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MVTHQRDSTRTLFGHPIGLTNLFGVELWERFSFYGMLTILGYYLYYSVAEGGLGLPQATATGIVGAYGGL VYLSTVLGGWIADRVLGMERTVFYGGVVVMLGHIALAVLPGLAGVGAGLVLVALGSGALKANASSLLGTL YAKGDPRADGGFTLFYLGINLGAFIGPLITGLLQTRVGFHYGFGAAAIGMALGLLQYVAFRRNLGEHGRE VPNPLPRGAIGKTASVFAVVVLVVAAAVALRLVTLENLSQVTTGVIVIASVAYFVVLFRSPKVTAPERIR VRAFIPLFVANAVFWSLFQQIFTVLAVYSDERMNWSIFGWTAPSNWIGSIEPIWIIALSPLFALMWTRLG KRAPTTPRKFAYGVIGMGVAFLCFVPLAGVSAVPALVVLAILGVFAVSELLLSPIGLSVTTKLAPQAFRA QMMALYFFSVGLGTSMSGVLAGYYDTSREAAYFGVLGAIAVVAGVVVFAISPWISRQMEGVH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2746 | - | - | 100% (482) | amino acid/peptide transporter |
| M. gilvum PYR-GCK | Mflv_1475 | - | 1e-06 | 28.83% (163) | major facilitator transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1660 | - | 5e-05 | 22.83% (403) | drug efflux membrane protein |
| M. tuberculosis H37Rv | Rv1634 | - | 9e-05 | 22.83% (403) | drug efflux membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1338 | - | 4e-07 | 30.26% (152) | putative membrane efflux protein |
| M. marinum M | MMAR_0690 | - | 1e-05 | 29.09% (220) | putative transport protein |
| M. avium 104 | MAV_3702 | - | 1e-07 | 23.87% (243) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_3533 | - | 0.0 | 78.79% (481) | di-/tripeptide transporter |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3792 | - | 0.0 | 86.93% (482) | amino acid/peptide transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1660|M.bovis_AF2122/97 ------------------------------------MTETASETGSWREL
Rv1634|M.tuberculosis_H37Rv ------------------------------------MTETASETGSWREL
Mflv_2746|M.gilvum_PYR-GCK --------------------------------------MVTHQRDSTRTL
Mvan_3792|M.vanbaalenii_PYR-1 --------------------------------------MTIREQGDRRTF
MSMEG_3533|M.smegmatis_MC2_155 -MPQNTLHTAGFPFAHRIAGFSALPADALTERGKVTPMGEAHDTQARRTV
MMAR_0690|M.marinum_M ------------------------------------------MTDSSRRV
MAB_1338|M.abscessus_ATCC_1997 ----------------------------------------MTDLANDEQL
MAV_3702|M.avium_104 MTALNDSERAVQNWTSARPDRPAPVRSTPPAETAPKPAAETAVKRTSKYY
.
Mb1660|M.bovis_AF2122/97 LSRYLGTS----IVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVT
Rv1634|M.tuberculosis_H37Rv LSRYLGTS----IVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVT
Mflv_2746|M.gilvum_PYR-GCK FGHPIGLTNLFGVELWERFSFYGMLTILGYYLYYSVAEGGLGLPQATATG
Mvan_3792|M.vanbaalenii_PYR-1 FGHPVGLTNLFGVELWERFSFYGMLTILGYYLYYSVTDGGLGLPQSTATG
MSMEG_3533|M.smegmatis_MC2_155 FGHPMGLVNLFGVELWERFSFYGMLTILGYYLYYTATDGGLGLPQSTATG
MMAR_0690|M.marinum_M VLAAVGFT-----------FFIDMLVYGIVVPVLPRLAKPAGLEFLGVGV
MAB_1338|M.abscessus_ATCC_1997 TVRHDRRITPTPVSAWNRMRYWVIAHAVDDFYQGLVPAAIPFFVLERHYS
MAV_3702|M.avium_104 PAWLPSRRFIAAVIAIGGMQLLATMDSTVAIVALPRIQNELSLSDAGRSW
Mb1660|M.bovis_AF2122/97 TLYLVGSVVAATTVNTMLLR---VGARSSYLMGLAVFGLASLVCAAAPSM
Rv1634|M.tuberculosis_H37Rv TLYLVGSVVAATTVNTMLLR---VGARSSYLMGLAVFGLASLVCAAAPSM
Mflv_2746|M.gilvum_PYR-GCK IVGAYGGLVYLSTVLGGWIADRVLGMERTVFYGGVVVMLGHIALAVLPGL
Mvan_3792|M.vanbaalenii_PYR-1 IVGAYGGLVYLSTVLGGWIADRLLGMERTVFYGGVVVMLGHIALAILPGL
MSMEG_3533|M.smegmatis_MC2_155 IVGAYGGLVYLSTVLGGWIADRVLGMERTVFYGGVVVMCGHIALAVLPGL
MMAR_0690|M.marinum_M VFACYGLAYFVLTPVAGWLIDR-RGSRSVFLSGAIILMLATLAFGYASSP
MAB_1338|M.abscessus_ATCC_1997 YAAASG--LALAATLGSALPQPLLGLIADRWRLLWMAPAGLAAAGIGAGL
MAV_3702|M.avium_104 VITAYVLTFGGLMLLGGRLGDT-IGRKRTFIVGVALFTISSVLCAVAWDE
: * : . . .
Mb1660|M.bovis_AF2122/97 QILVAGRTLQG---IAGGLLAGLGYALINSTLPKS--LWTRGSALVSAMW
Rv1634|M.tuberculosis_H37Rv QILVAGRTLQG---IAGGLLAGLGYALINSTLPKS--LWTRGSALVSAMW
Mflv_2746|M.gilvum_PYR-GCK AGVGAGLVLVA---LGSGALKANASSLLGTLYAKGDPRADGGFTLFYLGI
Mvan_3792|M.vanbaalenii_PYR-1 TGVGVGLVLVA---LGSGALKANASSLLGTLYDKGDARADGGFTLFYLGI
MSMEG_3533|M.smegmatis_MC2_155 AGVGIGLVLVA---LGSGALKANASSLLGTLYDKDDPRCDGGFTLFYLGV
MMAR_0690|M.marinum_M VGLVTCRVLQG---GAAAATWVAGYATLVEIFPRE--QRGRAVGLASIGT
MAB_1338|M.abscessus_ATCC_1997 AGLVPGYWLVWTMLLVSGLGVAAFHPAAGRDARRDAGDSATAMSLFAAGG
MAV_3702|M.avium_104 ATMVIARLSQG---VGSAIASPTGLALVATTFPKG-PARNFATAVFAAMT
: .. . : . :
Mb1660|M.bovis_AF2122/97 GVATLIGPATGGLFAQLGLWRWAFGVMTL---LTALMAMLVPVALGAGRV
Rv1634|M.tuberculosis_H37Rv GVATLIGPATGGLFAQLGLWRWAFGVMTL---LTALMAMLVPVALGAGGV
Mflv_2746|M.gilvum_PYR-GCK NLGAFIGPLITGLLQTRVGFHYGFGAAAIGMALGLLQYVAFRRNLGEHGR
Mvan_3792|M.vanbaalenii_PYR-1 NLGAFIGPLITGLLQTRIGFHYGFGAAAIGMALGLIQYVVFRRNLGEHGR
MSMEG_3533|M.smegmatis_MC2_155 NLGAFVGPLVTGILQTRIGFHYGFGAAAIGMALGLVQYVVYRRNLGTHGR
MMAR_0690|M.marinum_M ALGALLGPALGGLAYEASGPHAPFLGAAG---LSALAVAALAASLPQAAG
MAB_1338|M.abscessus_ATCC_1997 SVGFFLAPALVTPALVSAGLGATAWFIPP---AVIMGFVLWRYQLRQGSA
MAV_3702|M.avium_104 AVGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMMYLARTALRETNRERMK
:. .:. . :
Mb1660|M.bovis_AF2122/97 GPGGETPVGSTHKVP--VWSLL-----LMGAAALAISVAALPNYLVQTAG
Rv1634|M.tuberculosis_H37Rv GPGGETPVGSTHKVP--VWSLL-----LMGAAALAISVAALPNYLVQTAG
Mflv_2746|M.gilvum_PYR-GCK EVPNPLPRGAIGKTASVFAVVV-----LVVAAAVALRLVTLENLSQVTTG
Mvan_3792|M.vanbaalenii_PYR-1 QVPNPLPRSAIGKTAGVFVAVI-----VVIAAAVALKLVTLANLSQVTTG
MSMEG_3533|M.smegmatis_MC2_155 IVPNPLPSSSFGKVAAFATALV-----IAAVALFVSGVVTLANLSQATTV
MMAR_0690|M.marinum_M GQASGPGMWSGERAFPGLAVPW-----LVAGLAVGLALGAVEATLPIDLV
MAB_1338|M.abscessus_ATCC_1997 NSVDRQLTGNDRWGAFSILVAV-----EVVRSAVYFGMNTFIALYLIDHL
MAV_3702|M.avium_104 LDATGAVLATLACTAAVFAFSMGPEKGWISLTTISSGVVALGAALAFVIV
. : :.
Mb1660|M.bovis_AF2122/97 LLAAAALLVAVFVVVDWRIHAAVLP-----PSVFGSGPLKWIYLTMSVQM
Rv1634|M.tuberculosis_H37Rv LLAAAALLVAVFVVVDWRIHAAVLP-----PSVFGSGPLKWIYLTMSVQM
Mflv_2746|M.gilvum_PYR-GCK VIVIASVAYFVVLFRSPKVTAPERIRVRAFIPLFVANAVFWSLFQQIFTV
Mvan_3792|M.vanbaalenii_PYR-1 VIIVASIGYFLIMLGSDKVSGPERVRLRAFIPLFVANAVFWSLFQQIFTV
MSMEG_3533|M.smegmatis_MC2_155 VIALASVAYFAVFLTSSKVSTLERTRVRAFIPLFVANAVFWSLFQQIFTV
MMAR_0690|M.marinum_M ARFDASGVTVGLLFALTTVAFIVTS-------------------------
MAB_1338|M.abscessus_ATCC_1997 DVSAAVGGVGLAMFLGG---------------------------------
MAV_3702|M.avium_104 ERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVMFTLTVCIGLYVQDILGY
..
Mb1660|M.bovis_AF2122/97 IAAMVDTYV--PLFG-----QRLGHLTPVAAGFLGAALAVGWTVGEVASA
Rv1634|M.tuberculosis_H37Rv IAAMVDTYV--PLFG-----QRLGHLTPVAAGFLGAALAVGWTVGEVASA
Mflv_2746|M.gilvum_PYR-GCK LAVYSDERMNWSIFGWTAPSNWIGSIEPIWIIALSPLFALMWTR--LGKR
Mvan_3792|M.vanbaalenii_PYR-1 LAVYSDERMNWSIFGWTAPSNWIGSIEPIWIIVLSPLFALMWTR--LGKR
MSMEG_3533|M.smegmatis_MC2_155 LAVYSDERMNWSVFGWTAPSNWIGSIEPVWIIVLSPVFAWLWTR--LGDR
MMAR_0690|M.marinum_M --------------------QYAGRLS--DAGRRAPVLAAGWVTLGVALA
MAB_1338|M.abscessus_ATCC_1997 --------------------GVIGTLLGGRISDRLGMIATIRVG-----S
MAV_3702|M.avium_104 SALRAGVGFIPFVIAMG---IGLGVSSQLVARFSPRVLTIAGGYLLVLAM
* ::
Mb1660|M.bovis_AF2122/97 SLNSARVIGHVVAAAPLVMASGLALGAVT---QRADAPVGIIALWALALL
Rv1634|M.tuberculosis_H37Rv SLNSARVIGHVVAAAPLVMASGLALGAVT---QRADAPVGIIALWALALL
Mflv_2746|M.gilvum_PYR-GCK APTTPRKFAYGVIGMGVAFLCFVPLAGVS--AVPALVVLAILGVFAVSEL
Mvan_3792|M.vanbaalenii_PYR-1 APTTPRKFAYGVIGMGLAFLCFVPLAGIT--AVPALLVMAVLGVFAVSEL
MSMEG_3533|M.smegmatis_MC2_155 APTTPRKFSYAVIGMGVAFLLFLPMAGTTGRAVPALVVAAILALFAISEL
MMAR_0690|M.marinum_M VMGVPSAVG--IQAAALVLLG----AGLG------AMIATIMPALADAME
MAB_1338|M.abscessus_ATCC_1997 IVAIPAFVALRICPQPWIALALAAVVGIT-----VNIPFAVLVKLGQDYL
MAV_3702|M.avium_104 LYGWWCMHRGVPYFPNLVLPIVVGGIGIG----MAVVPLTLSAIAGVGFD
. : .
Mb1660|M.bovis_AF2122/97 IIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAG
Rv1634|M.tuberculosis_H37Rv IIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAG
Mflv_2746|M.gilvum_PYR-GCK LLSP-IGLS-----------VTTKLAPQAFRAQMMALYFFSVGLGTSMSG
Mvan_3792|M.vanbaalenii_PYR-1 LLSP-IGLS-----------VTTKLAPEAFRAQMMALYFFSVGLGTSMSG
MSMEG_3533|M.smegmatis_MC2_155 TISP-IGLS-----------VTTKLAPEAFRAQMMALYFFSLGLGTAMSG
MMAR_0690|M.marinum_M SAGG-------------------AQRPGTAAAAYNLAFSAGTVAGGPLAG
MAB_1338|M.abscessus_ATCC_1997 PTRP-----------------------GTAAGVTLGLAVSIGGFFVPLLG
MAV_3702|M.avium_104 QIGPVSAVT----------LMLQSLGGPLVLAVIQAVITSRTLYLGGTTG
. *
Mb1660|M.bovis_AF2122/97 VVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR------
Rv1634|M.tuberculosis_H37Rv VVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR------
Mflv_2746|M.gilvum_PYR-GCK VLAGYYDTSREAAYFGVLGAIAVVAGVVVFAISPWISRQMEGVH------
Mvan_3792|M.vanbaalenii_PYR-1 VLARYYDPSREVAYFGILGGVAVAAGVIVFAIAPWISRQMEGVH------
MSMEG_3533|M.smegmatis_MC2_155 VLAGYYDPAHEFAYFGILGLVAIVVGIVVFAVSPRITRLMEGVH------
MMAR_0690|M.marinum_M WMADLRSFQDAAMLIAVVTLTCGVLAALVHAAVVRRAVSDA---------
MAB_1338|M.abscessus_ATCC_1997 VLADHHGPQAVLTTLCVAPILAIVLAFLLPHPERE---------------
MAV_3702|M.avium_104 PVKTMNDAQLQALDHGYTYGLLWVAGAAVIVGAAALFIGYTPEQVAHAQE
: . :
Mb1660|M.bovis_AF2122/97 ----------
Rv1634|M.tuberculosis_H37Rv ----------
Mflv_2746|M.gilvum_PYR-GCK ----------
Mvan_3792|M.vanbaalenii_PYR-1 ----------
MSMEG_3533|M.smegmatis_MC2_155 ----------
MMAR_0690|M.marinum_M ----------
MAB_1338|M.abscessus_ATCC_1997 ----------
MAV_3702|M.avium_104 VKEAMDAGEL