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MGVSRCIGRVGALAVALGVGTAVTFPHTALADEGAGSNGSVSSSSRESTSGATGTSDRESSSSPSKPAAT RPSDSDDTETSGPDGDEPNADGSEPTEEDTEPSSTPATSPEPPADPVVEDTTDEALADPDPAESLAPSTL HPESGSTPEPVHSITATTVADLPTSAPPEEPASQPPRTDVPAAYPRTSPAIQAPASSVGALSTPVSQPVS LVGALVSTVLAPFSGGAPAAPSQPPLLWVVLAWVRRELQRTFANSTPTTTPQSVTLTLDSATSVSAPIEF DADDVDDDPLVYTVPGRGAVGGPTHGTVTVDQTTGTFTYNPDDAYALIGGTDTFTYTVSDAGARRTFFGI PLSRSATTATGIVTVTLNPVHVAPVTNGDTATTVEDRPVTIAVLGNDTDANGDALTVSGVTQGTSGTVTF TASGVTYTPNADFTGTDTFTYTATDGRSAGTATVTVTVTPVDDAPVAVGDSVTVAEDSGTTVIDVLANDI DVDGGPKVVTGVTPPAHGTVTAIGPSLSYTPAADFDGTDAFTYTLNDGSTATVTVIVTPVDDKPVAVGDT VTVAEDSSPTVIDVLANDTDIDAGPKTITGVSQPAKGNVVVTGTTVIYTPTADFTGTDTFTYTLNGGATA TVTVTVTPVDDAPVTVGDTATVAEDSGPTIIDVLANDTDIDAGPIAITAVTQPVDGTVTFTASEVTYTPG ADFHGTDTFTYTLNGGATATVTVTVTPVDDAPVTVGDAVTVAEDSGPTIIDVLVNDTDIDAGPIAITAVT QPVDGTVTFTASEVTYTPGADFHGTDTFTYTLNGGSVAVVTVIVDRVDDTPIAFGDSVTVAEDSGPTTID VLANDTDIDNGPIAITAVTQPTNGTIDFTVSRVTYTPGANFHGTDTFTYTLNGGATATVTVTVNAAPVIG QVTTTPGVGNTWEVSVSADDSENDTLTTTVTSADPTVPLTVTKQTDGTFQVVADPTWASAHPAAQIAVTV TVTDTYGSSATITTAIGTANNVISLGWDATGVGNVPALPAGVSYTQVAGGAFHTVFLRSDGSVVGAGQNN YGQLDIPPLPTGITYTQVAAGAWHTVLLRSDGTVVAVGDNFKGQIDIPEPGLGVSYTGVAAGELGTILLR SDGTAVAVGDGQYGQLEIPTLPPGVRYTQAAIGSVRSALLRSDGTVVTVGMNDAVPTLPAGVRYISVASG AGHAVLLRSDGVAVAFGANDWGQTDIPALPAGVVYVNIAASRYHSVLLRSDGTSVAAGQNTSEQLDIPVL PVGVTYTGGAAGGYSTWLISSTTATPFNTPPVAVDDAMTVAEGNTATISVTANDTDADGTIDTATVVITR QSTAGSVAVNAAGTVTYVSNGTEVTADSFAYRIDDALGATSNEATVFITITPVDDAPVAVNDAVTVAEGG TITIAVIGNDTDADGTIDTTTVVIVTQPTAGTATVNGDGTVTYVSDGSEVTSDSFTYTVKDTAGLTSNVA TVSITVNPVNDAPVAVNDAYTVAENGLLVIDAPGLLGNDLDSEHPFIYITTITNPRHGTFDGILSDGSFT YRPHAGYFGTDSFTYQINDVTGLTSNTATVTITITPVDDAPVAVNDAVTVAEDSGTTVIDVLANDTDIDA GPKTITSITQPNSGTTTITATGVAYTPNENFHGTDTFTYTLNGGTSAEVTVTVTPVNDAPVAPDKVVTIS EDTWSVAIHLTDGATDVDGDPLRRGYVTYPAIGSTFVDSDNLGIQRLLRYYPPANYTGQITIPYTVWDGQ VFSNWATITINVTPVNDVPVAVNDSAAVDAGGTTTITLTANDTDVDTDNGVDPATIVIGTQPSAGTVTVN SDGTVTYTSTGTTTTTDIFTYTVEDTTGLVSNPATVTVNVTATATPPVAVNDTVTVDEGGTTTLAVIAND TDADGDIDTATVVIVRQPTAGTATVNSDGTVSYASDGSEITTDSFEYTVRDVAGAVSNAATVIITVTPVD DAPVAVNDTVTITEDTLATFIDVLANDTDIDGGPKTITSITSPAGGHALVIGNRVRYFSAPNFHGTETFT YTLNGGATATVTVIVTPISEAPVIHRVTSTPGVGNTWVLSVDASDDDGGALTTTVTSANATVPLTITRLP GGAIQVDIDPTWARAHPGAQLPVTVTVTDAENISATKQLTIGTVSNAVFFGHNIYGQRNIPALPEGVTYT QVATASLSHTVLLRSDGTAVAVGDNFRGQLNIPPLPTGMTYTQVANGTEHTVLLRSDGTAIAVGNNSDGQ LNIPRLPAGVTYTRIAAGNYGTVLLRSDGTAVGAGYNTYGQLNIPQPPPGVTYTQAAVGLTHTVLLRSDG TAVALGDNAFGQTVIPALPTGLKYTQVAAGDLHSVLLRSDGSVVAFGNNQWGQSTVPALPAGLRYTQVAA GRYNSMLLRSDGTAIGFGQNASSQLNIPVLPAGLVYTQAAASNHTVLLFSTSSSFNSLPLATNDAATVAE GGTITFSVTANDTDTDGTLNTATVVITRQPTSGSVTVNAGGTVTYVSNGAEVSADSFAYRVNDNKGATSN EATVSITITPVNDAPVAVDDAYTVAKNGVLVISAPGLLANDSDPEGNSFTIVAATGTQHGTVDPLYSNGS FTYRPAAGYSGTDTFTYTISDGTSTAQATVTIAVSAVDNQAPVAVADSYTVAEDGVLNVTGPGVLANDTD ADGDPLSVVAAGPTSHGTFTLRSDGSFTYTPVANFHGTDSFTYQVSDGSGPSAPATVTITVTPVNDAPVV QNDTIPFPKDGFIGFSLANRSSDVDGDTLTATLISGTTHGTLFFDGTNRAFSYRPNTGFTGQDSFTYKVN DGTVDSAIATVTLNVS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0506 | - | - | 100% (2816) | putative outer membrane adhesin like protein |
M. gilvum PYR-GCK | Mflv_4855 | - | e-120 | 26.29% (2111) | YVTN beta-propeller repeat-containing protein |
M. gilvum PYR-GCK | Mflv_3001 | - | 7e-44 | 24.04% (2055) | chitinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0912 | - | 7e-15 | 32.40% (179) | hypothetical protein Mb0912 |
M. tuberculosis H37Rv | Rv0888 | - | 7e-15 | 32.40% (179) | hypothetical protein Rv0888 |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2960 | - | 7e-09 | 26.43% (227) | hypothetical protein MAB_2960 |
M. marinum M | MMAR_2591 | - | 1e-22 | 21.29% (1968) | PPE family protein, PPE8 |
M. avium 104 | MAV_3172 | - | 1e-06 | 25.90% (139) | prolipoprotein diacylglyceryl transferase |
M. smegmatis MC2 155 | MSMEG_4365 | - | 2e-14 | 26.88% (372) | hypothetical protein MSMEG_4365 |
M. thermoresistible (build 8) | TH_2316 | - | 7e-15 | 26.38% (398) | conserved hypothetical protein |
M. ulcerans Agy99 | MUL_3169 | - | 2e-11 | 22.40% (1384) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_3594 | - | 4e-42 | 25.76% (1145) | YVTN beta-propeller repeat-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0912|M.bovis_AF2122/97 MDYAKRIGQVGALAVVLGVG---AAVTTHAIGSAAPTDPSSSSTDSPVDA Rv0888|M.tuberculosis_H37Rv MDYAKRIGQVGALAVVLGVG---AAVTTHAIGSAAPTDPSSSSTDSPVDA MSMEG_4365|M.smegmatis_MC2_155 ------MGRIGALAVALGIG---AALTTG-TGVAWADDSGASGGSTSSSS TH_2316|M.thermoresistible__bu ------VGRVGALAVALGVG---VAVATGGTAVAWAD-SGSTASSSSSQD MMAR_2591|M.marinum_M MNFSVLPPEINSLRLFSGAGSTSMLEAAAAWGSLADELQVAASSFSSVTA