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M. gilvum PYR-GCK Mflv_1792 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 1865195 - 1866394
length: 399

MDFDMGKGAADLRRELRALVGEHVPEHFLGAFTDDPADLDTAQRFCRMLAERNLLCMAWPEEFGGSGASV
WEQTVVREEMWAHHEPRGAQYMGVNWVGPIIMRHGTEEQQRRHLPPIAAGEVIWCQGFSEPEAGSDLASL
RTYARADGDGWLVSGQKIWTSYATMAQWCFLLARTSRLGEGATQKKQQGLTIFLVPMDDPAITVRPIRTM
LGPHHLNEVFFDDLRVTEADVLGTVDQGWSIVQDVMSFERVGIARYARCERLLAAAPTVLGERWDSLPTE
LRGRWIRMLTHCRRARLLAYRVVALQSSGRIAPGDAAAYRIAVTKLDQDSAEVLMDIAAEVRHDDERAAW
FLGEVDDHWRYSQASTVSSGSIEMQRILLSRAMLTADARSKSASVGAPR

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_1792 - - 100% (399) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_1481 - 1e-50 35.65% (345) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_2287 - 2e-46 31.05% (380) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1969c fadE17 2e-51 32.83% (399) acyl-CoA dehydrogenase FADE17
M. tuberculosis H37Rv Rv1934c fadE17 2e-51 32.83% (399) acyl-CoA dehydrogenase FADE17
M. leprae Br4923 MLBr_00737 fadE25 2e-24 26.72% (393) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 1e-49 33.51% (376) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_3981 fadE17_2 1e-123 55.30% (387) acyl-CoA dehydrogenase FadE17_2
M. avium 104 MAV_1629 - 1e-127 56.88% (385) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_5622 - 0.0 79.74% (390) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3217 - 0.0 80.31% (391) PUTATIVE putative acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_3842 fadE17_2 1e-124 55.56% (387) acyl-CoA dehydrogenase FadE17_2
M. vanbaalenii PYR-1 Mvan_4958 - 0.0 92.05% (390) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1969c|M.bovis_AF2122/97           ---MDVSYPPEAEAF--------RDRIREFVAEHLPPGWPGPGAL--PPH
Rv1934c|M.tuberculosis_H37Rv        ---MDVSYPPEAEAF--------RDRIREFVAEHLPPGWPGPGAL--PPH
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
Mflv_1792|M.gilvum_PYR-GCK          ---MDFDMGKGAADL--------RRELRALVGEHVPEHFLG-----AFTD
Mvan_4958|M.vanbaalenii_PYR-1       ---MDFDMGKRASDL--------RRELRDLVNERVPERFLG-----AFTD
MSMEG_5622|M.smegmatis_MC2_155      ---MDFDLGEDANRL--------RGELRALIDAHVPADFLG-----AFTD
TH_3217|M.thermoresistible__bu      -MTLNFDMGADAARL--------RGELRQLIAEHVPAGYLG-----AFTD
MMAR_3981|M.marinum_M               ---MDYDLGDDARQL--------RDRLRRLISEHIPDDFLG-----ACTT
MUL_3842|M.ulcerans_Agy99           ---MDYDLGDDARQL--------RDRLRRLISEHIPDDFLG-----ACTT
MAV_1629|M.avium_104                ---MDYDLGDDAAQL--------RSHLRELVANHIPADFLG-----ACTE
MLBr_00737|M.leprae_Br4923          --MVGWSGNPLFDLFKLP---EEHNELRATIRALAEKEIAP-----HAAD
                                          .       :        : .:*  :                   

