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MNAASVIGRVGGLAVAFGVGTAVLGGNAVASAKPAADGSDTRASVSQASETSGAADTSEPTTAADTDTRD SDIPADDAPDSDDDAADPDGAAEPDREDADGDIGLPAANEDAGDAESDDRPATSSRKPDTSDGDASTQVT SPASATSPTSDDDAPAETPDDAGAAAPTTSPVRQEQAITWLSSPAAVAGRTGAAPTPAVTASASVASPLL TLVENLFSPFAGYSPDGLPSGSPLSWAMAAAARREALVAGGPISVDPTLDFLDGVIYGSVGATDTNGRPL IYTLLDGPDQGGKITLNDDGTFSFLPDLSVVDSRGVENFTVMVSQTSVLMALLEQIPIIGDFVQPLVIGL QQVPVLGALLQPIIGYRVITTIGVDVDELVPVGAPVAFTTMVTSFDGTQISTNFFPASGLQFGETAPTVL NGPGLGSAGDIDPTSETTVFDLVPGLVPLRDGGYNVVTWDPRGEFASGGVLQLDNPFFEGRDVQAIISWV AGRPETELDAPGDPTMGMVGGSYGGGIQLVTAGIDDRVDAIVPVIAWNSLTRALYPTKAFKTGWATLLGL DLLEAGARINSQIYPAIILGDLLGFITETQEAILESSGPTVLVSSITAPTLLIQGTADGLFTLAQAVANA MLLDANGVPVEMIWACGGHGVCLDPLNPIQTPLLVNTTLDWLDRYVRGNELIPTGPRFEWFDQTGAYHSS DLLPTEPDFYGDPIVTDSDGGFLPIIPILGGSGPQTQSPTPLIVSPALASEASLALNLEIAAPAGTQIVG APEITLTYSGLGTATHIYGQLVDDATGLVLGNLVTPIPVTLNGRTQTVTIDLEQIAYTAVPGGTLTLQLA GFATPYLDLFQVGFIDVESVSLSLPTVAVGAGAGAAQAGVAVGSAAA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_2538 | - | - | 100% (887) | peptidase S15 |
M. gilvum PYR-GCK | Mflv_5229 | - | e-145 | 38.64% (898) | peptidase S15 |
M. gilvum PYR-GCK | Mflv_5192 | - | e-131 | 37.89% (797) | peptidase S15 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3469c | - | 5e-06 | 27.89% (190) | hypothetical protein Mb3469c |
M. tuberculosis H37Rv | Rv3439c | - | 6e-06 | 27.89% (190) | hypothetical protein Rv3439c |
M. leprae Br4923 | MLBr_01022 | rpoT | 7e-06 | 29.50% (139) | RNA polymerase sigma factor |
M. abscessus ATCC 19977 | MAB_4508 | - | 5e-05 | 28.24% (170) | putative membrane protein, MmpL |
M. marinum M | MMAR_2416 | lgt | 5e-08 | 25.77% (194) | prolipoprotein diacylglyceryl transferases Lgt |
M. avium 104 | MAV_4382 | - | 8e-07 | 29.17% (168) | hypothetical protein MAV_4382 |
M. smegmatis MC2 155 | MSMEG_4365 | - | 2e-09 | 25.45% (279) | hypothetical protein MSMEG_4365 |
M. thermoresistible (build 8) | TH_2316 | - | 2e-11 | 30.29% (208) | conserved hypothetical protein |
M. ulcerans Agy99 | MUL_3715 | rne | 9e-07 | 27.97% (143) | ribonuclease E Rne |
M. vanbaalenii PYR-1 | Mvan_4077 | - | 1e-164 | 41.77% (905) | peptidase S15 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3469c|M.bovis_AF2122/97 ----------------------------------------------MADR Rv3439c|M.tuberculosis_H37Rv ----------------------------------------------MADR MAV_4382|M.avium_104 ----------------------------------------------MADR Mflv_2538|M.gilvum_PYR-GCK ----------------------------------MNAASVIGRVGGLAVA Mvan_4077|M.vanbaalenii_PYR-1 ----------------------------------MGAAKYVGRVGGLAVA