MUL_3169|M.ulcerans_Agy99 MNFSVLPPEINSLRLFSDAGSTSMLEAAAAWGSLADELQVAASSFSSVTA Mflv_0506|M.gilvum_PYR-GCK MGVSRCIGRVGALAVALGVG-TAVTFPHTALADEGAGSNGSVSSSSREST Mvan_3594|M.vanbaalenii_PYR-1 MGHSTYIGRIGALAFALGVGVGLGATPAVAFADETGTSASSPAGENTTSG MAV_3172|M.avium_104 ------MTKLLAYFPSPPQGVWHLGPVPIRAYALFIIAGIVAALLIGDRR MAB_2960|M.abscessus_ATCC_1997 ------MTTVPSPAEDTAMRMWEFPEENPEPPARWGKYVPGEPQLRAAAF : : Mb0912|M.bovis_AF2122/97 CSPLG-------------------------------------GSASSLAA Rv0888|M.tuberculosis_H37Rv CSPLG-------------------------------------GSASSLAA MSMEG_4365|M.smegmatis_MC2_155 SASDS------SSSSAGGSSGSASG-----------------GADAAKPR TH_2316|M.thermoresistible__bu SSSKSNPAQTRSSAKSGIGSGAGSGPGSRLDRPASRAPLGGSGADSSATE MMAR_2591|M.marinum_M GLASGAWQGPASAAMSAVAAPYASWLSAAAAQAAGTAGRASAAAAVFEAA MUL_3169|M.ulcerans_Agy99 GLASGAWQGPASAAMSAVAAPYASWLSAAAAQAAGTAGRASAAAAVFEAA Mflv_0506|M.gilvum_PYR-GCK SGATGTSDRESSSSPSKPAATRPSDSDDTETSGPDGDEPNADGSEPTEED Mvan_3594|M.vanbaalenii_PYR-1 PGTAADAPTETDVDEQDEAAVDEPE----------------QPAEENDAD MAV_3172|M.avium_104 WEARG-------------------------------------GERGVIYD MAB_2960|M.abscessus_ATCC_1997 GTLVG-------------------------------------LLVAVLMG . Mb0912|M.bovis_AF2122/97 IPGASVPQVG----------------------VRQVDPGSIPDDLLNALI Rv0888|M.tuberculosis_H37Rv IPGASVPQVG----------------------VRQVDPGSIPDDLLNALI MSMEG_4365|M.smegmatis_MC2_155 KPGVTKP--------------------------RIQPTGKIAESLKKTAK TH_2316|M.thermoresistible__bu QTGAVSSGTSAWRS--------------AGMPAGTSLTGRLADSVRDAVK MMAR_2591|M.marinum_M QAAIVHPAMVAANRNE--LVALVISNLFGQNAPAIAATEAVYEQLWAQDV MUL_3169|M.ulcerans_Agy99 QAAIVHPAMVAANRNE--LVALVISNLFGQNAPAIAATEAVYEQLWAQDV Mflv_0506|M.gilvum_PYR-GCK TEPSSTPATSPEPPADPVVEDTTDEALADPDPAESLAPSTLHPESGSTPE Mvan_3594|M.vanbaalenii_PYR-1 AVETVRDRQDRIVDTD---------------PEPVAASDDAPETEPEPEP MAV_3172|M.avium_104 IALWTVP------------------------------FGLVGGRLYHLAT MAB_2960|M.abscessus_ATCC_1997 AAYAAQPGASLWALN-----------------KTIFPTHSQDIAVRAVVS Mb0912|M.bovis_AF2122/97 DFLAAVRNGLVPIIENRTPVANPQQVSVPEGG------------------ Rv0888|M.tuberculosis_H37Rv DFLAAVRNGLVPIIENRTPVANPQQVSVPEGG------------------ MSMEG_4365|M.smegmatis_MC2_155 AVEGAVADAHKRAQQSAAQQAEKRAERRAKLRAQIRPGKDTDKQAPEKQ- TH_2316|M.thermoresistible__bu PWRPATTRSTDPTPVETPAEANPEAQPDAHAGSPGESTAPETQPAPSSRG