Mb1969c|M.bovis_AF2122/97           EREEFAR--HWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
Rv1934c|M.tuberculosis_H37Rv        EREEFAR--HWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
Mflv_1792|M.gilvum_PYR-GCK          DPADLDTAQRFCRMLAERNLLCMAWPEEFGGSGASVWEQTVVREEMWAHH
Mvan_4958|M.vanbaalenii_PYR-1       DPADLETAQAFCRTLAERNLLCLAWPEEFGGGGASVWEQTVVREEMWAHH
MSMEG_5622|M.smegmatis_MC2_155      DPADLAVAQQFCRTLAERQLLCMSWPREFGGGDASVWEQTVVREEMWAHH
TH_3217|M.thermoresistible__bu      DPADLEVAQQFCRTLAERNLLCLSWPSEYGGGDASVWEQTVVREEMWAHH
MMAR_3981|M.marinum_M               DPQDLATTESFCKLLAAEDLLALAWPKEHGGGGGSIWQQTVLREEMWARH
MUL_3842|M.ulcerans_Agy99           DPQDLATTESFCKLLAAEDLLALAWPEEHGGGGGSIWQQTVLREEMWARH
MAV_1629|M.avium_104                NPQDLATTETFCKLLAAEGLLALAWPKEHGGGGGSVWQQTVLREEMWAQH
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                                  *      .:  * *.** .       :. **     

Mb1969c|M.bovis_AF2122/97           APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
Rv1934c|M.tuberculosis_H37Rv        APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
MAB_0597|M.abscessus_ATCC_1997      APHKVN--HLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPG
Mflv_1792|M.gilvum_PYR-GCK          EPRGAQ--YMGVNWVGPIIMRHGTEEQQRRHLPPIAAGEVIWCQGFSEPE
Mvan_4958|M.vanbaalenii_PYR-1       EPRGAQ--YMGVNWVGPIIMRHGTEAQQLRHLPPIAAGEVIWCQGFSEPE
MSMEG_5622|M.smegmatis_MC2_155      EPRGAQ--YMGVNWVGPIIMRYGTEEQQRKHLPPIANGEVIWCQGFSEPE
TH_3217|M.thermoresistible__bu      EPRGAQ--YMGVNWVGPIIMRHGTEEQQRTHLPPIARGEVIWCQGFSEPE
MMAR_3981|M.marinum_M               EPRGPQ--YMGINWVGPAIMRYGTPAQKTQHLSAIAAGEVVWCQGFSEPE
MUL_3842|M.ulcerans_Agy99           EPRGPQ--YMGINWVGPAIMRYGTPAQKTRHLSAIAAGEVVWCQGFSEPE
MAV_1629|M.avium_104                EPRGPQ--YMGINWVGPALMRYGTEEQKTKHLAAIAAGDVIWCQGFSEPE
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMG--LILRGSEELKKQVLPSLAAEGAMASYALSERE
                                     .            :*  ::  *:   :   *. :       . . **  

Mb1969c|M.bovis_AF2122/97           AGSDLASVRTRGVLDGDE---WVINGHKIWTSAGTTANWIFLLARTDPS-
Rv1934c|M.tuberculosis_H37Rv        AGSDLASVRTRGVLDGDE---WVINGHKIWTSAGTTANWIFLLARTDPS-
MAB_0597|M.abscessus_ATCC_1997      AGSDLANVSTSAVLDGGD---WVINGQKVWTSLALQSQWCFVVARTEPG-
Mflv_1792|M.gilvum_PYR-GCK          AGSDLASLRTYAR--ADGD-GWLVSGQKIWTSYATMAQWCFLLARTSRLG
Mvan_4958|M.vanbaalenii_PYR-1       AGSDLASLRTYARRAEDGD-GWLVSGQKIWTSYATMAQWCFLLARTSRVG
MSMEG_5622|M.smegmatis_MC2_155      AGSDLASLRTSARRVDD---GWRINGQKIWTSYATMAQWCFLLARTSKG-
TH_3217|M.thermoresistible__bu      AGSDLASLRTFARRAGDNPTGWLVNGQKIWTSYATMAQWCFLLARTTRVG
MMAR_3981|M.marinum_M               AGTDLASLRTRAVPEAPDGPGWRITGQKVWTSYAQMASWCVLAACTHPD-
MUL_3842|M.ulcerans_Agy99           AGTDLASLRTRAVPEAPDGPGWRITGQKVWTSYAQMASWCVLAACTHPD-
MAV_1629|M.avium_104                AGTDLVSLRTRAV---ADGDGWRITGQKVWTSYALMASWCVLAACTDPD-
MLBr_00737|M.leprae_Br4923          AGSDAASMRTRAKADGDD---WILNGFKCWITNGGKSTWYTVMAVTDPD-
                                    **:* ..: * .         * :.* * * : .  : *  : * *    

Mb1969c|M.bovis_AF2122/97           ----AAKHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTS
Rv1934c|M.tuberculosis_H37Rv        ----AAKHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTS
MAB_0597|M.abscessus_ATCC_1997      ----SSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTS
Mflv_1792|M.gilvum_PYR-GCK          EGATQKKQQGLTIFLVPMDDPAITVRPIRTMLGP--HHLNEVFFDDLRVT
Mvan_4958|M.vanbaalenii_PYR-1       EGATQKKQQGLTIFLVPMDDPAITVRPIRTMLGP--HHLNEVFFDDLRVT
MSMEG_5622|M.smegmatis_MC2_155      ----EKKQQGLTIFLVSMDDPAITVRPIRTMMGP--HHLNEVFFDDLEVT
TH_3217|M.thermoresistible__bu      DGGVQRKQQGLTVFLVPMDRPGIQVRPIRTMMGP--HHLNEVFFDDVPVT
MMAR_3981|M.marinum_M               ----APKPKRLTLFLLPMDRPGFTVRPIPSMLGP--HHLNEMFLDEVPAS
MUL_3842|M.ulcerans_Agy99           ----ARKPKRLTLFLLPMDRPGFTVRPIPSMLGP--HHLNEMFLDEVPAS
MAV_1629|M.avium_104                ----APKHKRLTLFLIPMDRPGFTVRPIPSMLGP--HHLNEMFLDDVPAY
MLBr_00737|M.leprae_Br4923          -----KGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIP
                                            . :: :::  *  .. : *     *      .*::: .    

Mb1969c|M.bovis_AF2122/97           AGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDRGL
Rv1934c|M.tuberculosis_H37Rv        AGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDRGL
MAB_0597|M.abscessus_ATCC_1997      ADLVVGEPGDGWRVAMGTLTFERGVSTLGNQITYARELSRLAELAKSNGA
Mflv_1792|M.gilvum_PYR-GCK          EADVLGTVDQGWSIVQDVMSFER--VGIARYARCERLLAAAPTVLGERWD
Mvan_4958|M.vanbaalenii_PYR-1       EADVLGTVDAGWSIVQDVMAFER--VGIARYARCERLLAAAPGVLGDRWD
MSMEG_5622|M.smegmatis_MC2_155      EADVLGTVDEGWKIVQDVVSFER--VGIARYARCERLLQAAPDVLGDAWD
TH_3217|M.thermoresistible__bu      EADVLGTVDDGWSIVQDVMSFER--VGIARYARCERLLALAPQVLGEHWD
MMAR_3981|M.marinum_M               PTDVLGEPGDGWRVMREALAFER--VGIARYARCESLLDRMRTELGDDWA
MUL_3842|M.ulcerans_Agy99           PSDVLGEPGDGWRVMREALAFER--VGIARYARCESLLDRMRTELGDDWA
MAV_1629|M.avium_104                PGDVLGEVGDGWRVMREALAYER--VGIARYARCESLLERMRGRLGDEWE
MLBr_00737|M.leprae_Br4923          GDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ
                                       ::*  . *:      : . *              *        .   