MSMEG_4365|M.smegmatis_MC2_155 ----------------------------------------MGRIGALAVA TH_2316|M.thermoresistible__bu ----------------------------------------VGRVGALAVA MAB_4508|M.abscessus_ATCC_1997 --------------------------------MFAWWGRMVYRYRFIVVA MMAR_2416|M.marinum_M -----------------------------------MTATVLAYFPSPPRG MUL_3715|M.ulcerans_Agy99 MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR MLBr_01022|M.leprae_Br4923 ----------------------------------MEQSRRVPPLQWLSAV Mb3469c|M.bovis_AF2122/97 LNVAERLAEG------------RPAAEHTQSYVR---------------- Rv3439c|M.tuberculosis_H37Rv LNVAERLAEG------------RPAAEHTQSYVR---------------- MAV_4382|M.avium_104 LDVAGRLAEG------------RAGVEHTQTYVQ---------------- Mflv_2538|M.gilvum_PYR-GCK FGVGTAVLGG-NAVASAKPAADGSDTRASVSQASETSGAADTSEPTTAAD Mvan_4077|M.vanbaalenii_PYR-1 LGVGVAILTG-QGVA----YADDTGTASSETTATENSSAEGPARQGAASD MSMEG_4365|M.smegmatis_MC2_155 LGIGAALTTG-TGVAWADDSGASGGSTSSSSSASDS------SSSSAGGS TH_2316|M.thermoresistible__bu LGVGVAVATGGTAVAWAD-SGSTASSSSSQDSSSKSNPAQTRSSAKSGIG MAB_4508|M.abscessus_ATCC_1997 AFVTVCLGSGLFGITLGDHVTQSGFFADNSESVKASVMADDALGRDRTTH MMAR_2416|M.marinum_M VWHLGPLPIRAYAFFIIIGIVMGLMIGDRRFAARGGERGVIYDIALWMVP MUL_3715|M.ulcerans_Agy99 IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE MLBr_01022|M.leprae_Br4923 ARPIARVLTLISTPTFDIADTFGYACPNPPEVSPTEGVYVVATKTSPATG Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4382|M.avium_104 -------------------------------------------------- Mflv_2538|M.gilvum_PYR-GCK TDTRDSDIPADDAPDSDDDAADPDGAAEPDREDADGDIGLPAANEDAGDA Mvan_4077|M.vanbaalenii_PYR-1 SDVGTG---------ADDEASDVGTVADDEASDVG-----TVADDEASDV MSMEG_4365|M.smegmatis_MC2_155 SGSASG-----------------GADAAKPRKPGV-----TKP------- TH_2316|M.thermoresistible__bu SGAGSGPGSRLDRPASRAPLGGSGADSSATEQTGA-----VSSGTSAWRS MAB_4508|M.abscessus_ATCC_1997 VVAVIAAPEGKTVDDPAFQKKVIDHFDQLQKDNPD-----EVYGWAGWLR MMAR_2416|M.marinum_M FGLIGG-------------------------------------------- MUL_3715|M.ulcerans_Agy99 PAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDADDE MLBr_01022|M.leprae_Br4923 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 ------------ACHLVGYQHPDLTAYPAQIHDWYGSEDGLDLHALDADC Rv3439c|M.tuberculosis_H37Rv ------------ACHLVGYQHPDLTAYPAQIHDWYGSEDGLDLHALDADC MAV_4382|M.avium_104 ------------ACHALGYQHPDLTAHPAQVREWYAGEDGLDLRALDRDC Mflv_2538|M.gilvum_PYR-GCK ESDDRPATSSRKPDTSDGDASTQVTSPASATSPTSDDDAPAETPDDAGAA Mvan_4077|M.vanbaalenii_PYR-1 GTVADDGAS--DVETAEDDEASDVEEQQSGGGTGEDSTTPAEPVDTADDT MSMEG_4365|M.smegmatis_MC2_155 -----RIQPTGKIAESLKKTAKAVEGAVADAHKRAQQSAAQQAEKRAERR TH_2316|M.thermoresistible__bu AGMPAGTSLTGRLADSVRDAVKPWRPATTRSTDPTPVETPAEANPEAQPD MAB_4508|M.abscessus_ATCC_1997 APTTTDPTVKRMVTEDRKHTFVSVSLKGDDDDTILNNYKALSNPDKDDDP MMAR_2416|M.marinum_M -------RLYHLSTDWQTYFGEGGAGLGAALRIWDGGLGIWGAVTLGTVG MUL_3715|M.ulcerans_Agy99 SGDEGDDDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEA MLBr_01022|M.leprae_Br4923 -----------QPVKRTATKTPATPAKRSTTKAANGSAPTKRATSTASRA Mb3469c|M.bovis_AF2122/97 AQLR---------------------------------------------- Rv3439c|M.tuberculosis_H37Rv AQLR---------------------------------------------- MAV_4382|M.avium_104 AELR---------------------------------------------- Mflv_2538|M.gilvum_PYR-GCK APTTSPVRQEQAITWLSSPAAVAGRTGAAPTPAVTASASVASPLLTLVEN Mvan_4077|M.vanbaalenii_PYR-1 ASLSAPVVS---TTVVSPPASAD----LALDPIADDSG------------ MSMEG_4365|M.smegmatis_MC2_155 AKLRAQIRP-GKDTDKQAPEKQ---------AGNEAKN------------ TH_2316|M.thermoresistible__bu AHAGSPGES-TAPETQPAPSSRGIRSMTAVLPDTESTN------------ MAB_4508|M.abscessus_ATCC_1997 AKNKFLMDGVDIQLAGLQPVASELTGTIGKDQQRMEVLS----------- MMAR_2416|M.marinum_M AWIGCRRRG----------------------------------------- MUL_3715|M.ulcerans_Agy99 PQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASR--------RR MLBr_01022|M.leprae_Br4923 TKSTTP-------------------------------------------- . Mb3469c|M.bovis_AF2122/97 -----------------------AAASVLMEALRMERSQVAVLAAAWTG- Rv3439c|M.tuberculosis_H37Rv -----------------------AAASVLMEALRMERSQVAVLAAAWTG- MAV_4382|M.avium_104 -----------------------AAGVVAAEALRLQRAQVAELAVAWTG- Mflv_2538|M.gilvum_PYR-GCK LFSPFAGYSPDGLPSGSPLSWAMAAAARREALVAGGPISVDPTLDFLDGV Mvan_4077|M.vanbaalenii_PYR-1 -TAPIGGSAADLLLLAGTR---RELQAQQEAALEIPPYSVGVTAGVIGGC MSMEG_4365|M.smegmatis_MC2_155 -AAQPATKTQRQLP--------AAPAVKVPDVITSVRARSDEVAREITTG TH_2316|M.thermoresistible__bu -TESTNTESTVQHDDSERRSSLRSTAASVPELSTPVRLADATAVRALAER MAB_4508|M.abscessus_ATCC_1997 LPVMAVVLFFVFGGVIAAGLPLMVGGLTIAGALGIMRLVTLFAPVHFFAQ MMAR_2416|M.marinum_M --------------------IPLPAFLDAVAPGVVMGQAIGRLGNYFNQE MUL_3715|M.ulcerans_Agy99 RRRRRRKSGAGDDGDEGPAPDDPPNTVVHERAPRSGDKSGNSDSGDDSGG MLBr_01022|M.leprae_Br4923 -----------------------PKASGASDAAKKARTSVKSVDTKAPS- Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4382|M.avium_104 -------------------------------------------------- Mflv_2538|M.gilvum_PYR-GCK IYGSVGATDTNGRPLIYTLLDGPDQGGKITLN-DDGTFSFLPDLSVVDS- Mvan_4077|M.vanbaalenii_PYR-1 VVGPTCTTADGS---TFTLIKDPDKGGKLALDPTTGAFRFLPFASEKNPD MSMEG_4365|M.smegmatis_MC2_155 VTGIRTAIENAAPRIALPDLRPTTNL-------ARPVTPVALKAAQPVQ- TH_2316|M.thermoresistible__bu LTERRSVTLESVR--AFTDVAATTALTSAASVAAATVEPVALITAAPEAT MAB_4508|M.abscessus_ATCC_1997 PVVTLIGLGIAIDYSLFIVSRFREEIAEGYDTETAVRRTVITSGRTVMFS MMAR_2416|M.marinum_M LYGRETTVPWGLEIFYRRDPSGFVDVHSLDGVSTGQVAVVVQPTFLYELI MUL_3715|M.ulcerans_Agy99 NEIKGIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMV MLBr_01022|M.leprae_Br4923 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 ------------------SGADAAVHFVQRHCETGNSVVTEVRAAAQRCE Rv3439c|M.tuberculosis_H37Rv ------------------SGADAAVHFVQRHCETGNSVVTEVRAAAQRCE MAV_4382|M.avium_104 ------------------AGGEAAVQLLQRHCDTAEALATELRAAAQRCE Mflv_2538|M.gilvum_PYR-GCK --------RGVENFTVMVSQTSVLMALLEQIPIIG-DFVQPLVIGLQQVP Mvan_4077|M.vanbaalenii_PYR-1 GSQNADGPSGQETFSVLVAQNTQFTTFLIGLPIVGSSILAPVIMTLQQIP MSMEG_4365|M.smegmatis_MC2_155 -----------------VSPPRPTITGLVRGLLTAAAGFSPRAATAPVAP TH_2316|M.thermoresistible__bu ---------------PAVDAEQPAAPRLVTGLL-AAVGLAPFTANSPLAP MAB_4508|M.abscessus_ATCC_1997 -----------ATLIAAALMPMLIVPQQFLRSLTYAGIASVLLAAILAVT MMAR_2416|M.marinum_M WN----------------LLVFAALIYLDRRFTIGHGRLFASYVALYCVG MUL_3715|M.ulcerans_Agy99 VR-----------DRVRTEPPHPGSRYTQIAVLEDGIVVEHFVTSAASAS MLBr_01022|M.leprae_Br4923 ------------------AQDHTTKASAAKDTLNDPEATLNTLDSDATAD Mb3469c|M.bovis_AF2122/97 SLRDNLWQLVDSKVATAIAIDERALA-----------------QRPAWLA Rv3439c|M.tuberculosis_H37Rv SLRDNLWQLVDSKVATAIAIDERALA-----------------QRPAWLA MAV_4382|M.avium_104 SLRDNLWYLIDAKAATAIAVDDRTRA-----------------QRPEWLA Mflv_2538|M.gilvum_PYR-GCK VLGALLQPIIGYRVITTIGVDVDEL------------------VPVGAPV Mvan_4077|M.vanbaalenii_PYR-1 VISTVLAPLIGTATRQDILVDIDFLR-----------------TPAETPV MSMEG_4365|M.smegmatis_MC2_155 APSPAAWALLAFARREFERAFTPGAA-----------------TALAAPA TH_2316|M.thermoresistible__bu TQSTPLLALLGWARRETDRAYTQQAR-----------------SLVTA-- MAB_4508|M.abscessus_ATCC_1997 VLPACLGVLGRHVDALSIKRFSRTKSREELENGFWGRTVVYVMQRPLVFA MMAR_2416|M.marinum_M RFCVELLRDDTATHIAGIRINSFTST-----------------FVFIGAV MUL_3715|M.ulcerans_Agy99 LVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWDAAGLGGADRK MLBr_01022|M.leprae_Br4923 DLDAEPDLDVEPSEDIDIDIEAADLG----------------LDDLEDDD Mb3469c|M.bovis_AF2122/97 AAEALTT------------------------------------------- Rv3439c|M.tuberculosis_H37Rv AAEALTT------------------------------------------- MAV_4382|M.avium_104 AAAAVTA------------------------------------------- Mflv_2538|M.gilvum_PYR-GCK AFTTMVTSFDGTQISTNFFPASGLQFGETAP----TVLNGPGLGSAGDID Mvan_4077|M.vanbaalenii_PYR-1 AYTTMVTSWDGTQISTNFFPAIADGNPDDGNPGYETILYGPGLAQAGATD MSMEG_4365|M.smegmatis_MC2_155 ITTSAVT----SAAVVNPLPGRLD--SVPVG-----WVTGVSNPSGNWPQ TH_2316|M.thermoresistible__bu -RPAVVS----TAAVVDPLPADLIGETERIG-----RITGPG-------I MAB_4508|M.abscessus_ATCC_1997 VPIVIVMLLLIIPLGNLKLGGFSEKYLPPTNSVRQAQENFDSLFPGFRTE MMAR_2416|M.marinum_M VYIILAPKGREDPASVRGTAAAAEEVPEPEP------------------- MUL_3715|M.ulcerans_Agy99 IEQALKPGDYIVVQVSKDPVGHKGARLTTQVSLAGRYLVYVAGASSTGIS MLBr_01022|M.leprae_Br4923 VVTDIEP------------------------------------------- Mb3469c|M.bovis_AF2122/97 ---------------------------EGADRPTAVEVVRQQIQPYVDDD Rv3439c|M.tuberculosis_H37Rv ---------------------------EGADRPTAVEVVRQQIQPYVDDD MAV_4382|M.avium_104 ---------------------------GQPDRDDAHNVIRQKVIPYVDND Mflv_2538|M.gilvum_PYR-GCK PTSETTVFDLVPGLVPLRDGGYNVVTWDPRGEFASGGVLQLDNPFFEGRD Mvan_4077|M.vanbaalenii_PYR-1 PE--------NPFVSTFRLGGYNVVTWDPRGEFASGGVLQLDSPQYEGQD MSMEG_4365|M.smegmatis_MC2_155 TNNT---------AGFDIWGTDLGIMWDGGEWNGQRFVHTAFGDTFSGPN TH_2316|M.thermoresistible__bu TDGP---------NRLNIYGTDLGIMWDMGEWRGQRAVHVVFGDTFSGPN MAB_4508|M.abscessus_ATCC_1997 TITIVTKGATDSQLNQIRADAMKVPGFVEPGGDKTQMWQRRQAVKTDGDT MMAR_2416|M.marinum_M ---------------AGEVATAAAPAGDTEGDEPTGLAETAKAAEVAEPE MUL_3715|M.ulcerans_Agy99 RKLPDTERQRLKEILREVVPSDAGVIIRTASEGVKEDDIRADVTRLQERW MLBr_01022|M.leprae_Br4923 ----------------------------GETEDGEATAATKTDEASTDDD Mb3469c|M.bovis_AF2122/97 VRN--DWLTTMRSTTAGVAAS------YDAVTDQLASAPRAHFEIPDDLG Rv3439c|M.tuberculosis_H37Rv VRN--DWLTTMRSTTAGVAAS------YDAVTDQLASAPRAHFEIPDDLG MAV_4382|M.avium_104 IRN--EWLTAMRSATDGVQTS------YAMVVDRMAAAPAARFELPGDLG Mflv_2538|M.gilvum_PYR-GCK VQAIISWVAGRPETELDAPGDPTMGMVGGSYGGGIQLVTAGIDDRVDAIV Mvan_4077|M.vanbaalenii_PYR-1 VSQLISWAAGLDGVELDGVGDPTLGMVGVSYGGGIQFVTAAGDNRVDAIA MSMEG_4365|M.smegmatis_MC2_155 MSG--WWRSNVLLISTDNVLSDGLG--LVQTGTAYQFIPASGRNLFGLFG TH_2316|M.thermoresistible__bu MSG--DWISNAIMISTSRTLYENPAGFLEQTGPAFQFIP--GGQLLSWFF MAB_4508|M.abscessus_ATCC_1997 SVKVIQNALVDRNTAGAKVKQLREIPVPKGVTMYVGGTPALEQDSIDTVF MMAR_2416|M.marinum_M TVG--SAVAGDESTADTEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEV MUL_3715|M.ulcerans_Agy99 NQIEAKAVEIKQKAAGAAVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDA MLBr_01022|M.leprae_Br4923 EEIVEPTEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIG Mb3469c|M.bovis_AF2122/97 PGRQPSPAS--------------------VPAQPSATAAITP-------- Rv3439c|M.tuberculosis_H37Rv PGRQPSPAS--------------------VPAQPSATAAITP-------- MAV_4382|M.avium_104 SGLVPVPATRPLVAAPMPPLDAAPTLPDAAPTLPAAVSEPAA-------- Mflv_2538|M.gilvum_PYR-GCK PVIAWNSLTRALYPTKAFKTGWATLLGLDLLEAGARINSQIYP-----AI Mvan_4077|M.vanbaalenii_PYR-1 PGWAWNTLPDSLYPDRSFKTAYSSLLLLGLVTTGARINPQIYG-----GI MSMEG_4365|M.smegmatis_MC2_155 