MMAR_2591|M.marinum_M AVMAGYHAGVSAIAQQLAPWQQALALPAADADFSLSIFGLQLVKTGTANA MUL_3169|M.ulcerans_Agy99 AVMAGYHAGVSAIAQQLAPWQQALALPAADADFSLSIFGLQLVKTGTANA Mflv_0506|M.gilvum_PYR-GCK PVHSITATTVADLPTSAPPEEPASQPPRTDVPAAYPRTSPAIQAPASSVG Mvan_3594|M.vanbaalenii_PYR-1 AVDEAVTAPEDAPTGDPAPDVAPPTGPEADTVAEIPSPGAEPVEAPASTS MAV_3172|M.avium_104 DWRTYWGPGGAGFGAAVRIWDGGLGIWGAVALG----------------- MAB_2960|M.abscessus_ATCC_1997 DLKNAQDILGNNKQPSPDQLTQARSSLNEAKQGLEFVSDSDERTSLQNLY Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 ----------------------AGNEAKNAAQPATKTQRQLP-------- TH_2316|M.thermoresistible__bu IRSM--------------TAVLPDTESTNTESTNTESTVQHDDSERRSSL MMAR_2591|M.marinum_M TTTF--------------GGLAIASGANSSADAGVADIAFAFGSGSSASA MUL_3169|M.ulcerans_Agy99 TTTF--------------GGLAIASGANSSADAGVADIAFAFGSGSSASA Mflv_0506|M.gilvum_PYR-GCK ALSTPVSQPVSLVGALVSTVLAPFSGGAPAAPSQPPLLWVVLAWVRRELQ Mvan_3594|M.vanbaalenii_PYR-1 VTLS----------------TILSSLLAPPRTPDAPSESPLWLVVAAALR MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 LQLN---------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 AAPAVKVPDVITSVRARSDEVAREITTGVTGIRTAIENAAPRIALPDLRP TH_2316|M.thermoresistible__bu RSTAASVPELSTPVRLADATAVRALAERLTERRSVTLESVR--AFTDVAA MMAR_2591|M.marinum_M TGGVLNIAGVGGANSSASATGGINIGTGALAFGDGNTVNASSIGVANIGT MUL_3169|M.ulcerans_Agy99 TGGVLNIAGVGGANSSASATGGINIGTGALAVGDGNTVNASSIGVANIGT Mflv_0506|M.gilvum_PYR-GCK RTFANSTPTTTPQSVTLTLDSATSVSAPIEFDADDVDDDPLVYTVPGRGA Mvan_3594|M.vanbaalenii_PYR-1 RQLDSPTTSGEAGLSSTLLTPEEAEAIRRLGDITTGPNPTDVVSTDTRAY MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------QQLRQYTPEQAQQ Mb0912|M.bovis_AF2122/97 -------------TVGPVRFDACDPDG----------------------- Rv0888|M.tuberculosis_H37Rv -------------TVGPVRFDACDPDG----------------------- MSMEG_4365|M.smegmatis_MC2_155 TTNL-------ARPVTPVALKAAQPVQ----------------------- TH_2316|M.thermoresistible__bu TTALTSAASVAAATVEPVALITAAPEATPA-------------------- MMAR_2591|M.marinum_M VAAAFGNNNSVTAIANGVENNATVAAAFGN-------------------- MUL_3169|M.ulcerans_Agy99 VAAAFGNN-SVTAIANGVENNATVAAAFGN-------------------- Mflv_0506|M.gilvum_PYR-GCK VGGPTHGTVTVDQTTGTFTYNPDDAYALIGGTDTFTYTVSDAGARRTFFG Mvan_3594|M.vanbaalenii_PYR-1 VAHPGSKSITVIDTVNGTVLQTISLWSTPT-------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 LPALPAPPGVNTDTNLAANIGPAAPASSPP-------------------- Mb0912|M.bovis_AF2122/97 ------------------NRMTFAVRERGAPGGPQHG-----IVTVDQRT Rv0888|M.tuberculosis_H37Rv ------------------NRMTFAVRERGAPGGPQHG-----IVTVDQRT MSMEG_4365|M.smegmatis_MC2_155 -VSPPRPTITGLVRGLLTAAAGFSPRAATAPVAPAPSPAAWALLAFARRE TH_2316|M.thermoresistible__bu -VDAEQPAAPRLVTGLL-AAVGLAPFTANSPLAPTQSTPLLALLGWARRE MMAR_2591|M.marinum_M -NNTDVSAIVNGVENTGVVSAVFGSDNSGVSAN-AFGVENNAIVATAAGS MUL_3169|M.ulcerans_Agy99 -NNTDVSAIVNGVENTGVVSAVFGSDNSGVSAN-AFGVENNAIVATAAGS Mflv_0506|M.gilvum_PYR-GCK IPLSRSATTATGIVTVTLNPVHVAPVTNGDTATTVEDRPVTIAVLGNDTD Mvan_3594|M.vanbaalenii_PYR-1 KLALSRGGGRLYISNALAGTVSVISTATNSVVKTIRVGDTPTGIAVSPGG MAV_3172|M.avium_104 -----------------AVGAWIGCRRHGIPLPAFADALAPGIILAQAIG MAB_2960|M.abscessus_ATCC_1997 ---PSWGYATAASAPAPAAESYLVPPPAGIPVDPVPDWPAPVAPPLTPNL . Mb0912|M.bovis_AF2122/97 AS-----------------------FIYTADPGFVGTDTFSVNVSDDTS- Rv0888|M.tuberculosis_H37Rv AS-----------------------FIYTADPGFVGTDTFSVNVSDDTS- MSMEG_4365|M.smegmatis_MC2_155 FE-----------------------RAFTPGAATALAAPAITTSAVTSA- TH_2316|M.thermoresistible__bu TD-----------------------RAYTQQARSLVTA---RPAVVSTA- MMAR_2591|M.marinum_M GN-----------------------SNVMANAGGVGANEILVAAALGNNN MUL_3169|M.ulcerans_Agy99 GN-----------------------SNVMANAGGVGANEILVAAALGNNN Mflv_0506|M.gilvum_PYR-GCK ANGDALTVSGVTQGTSGTVTFTASGVTYTPNADFTGTDTFTYTATDGRS- Mvan_3594|M.vanbaalenii_PYR-1 TR----------------------VYVVNSDDGTVSKISTLTNKVVGTVY MAV_3172|M.avium_104 RLG-----------------------NYFNQELYGRETTLPWGLEIFYRR MAB_2960|M.abscessus_ATCC_1997 LDLGG------------------YDPSWSLLYGYNVLDWFNWGLSGFNRY Mb0912|M.bovis_AF2122/97 ---LHVHGLAGYLG------------------------------------ Rv0888|M.tuberculosis_H37Rv ---LHVHGLAGYLG------------------------------------ MSMEG_4365|M.smegmatis_MC2_155 ---AVVNPLPGRLD--SVPVGWVTGVSNPSGNWPQTNNTAGFDIWGTDLG TH_2316|M.thermoresistible__bu ---AVVDPLPADLIGETERIGRITGPG-------ITDGPNRLNIYGTDLG MMAR_2591|M.marinum_M SAIANATGVGGTLGTGAISLIGNNNTLYADATGAGHIGTVASALFGDNNG MUL_3169|M.ulcerans_Agy99 SAIANATGVGGTLGTGAISLIGNNNTLYADATGAGHIGTVASALFGDNNG Mflv_0506|M.gilvum_PYR-GCK ---AGTATVTVTVTPVDDAPVAVGDSVTVAEDSGTTVIDVLANDIDVDGG Mvan_3594|M.vanbaalenii_PYR-1 G---VGKGVSTITVSPDGATIYALNGTTGEISHFSAASLFAGKITGVTPG