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AEVPPFSLILGFATETGNSAMVAKKFAQAAAAAGIDVEPQYLNDLDLDALRAATHFVVVTATYGDGELPY DAEVFWEELSADTPGRLGQLSFAVCGLGDSFYPYFNNAGKLVDARLEELGATRIVDRVDCDLEFEEPSEA WTAEVVARLAELTTTTGRAAVVPADLAPDSAWTRRNPFPARLAANRLLTSPGSDKSVRHYELDVADSGIV YRAGDSVGVHPVNDPRLVDAVLARLGVDADVVVPEHVHPVGLLLTEHLELRVPSGALQALVAARTSDPQV RAILEGGDSAALTGWLYGRDVLDLLALADLGADEVIPTLRPLQHRDYSIASSPLVHPDRIHLTVAAIDYR ARDRAYRGVASGYLAERAEQVRIHLAPNDGFRLPAPDVPIVMVGPGTGIAPFRAFLQERQATAATGGSWL FYGGRHRADDFLYGDELVGFQKSGTLDRLSCAFSRDRGPQGPKDYVQHHMTAHAGRLYSWLQDGAHFYVC GDADHMAKDVHRALHEVIRSAGGLSEDDAHIYVNDLITSRRYLRDVY*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0347 | - | - | 100% (538) | FAD-binding domain-containing protein |
M. gilvum PYR-GCK | Mflv_3016 | - | 3e-94 | 40.15% (538) | molybdopterin oxidoreductase |
M. gilvum PYR-GCK | Mflv_1353 | - | 8e-05 | 29.21% (178) | oxidoreductase FAD-binding subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2492 | - | 1e-161 | 54.39% (535) | sulfite reductase |
M. marinum M | MMAR_3639 | fdhF | 7e-98 | 39.45% (550) | formate dehydrogenase H FdhF |
M. avium 104 | MAV_2075 | - | 1e-104 | 40.29% (551) | FdhF protein |
M. smegmatis MC2 155 | MSMEG_0295 | - | 1e-05 | 31.52% (184) | oxidoreductase, FAD-binding |
M. thermoresistible (build 8) | TH_2828 | - | 3e-05 | 32.40% (179) | PUTATIVE ferredoxin |
M. ulcerans Agy99 | MUL_1474 | fdhF | 5e-98 | 39.60% (553) | formate dehydrogenase H FdhF |
M. vanbaalenii PYR-1 | Mvan_3491 | - | 3e-90 | 39.29% (537) | molybdopterin oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M MAPNKDAVKTVCAYCGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLG MUL_1474|M.ulcerans_Agy99 MAPNKDAVKTVCAYCGVGCGIVLQTTTDPQTGKRRVAKSTGDKSHPANLG MAV_2075|M.avium_104 -------MNTMCAYCGVGCGMVLQITTDPQTGRRHVAKSVGNKEHPANFG Mvan_3491|M.vanbaalenii_PYR-1 ------MTRTACSYCGVGCGISVETRTDPATGVPVIARVTGDKLHPSNFG MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M RLCTKGTTTADLLAAP-GRMESAHLRAHRAGHLESIPIDDAITQCAMRLR MUL_1474|M.ulcerans_Agy99 RLCTKGTTTADLLAAP-GRMESAHLRAHRAGHLESIPIDDAITQCAMRLR MAV_2075|M.avium_104 RLCTKGATTADLLAAP-GRMDSAHARAGRGEPLEPIGTDQAITRCAKQLR Mvan_3491|M.vanbaalenii_PYR-1 RLCTKGATHAEMMAATDGRLTTALLRPSRDAEPVATDVDDALAEAGARLR MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M AIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTNQIESNSRLCMAG MUL_1474|M.ulcerans_Agy99 AIIDEHGPDAVGVYVSGQMSIEAQYLANKLTKGFIGTKQIESNSRLCMAG MAV_2075|M.avium_104 AIIDEHGPDAFAMYVSGQMSLEAQYLANKLTKGFIGTNQIESNSRLCMAS Mvan_3491|M.vanbaalenii_PYR-1 AILDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESNSRLCMAS MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M ASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERVK MUL_1474|M.ulcerans_Agy99 ASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFLRMMERVK MAV_2075|M.avium_104 AGSGYKLSLGADGPPGSYQDFEHADVFFVIGANMADCHPILFLRMMDRVK Mvan_3491|M.vanbaalenii_PYR-1 AGTGFKQSLGADGPPGSYTDFDCTDLFFVIGSNMADCHPILYLRMADRLK MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M SGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDPQ MUL_1474|M.ulcerans_Agy99 SGAKLIVVDPRRTATADKADLFLQIAPGTDLALLNGLLHLIVENEQTDPQ MAV_2075|M.avium_104 AGAKLIVVDPRRTATAEKADLFLQIAPGTDLALLNGLLHLIVENGHTDGE Mvan_3491|M.vanbaalenii_PYR-1 AGAKLIVVDPRRTATADKADLYLPIRPGTDLALLNGILHLLVENGAVDQE MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M FISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMS MUL_1474|M.ulcerans_Agy99 FISEFTEGWEVMPSFLEQFTPDRVSEITGIPSEDIRTAARWIGTAANWMS MAV_2075|M.avium_104 FIAEFTEGWEVMPSFLEQYTPDRVSEITGIPEQDIRAAAQLIGEADNFMS Mvan_3491|M.vanbaalenii_PYR-1 FIAEHTQGWESMPEFLAGYPPDRVAAITGLSEADIRAAADMIAEAGDWLS MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M CWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGRE MUL_1474|M.ulcerans_Agy99 CWTMGLNQSTHGTWNTNALCNLHLATGAICRPGSGPFSLTGQPNAMGGRE MAV_2075|M.avium_104 CWTMGLNQSTHGTWNTNAICNLHLATGAICKPGSGPFSLTGQPNAMGGRE Mvan_3491|M.vanbaalenii_PYR-1 CWTMGLNQSTHGTWNTNAICNLHLATGAICRPGSGPMSLTGQPNAMGGRE MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M MGYMGPGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVSGGVIDMFSRMA MUL_1474|M.ulcerans_Agy99 MGYMGPGLPGQRSVLSAPDREFVEEQWGLPGGALRTDVSGGVIDMFSRMA MAV_2075|M.avium_104 MGYMGPGLPGQRSVASAADREFVEDVWGVPRGRLRTEVGTGTIDMFSRMA Mvan_3491|M.vanbaalenii_PYR-1 MGYMGPGLPGQRSVASAADRAFVEEQWDLEPGTIRADIGPGTVEMFRQMG MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M DGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYAN MUL_1474|M.ulcerans_Agy99 DGEIKACWIICSNPVATVANRKTVLAGLEKAELVISQDAFFETETNEYAN MAV_2075|M.avium_104 DGQIKACWIICTNPVASVANRKTVLAGLERAELVIAQDAYLGTETSEYAD Mvan_3491|M.vanbaalenii_PYR-1 SGDIKAAWIICTNPVASVANRDAVVAGLSTAELVITQDVYADTATNRYAD MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M VLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEMG MUL_1474|M.ulcerans_Agy99 VLLPAALWTESDGVMVNCERNMSLFPKAVDPVGDALPDWQIIARIACEMG MAV_2075|M.avium_104 VLLPAALWAETEGVMVNSERNITLSQPAVAAPGGAMPDWQIIARIACEMG Mvan_3491|M.vanbaalenii_PYR-1 IVLPATLWAETDAVMVNSDRNLTLLQQSVPPVGDARPDWELICGVARHLG MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M FSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPDG MUL_1474|M.ulcerans_Agy99 FSESFSYSSAAEVFEEIKRFSNPATGYDLRGISHDRLRETPLQWPCPPDG MAV_2075|M.avium_104 FSEAFSYSCAEEVFEEIKRFWNPTTGYDLRGVSYERLRRQPLQWPCPPQS Mvan_3491|M.vanbaalenii_PYR-1 FGDAFDYKSSEQIFDEIRRFHNPGTGYDLRGITYERLRDTPVQWPCASAE MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M ASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPDE MUL_1474|M.ulcerans_Agy99 ASNRSPIRYLNDGVSQLQFVRADGTVPRLAFPTATGRAVFFARPHLVPDE MAV_2075|M.avium_104 TADRNPIRYLNDGVSQTQLVREDGTVPRLAFPTPSGRAVFFARPHLQPEE Mvan_3491|M.vanbaalenii_PYR-1 QSDRNPIRYLNDGVSQDQYVGPDGHRPRLAFPTPSRRAVFHPRPHMDAAE MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M MPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAADM MUL_1474|M.ulcerans_Agy99 MPDGDYPFLLNTGRLAHQWHTLTKTGKIAKLNKLNPGPFVEVHPDDAADM MAV_2075|M.avium_104 MPDDDYPFLLNTGRLPHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDAARL Mvan_3491|M.vanbaalenii_PYR-1 LPDDDYPLVLNTGRLQHQWHTMTKTGKVAKLNKLNPGPFVEIHPDDAAAL MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M QICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSINA MUL_1474|M.ulcerans_Agy99 QICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWNDAFGEYLSINA MAV_2075|M.avium_104 GIGEHDRVEIASRRGRAVLPAVVSDRVRPGNCFAPFHWNDAFGEYLSINA Mvan_3491|M.vanbaalenii_PYR-1 GISGGHDVELVTRRGRAVLPAVLTDRVQPGNTWVPFHWNDEHGDHLTVNA MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M VTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADTCADATAPKLL MUL_1474|M.ulcerans_Agy99 VTNDAVDPISRQPEYKACAVTLTKVARPQLQPEPGEPADACADATAPKLL MAV_2075|M.avium_104 VTNDAVDPISNQPEFKACAVTLTKVAVSHPDSAIG-TGPSAGHDTPESAP Mvan_3491|M.vanbaalenii_PYR-1 LTNDAVDPDSLQPEFKVCAVRLAPVPAAG--------------------- MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK -------------------------------------------------- MAB_2492|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3639|M.marinum_M ADTAQFSVTQVDALAELLGVANEPTPQFGPFARSYLAGLIAGLRSETGRR MUL_1474|M.ulcerans_Agy99 ADTAQFSVTQVDALAELLGVGNEPTPQFGPSARSYLAGLIAGLRSETGRR MAV_2075|M.avium_104 TEVREISVSQVDALGELLGVATSFKPEFNELGRSYLAGMLTGLRSDVGRR Mvan_3491|M.vanbaalenii_PYR-1 ------------------------APEFTETEKLYLAGFFAGIEEG---- MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK MAEVPPFS---------------LILG----------------------- MAB_2492|M.abscessus_ATCC_1997 MTAQPDFS---------------LIVG----------------------- MMAR_3639|M.marinum_M MAGVPTLPVSSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQS MUL_1474|M.ulcerans_Agy99 MAGVSTLPISSPFDTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQS MAV_2075|M.avium_104 