | 34.90% (192) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 9e-21 | 32.98% (191) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1961 | - | 9e-25 | 36.41% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4780|M.ulcerans_Agy99 -------------------MVADFGRPRDPRIDGAVLRATVELLAETGYA
Mvan_1961|M.vanbaalenii_PYR-1 -----------------------MGRPRNRAIDDAVLRATVELISESSYA
MMAR_2979|M.marinum_M -------MESTAWTDQPEPRVRSQGRPRDARIDAAVLRATTELLEEIGYA
Mb3192c|M.bovis_AF2122/97 -------MKADL---PSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYS
Rv3167c|M.tuberculosis_H37Rv -------MKADL---PSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYS
MAV_4057|M.avium_104 -------MKADP---SGLDKAPGAGRPRDPRIDSAILSATAELLVQTGYS
MSMEG_2043|M.smegmatis_MC2_155 -------MKAEA---SPLGKGVGAGRPRDPRIDAAILRATAELLVEIGYA
Mflv_3153|M.gilvum_PYR-GCK MVNQAMVNQASGVAPARVPSRQPRGARRDPAIKDAVLAATRTLLVTRGYS
TH_3283|M.thermoresistible__bu ---------------MPGSGARSPGRPRDPALDDAIRAAARDVVVEHGYD
MAB_0832|M.abscessus_ATCC_1997 ------------------MDKRQGGRPRDPDKDDAVRETVRRMLAADGYQ
* *: . *: :. :: .*
MUL_4780|M.ulcerans_Agy99 GLLVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPIDAATAVPDTGSPVD
Mvan_1961|M.vanbaalenii_PYR-1 ELSLDAIAARAGTSKPAIYRRWRGKAHLVHEAVFPVDATIEIPRTGSLHG
MMAR_2979|M.marinum_M RLTIPLVAARAGATPPAVYRRFPTKIELVYEAVFPNPTSTELPLTDGLES
Mb3192c|M.bovis_AF2122/97 NLSLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAA
Rv3167c|M.tuberculosis_H37Rv NLSLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAA
MAV_4057|M.avium_104 NISLAAVAERAGTTKSALYRRWSSKAELVHEAAFPTAPTALEAPAGDIAA
MSMEG_2043|M.smegmatis_MC2_155 NLTMAAVAERAQTTKTALYRRWSSKAELVHEAVFPAVPTGLVAPAGDIAA
Mflv_3153|M.gilvum_PYR-GCK ATSIDLIAATAKVGRPAIYRLWRSKAHLIHEAAFPDPAPASCG--DDIVA
TH_3283|M.thermoresistible__bu ATTLALIADRAGVSVPTIYRRWQHKHELIEEAVLHLDTFELPEPTGDLEA
MAB_0832|M.abscessus_ATCC_1997 RTTIPAVARAAGIGAPTIYRRWPTQAAMVESAIADRPWPEELAAPSEFRY
: :* * .::** : : :: .* .
MUL_4780|M.ulcerans_Agy99 DLREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFGHG
Mvan_1961|M.vanbaalenii_PYR-1 DVREMLRRTLAVLSTPAARAALPGLVGEMASDPTLHAALLERFADVLVRD
MMAR_2979|M.marinum_M GIRALLRAAIDLFSRPAVHSALSGLMAELPSEPGLSARLLSRLQSSSYGQ
Mb3192c|M.bovis_AF2122/97 DIRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFAD-LFAA
Rv3167c|M.tuberculosis_H37Rv DIRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFAD-LFAA
MAV_4057|M.avium_104 DMRMMIEATRDVFTTPVVRAALPGLVADMTADPALNARVMSRFAD-LFTA
MSMEG_2043|M.smegmatis_MC2_155 DVHAMIAAARDVFTSPVVRAALPGLIADVSADANLNARVMERFTG-VFAA
Mflv_3153|M.gilvum_PYR-GCK EVTRMCRGALEMHADPVVREAVPGLLDDLRLQPAMRKLIDERLEAAARRQ
TH_3283|M.thermoresistible__bu DLGTWVRLFLTVAMEPAARAAVPGLMSAYSRNPDDYRRLMTRGELPVRAA
MAB_0832|M.abscessus_ATCC_1997 YLPVLVRAVVGYFADPATRAAMPGLLVEYYREPSQYVVLAERTEMPLREA
: *..: * .**: :. : *
MUL_4780|M.ulcerans_Agy99 LTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAW
Mvan_1961|M.vanbaalenii_PYR-1 LNNYLDSAVRRGEVRRGVTAVELAEAVTGMTLLALITR-G---ANVDDAW
MMAR_2979|M.marinum_M LQRFLDHAAASGQATPDVDARILLDMIGGTVMMALANE-----RDLDAAW
Mb3192c|M.bovis_AF2122/97 VRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPD---DMLDDAW
Rv3167c|M.tuberculosis_H37Rv VRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPD---DMLDDAW
MAV_4057|M.avium_104 VRVRLGEAVDRGEAHPDVDPDRLIELIGGATMLRMLLRPE---EELDDAW
MSMEG_2043|M.smegmatis_MC2_155 VRERIVDGIARGEVHAAVSPDRLVEIIGGATMLRLLLVSD---ENLDDEW
Mflv_3153|M.gilvum_PYR-GCK LAGQLGDAVADGTVRPSVNADTVMDVVAGAAWYAVVVRKVTDLDAAATQL
TH_3283|M.thermoresistible__bu IAAMLERAKAAGQAAPDCDPDAVFELIRGATFLRALTHSD----EDAEAF
MAB_0832|M.abscessus_ATCC_1997 FRRAHAGAVGSGERADQPGADALFDTIVGMAVYHGVLRGT-----ADDAL
. . * . : : : * .
MUL_4780|M.ulcerans_Agy99 IDRTTTLLLKGIRKGTPQ-------------
Mvan_1961|M.vanbaalenii_PYR-1 IERTAHLITKGISS-----------------
MMAR_2979|M.marinum_M MDHTTTLLLGGLAR-----------------
Mb3192c|M.bovis_AF2122/97 VDQTTAIVVRGVHRAAPGGSVV---------
Rv3167c|M.tuberculosis_H37Rv VDQTTAIVVRGVHRAAPGGSVV---------
MAV_4057|M.avium_104 VEQTTAIVVHGVRR-----------------
MSMEG_2043|M.smegmatis_MC2_155 VHQTAAIVIHGVTVGR---------------
Mflv_3153|M.gilvum_PYR-GCK ADLVLRGVLAGPRPATS--------------
TH_3283|M.thermoresistible__bu CTRITEAVLRAVRS-----------------
MAB_0832|M.abscessus_ATCC_1997 VEQILDVVDAASSVGRGLHLDETNSDKERKR
: .