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TTTAGDHRYLQVARTLRKEIVDGVYPVGSQLPTEHELCERFAVSRYTIREALRRLREDNLVASRPRAGTL VVPRPTTNAYAQDVVAIDDLLAFAQGARFAIETNAMVTIDDELADLTGLPVGTEWLAVSGYRRIDDETAP FCRTEYFINRSFAAVGRHLQRHTGPIFPLIEDLFGVSVVEVHQEISAVVLGSELAERLQISPGTAALRMK RSYTTSDGEVAQVTVNTHPSSRFRHAMTMRRVRDAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1785 | - | - | 100% (247) | regulatory protein GntR, HTH |
| M. gilvum PYR-GCK | Mflv_0447 | - | 9e-15 | 26.78% (239) | regulatory protein GntR, HTH |
| M. gilvum PYR-GCK | Mflv_4275 | - | 2e-08 | 33.33% (129) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 3e-11 | 24.26% (235) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0792c | - | 3e-11 | 24.26% (235) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2239 | - | 3e-11 | 30.00% (210) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0304 | - | 3e-95 | 69.71% (241) | GntR family transcriptional regulator |
| M. avium 104 | MAV_5211 | - | 1e-104 | 76.76% (241) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_5630 | - | 1e-110 | 78.28% (244) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_0099 | - | 1e-105 | 75.41% (244) | transcriptional regulator, GntR family protein |
| M. ulcerans Agy99 | MUL_4818 | - | 2e-95 | 69.71% (241) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4965 | - | 1e-118 | 84.49% (245) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1785|M.gilvum_PYR-GCK -----MTTTAGDHRY--------LQVARTLRKEIVDGVYPVGSQLPTEHE
Mvan_4965|M.vanbaalenii_PYR-1 -----MTATAGDHRY--------LQVARALRKEIVDGIYPVGSQLPTEHE
MSMEG_5630|M.smegmatis_MC2_155 -----MTVSPAEHRY--------LQVARTLRKEIVDGVYPVGSHLPTEHE
TH_0099|M.thermoresistible__bu -----MTVSPADHRY--------LQVARILRKEIVDGVYPVGSQLPTEHE
MAV_5211|M.avium_104 ----MPQTISGDHRY--------LQIARALRKEIVDGVYPVGSQLPTEHQ
MMAR_0304|M.marinum_M ----MSEPKILDHRY--------LQVARTLRKEIVDGIYPVGSQLPTEHE
MUL_4818|M.ulcerans_Agy99 ----MSEPKILDHRY--------LQVARTLRKEIVDGIYPVGSQLPTEHE
Mb0816c|M.bovis_AF2122/97 MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERE
Rv0792c|M.tuberculosis_H37Rv MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERE
MAB_2239|M.abscessus_ATCC_1997 ----MAAAEPTPLRRPR--ADQARLVADVLRHQIHAGGYAEGG-LPSEHA
* :* *: :* . *. **:*:
Mflv_1785|M.gilvum_PYR-GCK LCERFAVSRYTIREALRRLREDNLVASRPRAGTLVVPRPTTNAYAQDVVA
Mvan_4965|M.vanbaalenii_PYR-1 LCERFAVSRYTIREALRRLRDDNLVESRPRAGTLVVPRPSTNSYAQDVVS
MSMEG_5630|M.smegmatis_MC2_155 LCERFEVSRYTIREALRRLRDDNLVESRPRAGTTVVPRPTTNSYAQDVMS
TH_0099|M.thermoresistible__bu LSERFSVSRYTIREALRRLREDNLISSRPRAGTMVVPRPSSHAYAQDVMS
MAV_5211|M.avium_104 LCERFAVSRYTIREALRRLREDNLVASRPRAGTRVVPRPASSSYAQDAMS
MMAR_0304|M.marinum_M LCDRFAVSRYTIREALRRLREDNLVSSRPRTGTLVVPRPSSDSYVQHVMS
MUL_4818|M.ulcerans_Agy99 LCDRFAVSRYTIREALRRLREDNLVSSRPRTGTLVVPRPSSDSYVQHVMS
Mb0816c|M.bovis_AF2122/97 LIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPVEQELSCGVRTI
Rv0792c|M.tuberculosis_H37Rv LIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPVEQELSCGVRTI
MAB_2239|M.abscessus_ATCC_1997 LAAEFFVSRNTVREALTTLKDEGLIERGPRTGTHVALRKYEHGLDALLGL
* . :** *:* *: *: :. : ** *.
Mflv_1785|M.gilvum_PYR-GCK IDDLLAFAQGARFAIETNAMVTIDDELADLTGLPVGTEWLAVSGYRRIDD
Mvan_4965|M.vanbaalenii_PYR-1 IDDLLAFAQGAQFSIETNGMVTVDDALAERTGLAPGSEWFAVSGYRRADD
MSMEG_5630|M.smegmatis_MC2_155 INDLLAFATGAQFTIDSNAMVTIDDELAERTGLPVDEEWLAVRGYRQAEG
TH_0099|M.thermoresistible__bu INDLLAFATGAKFAIESVAMVTIDDELADRTGLTVDEQWLAVLGYRQADG
MAV_5211|M.avium_104 IDDLLAFAAGAQLTIESNAMVTIDDELAARTGLEPGTQWLSVRGYRQADG
MMAR_0304|M.marinum_M INDLLAFATGTRFVIESIAMATIDDEVSAQTGLASGEQWLSVCGFRRAEN
MUL_4818|M.ulcerans_Agy99 INDLLAFATGTRFVIESIAMATIDDEVSAQTGLASGEQWLSVCGFRRAEN
Mb0816c|M.bovis_AF2122/97 TEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIRRRIRTGD
Rv0792c|M.tuberculosis_H37Rv TEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIRRRIRTGD
MAB_2239|M.abscessus_ATCC_1997 KETFKGYG-EVRNEVRVIQEVNAPPAVAHRLRLDPGARVIFIERLRYLGD
: : . . : : :: * . : : .
Mflv_1785|M.gilvum_PYR-GCK ET---APFCRTEYFINRSFAAVGRHLQR--HTGPIFPLIEDLFGVSVVEV
Mvan_4965|M.vanbaalenii_PYR-1 DT---APICRTEYFINRSFAAVGRLLQR--HTGPIFPLIEDLFGVSIVEV
MSMEG_5630|M.smegmatis_MC2_155 NK---PPVCRTEYYINRSFAAVGRLLQR--HTGPIFPLIEDLFGVSVVEV
TH_0099|M.thermoresistible__bu SD---TPVCRTEYYINRAFAAVGRLLPS--HTGPIFPLIEDMFGVSIIEV
MAV_5211|M.avium_104 AP---VPICRTEYYINRSFAAVGRLLQR--HAGPIFPLIEDLFGVSVAQL
MMAR_0304|M.marinum_M AEPAEPALCRTQYYINRAFAAVGRLLHR--HDGPIFPLIEDLFGLGIVEV
MUL_4818|M.ulcerans_Agy99 AEPAEPALCRTQYYINRAFAAVGRLLHR--HDGPIFPLIEDLFGLGIVEV
Mb0816c|M.bovis_AF2122/97 QP----LALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRIAQA
Rv0792c|M.tuberculosis_H37Rv QP----LALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRIAQA
MAB_2239|M.abscessus_ATCC_1997 LP----LSLDKTYLTPDVGEAV---IEHQLETNDVFALIERVTGRRLGSA
. * ** : . :.: * * : .
Mflv_1785|M.gilvum_PYR-GCK HQEISAVVLGSELAERLQISPGTAALRMKRSYTTSDGEVAQVTVNTHPSS
Mvan_4965|M.vanbaalenii_PYR-1 HQEISAVVLDADLAAHLQAEVGAAALQMQRTYTTSDGEIAQVTVNTHPSS
MSMEG_5630|M.smegmatis_MC2_155 HQQITAVLVDTDLAELLKVSPGTAALQMQRTYTTSDGEIAQVTVNTHPSG
TH_0099|M.thermoresistible__bu HQQISAVLLGPGLADRLRDEAGSPALEMQRTYKTSDGDVAQVTVNTHPAS
MAV_5211|M.avium_104 HQEIAAVLLSPELADGLGAEAGTAALQMRRTYTTSDGEVAQVTINTHLSP
MMAR_0304|M.marinum_M QQEIAAVSISPALAHGLQVEPGSAALQIRRAYVTSDEQVAQVTLNTHPAS
MUL_4818|M.ulcerans_Agy99 QQEIAAVSISPALAHGLQVEPGSAALQIRRAYVTSDEQVAQVTLNTHPAS
Mb0816c|M.bovis_AF2122/97 THEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHHRPE
Rv0792c|M.tuberculosis_H37Rv THEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHHRPE
MAB_2239|M.abscessus_ATCC_1997 NLALEAVAADSHSAATLQVPDSAPLLLLERLTHLDDGTPVDLEYIRMRGD
: *. .. * * .:. * : * .* ::
Mflv_1785|M.gilvum_PYR-GCK RFRHAMTMRRVRDAP-----------
Mvan_4965|M.vanbaalenii_PYR-1 RFRHSMTMRRVRDTA-----------
MSMEG_5630|M.smegmatis_MC2_155 RYRHSMTMRRVKG-------------
TH_0099|M.thermoresistible__bu RFRHSMTMRRVKP-------------
MAV_5211|M.avium_104 NFRYAMTMRRVTGQAG----------
MMAR_0304|M.marinum_M RFRHSMTMRRLRGETGSSGVTDQ---
MUL_4818|M.ulcerans_Agy99 RFRHSMTMRRLRGETGSSGVTDQ---
Mb0816c|M.bovis_AF2122/97 RYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv RYQFSVTLPRTLPGSGAGIIEKRDFA
MAB_2239|M.abscessus_ATCC_1997 RITLRSNLLRDI--------------
. .: *