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M. gilvum PYR-GCK Mflv_0347 (-)

annotation: FAD-binding domain-containing protein
coordinates: 349030 - 350646
length: 538

AEVPPFSLILGFATETGNSAMVAKKFAQAAAAAGIDVEPQYLNDLDLDALRAATHFVVVTATYGDGELPY
DAEVFWEELSADTPGRLGQLSFAVCGLGDSFYPYFNNAGKLVDARLEELGATRIVDRVDCDLEFEEPSEA
WTAEVVARLAELTTTTGRAAVVPADLAPDSAWTRRNPFPARLAANRLLTSPGSDKSVRHYELDVADSGIV
YRAGDSVGVHPVNDPRLVDAVLARLGVDADVVVPEHVHPVGLLLTEHLELRVPSGALQALVAARTSDPQV
RAILEGGDSAALTGWLYGRDVLDLLALADLGADEVIPTLRPLQHRDYSIASSPLVHPDRIHLTVAAIDYR
ARDRAYRGVASGYLAERAEQVRIHLAPNDGFRLPAPDVPIVMVGPGTGIAPFRAFLQERQATAATGGSWL
FYGGRHRADDFLYGDELVGFQKSGTLDRLSCAFSRDRGPQGPKDYVQHHMTAHAGRLYSWLQDGAHFYVC
GDADHMAKDVHRALHEVIRSAGGLSEDDAHIYVNDLITSRRYLRDVY*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0347--100% (538)FAD-binding domain-containing protein
M. gilvum PYR-GCKMflv_3016-3e-9440.15% (538) molybdopterin oxidoreductase
M. gilvum PYR-GCKMflv_1353-8e-0529.21% (178) oxidoreductase FAD-binding subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2492-1e-16154.39% (535) sulfite reductase
M. marinum MMMAR_3639fdhF7e-9839.45% (550) formate dehydrogenase H FdhF
M. avium 104MAV_2075-1e-10440.29% (551) FdhF protein
M. smegmatis MC2 155MSMEG_0295-1e-0531.52% (184) oxidoreductase, FAD-binding
M. thermoresistible (build 8)TH_2828-3e-0532.40% (179) PUTATIVE ferredoxin
M. ulcerans Agy99MUL_1474fdhF5e-9839.60% (553) formate dehydrogenase H FdhF
M. vanbaalenii PYR-1Mvan_3491-3e-9039.29% (537) molybdopterin oxidoreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               MAPNKDAVKTVCAYCGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLG
MUL_1474|M.ulcerans_Agy99           MAPNKDAVKTVCAYCGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLG
MAV_2075|M.avium_104                -------MNTMCAYCGVGCGMVLQITTDPQTGRRHVAKSVGNKEHPANFG
Mvan_3491|M.vanbaalenii_PYR-1       ------MTRTACSYCGVGCGISVETRTDPATGVPVIARVTGDKLHPSNFG
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               RLCTKGTTTADLLAAP-GRMESAHLRAHRAGHLESIPIDDAITQCAMRLR
MUL_1474|M.ulcerans_Agy99           RLCTKGTTTADLLAAP-GRMESAHLRAHRAGHLESIPIDDAITQCAMRLR
MAV_2075|M.avium_104                RLCTKGATTADLLAAP-GRMDSAHARAGRGEPLEPIGTDQAITRCAKQLR
Mvan_3491|M.vanbaalenii_PYR-1       RLCTKGATHAEMMAATDGRLTTALLRPSRDAEPVATDVDDALAEAGARLR
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               AIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTNQIESNSRLCMAG
MUL_1474|M.ulcerans_Agy99           AIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTKQIESNSRLCMAG
MAV_2075|M.avium_104                AIIDEHGPDAFAMYVSGQMSLEAQYLANKLTKGFIGTNQIESNSRLCMAS
Mvan_3491|M.vanbaalenii_PYR-1       AILDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESNSRLCMAS
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               ASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERVK
MUL_1474|M.ulcerans_Agy99           ASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERVK
MAV_2075|M.avium_104                AGSGYKLSLGADGPPGSYQDFEHADVFFVIGANMADCHPILFLRMMDRVK
Mvan_3491|M.vanbaalenii_PYR-1       AGTGFKQSLGADGPPGSYTDFDCTDLFFVIGSNMADCHPILYLRMADRLK
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               SGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDPQ
MUL_1474|M.ulcerans_Agy99           SGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDPQ
MAV_2075|M.avium_104                AGAKLIVVDPRRTATAEKADLFLQIAPGTDLALLNGLLHLIVENGHTDGE
Mvan_3491|M.vanbaalenii_PYR-1       AGAKLIVVDPRRTATADKADLYLPIRPGTDLALLNGILHLLVENGAVDQE
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               FISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMS
MUL_1474|M.ulcerans_Agy99           FISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMS
MAV_2075|M.avium_104                FIAEFTEGWEVMPSFLEQYTPDRVSEITGIPEQDIRAAAQLIGEADNFMS
Mvan_3491|M.vanbaalenii_PYR-1       FIAEHTQGWESMPEFLAGYPPDRVAAITGLSEADIRAAADMIAEAGDWLS
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               CWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGRE
MUL_1474|M.ulcerans_Agy99           CWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGRE
MAV_2075|M.avium_104                CWTMGLNQSTHGTWNTNAICNLHLATGAICKPGSGPFSLTGQPNAMGGRE
Mvan_3491|M.vanbaalenii_PYR-1       CWTMGLNQSTHGTWNTNAICNLHLATGAICRPGSGPMSLTGQPNAMGGRE
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               MGYMGPGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVSGGVIDMFSRMA
MUL_1474|M.ulcerans_Agy99           MGYMGPGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVSGGVIDMFSRMA
MAV_2075|M.avium_104                MGYMGPGLPGQRSVASAADREFVEDVWGVPRGRLRTEVGTGTIDMFSRMA
Mvan_3491|M.vanbaalenii_PYR-1       MGYMGPGLPGQRSVASAADRAFVEEQWDLEPGTIRADIGPGTVEMFRQMG
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               DGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYAN
MUL_1474|M.ulcerans_Agy99           DGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYAN
MAV_2075|M.avium_104                DGQIKACWIICTNPVASVANRKTVLAGLERAELVIAQDAYLGTETSEYAD
Mvan_3491|M.vanbaalenii_PYR-1       SGDIKAAWIICTNPVASVANRDAVVAGLSTAELVITQDVYADTATNRYAD
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               VLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEMG
MUL_1474|M.ulcerans_Agy99           VLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEMG
MAV_2075|M.avium_104                VLLPAALWAETEGVMVNSERNITLSQPAVAAPGGAMPDWQIIARIACEMG
Mvan_3491|M.vanbaalenii_PYR-1       IVLPATLWAETDAVMVNSDRNLTLLQQSVPPVGDARPDWELICGVARHLG
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               FSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPDG
MUL_1474|M.ulcerans_Agy99           FSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPDG
MAV_2075|M.avium_104                FSEAFSYSCAEEVFEEIKRFWNPTTGYDLRGVSYERLRRQPLQWPCPPQS
Mvan_3491|M.vanbaalenii_PYR-1       FGDAFDYKSSEQIFDEIRRFHNPGTGYDLRGITYERLRDTPVQWPCASAE
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               ASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPDE
MUL_1474|M.ulcerans_Agy99           ASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPDE
MAV_2075|M.avium_104                TADRNPIRYLNDGVSQTQLVREDGTVPRLAFPTPSGRAVFFARPHLQPEE
Mvan_3491|M.vanbaalenii_PYR-1       QSDRNPIRYLNDGVSQDQYVGPDGHRPRLAFPTPSRRAVFHPRPHMDAAE
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               MPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAADM
MUL_1474|M.ulcerans_Agy99           MPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAADM
MAV_2075|M.avium_104                MPDDDYPFLLNTGRLPHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDAARL
Mvan_3491|M.vanbaalenii_PYR-1       LPDDDYPLVLNTGRLQHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDAAAL
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               QICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSINA
MUL_1474|M.ulcerans_Agy99           QICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSINA
MAV_2075|M.avium_104                GIGEHDRVEIASRRGRAVLPAVVSDRVRPGNCFAPFHWNDAFGEYLSINA
Mvan_3491|M.vanbaalenii_PYR-1       GISGGHDVELVTRRGRAVLPAVLTDRVQPGNTWVPFHWNDEHGDHLTVNA
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               VTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADTCADATAPKLL
MUL_1474|M.ulcerans_Agy99           VTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADACADATAPKLL
MAV_2075|M.avium_104                VTNDAVDPISNQPEFKACAVTLTKVAVSHPDSAIG-TGPSAGHDTPESAP
Mvan_3491|M.vanbaalenii_PYR-1       LTNDAVDPDSLQPEFKVCAVRLAPVPAAG---------------------
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2492|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_3639|M.marinum_M               ADTAQFSVTQVDALAELLGVANEPTPQFGPFARSYLAGLIAGLRSETGRR
MUL_1474|M.ulcerans_Agy99           ADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSETGRR
MAV_2075|M.avium_104                TEVREISVSQVDALGELLGVATSFKPEFNELGRSYLAGMLTGLRSDVGRR
Mvan_3491|M.vanbaalenii_PYR-1       ------------------------APEFTETEKLYLAGFFAGIEEG----
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          MAEVPPFS---------------LILG-----------------------
MAB_2492|M.abscessus_ATCC_1997      MTAQPDFS---------------LIVG-----------------------
MMAR_3639|M.marinum_M               MAGVPTLPVSSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQS
MUL_1474|M.ulcerans_Agy99           MAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQS
MAV_2075|M.avium_104                AGGVPTLPPSAPFDSRTRLWVDGLLAGLFSRADASQQAALPEPPQPAAQQ
Mvan_3491|M.vanbaalenii_PYR-1       LPGVPVLPASAPVGPRARLWVDGLLAGRYSRSDTVAETPATEGP------
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          --------------------FATETGNSAMVAKKFAQAAAAA-GIDVEPQ
MAB_2492|M.abscessus_ATCC_1997      --------------------YGTDMGNAEDAAMSFCEALEEATGIKSEAV
MMAR_3639|M.marinum_M               DNAAEA----AVEQPPIVVLWASQTGTAEELAASVA-AQLSAAELPVVLH
MUL_1474|M.ulcerans_Agy99           DNAAEA----AVEQPPIVVLWASQTGTAEELAASVA-AQLSAAELPVVLH
MAV_2075|M.avium_104                PPAAPAGATPAPERAPVVVLWASQTGNAEELAADVA-AQLAAAELPVALH
Mvan_3491|M.vanbaalenii_PYR-1       -----------------LVLWASQTGNAEEFAGRLG-ERLNGAR----LR
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          YLNDLDLDALRAATHFVVVTATYGDGELPYDAEVFWEELSADTPGRLGQL
MAB_2492|M.abscessus_ATCC_1997      ELNQVDIANLQSASHLVVVVSTFGDGEFPDNALLFWEALSAEGAERLAHL
MMAR_3639|M.marinum_M               GMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAATAPSLAGT
MUL_1474|M.ulcerans_Agy99           GMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGT
MAV_2075|M.avium_104                SMDDFPAAELAATRELLLITSTTGDGDAPDNGSGLWRALTGDAAPRLGNT
Mvan_3491|M.vanbaalenii_PYR-1       AMDDVELDDLSEAGEVVIVTSTFGDGGPPDNGAGFWERLESPHAPSLDGV
MSMEG_0295|M.smegmatis_MC2_155      ------------MAAMETSTAPLDEPAGLTDADGFTPLRVKDVIRETTDA
TH_2828|M.thermoresistible__bu      ---------------MSEETV------------GFAPLRIKRVVRETRDA
                                                   .   .              :               