Mb1969c|M.bovis_AF2122/97           HTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITKVIWSE
Rv1934c|M.tuberculosis_H37Rv        HTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITKVIWSE
MAB_0597|M.abscessus_ATCC_1997      ADDPAIRERLAQAYVGMRTMR-----AYALATMDEERPGQDNVSKLLWAN
Mflv_1792|M.gilvum_PYR-GCK          SLPTELRGRWIRMLTHCRRARLLAYRVVALQSSGRIAPGDAAAYRIAVTK
Mvan_4958|M.vanbaalenii_PYR-1       SLPAELRGRWIGMLTHCRRARLLAYRVVALQSSGRITPGDASAYRIAVTK
MSMEG_5622|M.smegmatis_MC2_155      QLPAELRGRWTRMLTHCRRARLMAYRVVAMQATGRVNPGDSAAYRIAVTR
TH_3217|M.thermoresistible__bu      ALPAELHGRWARMLTHCRRARLLAYRVVALQAGGQVRPGDAAAYRIAVTR
MMAR_3981|M.marinum_M               RLPESIRVRWVRALADLRVARLLAYRAVALRDD-PTAGAAASAARIVTTT
MUL_3842|M.ulcerans_Agy99           RLPESSRVRWVRALADLRVARLLAYRAVALRDD-PTSGAAASAARIVTTT
MAV_1629|M.avium_104                QLPESIRARWVRALVDLRVARLLAYRAVSLQDD-PASGAAASAARIATTT
MLBr_00737|M.leprae_Br4923          FGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLG-FISAA
                                                        :                 .      .  : 

Mb1969c|M.bovis_AF2122/97           YFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYA
Rv1934c|M.tuberculosis_H37Rv        YFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYA
MAB_0597|M.abscessus_ATCC_1997      WHRDLGELAMEIIG------------TSTLLTNAGEMDE---WQRLFLFS
Mflv_1792|M.gilvum_PYR-GCK          LDQDSAEVLMDIAAEVRHDD----ERAAWFLGEV---------DDHWRYS
Mvan_4958|M.vanbaalenii_PYR-1       LDQDSAEVLMDIAAEVRRDD----HRAQWFLGEV---------EDHWRYS
MSMEG_5622|M.smegmatis_MC2_155      LDQESAEVLMEIAAALPRGG---DQRTEYFRAEV---------EDHWRYS
TH_3217|M.thermoresistible__bu      LDQDSAEVLMELVAALPPGDSADRQAAEYFRAEV---------EDHWRYS
MMAR_3981|M.marinum_M               CDQQVAELLLDVLGPAALDS----GTTAPLHGAI---------EDHWRYA
MUL_3842|M.ulcerans_Agy99           CDQQVAELLLDVLGPAALDS----GATAPLHGAI---------EDHWRYA
MAV_1629|M.avium_104                CDQQVAELLFDVLGPTALDA----GSGAPLHGAI---------EDHWRYA
MLBr_00737|M.leprae_Br4923          SKCFASDIAMEVTTDAVQLFG-----GAGYTSDFP-------VERFMRDA
                                          :: .::                                     :

Mb1969c|M.bovis_AF2122/97           RAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC---
Rv1934c|M.tuberculosis_H37Rv        RAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC---
MAB_0597|M.abscessus_ATCC_1997      RADTIYGGSNEIQRNIISERVLGLPREAR--------
Mflv_1792|M.gilvum_PYR-GCK          QASTVSSGSIEMQRILLSRAMLTADARSKSASVGAPR
Mvan_4958|M.vanbaalenii_PYR-1       QASTVSSGSIEMQRILLSRAMLSAGAAK---------
MSMEG_5622|M.smegmatis_MC2_155      QASTVSSGSIEMQRILLSRTMFAG--AAR--------
TH_3217|M.thermoresistible__bu      QASTVSSGSIEMQRILLSRAMLATGKAPR--------
MMAR_3981|M.marinum_M               QAATVASGTIEVQRMLVARDVLGEHR-----------
MUL_3842|M.ulcerans_Agy99           QAATVASGTIEVQRMLVARDVLGEHR-----------
MAV_1629|M.avium_104                QAATVASGTIEVQKMLVARDVLGGHR-----------
MLBr_00737|M.leprae_Br4923          KITQIYEGTNQIQRVVMSRALLR--------------
                                    :   :  *: ::*: ::.. ::

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_1792	-	-	100% (399)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_1481	-	1e-50	35.65% (345)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_2287	-	2e-46	31.05% (380)	acyl-CoA dehydrogenase domain-containing protein