AGGVPTLPPSAPFDSRTRLWVDGLLAGLFSRADASQQAALPEPPQPAAQQ Mvan_3491|M.vanbaalenii_PYR-1 LPGVPVLPASAPVGPRARLWVDGLLAGRYSRSDTVAETPATEGP------ MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK --------------------FATETGNSAMVAKKFAQAAAAA-GIDVEPQ MAB_2492|M.abscessus_ATCC_1997 --------------------YGTDMGNAEDAAMSFCEALEEATGIKSEAV MMAR_3639|M.marinum_M DNAAEA----AVEQPPIVVLWASQTGTAEELAASVA-AQLSAAELPVVLH MUL_1474|M.ulcerans_Agy99 DNAAEA----AVEQPPIVVLWASQTGTAEELAASVA-AQLSAAELPVVLH MAV_2075|M.avium_104 PPAAPAGATPAPERAPVVVLWASQTGNAEELAADVA-AQLAAAELPVALH Mvan_3491|M.vanbaalenii_PYR-1 -----------------LVLWASQTGNAEEFAGRLG-ERLNGAR----LR MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK YLNDLDLDALRAATHFVVVTATYGDGELPYDAEVFWEELSADTPGRLGQL MAB_2492|M.abscessus_ATCC_1997 ELNQVDIANLQSASHLVVVVSTFGDGEFPDNALLFWEALSAEGAERLAHL MMAR_3639|M.marinum_M GMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAATAPSLAGT MUL_1474|M.ulcerans_Agy99 GMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGT MAV_2075|M.avium_104 SMDDFPAAELAATRELLLITSTTGDGDAPDNGSGLWRALTGDAAPRLGNT Mvan_3491|M.vanbaalenii_PYR-1 AMDDVELDDLSEAGEVVIVTSTFGDGGPPDNGAGFWERLESPHAPSLDGV MSMEG_0295|M.smegmatis_MC2_155 ------------MAAMETSTAPLDEPAGLTDADGFTPLRVKDVIRETTDA TH_2828|M.thermoresistible__bu ---------------MSEETV------------GFAPLRIKRVVRETRDA . . : Mflv_0347|M.gilvum_PYR-GCK SFAVCGLGDSFYPYFNNAGKLVDARLEELGATRIVDRVDCDLEFEEPSEA MAB_2492|M.abscessus_ATCC_1997 QFAVLALGDSSYEFFCNAGLLLDKRLEELGASRLTERTDVDGPYLQPSKE MMAR_3639|M.marinum_M RYSVLALGDSNYADFCGHGRALDHRLAELGASRVTDRVDCEPDYEESAAR MUL_1474|M.ulcerans_Agy99 RYSVLALGDSNYADFCGHGRALDHRLAELGASRITDRVDCEPDYEESAAR MAV_2075|M.avium_104 RYAVLALGDSNYDDFCGHGRKLDARLAELGATRIAERVDCEPDYEQAAAK Mvan_3491|M.vanbaalenii_PYR-1 RYTVLGIGDRSYDNFCGHARSLDARLADLGATRMLDRVECEAYDAQPLAR MSMEG_0295|M.smegmatis_MC2_155 VSLILDVPELIEDRFRYTAGQFVTVKTTIRGEEHRR-------------- TH_2828|M.thermoresistible__bu VSLVLDVPPECSDRFRYRAGQFLTLQVEIAGGRHRR-------------- : : * . . : . . Mflv_0347|M.gilvum_PYR-GCK WTAEVVARLAELTTTT----------GRAAVVPADLAPD---SAWTRRNP MAB_2492|M.abscessus_ATCC_1997 WTTDLVKLLAAGPIGS----------TESAVVTETATP----AKRERHET MMAR_3639|M.marinum_M WLQEVLDGLRRTAPPV---------ITAAPVRAASIANR--PQGYTKKRP MUL_1474|M.ulcerans_Agy99 WLQEVLDGLRRTAPPV---------ITAEPVRAASIASR--PQGYTKKRP MAV_2075|M.avium_104 WVADVIEALTRTPTAVGGDGGATVSARTSPVAAPSRPNTPAPHTYSKKHP Mvan_3491|M.vanbaalenii_PYR-1 WADSVVELVAAPGTPP-----------AAPAQEPT--------LFTRAEP MSMEG_0295|M.smegmatis_MC2_155 -------------------------------------------------- TH_2828|M.thermoresistible__bu -------------------------------------------------- Mflv_0347|M.gilvum_PYR-GCK FPARLAANRLLTSPGSDKSVRHYELDVADSGIVYRAGDSVGVHPVNDPRL MAB_2492|M.abscessus_ATCC_1997 VEARLVVNRLLTTAESDKEVRHYEVDLAGTGISYEAGDSIAVHAPNDPAL MMAR_3639|M.marinum_M LLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQL MUL_1474|M.ulcerans_Agy99 LLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQL MAV_2075|M.avium_104 LITDMVRNTTLNGPKSTKDVRHLVFNLPEDAVSYEAGDALGVWPRNSDEL Mvan_3491|M.vanbaalenii_PYR-1 VAAPLCRNTRLTPQGAAKEVRQIGFDISAHDVTYSVGDSLGVCVVNSDFV MSMEG_0295|M.smegmatis_MC2_155 ------CYSMSSSPHVGPDLRITVKRDRDGVVSNWINDTAAAGDRLLTAP TH_2828|M.thermoresistible__bu ------CYSMSSSPHNGSDLQITVKRDPGGLVSNYLNDTAAAGVEIYASP . .:: : .*: .. Mflv_0347|M.gilvum_PYR-GCK VDAVLARLGVD---ADVVVPEHVHPVGLLLTEHLELRVPSGALQALVAAR MAB_2492|M.abscessus_ATCC_1997 VEAILAELGVP---AAHRLAGHDLPLGELLSDHLEIRTPSRTLRALVASR MMAR_3639|M.marinum_M VDEWLGVTQLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQR MUL_1474|M.ulcerans_Agy99 VDEWLGVTRLDGHTEVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQR MAV_2075|M.avium_104 VDEWLAVTGLDGQTPVEVGEHGLMSLRSALTERIEIAHISRDLVRFVQER Mvan_3491|M.vanbaalenii_PYR-1 VENWLAATDLRGDEAVVVDG-VQQALRDALTAHYDVCKVTSNLVKFVAEH MSMEG_0295|M.smegmatis_MC2_155 PDGRFVLTTADRDVVTFAGGSGVTPVFSLVNT--TLATTGRRVRMFYANR TH_2828|M.thermoresistible__bu PDGRFVLGAADRDVVAFAGGSGITPVYSLIEY--ALATTDRRVKLFYANR : : .: : : : : : Mflv_0347|M.gilvum_PYR-GCK TSDP----QVRAILEGGDSAALTGWLYGRDVLDLLALA--DLGADEVIPT MAB_2492|M.abscessus_ATCC_1997 TDDA----DAVAALSGDGTPVPGSWLYGKDVLDLVRLG--KLAVEELIDN MMAR_3639|M.marinum_M TLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSV MUL_1474|M.ulcerans_Agy99 TLDSNTANQLAELMRPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSV MAV_2075|M.avium_104 TGDA----KLAELLKPENKRALADWTWGRQSIDLLAQLPVSASAHEWLRV Mvan_3491|M.vanbaalenii_PYR-1 CRDA----ATAKRLR-NDRGELDRWLVNRNGLDLVREFSVRADPQLWQEV MSMEG_0295|M.smegmatis_MC2_155 DADS--------VIFRDALTRLTDSHSDRLHVHHHLDTRDGVVSARHITE TH_2828|M.thermoresistible__bu SRDS--------VIFGAALEELVAAHPRRLSIVHHFDDESGVVRPAAVEA *. : : : Mflv_0347|M.gilvum_PYR-GCK LRPLQHRDYSIASSPLVHPDRIHLTVAAIDYR-ARDRAYRGVASGYLAER MAB_2492|M.abscessus_ATCC_1997 LRPLQFRDYSIASSPVVYPDTVHLTVATIRYS-NADRTYGGVASTFLADR MMAR_3639|M.marinum_M LKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADR MUL_1474|M.ulcerans_Agy99 LKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADR MAV_2075|M.avium_104 LKRLQPRLYSISSSPKACPGEVHLTVSPVRYN-FQGVPRRGVCSTYLAAR Mvan_3491|M.vanbaalenii_PYR-1 LVRLTPRQYSISSSPLVSPNEVQLTVSVVRYRGADGGPRGGVASTYLADL MSMEG_0295|M.smegmatis_MC2_155 FLGASTVSTAEADFYICGPAPFMDTVERVLLD-------AGVP----AQR TH_2828|M.thermoresistible__bu FAEA--VGGDGADFYICGPGPFMDTVEQTLVN-------RGVP----RDR : :. * . ** ** Mflv_0347|M.gilvum_PYR-GCK --AEQVRIHLAPNDGFRLP-APDVPIVMVGPGTGIAPFRAFLQERQATAA MAB_2492|M.abscessus_ATCC_1997 --GQAVRVHLRPNHAFRLP-GGHVPIIMIGPGTGIAPFRGFLQERQAAGS MMAR_3639|M.marinum_M SPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGH MUL_1474|M.ulcerans_Agy99 SPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGH MAV_2075|M.avium_104 SPGDRVAVYLQPSSNFRPPSDPDTPMIMIGPGTGIAPFRGFLQERRALGH Mvan_3491|M.vanbaalenii_PYR-1 PDGTAVPVFLQRSPHFRPPQDSHTPMIMVGPGTGIAPFRGFLQERRALGH MSMEG_0295|M.smegmatis_MC2_155 VHLERFTVTPADPAVEAESAATEEVTIVLGRTTVTQPYR----------- TH_2828|M.thermoresistible__bu LHLERFELTPASGAAIQAGEQTEEVIIELDRKTTTAPYR----------- . : : :. * *:* Mflv_0347|M.gilvum_PYR-GCK TGGSWLFYGGRHRADDFLYGDELVGFQKSGTLDRLSCAFSRDRGPQGPKD MAB_2492|M.abscessus_ATCC_1997 TGRSWLFFGDRHRAASFLYGEELQGFVASGVLTRLDLAFSRDGANGEPKQ MMAR_3639|M.marinum_M TGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRD---QRDKV MUL_1474|M.ulcerans_Agy99 TGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNLDLAFSRD---QRDKV MAV_2075|M.avium_104 RGPNWLFFGEQHAATDFYYRDELEQMREDGFLTELDLAFSRD---QQHKV Mvan_3491|M.vanbaalenii_PYR-1 RGPNWLFFGDQHRAQNFYYRDDLQDMVDDGFLNRLDLAFSRD---QARRV MSMEG_0295|M.smegmatis_MC2_155 ------------AGTTLLQTARLAGLKAP--------------------- TH_2828|M.thermoresistible__bu ------------SGNTLLQTARIAGLRAP--------------------- . : : : Mflv_0347|M.gilvum_PYR-GCK YVQHHMTAHAGRLYSWLQDGAHFYVCGDADHMAKDVHRALHEVIRSAGGL MAB_2492|M.abscessus_ATCC_1997 YVQHRMSENAAELWAWLQDGAYVYVCGDAEHMAKDVDATLHEIVARCGGM MMAR_3639|M.marinum_M YVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGL MUL_1474|M.ulcerans_Agy99 YVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGL MAV_2075|M.avium_104 YVQHLMRNRGKQLWSWLQDGAQLYVCGTADPMAKDVDRALCDIAAEFGNL Mvan_3491|M.vanbaalenii_PYR-1 YVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAGDVDDALTEIIRTHGGM MSMEG_0295|M.smegmatis_MC2_155 ------------------SSCEVGTCGTCIGQVVEGSARLLNNDALDDDE TH_2828|M.thermoresistible__bu ------------------SSCETGSCGTCMARLVAGSARMLNNDALDGDE ... ** . : : .. Mflv_0347|M.gilvum_PYR-GCK SEDDAHIYVNDLITSRRYLRDVY MAB_2492|M.abscessus_ATCC_1997 DAAGAHAYVNELIKNHRYVRDVY MMAR_3639|M.marinum_M DPESATAFVHALSADKRYHRDVY MUL_1474|M.ulcerans_Agy99 DPESATAFVHALSADKRYHRDVY MAV_2075|M.avium_104 DPDAAKAYVQSLSADKRYHRDVY Mvan_3491|M.vanbaalenii_PYR-1 SADAARDYKREMVAEKRYVRDVY MSMEG_0295|M.smegmatis_MC2_155 IAEGWVVTCQALPTSHTVKVVYE TH_2828|M.thermoresistible__bu VAEGWVLTCQALPTSRSVHVRYE . : .: