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DFDLGEDANRLRGELRALIDAHVPADFLGAFTDDPADLAVAQQFCRTLAERQLLCMSWPREFGGGDASVW EQTVVREEMWAHHEPRGAQYMGVNWVGPIIMRYGTEEQQRKHLPPIANGEVIWCQGFSEPEAGSDLASLR TSARRVDDGWRINGQKIWTSYATMAQWCFLLARTSKGEKKQQGLTIFLVSMDDPAITVRPIRTMMGPHHL NEVFFDDLEVTEADVLGTVDEGWKIVQDVVSFERVGIARYARCERLLQAAPDVLGDAWDQLPAELRGRWT RMLTHCRRARLMAYRVVAMQATGRVNPGDSAAYRIAVTRLDQESAEVLMEIAAALPRGGDQRTEYFRAEV EDHWRYSQASTVSSGSIEMQRILLSRTMFAGAAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5622 | - | - | 100% (385) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6012 | - | 1e-50 | 33.08% (393) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5619 | - | 5e-49 | 33.16% (383) | acyl-CoA dehydrogenase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1969c | fadE17 | 2e-51 | 33.84% (396) | acyl-CoA dehydrogenase FADE17 |
| M. gilvum PYR-GCK | Mflv_1792 | - | 0.0 | 79.74% (390) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1934c | fadE17 | 2e-51 | 33.84% (396) | acyl-CoA dehydrogenase FADE17 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-19 | 25.06% (391) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0595c | - | 5e-49 | 31.32% (380) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_3981 | fadE17_2 | 1e-122 | 55.50% (382) | acyl-CoA dehydrogenase FadE17_2 |
| M. avium 104 | MAV_1629 | - | 1e-127 | 55.99% (384) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3217 | - | 0.0 | 81.38% (392) | PUTATIVE putative acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_3842 | fadE17_2 | 1e-122 | 55.50% (382) | acyl-CoA dehydrogenase FadE17_2 |
| M. vanbaalenii PYR-1 | Mvan_4958 | - | 0.0 | 79.13% (393) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1969c|M.bovis_AF2122/97 ----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPPHERE
Rv1934c|M.tuberculosis_H37Rv ----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPPHERE
MAB_0595c|M.abscessus_ATCC_199 ----------MDLLLDDETEAFRAEVREFLVSNVPN--PPLPSYDSPEGA
MSMEG_5622|M.smegmatis_MC2_155 ----------MDFDLGEDANRLRGELRALIDAHVPADFLGAFTDDPAD-L
TH_3217|M.thermoresistible__bu --------MTLNFDMGADAARLRGELRQLIAEHVPAGYLGAFTDDPAD-L
Mflv_1792|M.gilvum_PYR-GCK ----------MDFDMGKGAADLRRELRALVGEHVPEHFLGAFTDDPAD-L
Mvan_4958|M.vanbaalenii_PYR-1 ----------MDFDMGKRASDLRRELRDLVNERVPERFLGAFTDDPAD-L
MMAR_3981|M.marinum_M ----------MDYDLGDDARQLRDRLRRLISEHIPDDFLGACTTDPQD-L
MUL_3842|M.ulcerans_Agy99 ----------MDYDLGDDARQLRDRLRRLISEHIPDDFLGACTTDPQD-L
MAV_1629|M.avium_104 ----------MDYDLGDDAAQLRSHLRELVANHIPADFLGACTENPQD-L
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP-----HAADVDQRA
:* :* : .:. : :
Mb1969c|M.bovis_AF2122/97 EFARHWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAGAPERA
Rv1934c|M.tuberculosis_H37Rv EFARHWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAGAPERA
MAB_0595c|M.abscessus_ATCC_199 AAHRQWERTLYDAGFSAVSWPKEYGGRDVTPLQWVIFEEEYFKAGAPARI
MSMEG_5622|M.smegmatis_MC2_155 AVAQQFCRTLAERQLLCMSWPREFGGGDASVWEQTVVREEMWAHHEPR--
TH_3217|M.thermoresistible__bu EVAQQFCRTLAERNLLCLSWPSEYGGGDASVWEQTVVREEMWAHHEPR--
Mflv_1792|M.gilvum_PYR-GCK DTAQRFCRMLAERNLLCMAWPEEFGGSGASVWEQTVVREEMWAHHEPR--
Mvan_4958|M.vanbaalenii_PYR-1 ETAQAFCRTLAERNLLCLAWPEEFGGGGASVWEQTVVREEMWAHHEPR--
MMAR_3981|M.marinum_M ATTESFCKLLAAEDLLALAWPKEHGGGGGSIWQQTVLREEMWARHEPR--
MUL_3842|M.ulcerans_Agy99 ATTESFCKLLAAEDLLALAWPEEHGGGGGSIWQQTVLREEMWARHEPR--
MAV_1629|M.avium_104 ATTETFCKLLAAEGLLALAWPKEHGGGGGSVWQQTVLREEMWAQHEPR--
MLBr_00737|M.leprae_Br4923 RFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASL
. * : .: * *.** . :. ** .
Mb1969c|M.bovis_AF2122/97 ENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPEAGSDL
Rv1934c|M.tuberculosis_H37Rv ENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPEAGSDL
MAB_0595c|M.abscessus_ATCC_199 SQN--GMFLLGPTLFAHGSKDQLDRVLPKMANGEEIWAQAWSEPESGSDL
MSMEG_5622|M.smegmatis_MC2_155 GAQYMGVNWVGPIIMRYGTEEQQRKHLPPIANGEVIWCQGFSEPEAGSDL
TH_3217|M.thermoresistible__bu GAQYMGVNWVGPIIMRHGTEEQQRTHLPPIARGEVIWCQGFSEPEAGSDL
Mflv_1792|M.gilvum_PYR-GCK GAQYMGVNWVGPIIMRHGTEEQQRRHLPPIAAGEVIWCQGFSEPEAGSDL
Mvan_4958|M.vanbaalenii_PYR-1 GAQYMGVNWVGPIIMRHGTEAQQLRHLPPIAAGEVIWCQGFSEPEAGSDL
MMAR_3981|M.marinum_M GPQYMGINWVGPAIMRYGTPAQKTQHLSAIAAGEVVWCQGFSEPEAGTDL
MUL_3842|M.ulcerans_Agy99 GPQYMGINWVGPAIMRYGTPAQKTRHLSAIAAGEVVWCQGFSEPEAGTDL
MAV_1629|M.avium_104 GPQYMGINWVGPALMRYGTEEQKTKHLAAIAAGDVIWCQGFSEPEAGTDL
MLBr_00737|M.leprae_Br4923 IPAVNKLGTMG--LILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDA
: :* :: *: *. : . . ** *:*:*
Mb1969c|M.bovis_AF2122/97 ASVRTRGVLDGD---EWVINGHKIWTSAGTTANWIFLLARTDPS-----A
Rv1934c|M.tuberculosis_H37Rv ASVRTRGVLDGD---EWVINGHKIWTSAGTTANWIFLLARTDPS-----A
MAB_0595c|M.abscessus_ATCC_199 ASLRSPARKVDG---GWRLSGQKIWSSRAPFADRAFGLFRSDPD-----A
MSMEG_5622|M.smegmatis_MC2_155 ASLRTSARRVDD---GWRINGQKIWTSYATMAQWCFLLARTSKG-----E
TH_3217|M.thermoresistible__bu ASLRTFARRAGDNPTGWLVNGQKIWTSYATMAQWCFLLARTTRVGDGGVQ
Mflv_1792|M.gilvum_PYR-GCK ASLRTYAR--ADGD-GWLVSGQKIWTSYATMAQWCFLLARTSRLGEGATQ
Mvan_4958|M.vanbaalenii_PYR-1 ASLRTYARRAEDGD-GWLVSGQKIWTSYATMAQWCFLLARTSRVGEGATQ
MMAR_3981|M.marinum_M ASLRTRAVPEAPDGPGWRITGQKVWTSYAQMASWCVLAACTHPD-----A
MUL_3842|M.ulcerans_Agy99 ASLRTRAVPEAPDGPGWRITGQKVWTSYAQMASWCVLAACTHPD-----A
MAV_1629|M.avium_104 VSLRTRAV---ADGDGWRITGQKVWTSYALMASWCVLAACTDPD-----A
MLBr_00737|M.leprae_Br4923 ASMRTRAKADGD---DWILNGFKCWITNGGKSTWYTVMAVTDPD------
.*:*: . * :.* * * : . : :
Mb1969c|M.bovis_AF2122/97 AKHRGLSFLLVPMDQPGVVVRPIVNAAGHSS--FSEVFLTDARTSAGNVV
Rv1934c|M.tuberculosis_H37Rv AKHRGLSFLLVPMDQPGVVVRPIVNAAGHSS--FSEVFLTDARTSAGNVV
MAB_0595c|M.abscessus_ATCC_199 QRHQGLTYFMFDLKAEGITVRPIPQLDGDPG--FAEIFLDDVFVPDEDVI
MSMEG_5622|M.smegmatis_MC2_155 KKQQGLTIFLVSMDDPAITVRPIRTMMGPHH--LNEVFFDDLEVTEADVL
TH_3217|M.thermoresistible__bu RKQQGLTVFLVPMDRPGIQVRPIRTMMGPHH--LNEVFFDDVPVTEADVL
Mflv_1792|M.gilvum_PYR-GCK KKQQGLTIFLVPMDDPAITVRPIRTMLGPHH--LNEVFFDDLRVTEADVL
Mvan_4958|M.vanbaalenii_PYR-1 KKQQGLTIFLVPMDDPAITVRPIRTMLGPHH--LNEVFFDDLRVTEADVL
MMAR_3981|M.marinum_M PKPKRLTLFLLPMDRPGFTVRPIPSMLGPHH--LNEMFLDEVPASPTDVL
MUL_3842|M.ulcerans_Agy99 RKPKRLTLFLLPMDRPGFTVRPIPSMLGPHH--LNEMFLDEVPASPSDVL
MAV_1629|M.avium_104 PKHKRLTLFLIPMDRPGFTVRPIPSMLGPHH--LNEMFLDDVPAYPGDVL
MLBr_00737|M.leprae_Br4923 KGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRII
. :: ::. . .. : * * *::: . ::
Mb1969c|M.bovis_AF2122/97 GRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDRGLHTDPR
Rv1934c|M.tuberculosis_H37Rv GRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDRGLHTDPR
MAB_0595c|M.abscessus_ATCC_199 GAVHDGWRVAMSTSSNERGMSLRSPGR-FLATADRLVELWKS--VPENEF
MSMEG_5622|M.smegmatis_MC2_155 GTVDEGWKIVQDVVSFERVGIARYARCERLLQAAPDVLGDAWDQLPAE--
TH_3217|M.thermoresistible__bu GTVDDGWSIVQDVMSFERVGIARYARCERLLALAPQVLGEHWDALPAE--
Mflv_1792|M.gilvum_PYR-GCK GTVDQGWSIVQDVMSFERVGIARYARCERLLAAAPTVLGERWDSLPTE--
Mvan_4958|M.vanbaalenii_PYR-1 GTVDAGWSIVQDVMAFERVGIARYARCERLLAAAPGVLGDRWDSLPAE--
MMAR_3981|M.marinum_M GEPGDGWRVMREALAFERVGIARYARCESLLDRMRTELGDDWARLPES--
MUL_3842|M.ulcerans_Agy99 GEPGDGWRVMREALAFERVGIARYARCESLLDRMRTELGDDWARLPES--
MAV_1629|M.avium_104 GEVGDGWRVMREALAYERVGIARYARCESLLERMRGRLGDEWEQLPES--
MLBr_00737|M.leprae_Br4923 GEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESI
* *: * . .
Mb1969c|M.bovis_AF2122/97 -----VRDGLAWCYARVQIMRYRGYRDLTLALTG-RPPGAEAAITKVIWS
Rv1934c|M.tuberculosis_H37Rv -----VRDGLAWCYARVQIMRYRGYRDLTLALTG-RPPGAEAAITKVIWS
MAB_0595c|M.abscessus_ATCC_199 -----ASERVADAWIAAQAYRLHTFGTVTRLAGG-GELGAESSITKVFWS
MSMEG_5622|M.smegmatis_MC2_155 -----LRGRWTRMLTHCRRARLMAYRVVAMQATG-RVNPGDSAAYRIAVT
TH_3217|M.thermoresistible__bu -----LHGRWARMLTHCRRARLLAYRVVALQAGG-QVRPGDAAAYRIAVT
Mflv_1792|M.gilvum_PYR-GCK -----LRGRWIRMLTHCRRARLLAYRVVALQSSG-RIAPGDAAAYRIAVT
Mvan_4958|M.vanbaalenii_PYR-1 -----LRGRWIGMLTHCRRARLLAYRVVALQSSG-RITPGDASAYRIAVT
MMAR_3981|M.marinum_M -----IRVRWVRALADLRVARLLAYRAVALRDD--PTAGAAASAARIVTT
MUL_3842|M.ulcerans_Agy99 -----SRVRWVRALADLRVARLLAYRAVALRDD--PTSGAAASAARIVTT
MAV_1629|M.avium_104 -----IRARWVRALVDLRVARLLAYRAVSLQDD--PASGAAASAARIATT
MLBr_00737|M.leprae_Br4923 STFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFAS
. * : : :: : :
Mb1969c|M.bovis_AF2122/97 EYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLY
Rv1934c|M.tuberculosis_H37Rv EYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLY
MAB_0595c|M.abscessus_ATCC_199 ELDVALHETAIDLRGAEG--------------------ELTNAWTDGYLF
MSMEG_5622|M.smegmatis_MC2_155 RLDQESAEVLMEIAAALPRGG------------DQRTEYFRAEVEDHWRY
TH_3217|M.thermoresistible__bu RLDQDSAEVLMELVAALPPGDS---------ADRQAAEYFRAEVEDHWRY
Mflv_1792|M.gilvum_PYR-GCK KLDQDSAEVLMDIAAEVRHDD-------------ERAAWFLGEVDDHWRY
Mvan_4958|M.vanbaalenii_PYR-1 KLDQDSAEVLMDIAAEVRRDD-------------HRAQWFLGEVEDHWRY
MMAR_3981|M.marinum_M TCDQQVAELLLDVLGPAALDS-------------GTTAPLHGAIEDHWRY
MUL_3842|M.ulcerans_Agy99 TCDQQVAELLLDVLGPAALDS-------------GATAPLHGAIEDHWRY
MAV_1629|M.avium_104 TCDQQVAELLFDVLGPTALDA-------------GSGAPLHGAIEDHWRY
MLBr_00737|M.leprae_Br4923 DIAMEVTTDAVQLFGGAGYTS-------------------DFPVERFMRD
.:: .
Mb1969c|M.bovis_AF2122/97 ARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC----
Rv1934c|M.tuberculosis_H37Rv ARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC----
MAB_0595c|M.abscessus_ATCC_199 SLGGPIYAGTNEIQRNIIAERILGLPRESSASARTGGAK
MSMEG_5622|M.smegmatis_MC2_155 SQASTVSSGSIEMQRILLSRTMFAG--AAR---------
TH_3217|M.thermoresistible__bu SQASTVSSGSIEMQRILLSRAMLATGKAPR---------
Mflv_1792|M.gilvum_PYR-GCK SQASTVSSGSIEMQRILLSRAMLTADARSKSASVGAPR-
Mvan_4958|M.vanbaalenii_PYR-1 SQASTVSSGSIEMQRILLSRAMLSAGAAK----------
MMAR_3981|M.marinum_M AQAATVASGTIEVQRMLVARDVLGEHR------------
MUL_3842|M.ulcerans_Agy99 AQAATVASGTIEVQRMLVARDVLGEHR------------
MAV_1629|M.avium_104 AQAATVASGTIEVQKMLVARDVLGGHR------------
MLBr_00737|M.leprae_Br4923 AKITQIYEGTNQIQRVVMSRALLR---------------
: : *: ::*: ::.. ::