Mflv_0347|M.gilvum_PYR-GCK          SFAVCGLGDSFYPYFNNAGKLVDARLEELGATRIVDRVDCDLEFEEPSEA
MAB_2492|M.abscessus_ATCC_1997      QFAVLALGDSSYEFFCNAGLLLDKRLEELGASRLTERTDVDGPYLQPSKE
MMAR_3639|M.marinum_M               RYSVLALGDSNYADFCGHGRALDHRLAELGASRVTDRVDCEPDYEESAAR
MUL_1474|M.ulcerans_Agy99           RYSVLALGDSNYADFCGHGRALDHRLAELGASRITDRVDCEPDYEESAAR
MAV_2075|M.avium_104                RYAVLALGDSNYDDFCGHGRKLDARLAELGATRIAERVDCEPDYEQAAAK
Mvan_3491|M.vanbaalenii_PYR-1       RYTVLGIGDRSYDNFCGHARSLDARLADLGATRMLDRVECEAYDAQPLAR
MSMEG_0295|M.smegmatis_MC2_155      VSLILDVPELIEDRFRYTAGQFVTVKTTIRGEEHRR--------------
TH_2828|M.thermoresistible__bu      VSLVLDVPPECSDRFRYRAGQFLTLQVEIAGGRHRR--------------
                                       :  :       *   .  .      : . .                 