GSEVTVIPTAGVQIDG---TQYVNYMSVRSWDTPGRWTTNFS-------- TH_2316|M.thermoresistible__bu PAEVTVIPTAGVHANG---TQYVNYMSVRQWGVPGSWTTNFS-------- MAB_4508|M.abscessus_ATCC_1997 DKLPFVIVVLISVTTILMFLAFGSLVLPIKAAVMSALGLGSTMGILTWIF MMAR_2416|M.marinum_M AEAVEGEVEEAEEAEPGEVEVAEAVEGEVEAAAEAEEAEEAEEA------ MUL_3715|M.ulcerans_Agy99 WDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEH---LA MLBr_01022|M.leprae_Br4923 KVALLNAEEEVELAKRIEAGLYATQLMTELSERGTKLPTAQRR------- Mb3469c|M.bovis_AF2122/97 ----AAALPPPDPVPAVTSRPVTP--SDFGSAPG-DGSATPAG-VGSAGG Rv3439c|M.tuberculosis_H37Rv ----AAALPPPDPVPAVTSRPVTP--SDFGSAPG-DGSATPAG-VGSAGG MAV_4382|M.avium_104 ----AATLPAAAPTPAAVPPAAAAPAADWGAALG-DVAGMPAGDLGGLAE Mflv_2538|M.gilvum_PYR-GCK ILGDLLGFITETQEAILESSGPTVLVSSITAPTL-LIQGTADGLFTLAQA Mvan_4077|M.vanbaalenii_PYR-1 ITGAILGVLTPGQIQLLQTSGPGQTVRGISAPTL-IIQGTVDVLFPLQQS MSMEG_4365|M.smegmatis_MC2_155 ----AISVYDPSTDTWVLAPSTIRSAGWFRSSTL-YVPGSQN---FQQAA TH_2316|M.thermoresistible__bu ----AISRYDQATDTWVTVPSSVRSAGWLRSSTP-YRAGDQN---FQQMA MAB_4508|M.abscessus_ATCC_1997 VDGHFSKWLNFTPTPLTAPVIVLIIVVIYGLSSDYEVFLMSRMIEARHQG MMAR_2416|M.marinum_M --EEAEEAEEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEVEAVDEAAEAE MUL_3715|M.ulcerans_Agy99 KAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSGGNLEQTVTKNNLE MLBr_01022|M.leprae_Br4923 ----DMMWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGN Mb3469c|M.bovis_AF2122/97 FGDAGGTG-GLGGFAGLAGLAN---------------------------- Rv3439c|M.tuberculosis_H37Rv FGDAGGTG-GLGGFAGLAGLAN---------------------------- MAV_4382|M.avium_104 SGMGSGLGSGLGGGGGLLGLAG---------------------------- Mflv_2538|M.gilvum_PYR-GCK VANAMLLDANGVPVEMIWACGGHGVCLDP--------------------- Mvan_4077|M.vanbaalenii_PYR-1 IVNEGLLALN-EDVKMLWFCGGHGSCLPG--------------------- MSMEG_4365|M.smegmatis_MC2_155 YVLQPEDQVGEDGIRYLYAFG----------------------------- TH_2316|M.thermoresistible__bu YVLQPVDQVGEDGVRYVYAFG----------------------------- MAB_4508|M.abscessus_ATCC_1997 LSTTEAVRVGTANTGRIITAAALILIVVAGGFAFSDLVMMKYLAFGLIAA MMAR_2416|M.marinum_M APEVGEIEAAEAVEGEVEVAAEAEEAEAG--------------------- MUL_3715|M.ulcerans_Agy99 AAEEIVRQLRLRDIGGIVVIDFIDMVLESN-------------------R MLBr_01022|M.leprae_Br4923 LGLIRAVEKFDYTKGYKFSTYAT--------------------------- Mb3469c|M.bovis_AF2122/97 ----------RIVDAVDSLLG-------------SVAEQLG--DPLAADN Rv3439c|M.tuberculosis_H37Rv ----------RIVDAVDSLLG-------------SVAEQLG--DPLAADN MAV_4382|M.avium_104 ----------KIVDAMGGLLG-------------SVGDGLDGSDPFGDQD Mflv_2538|M.gilvum_PYR-GCK -LN--PIQTPLLVNTTLDWLDR----YVRGNELIPTGPRFEWFDQTGAYH Mvan_4077|M.vanbaalenii_PYR-1 -QGNGEADSAWVMRETLAWMYR----YVK-DDGSQDDVVFEWTDQYGDRW