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M. gilvum PYR-GCK Mflv_1481 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 1543764 - 1544912
length: 382

VIEVQKFRAEVRDWLAENLVGDFAALKGLGGPGREHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSV
AHRVAFYEEYAKANAPDKVNHLGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPGAGSDLANV
STTATLDGDEWVINGQKVWTSLAHWAQWCFVVARTEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGDSE
FNEVFFDDARTAADLVVGEPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAEKTGAADDPLIRE
RLVRSWAGLKAMRSYALATMDVEKPGQDNISKLLWANWHRELGEIAMDIEGAAGLTLPDGEFSEWQRLYL
FSRSDTIYGGSNEIQRNIIAERVLGLPREARH

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_1481 - - 100% (382) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_1479 - 2e-68 38.48% (382) acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK Mflv_1794 - 6e-62 38.44% (398) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 0.0 83.51% (382) acyl-CoA dehydrogenase FADE30
M. tuberculosis H37Rv Rv3560c fadE30 0.0 83.51% (382) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 5e-24 27.89% (355) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 0.0 81.02% (374) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5049 fadE30 0.0 85.75% (379) acyl-CoA dehydrogenase FadE30
M. avium 104 MAV_0601 - 0.0 85.49% (379) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_6012 - 0.0 88.24% (391) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4263 - 0.0 87.66% (381) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_4125 fadE30 0.0 85.22% (379) acyl-CoA dehydrogenase FadE30
M. vanbaalenii PYR-1 Mvan_5285 - 0.0 93.73% (383) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
MMAR_5049|M.marinum_M               --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MUL_4125|M.ulcerans_Agy99           --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MAV_0601|M.avium_104                --------------MQDV--EEFRAEVRSWLADNLVGEFAALKGLGGPGR
Mflv_1481|M.gilvum_PYR-GCK          --------------MIEV--QKFRAEVRDWLAENLVGDFAALKGLGGPGR
Mvan_5285|M.vanbaalenii_PYR-1       --------------MIEV--QEFRAEVRDWLAENLVGEYAALKGLGGPGR
MSMEG_6012|M.smegmatis_MC2_155      --------------MIEV--QEFRAEVRQWLADNLVGDFAALKGLGGPGR
TH_4263|M.thermoresistible__bu      --------------VIEV--HEFRAEVRQWLADNLVGEYAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MLBr_00737|M.leprae_Br4923          ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
                                                    :   . .:   .           *  :    .. 

Mb3590c|M.bovis_AF2122/97           EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv        EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
MMAR_5049|M.marinum_M               EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MUL_4125|M.ulcerans_Agy99           EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MAV_0601|M.avium_104                EHEAFEERRAWNQHLAKAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
Mflv_1481|M.gilvum_PYR-GCK          EHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
Mvan_5285|M.vanbaalenii_PYR-1       EHEAFEERLAWNRHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
MSMEG_6012|M.smegmatis_MC2_155      EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYARAN
TH_4263|M.thermoresistible__bu      EHEAFEERLEWNRKLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYALAN
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                     .:  .        *  :* ..:  * *:**:*        . ** * .:

Mb3590c|M.bovis_AF2122/97           APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
Rv3560c|M.tuberculosis_H37Rv        APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
MMAR_5049|M.marinum_M               APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MUL_4125|M.ulcerans_Agy99           APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MAV_0601|M.avium_104                APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
Mflv_1481|M.gilvum_PYR-GCK          APDKVNHLGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPGAG
Mvan_5285|M.vanbaalenii_PYR-1       APDKVNHLGEELLGPTLIAYGTPEQQQRFLPKILDVTELWSQGYSEPGAG
MSMEG_6012|M.smegmatis_MC2_155      APDKVNHFGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEPNAG
TH_4263|M.thermoresistible__bu      APAKVNHLGEELLGPTLIEYGTPEQQQRFLPRILDVTELWAQGYSEPGAG
MAB_0597|M.abscessus_ATCC_1997      APHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGAG
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
                                    *. .:    ::*    **  *: : :::.** :     : . . **  **

Mb3590c|M.bovis_AF2122/97           SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
Rv3560c|M.tuberculosis_H37Rv        SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
MMAR_5049|M.marinum_M               SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MUL_4125|M.ulcerans_Agy99           SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MAV_0601|M.avium_104                SDLANVSTTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
Mflv_1481|M.gilvum_PYR-GCK          SDLANVSTTATLD----------GDEWVINGQKVWTSLAHWAQWCFVVAR
Mvan_5285|M.vanbaalenii_PYR-1       SDLANVSTTAVLDE--------EGRQWHINGQKVWTSLAHWAQWCFVVAR
MSMEG_6012|M.smegmatis_MC2_155      SDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFVVAR
TH_4263|M.thermoresistible__bu      SDLANVSTTAVLD----------GDQWVINGQKVWTSLAHWAQWCFVVAR
MAB_0597|M.abscessus_ATCC_1997      SDLANVSTSAVLD----------GGDWVINGQKVWTSLALQSQWCFVVAR
MLBr_00737|M.leprae_Br4923          SDAASMRTRAKAD----------GDDWILNGFKCWITNGGKSTWYTVMAV
                                    ** *.: * *             .  * :** * * : .  : *  *:* 

Mb3590c|M.bovis_AF2122/97           TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Rv3560c|M.tuberculosis_H37Rv        TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MMAR_5049|M.marinum_M               TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MUL_4125|M.ulcerans_Agy99           TEKGSKRHAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDARTD
MAV_0601|M.avium_104                TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Mflv_1481|M.gilvum_PYR-GCK          TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTA
Mvan_5285|M.vanbaalenii_PYR-1       TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTD
MSMEG_6012|M.smegmatis_MC2_155      TEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGD--SEFNEVFFDDARTE
TH_4263|M.thermoresistible__bu      TERGSKRHHGLSYLLVPLDQPGVEIRPIVQLTGD--SEFNEVFFDNARTD
MAB_0597|M.abscessus_ATCC_1997      TEPGSSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTS
MLBr_00737|M.leprae_Br4923          TDP-DKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIP
                                    *:  ..   *:* ::*  :: ...* *  :  *   :  .*::**..*  

Mb3590c|M.bovis_AF2122/97           ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVELARR
Rv3560c|M.tuberculosis_H37Rv        ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVELARR
MMAR_5049|M.marinum_M               ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAALARR
MUL_4125|M.ulcerans_Agy99           ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAALARR
MAV_0601|M.avium_104                ASMVVGQPGDGWRVAMGTLTFER---GVSTLGQQIRYARELSNLAELARR
Mflv_1481|M.gilvum_PYR-GCK          ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAEK
Mvan_5285|M.vanbaalenii_PYR-1       ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAKR
MSMEG_6012|M.smegmatis_MC2_155      AGLVVGQPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAKR
TH_4263|M.thermoresistible__bu      ASMVVGEPGDGWRVAMGTLTFER---GVSTLGQQIQYRRELEGVVELAKR
MAB_0597|M.abscessus_ATCC_1997      ADLVVGEPGDGWRVAMGTLTFER---GVSTLGNQITYARELSRLAELAKS
MLBr_00737|M.leprae_Br4923          GDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ
                                    .. ::* ** *::.*:.** . *   *..::*            .   . 

Mb3590c|M.bovis_AF2122/97           TAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWA
Rv3560c|M.tuberculosis_H37Rv        TAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWA
MMAR_5049|M.marinum_M               TGAADDPFIRERLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
MUL_4125|M.ulcerans_Agy99           TGAADDPFIREHLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
MAV_0601|M.avium_104                NGAADDPFIRERLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
Mflv_1481|M.gilvum_PYR-GCK          TGAADDPLIRERLVRSWAGLKAMRSYALATMD---VEKPGQDNISKLLWA
Mvan_5285|M.vanbaalenii_PYR-1       TGAADDPLIRERLTRSWAGLKAMRSYALATMD---VEQPGMDNVSKLLWA
MSMEG_6012|M.smegmatis_MC2_155      TGAADDPLIRERLVQSWTGLQAMRSYALATMD---VEQPGQDNVSKLLWA
TH_4263|M.thermoresistible__bu      TGAIDDPLIRERLTRSWVGLRTMRSYALATMD---DERPGQDNISKLLWA
MAB_0597|M.abscessus_ATCC_1997      NGAADDPAIRERLAQAYVGMRTMRAYALATMD---EERPGQDNVSKLLWA
MLBr_00737|M.leprae_Br4923          FGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPD--LGFISA
                                     .   ..    ::  :  .::.  :  :.       *:   *    :: *

Mb3590c|M.bovis_AF2122/97           NWHRNLGELAMDVIGKPGMTMPDGEFD---EWQRLYLFTRADTIYGGSNE
Rv3560c|M.tuberculosis_H37Rv        NWHRNLGELAMDVIGKPGMTMPDGEFD---EWQRLYLFTRADTIYGGSNE
MMAR_5049|M.marinum_M               NWHRSLGELAMDVIGKPGLTLADGEFD---EWQRLFLFTRADTIYGGSNE
MUL_4125|M.ulcerans_Agy99           NWHRSLGELAMDVIGKPGLTLADGEFD---EWQRLFLFTRADTIYGGSNE
MAV_0601|M.avium_104                NWHRALGELAMDVIGKPGMTMPDGEFD---EWQRLFLFTRADTIYGGSNE
Mflv_1481|M.gilvum_PYR-GCK          NWHRELGEIAMDIEGAAGLTLPDGEFS---EWQRLYLFSRSDTIYGGSNE
Mvan_5285|M.vanbaalenii_PYR-1       NWHRELGEIAMDVQGMAGLTLPGGEFD---EWQRLYLFSRSDTIYGGSNE
MSMEG_6012|M.smegmatis_MC2_155      NWHRELGEIAMDVQGMAGLTLENGEFD---EWQRLYLFSRADTIYGGSNE
TH_4263|M.thermoresistible__bu      NWHRELGEIAMDVVGMAGLTLTDGDFD---EWQRLYLFSRSDTIYGGSNE
MAB_0597|M.abscessus_ATCC_1997      NWHRDLGELAMEIIGTSTLLTNAGEMD---EWQRLFLFSRADTIYGGSNE
MLBr_00737|M.leprae_Br4923          ASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQ
                                      :   .::**::   .      .        :*:   ::   ** *:*:

Mb3590c|M.bovis_AF2122/97           IQRNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv        IQRNIIAERVLGLPREAKG
MMAR_5049|M.marinum_M               IQRNIIAERVLGLPREAKG
MUL_4125|M.ulcerans_Agy99           IQRNIIAERVLGLPREAKG
MAV_0601|M.avium_104                IQRNIIAERVLGLPREVKG
Mflv_1481|M.gilvum_PYR-GCK          IQRNIIAERVLGLPREARH
Mvan_5285|M.vanbaalenii_PYR-1       IQRNIIAERVLGLPREAKG
MSMEG_6012|M.smegmatis_MC2_155      IQRNIIAERVLGLPREVKG
TH_4263|M.thermoresistible__bu      IQRNIIAERVLGLPREPKG
MAB_0597|M.abscessus_ATCC_1997      IQRNIISERVLGLPREAR-
MLBr_00737|M.leprae_Br4923          IQRVVMSRALLR-------
                                    *** :::. :*

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_1481	-	-	100% (382)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_1479	-	2e-68	38.48% (382)	acyl-CoA dehydrogenase domain-containing protein
M. gilvum PYR-GCK	Mflv_1794	-	6e-62	38.44% (398)	acyl-CoA dehydrogenase domain-containing protein