Mflv_0347|M.gilvum_PYR-GCK          WTAEVVARLAELTTTT----------GRAAVVPADLAPD---SAWTRRNP
MAB_2492|M.abscessus_ATCC_1997      WTTDLVKLLAAGPIGS----------TESAVVTETATP----AKRERHET
MMAR_3639|M.marinum_M               WLQEVLDGLRRTAPPV---------ITAAPVRAASIANR--PQGYTKKRP
MUL_1474|M.ulcerans_Agy99           WLQEVLDGLRRTAPPV---------ITAEPVRAASIASR--PQGYTKKRP
MAV_2075|M.avium_104                WVADVIEALTRTPTAVGGDGGATVSARTSPVAAPSRPNTPAPHTYSKKHP
Mvan_3491|M.vanbaalenii_PYR-1       WADSVVELVAAPGTPP-----------AAPAQEPT--------LFTRAEP
MSMEG_0295|M.smegmatis_MC2_155      --------------------------------------------------
TH_2828|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0347|M.gilvum_PYR-GCK          FPARLAANRLLTSPGSDKSVRHYELDVADSGIVYRAGDSVGVHPVNDPRL
MAB_2492|M.abscessus_ATCC_1997      VEARLVVNRLLTTAESDKEVRHYEVDLAGTGISYEAGDSIAVHAPNDPAL
MMAR_3639|M.marinum_M               LLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQL
MUL_1474|M.ulcerans_Agy99           LLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQL
MAV_2075|M.avium_104                LITDMVRNTTLNGPKSTKDVRHLVFNLPEDAVSYEAGDALGVWPRNSDEL
Mvan_3491|M.vanbaalenii_PYR-1       VAAPLCRNTRLTPQGAAKEVRQIGFDISAHDVTYSVGDSLGVCVVNSDFV
MSMEG_0295|M.smegmatis_MC2_155      ------CYSMSSSPHVGPDLRITVKRDRDGVVSNWINDTAAAGDRLLTAP
TH_2828|M.thermoresistible__bu      ------CYSMSSSPHNGSDLQITVKRDPGGLVSNYLNDTAAAGVEIYASP
                                               .      .::          :    .*: ..        

Mflv_0347|M.gilvum_PYR-GCK          VDAVLARLGVD---ADVVVPEHVHPVGLLLTEHLELRVPSGALQALVAAR
MAB_2492|M.abscessus_ATCC_1997      VEAILAELGVP---AAHRLAGHDLPLGELLSDHLEIRTPSRTLRALVASR
MMAR_3639|M.marinum_M               VDEWLGVTQLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQR
MUL_1474|M.ulcerans_Agy99           VDEWLGVTRLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQR
MAV_2075|M.avium_104                VDEWLAVTGLDGQTPVEVGEHGLMSLRSALTERIEIAHISRDLVRFVQER
Mvan_3491|M.vanbaalenii_PYR-1       VENWLAATDLRGDEAVVVDG-VQQALRDALTAHYDVCKVTSNLVKFVAEH
MSMEG_0295|M.smegmatis_MC2_155      PDGRFVLTTADRDVVTFAGGSGVTPVFSLVNT--TLATTGRRVRMFYANR
TH_2828|M.thermoresistible__bu      PDGRFVLGAADRDVVAFAGGSGITPVYSLIEY--ALATTDRRVKLFYANR
                                     :  :                   .:   :     :      :  :   :

Mflv_0347|M.gilvum_PYR-GCK          TSDP----QVRAILEGGDSAALTGWLYGRDVLDLLALA--DLGADEVIPT
MAB_2492|M.abscessus_ATCC_1997      TDDA----DAVAALSGDGTPVPGSWLYGKDVLDLVRLG--KLAVEELIDN
MMAR_3639|M.marinum_M               TLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSV
MUL_1474|M.ulcerans_Agy99           TLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSV
MAV_2075|M.avium_104                TGDA----KLAELLKPENKRALADWTWGRQSIDLLAQLPVSASAHEWLRV
Mvan_3491|M.vanbaalenii_PYR-1       CRDA----ATAKRLR-NDRGELDRWLVNRNGLDLVREFSVRADPQLWQEV
MSMEG_0295|M.smegmatis_MC2_155      DADS--------VIFRDALTRLTDSHSDRLHVHHHLDTRDGVVSARHITE
TH_2828|M.thermoresistible__bu      SRDS--------VIFGAALEELVAAHPRRLSIVHHFDDESGVVRPAAVEA
                                      *.         :              :  :                  

Mflv_0347|M.gilvum_PYR-GCK          LRPLQHRDYSIASSPLVHPDRIHLTVAAIDYR-ARDRAYRGVASGYLAER
MAB_2492|M.abscessus_ATCC_1997      LRPLQFRDYSIASSPVVYPDTVHLTVATIRYS-NADRTYGGVASTFLADR
MMAR_3639|M.marinum_M               LKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADR
MUL_1474|M.ulcerans_Agy99           LKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADR
MAV_2075|M.avium_104                LKRLQPRLYSISSSPKACPGEVHLTVSPVRYN-FQGVPRRGVCSTYLAAR
Mvan_3491|M.vanbaalenii_PYR-1       LVRLTPRQYSISSSPLVSPNEVQLTVSVVRYRGADGGPRGGVASTYLADL
MSMEG_0295|M.smegmatis_MC2_155      FLGASTVSTAEADFYICGPAPFMDTVERVLLD-------AGVP----AQR
TH_2828|M.thermoresistible__bu      FAEA--VGGDGADFYICGPGPFMDTVEQTLVN-------RGVP----RDR
                                    :          :.     *  .  **              **        

Mflv_0347|M.gilvum_PYR-GCK          --AEQVRIHLAPNDGFRLP-APDVPIVMVGPGTGIAPFRAFLQERQATAA
MAB_2492|M.abscessus_ATCC_1997      --GQAVRVHLRPNHAFRLP-GGHVPIIMIGPGTGIAPFRGFLQERQAAGS
MMAR_3639|M.marinum_M               SPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGH
MUL_1474|M.ulcerans_Agy99           SPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGH
MAV_2075|M.avium_104                SPGDRVAVYLQPSSNFRPPSDPDTPMIMIGPGTGIAPFRGFLQERRALGH
Mvan_3491|M.vanbaalenii_PYR-1       PDGTAVPVFLQRSPHFRPPQDSHTPMIMVGPGTGIAPFRGFLQERRALGH
MSMEG_0295|M.smegmatis_MC2_155      VHLERFTVTPADPAVEAESAATEEVTIVLGRTTVTQPYR-----------
TH_2828|M.thermoresistible__bu      LHLERFELTPASGAAIQAGEQTEEVIIELDRKTTTAPYR-----------
                                         . :                  : :.  *   *:*           

Mflv_0347|M.gilvum_PYR-GCK          TGGSWLFYGGRHRADDFLYGDELVGFQKSGTLDRLSCAFSRDRGPQGPKD
MAB_2492|M.abscessus_ATCC_1997      TGRSWLFFGDRHRAASFLYGEELQGFVASGVLTRLDLAFSRDGANGEPKQ
MMAR_3639|M.marinum_M               TGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRD---QRDKV
MUL_1474|M.ulcerans_Agy99           TGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRD---QRDKV
MAV_2075|M.avium_104                RGPNWLFFGEQHAATDFYYRDELEQMREDGFLTELDLAFSRD---QQHKV
Mvan_3491|M.vanbaalenii_PYR-1       RGPNWLFFGDQHRAQNFYYRDDLQDMVDDGFLNRLDLAFSRD---QARRV
MSMEG_0295|M.smegmatis_MC2_155      ------------AGTTLLQTARLAGLKAP---------------------
TH_2828|M.thermoresistible__bu      ------------SGNTLLQTARIAGLRAP---------------------
                                                 .  :     :  :                        

Mflv_0347|M.gilvum_PYR-GCK          YVQHHMTAHAGRLYSWLQDGAHFYVCGDADHMAKDVHRALHEVIRSAGGL
MAB_2492|M.abscessus_ATCC_1997      YVQHRMSENAAELWAWLQDGAYVYVCGDAEHMAKDVDATLHEIVARCGGM
MMAR_3639|M.marinum_M               YVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGL
MUL_1474|M.ulcerans_Agy99           YVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGL
MAV_2075|M.avium_104                YVQHLMRNRGKQLWSWLQDGAQLYVCGTADPMAKDVDRALCDIAAEFGNL
Mvan_3491|M.vanbaalenii_PYR-1       YVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAGDVDDALTEIIRTHGGM
MSMEG_0295|M.smegmatis_MC2_155      ------------------SSCEVGTCGTCIGQVVEGSARLLNNDALDDDE
TH_2828|M.thermoresistible__bu      ------------------SSCETGSCGTCMARLVAGSARMLNNDALDGDE
                                                      ...    ** .          : :     .. 

Mflv_0347|M.gilvum_PYR-GCK          SEDDAHIYVNDLITSRRYLRDVY
MAB_2492|M.abscessus_ATCC_1997      DAAGAHAYVNELIKNHRYVRDVY
MMAR_3639|M.marinum_M               DPESATAFVHALSADKRYHRDVY
MUL_1474|M.ulcerans_Agy99           DPESATAFVHALSADKRYHRDVY
MAV_2075|M.avium_104                DPDAAKAYVQSLSADKRYHRDVY
Mvan_3491|M.vanbaalenii_PYR-1       SADAARDYKREMVAEKRYVRDVY
MSMEG_0295|M.smegmatis_MC2_155      IAEGWVVTCQALPTSHTVKVVYE
TH_2828|M.thermoresistible__bu      VAEGWVLTCQALPTSRSVHVRYE
                                             . :  .: