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TIREQGDRRTFFGHPVGLTNLFGVELWERFSFYGMLTILGYYLYYSVTDGGLGLPQSTATGIVGAYGGLV YLSTVLGGWIADRLLGMERTVFYGGVVVMLGHIALAILPGLTGVGVGLVLVALGSGALKANASSLLGTLY DKGDARADGGFTLFYLGINLGAFIGPLITGLLQTRIGFHYGFGAAAIGMALGLIQYVVFRRNLGEHGRQV PNPLPRSAIGKTAGVFVAVIVVIAAAVALKLVTLANLSQVTTGVIIVASIGYFLIMLGSDKVSGPERVRL RAFIPLFVANAVFWSLFQQIFTVLAVYSDERMNWSIFGWTAPSNWIGSIEPIWIIVLSPLFALMWTRLGK RAPTTPRKFAYGVIGMGLAFLCFVPLAGITAVPALLVMAVLGVFAVSELLLSPIGLSVTTKLAPEAFRAQ MMALYFFSVGLGTSMSGVLARYYDPSREVAYFGILGGVAVAAGVIVFAIAPWISRQMEGVH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3792 | - | - | 100% (482) | amino acid/peptide transporter |
| M. vanbaalenii PYR-1 | Mvan_4475 | - | 2e-05 | 23.12% (372) | Bcr/CflA subfamily drug resistance transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2746 | - | 0.0 | 86.93% (482) | amino acid/peptide transporter |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01562 | - | 2e-09 | 21.67% (383) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_1338 | - | 3e-07 | 31.17% (154) | putative membrane efflux protein |
| M. marinum M | MMAR_0690 | - | 3e-05 | 27.40% (219) | putative transport protein |
| M. avium 104 | MAV_2368 | - | 2e-05 | 24.05% (262) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_3533 | - | 0.0 | 79.83% (476) | di-/tripeptide transporter |
| M. thermoresistible (build 8) | TH_2729 | - | 1e-05 | 21.87% (439) | PUTATIVE putative drug resistance transporter, EmrB/QacA |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01562|M.leprae_Br4923 ---------MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKY
MAV_2368|M.avium_104 -----------------------------------MTMSVAPT-------
Mvan_3792|M.vanbaalenii_PYR-1 -------------------------------------MTIREQGDRRTFF
Mflv_2746|M.gilvum_PYR-GCK -------------------------------------MVTHQRDSTRTLF
MSMEG_3533|M.smegmatis_MC2_155 MPQNTLHTAGFPFAHRIAGFSALPADALTERGKVTPMGEAHDTQARRTVF
TH_2729|M.thermoresistible__bu --------------------------------------------------
MMAR_0690|M.marinum_M --------------------------------------------------
MAB_1338|M.abscessus_ATCC_1997 ---------------------------------------MTDLANDEQLT
MLBr_01562|M.leprae_Br4923 PTLLPSGRFPSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSD
MAV_2368|M.avium_104 ------TRLWSRQFVAVIVAIGGMQLMVAMDGPVAVFALPKIQNEMGLSD
Mvan_3792|M.vanbaalenii_PYR-1 GHPVGLTNLFGVELWERFSFYGMLTILG------YYLYYSVTDGGLGLPQ
Mflv_2746|M.gilvum_PYR-GCK GHPIGLTNLFGVELWERFSFYGMLTILG------YYLYYSVAEGGLGLPQ
MSMEG_3533|M.smegmatis_MC2_155 GHPMGLVNLFGVELWERFSFYGMLTILG------YYLYYTATDGGLGLPQ
TH_2729|M.thermoresistible__bu -------VLVALILTMALVAMDTTILAT---------AVPQVVGDLGGFD
MMAR_0690|M.marinum_M --------MTDSSRRVVLAAVGFTFFIDMLVYGIVVPVLPRLAKPAGLEF
MAB_1338|M.abscessus_ATCC_1997 VRHDRRITPTPVSAWNRMRYWVIAHAVDDFYQGLVPAAIPFFVLERHYSY
. .
MLBr_01562|M.leprae_Br4923 AGRSWGITAYVLTFGGLMLLGGRLGDTIGRKR-TFIVGVALFTISSVLCA
MAV_2368|M.avium_104 AARSWVITAYMLTFGGLMLLGGRLGDTIGRKRAAFLVGVALFTFASGLCG
Mvan_3792|M.vanbaalenii_PYR-1 STATGIVGAYGGLVYLSTVLGGWIADRLLGMERTVFYGGVVVMLGHIALA
Mflv_2746|M.gilvum_PYR-GCK ATATGIVGAYGGLVYLSTVLGGWIADRVLGMERTVFYGGVVVMLGHIALA
MSMEG_3533|M.smegmatis_MC2_155 STATGIVGAYGGLVYLSTVLGGWIADRVLGMERTVFYGGVVVMCGHIALA
TH_2729|M.thermoresistible__bu QVG-WVFSGYLLAQTVTIPIYGKLAD-LYGRRPILIFGVVAFLIGSALSA
MMAR_0690|M.marinum_M LGVGVVFACYGLAYFVLTPVAGWLID-RRGSRSVFLSGAIILMLATLAFG
MAB_1338|M.abscessus_ATCC_1997 AAASGLALAATLGSALPQPLLGLIAD-RWRLLWMAPAGLAAAGIGAGLAG
: * : * * . .
MLBr_01562|M.leprae_Br4923 VAWDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSAR-NTATAVFAA
MAV_2368|M.avium_104 IAWAGGTLIAARLLHGAAAAIIAPTNLALIATTFPRGSAR-NAATAVFGA
Mvan_3792|M.vanbaalenii_PYR-1 ILPGLTGVGVGLVLVALGSGALKANASSLLGTLYDKGDARADGGFTLFYL
Mflv_2746|M.gilvum_PYR-GCK VLPGLAGVGAGLVLVALGSGALKANASSLLGTLYAKGDPRADGGFTLFYL
MSMEG_3533|M.smegmatis_MC2_155 VLPGLAGVGIGLVLVALGSGALKANASSLLGTLYDKDDPRCDGGFTLFYL
TH_2729|M.thermoresistible__bu ASWNMATLAIFRAIQGLGAGAISATVQTVAGDLYTVAERG--RIQGYLAS
MMAR_0690|M.marinum_M YASSPVGLVTCRVLQGGAAAATWVAGYATLVEIFPREQRG--RAVGLASI
MAB_1338|M.abscessus_ATCC_1997 LVPGYWLVWTMLLVSGLGVAAFHP----AAGRDARRDAGDSATAMSLFAA
: : . . .
MLBr_01562|M.leprae_Br4923 MTAIGSVMGLVVGGALTE-VSWRLAFLVNVPIGLVMIYLARTALHETHKE
MAV_2368|M.avium_104 MTGLGGVLGLVVGGALTD-VSWRLAFLVNVPIGLAVIYLVLITRQETQTE
Mvan_3792|M.vanbaalenii_PYR-1 GINLGAFIGPLITGLLQT-RIGFHYGFGAAAIGMALGLIQYVVFRRNLGE
Mflv_2746|M.gilvum_PYR-GCK GINLGAFIGPLITGLLQT-RVGFHYGFGAAAIGMALGLLQYVAFRRNLGE
MSMEG_3533|M.smegmatis_MC2_155 GVNLGAFVGPLVTGILQT-RIGFHYGFGAAAIGMALGLVQYVVYRRNLGT
TH_2729|M.thermoresistible__bu VWGISAVIAPALGGFFAQYLTWRWIFLVNIPIGVFALYLIARDLHEDVVR
MMAR_0690|M.marinum_M GTALGALLGPALGGLAYEASGPHAPFLGAAGLSALAVAALAASLPQAAGG
MAB_1338|M.abscessus_ATCC_1997 GGSVGFFLAPALVTPALVSAGLGATAWFIPPAVIMGFVLWRYQLRQGSAN
:. .:. : .
MLBr_01562|M.leprae_Br4923 R-MKLDAAGAILATLACTAAVFAFSMG-PEKGWISLTTIGSGLVALVAAI
MAV_2368|M.avium_104 R-IKLDVTGAVLATVTGTAAVFGISMG-PEAGWRSPITIGSGVVALAAFV
Mvan_3792|M.vanbaalenii_PYR-1 H-GRQVPNPLPRSAIGKTAGVFVAVIV-VIAAAVALKLVTLANLSQVTTG
Mflv_2746|M.gilvum_PYR-GCK H-GREVPNPLPRGAIGKTASVFAVVVL-VVAAAVALRLVTLENLSQVTTG
MSMEG_3533|M.smegmatis_MC2_155 H-GRIVPNPLPSSSFGKVAAFATALVI-AAVALFVSGVVTLANLSQATTV
TH_2729|M.thermoresistible__bu RPHRIDYLGAGLVLVSAGLFILGLLSGGVHWSWTSPTSVVVFTGAALAGV
MMAR_0690|M.marinum_M Q-------ASGPGMWSGERAFPGLAVP----WLVAGLAVGLALGAVEATL
MAB_1338|M.abscessus_ATCC_1997 S---VDRQLTGNDRWGAFSILVAVEVV--------RSAVYFGMNTFIALY
. : : :
MLBr_01562|M.leprae_Br4923 AFAVVERTAENPVVPFDLFR--DRNRLVTFIAIFLAGGVIFSLTVSIGLY
MAV_2368|M.avium_104 AFVVVERTAENPIVPFNLFL--DRNRLAAFAAMFLAGGVFFTLTVLVGLY
Mvan_3792|M.vanbaalenii_PYR-1 VIIVASIGYFLIMLGSDKVSGPERVRLRAFIPLFVANAVFWSLFQQI---
Mflv_2746|M.gilvum_PYR-GCK VIVIASVAYFVVLFRSPKVTAPERIRVRAFIPLFVANAVFWSLFQQI---
MSMEG_3533|M.smegmatis_MC2_155 VIALASVAYFAVFLTSSKVSTLERTRVRAFIPLFVANAVFWSLFQQI---
TH_2729|M.thermoresistible__bu ALLVVESRAAEPVLPLSMLT--RRLTAPSFAATATAGMIVIGLSVYLPNW
MMAR_0690|M.marinum_M PIDLVAR-------------------------------------------
MAB_1338|M.abscessus_ATCC_1997 LIDHLDVS------------------------------------------
:
MLBr_01562|M.leprae_Br4923 IQDILGYSALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLL
MAV_2368|M.avium_104 VQTMMGYSPLRAGVAFIPFGLAMAIGVGVASKLVTWFPPRVVVIASGGLI
Mvan_3792|M.vanbaalenii_PYR-1 FTVLAVYSDERMNWSIFGWTAPSNWIGSIEPIWIIVLSP-LFALMWTRLG
Mflv_2746|M.gilvum_PYR-GCK FTVLAVYSDERMNWSIFGWTAPSNWIGSIEPIWIIALSP-LFALMWTRLG
MSMEG_3533|M.smegmatis_MC2_155 FTVLAVYSDERMNWSVFGWTAPSNWIGSIEPVWIIVLSP-VFAWLWTRLG
TH_2729|M.thermoresistible__bu GQTVLGLSPVAAGFVLAIMSITWPISSGFSARLYLRIGFRDTALVGASCA
MMAR_0690|M.marinum_M ----FDASGVTVGLLFALTTVAFIVTSQYAGRLS----------------
MAB_1338|M.abscessus_ATCC_1997 ----AAVGGVGLAMFLGGGVIGTLLGGRISDRLG----------------
. .
MLBr_01562|M.leprae_Br4923 MVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFD
MAV_2368|M.avium_104 LGATLYGSTFN-RGMPYFPNLVVPLIVCAIGIGAVFVTLTLSVIASVDVD
Mvan_3792|M.vanbaalenii_PYR-1 KRAPTTPRKFAYGVIGMGLAFLCFVPLAGIT--AVPALLVMAVLGVFAVS
Mflv_2746|M.gilvum_PYR-GCK KRAPTTPRKFAYGVIGMGVAFLCFVPLAGVS--AVPALVVLAILGVFAVS
MSMEG_3533|M.smegmatis_MC2_155 DRAPTTPRKFSYAVIGMGVAFLLFLPMAGTTGRAVPALVVAAILALFAIS
TH_2729|M.thermoresistible__bu VAAGTGLVLLGPAPPVWQPVVYTALMGAGMG--LLFSPLIVGLQNTVGWD
MMAR_0690|M.marinum_M -DAGRRAPVLAAGWVTLGVALAVMGVPSAVGIQAAALVLLGAGLGAMIAT
MAB_1338|M.abscessus_ATCC_1997 -------------MIATIRVGSIVAIPAFVALRICPQPWIALALAAVVGI
.
MLBr_01562|M.leprae_Br4923 RIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQL
MAV_2368|M.avium_104 RIGPTSAIAVMLQTLGGPLVLVVVQVAITSHALRLGGTLGPVKSMNAAQL
Mvan_3792|M.vanbaalenii_PYR-1 EL-LLSPIGLSVTTKLAPEAFRAQMMALYFFSVGLG------TSMSGVLA
Mflv_2746|M.gilvum_PYR-GCK EL-LLSPIGLSVTTKLAPQAFRAQMMALYFFSVGLG------TSMSGVLA
MSMEG_3533|M.smegmatis_MC2_155 EL-TISPIGLSVTTKLAPEAFRAQMMALYFFSLGLG------TAMSGVLA
TH_2729|M.thermoresistible__bu QRGTVTG-GLMFSRFLGQSIGAAGFGAVANAVLRRY----------EPDT
MMAR_0690|M.marinum_M IMPALADAMESAGGAQRPGTAAAAYNLAFSAGTVAG----------GPLA
MAB_1338|M.abscessus_ATCC_1997 TVNIPFAVLVKLGQDYLPTRPGTAAGVTLGLAVSIG-------GFFVPLL
.
MLBr_01562|M.leprae_Br4923 RALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL
MAV_2368|M.avium_104 HALDRGYTYGLLWLAGVVALLGGVTLLIGYTAAQVARAQEVKKAVDAGEL
Mvan_3792|M.vanbaalenii_PYR-1 RYYDPSREVAYFGILGGVAVAAGVIVFA--IAPWISRQMEGVH-------
Mflv_2746|M.gilvum_PYR-GCK GYYDTSREAAYFGVLGAIAVVAGVVVFA--ISPWISRQMEGVH-------
MSMEG_3533|M.smegmatis_MC2_155 GYYDPAHEFAYFGILGLVAIVVGIVVFA--VSPRITRLMEGVH-------
TH_2729|M.thermoresistible__bu SAAAMGAASHAVFVGLLVAAVATVVLLLTVPRRFPTHHVAVVD-------
MMAR_0690|M.marinum_M GWMADLRSFQDAAMLIAVVTLTCGVLAALVHAAVVRRAVSDA--------
MAB_1338|M.abscessus_ATCC_1997 GVLADHHGPQAVLTTLCVAPILAIVLAFLLPHPERE--------------
:. :