MSMEG_4365|M.smegmatis_MC2_155 ------TPSGRAGSAYLSRVP---------EDAVTDLSKYEYWD--GNRW TH_2316|M.thermoresistible__bu ------TPSGRQGSVHLSRVP---------EEHITDVSKYEYWD--GNAW MAB_4508|M.abscessus_ATCC_1997 LILDATVVRMLLIPAVMKLLGDDCWWAPAWMKRIQVKLGLGEVTLPDERK MMAR_2416|M.marinum_M ------EDEPKEAEEVAEAEGS------------EAEDKTVQAIDGGQTG MUL_3715|M.ulcerans_Agy99 DLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPH MLBr_01022|M.leprae_Br4923 ---------WWIRQAITRAMAD--------------QARTIRIPVHMVEV Mb3469c|M.bovis_AF2122/97 PPG----AVDPF-AEDAADN------------------ADDGDDAHPEEA Rv3439c|M.tuberculosis_H37Rv PPG----AVDPF-AEDAADN------------------ADDGDDAHPEEA MAV_4382|M.avium_104 PLDDNAFHGDPFHADDPADA------------------KDAGDDADETAA Mflv_2538|M.gilvum_PYR-GCK SSDLLPTEPDFYGDPIVTDS----DGGFLPIIPILGGSGPQTQSPTPLIV Mvan_4077|M.vanbaalenii_PYR-1 TSEVSPTEAGFYDPPGVIPTTVWDTGKVLPIIPLIGGSGPNPEVPLPYSL MSMEG_4365|M.smegmatis_MC2_155 VTGNAAVAAPVIGDSTRSTG-------------LFGFIVDWANDPNVLGG TH_2316|M.thermoresistible__bu VS-SAAHAAPIIGESTRSAG-------------LFGFIIDWANDPNVFGG MAB_4508|M.abscessus_ATCC_1997 RPTGREQAIAAASSPVGSNARTTKLPIASERTRLPSTPTPRQHDPSAPAR MMAR_2416|M.marinum_M VDDAGEADAEPDDDSTAAEP------------------EVVVEQADIEEI MUL_3715|M.ulcerans_Agy99 CSGRGILLHADPVDSAPTTGRKADSGGRRNRRSKKNRAEEPSEKEAVAKV MLBr_01022|M.leprae_Br4923 INKLGRIQRELLQDLGREPTP-----------------EELAKEMDITPE . Mb3469c|M.bovis_AF2122/97 DEAAEPKEATEPDEADEVDDADESVP------AERAQDVAEEATLPPVAE Rv3439c|M.tuberculosis_H37Rv DEAAEPKEATEPDEADEVDDADESVP------AERAQDVAEEATLPPVAE MAV_4382|M.avium_104 DEPGAPD---RPAPAGEAEPSGEPAP------SGEAAPTGEPAQP---VE Mflv_2538|M.gilvum_PYR-GCK SPALASEASLALNLEIAAPAGTQIVGAPEITLTYSGLGTATHIYGQLVDD Mvan_4077|M.vanbaalenii_PYR-1 GDGSIASNAVTIALENPV-AEANVVGSPSVVIHYSGFGTSRHIYAQVVDR MSMEG_4365|M.smegmatis_MC2_155 YLGGLVGAKTGGNVSELSVQYNEYLG---KYVVLYGDG-NNNIQMRIADR TH_2316|M.thermoresistible__bu YLGGLFGAKTGGNVGEMSVQYNEYLG---KYVILYGNGRTNNIEMRIADS MAB_4508|M.abscessus_ATCC_1997 PTPPPPAPPTAPVNLAGNDSGDASATTRMAVPGKNVAPTDAPTTRVPGGN MMAR_2416|M.marinum_M EPQEPEAEAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVDVDATAT MUL_3715|M.ulcerans_Agy99 PTYAPGEHPMFKAMAASSSSEAEHGDGEVEESGEELTAAVDDQTAVQVAL MLBr_01022|M.leprae_Br4923 KVLEIQQYAREPISLDQTIGDEGDSQLGDFIEDSEAVVAVDAVSFTLLQD Mb3469c|M.bovis_AF2122/97 PPPPAAPPVAE--------------------------------------- Rv3439c|M.tuberculosis_H37Rv PPPPAAPPVAE--------------------------------------- MAV_4382|M.avium_104 ATPPAAPPPAA--------------------------------------- Mflv_2538|M.gilvum_PYR-GCK ATGLVLGNLVT--------------------------------------- Mvan_4077|M.vanbaalenii_PYR-1 STGLVVGNIVT--------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 PEGPWSDPIEL--------------------------------------- TH_2316|M.thermoresistible__bu PEGPWSDPIIL--------------------------------------- MAB_4508|M.abscessus_ATCC_1997 PAGPDAPTTRSSVAGTHRPDRRNADREIESWLGELRGPKQPGAAAGTEAG MMAR_2416|M.marinum_M EAEESGDESPE--------------------------------------- MUL_3715|M.ulcerans_Agy99 DLGETEESEETDG-------------------------------TDETDD MLBr_01022|M.leprae_Br4923 QLQSVLETLSERE------------------------------------- Mb3469c|M.bovis_AF2122/97 ---PPPPVAAPAPPGAPEPANGPSPEALSEGATPCEIAADELPQAGP--- Rv3439c|M.tuberculosis_H37Rv ---PPPPVAAPAPPGAPEPANGPSPEALSEGATPCEIAADELPQAGP--- MAV_4382|M.avium_104 ---PPP-GAPPADPGPAPAAAQPTPEP---GSTPCQIAADQLPQAGQ--- Mflv_2538|M.gilvum_PYR-GCK ---PIPVTLNGRTQTVTIDLEQIAYTAVPGGTLTLQLAGFATPYLDLFQV Mvan_4077|M.vanbaalenii_PYR-1 ---PVPVTLNGRDQVVTVDLNDIAYTVGPDSELELQIFTTATSYFNATQF MSMEG_4365|M.smegmatis_MC2_155 ---ASSADYPGLYAPMIHPWSGTGMLEDDNGDPDVNNLYWNMSLWGDYNV TH_2316|M.thermoresistible__bu ---ATPQQYPGLYAPMIHPWSGTGYLLDENGDPDPESLYWNMSMWGPYNV MAB_4508|M.abscessus_ATCC_1997 DATTAIPVSKPQSTPRPAQPNRASGTPGEDATTAMPIAKPEVQRQGPPRA MMAR_2416|M.marinum_M ----PAADSEEPEADESAPEDSAEDTSSGESDTQSELEQSQTIEQGSDQT MUL_3715|M.ulcerans_Agy99 FDDDSDDSDDSDEDDDTDETNDTDVDADEDEDTDDDSDEDEDTEDDDELD MLBr_01022|M.leprae_Br4923 --AGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSR Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4382|M.avium_104 -------------------------------------------------- Mflv_2538|M.gilvum_PYR-GCK GFIDVESVSLSLPTVAVGAGAGAAQAGVAVGSAAA--------------- Mvan_4077|M.vanbaalenii_PYR-1 GFINVESVEVTMPTTTKGTNQGPNPSLPEMPEVLVAV------------- MSMEG_4365|M.smegmatis_MC2_155 VLMQTDLSGLKTVAV----------------------------------- TH_2316|M.thermoresistible__bu YLMQTDLSSLVEV------------------------------------- MAB_4508|M.abscessus_ATCC_1997 QRPQPEQQQPAKPSTDATEALPAPGQNRTPQQQEVDEATRRSRGGSVSAQ MMAR_2416|M.marinum_M SAGDGEGPPPSAAVDGDTGPTRQGWRGRLRNRMRRSGR------------ MUL_3715|M.ulcerans_Agy99 DDLDDELDDDDSDSDDEDSESELTEPAAGRPAALEVTTIAERPRRRRAAG MLBr_01022|M.leprae_Br4923 SQVLRDYLD----------------------------------------- Mb3469c|M.bovis_AF2122/97 ---------- Rv3439c|M.tuberculosis_H37Rv ---------- MAV_4382|M.avium_104 ---------- Mflv_2538|M.gilvum_PYR-GCK ---------- Mvan_4077|M.vanbaalenii_PYR-1 ---------- MSMEG_4365|M.smegmatis_MC2_155 ---------- TH_2316|M.thermoresistible__bu ---------- MAB_4508|M.abscessus_ATCC_1997 DLLRREGRRI MMAR_2416|M.marinum_M ---------- MUL_3715|M.ulcerans_Agy99 RPAGPPIHLG MLBr_01022|M.leprae_Br4923 ----------