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MPCGHQFGSPQQLTDAGGAVVQEWVISDLRESSVALPGYTARGQVWEASATVRAVTGTVTPIIPNLYTVT AAGQRYPVLWQIASPQGLPATTLGEGQASSGAIYFDAVGPQPMAVVYDNGTPTQLFWCCTGSMMMMPMEK CPMCADMQRACPHRPGGM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2854 | - | - | 100% (158) | hypothetical protein Mflv_2854 |
| M. gilvum PYR-GCK | Mflv_1515 | - | 9e-21 | 41.67% (120) | FHA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1961c | mpt63 | 3e-28 | 44.44% (126) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 KD |
| M. tuberculosis H37Rv | Rv1926c | mpt63 | 3e-28 | 44.44% (126) | immunogenic protein MPT63 (antigen MPT63/MPB63) (16 kDa |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0462c | - | 1e-42 | 51.18% (170) | hypothetical protein MAB_0462c |
| M. marinum M | MMAR_2839 | - | 8e-29 | 45.24% (126) | immunogenic protein Mpt63 |
| M. avium 104 | MAV_3737 | - | 1e-20 | 37.19% (121) | hypothetical protein MAV_3737 |
| M. smegmatis MC2 155 | MSMEG_0828 | - | 2e-25 | 45.83% (120) | immunogenic protein MPT63 |
| M. thermoresistible (build 8) | TH_4151 | - | 3e-19 | 36.36% (121) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_2071 | - | 4e-14 | 34.34% (99) | hypothetical protein MUL_2071 |
| M. vanbaalenii PYR-1 | Mvan_5241 | - | 9e-23 | 42.50% (120) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1961c|M.bovis_AF2122/97 MKLTTMIKTAVAVVAM------AAIATFAAPVALAAYPITGKLGSELTMT
Rv1926c|M.tuberculosis_H37Rv MKLTTMIKTAVAVVAM------AAIATFAAPVALAAYPITGKLGSELTMT
MMAR_2839|M.marinum_M MKLTTMIKTAVAVVAI------ATIATITAPIAFAAYPITGKFGSELKMT
MSMEG_0828|M.smegmatis_MC2_155 MKISQLTIAAAAALAISGAAGTAGMATAFAEAAQAAQVSANPLGSQARLE
TH_4151|M.thermoresistible__bu --MNSKILAAPVVLAT------AAGLALATAAPAPARPGVADFGATQHLH
MAV_3737|M.avium_104 MKVTKNAVLTAAAAGG-----IAAASVFAATPAVAAP-NIQGFGVSEQLV
MUL_2071|M.ulcerans_Agy99 MEFIATTMKTAVGAAA-----IAAASVFGAASASAAPPTIQGFGTSERLV
Mvan_5241|M.vanbaalenii_PYR-1 MKFKP-TVAAIITTAA-----AAAVGVVGAGSASADA-EVQYLGQPGELV
Mflv_2854|M.gilvum_PYR-GCK ----------------------------MP--------CGHQFGSPQQLT
MAB_0462c|M.abscessus_ATCC_199 MGALRPLALALATAGF------FLGGLLAPPLGHAAGSCPHRFGAAQQLA
. :* :
Mb1961c|M.bovis_AF2122/97 DTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVS
Rv1926c|M.tuberculosis_H37Rv DTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVS
MMAR_2839|M.marinum_M DSVGQVVLGWTVSDLKSSSDVIPGYPVAGQVWEATATVNAISGPVTPAIS
MSMEG_0828|M.smegmatis_MC2_155 N--GDVVQAWTISDLKPSSDPIP-YAVQGTLWEATATDEAVSGSVIPIVS
TH_4151|M.thermoresistible__bu D--GGVTIAYTLEELEPSDDVVSNVALQGRLWEVSVTVEAVEGAATPVIP
MAV_3737|M.avium_104 D--GPLVTDYTVSNLQPSNVSIPGYTPKGTLYQADISVRSDGGVVTPMVH
MUL_2071|M.ulcerans_Agy99 D--GPMVTSYTVGNLQLSDVTIAGYLPQGQLYSADVTGRSVTGTITPLVS
Mvan_5241|M.vanbaalenii_PYR-1 N--GSVIQHWTVTGLKPSSDVIP-YRPVGTLWEATATDEAIAGTVTPIVS
Mflv_2854|M.gilvum_PYR-GCK DAGGAVVQEWVISDLRESSVALPGYTARGQVWEASATVRAVTGTVTPIIP
MAB_0462c|M.abscessus_ATCC_199 DAGGS--QEWTVTGLKKSAAVLPGYAPAGQLWEASATVRAERGTITPLIP
: * : : *. * :. * ::.. : .: * * :
Mb1961c|M.bovis_AF2122/97 QFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTI
Rv1926c|M.tuberculosis_H37Rv QFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTI
MMAR_2839|M.marinum_M QFNARTADGVNYRVLWQASGPNTISGATIPQGASSTGKIYFDVTGPAPTI
MSMEG_0828|M.smegmatis_MC2_155 NLNARAANGENYRVLFQVATPQGVNPSTLAPGQKTTGKVYFDVTGEAPTT
TH_4151|M.thermoresistible__bu FFNARSADGQNYRALFTAVGEEALSGATLGQGQETEGNIYFDVTGAPPTE
MAV_3737|M.avium_104 DFIARGPNGQNYRVIDNVAVPNGLSPAPIPQGTESTGTLYFDVTGAPPNG
MUL_2071|M.ulcerans_Agy99 SFSARAANGDTYGVVNEVPAPGGLNPAPILQGNSQSGVLYF---------
Mvan_5241|M.vanbaalenii_PYR-1 NLNARAENGDTYRVLFGVATEQGVNPSTLAQGQKTTGKIYFDVTGQQPDS
Mflv_2854|M.gilvum_PYR-GCK NLYTVTAAGQRYPVLWQIASPQGLPATTLGEGQASSGAIYFDAVGPQPMA
MAB_0462c|M.abscessus_ATCC_199 NL-AAHAMGGHYPVLWQVATDQGLPATTLAEGQSSSGTIYFDVTGPDPVA
: : * * .: : :.: * * :**
Mb1961c|M.bovis_AF2122/97 VAMNNGM-EDLLIWEP----------------------------------
Rv1926c|M.tuberculosis_H37Rv VAMNNGM-EDLLIWEP----------------------------------
MMAR_2839|M.marinum_M VAMNNGM-EDLMIWGP----------------------------------
MSMEG_0828|M.smegmatis_MC2_155 VVYNDGE-RDLLAWSQTAASTTSPRPAATGSGTSASTPARTAPVTTAPAS
TH_4151|M.thermoresistible__bu VVYNDAV-QDRLIWR-----------------------------------
MAV_3737|M.avium_104 VVYNDGM-QDVLMWTSNVPSSAPGAPNSPAPG---------APNSPAPGA
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 VFYSDGG-SEVLLWLEAPPAPATGSAGSGASGYGSEASPSAAADTATPET
Mflv_2854|M.gilvum_PYR-GCK VVYDNGT-PTQLFWCCTGSM-----------MMMPMEK--------CPMC
MAB_0462c|M.abscessus_ATCC_199 VVYTVGAGAPAMMWCCEAAMGTSANTAMDPAMKAKMQANMKAMKADCPCC
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_0828|M.smegmatis_MC2_155 NTPATELVPESPAVAPTGAAPAAAPGAGAAATDIPGSTVPPLAEDAADEA
TH_4151|M.thermoresistible__bu --------------------------------------------------
MAV_3737|M.avium_104 P-PAPAAHT-----------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 PGTTPAAETPTSVVP----TPVAAPAGSSGTPLPEGSSGTPLPEGSSGTP
Mflv_2854|M.gilvum_PYR-GCK ADMQRACP--------HRPGGM----------------------------
MAB_0462c|M.abscessus_ATCC_199 KDLPAAAPGTDCPCCGPTPAGA----------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_0828|M.smegmatis_MC2_155 LAEELTEDLPDELSQDSVTPGESVGTPLPAAVQQAPAAPAPGQPAPAAPG
TH_4151|M.thermoresistible__bu --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 LPAG-------------AAPVEAGPAPVPAGVAPAPHGSSGTPLPAGAPA
Mflv_2854|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0462c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 --------------------------------------------------
Rv1926c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2839|M.marinum_M --------------------------------------------------
MSMEG_0828|M.smegmatis_MC2_155 AQDIPAAPAGEVPAAPVTPAPAAPVDGSTTPTVPAGSDAPLTAGGIPTLV
TH_4151|M.thermoresistible__bu --------------------------------------------------
MAV_3737|M.avium_104 --------------------------------------------------
MUL_2071|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5241|M.vanbaalenii_PYR-1 VEGVQPAPAPGAPTTTVVVPAPPA--------------------------
Mflv_2854|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0462c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1961c|M.bovis_AF2122/97 ----------
Rv1926c|M.tuberculosis_H37Rv ----------
MMAR_2839|M.marinum_M ----------
MSMEG_0828|M.smegmatis_MC2_155 PAANPGAPTP
TH_4151|M.thermoresistible__bu ----------
MAV_3737|M.avium_104 ----------
MUL_2071|M.ulcerans_Agy99 ----------
Mvan_5241|M.vanbaalenii_PYR-1 ----------
Mflv_2854|M.gilvum_PYR-GCK ----------
MAB_0462c|M.abscessus_ATCC_199 ----------