MAV_3172|M.avium_104 DPSGYIDP------------------------------------------ MAB_2960|M.abscessus_ATCC_1997 GYDFMGFDRWGYDRWGYDRWGYDRWGYNWDGYNWSGYNRDGRDRDGRNEW Mb0912|M.bovis_AF2122/97 ------PFHGH--DDVATVT--VFVGNTPTDTISGDFSMLTYN------- Rv0888|M.tuberculosis_H37Rv ------PFHGH--DDVATVT--VFVGNTPTDTISGDFSMLTYN------- MSMEG_4365|M.smegmatis_MC2_155 IMWDGGEWNGQ--RFVHTAFGDTFSGPNMSGWWRSNVLLISTDNVLSDGL TH_2316|M.thermoresistible__bu IMWDMGEWRGQ--RAVHVVFGDTFSGPNMSGDWISNAIMISTSRTLYENP MMAR_2591|M.marinum_M VKATSFGLNNI--ATVATAGGSGNTTVAAEASGAENVAVLATAFGNNNPT MUL_3169|M.ulcerans_Agy99 VKATSFGLNNI--ATVATAGGSGNTTVAAEASGAENVAVLATAFGNNNPT Mflv_0506|M.gilvum_PYR-GCK PKVVTGVTPPA--HGTVTAIGPSLSYTPAADFDGTDAFTYTLNDGSTATV Mvan_3594|M.vanbaalenii_PYR-1 SQGITFSTDGS--RVFVADLAGSVKVIDTDSHEVVDSIILATG------- MAV_3172|M.avium_104 ---HSLDGVST--GQVALVVQPTFLYELLWNLLIFVALLYADR------- MAB_2960|M.abscessus_ATCC_1997 GQIHDDDPRDQGWYDRYHPYRQYYDWKFQNTNPVYSRSLWDQSHGIDP-- Mb0912|M.bovis_AF2122/97 ---------------------------IAGLP------------------ Rv0888|M.tuberculosis_H37Rv ---------------------------IAGLP------------------ MSMEG_4365|M.smegmatis_MC2_155 G---------LVQTGTAYQFIPASGRNLFGLF------------------ TH_2316|M.thermoresistible__bu AGF-------LEQTGPAFQFIP--GGQLLSWF------------------ MMAR_2591|M.marinum_M VTANVLGAGNLATAATALGNNNTINANVVGLENIATVATAGGNDNGVGAS MUL_3169|M.ulcerans_Agy99 VTANVLGAGNLATAATALGNNNTINANVVGLENIATVATAGGNDNGVGAS Mflv_0506|M.gilvum_PYR-GCK TVIVTPVDDKPVAVGDTVTVAEDSSPTVIDVLANDTDIDAGPKTITGVSQ Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 ----------------------------FPLSSAILP------------R Rv0888|M.tuberculosis_H37Rv ----------------------------FPLSSAILP------------R MSMEG_4365|M.smegmatis_MC2_155 ----------------------------GGSEVTVIPTAGVQIDGTQYVN TH_2316|M.thermoresistible__bu ----------------------------FPAEVTVIPTAGVHANGTQYVN MMAR_2591|M.marinum_M GVGVGGNIGNIATAFGNSNSQVSADASGAGGNLGTVATAFGNENNVTASA MUL_3169|M.ulcerans_Agy99 GVGVGGNIGNIATAFGNSNSQVSADASGAGGNLGTVATAFGNENNVTASA Mflv_0506|M.gilvum_PYR-GCK PAKGNVVVTGTTVIYTPTADFTGTDTFTYTLNGGATATVTVTVTPVDDAP Mvan_3594|M.vanbaalenii_PYR-1 ----------------------------APFDLAVSP---------DGTT MAV_3172|M.avium_104 -------------------------------------------------R MAB_2960|M.abscessus_ATCC_1997 ----------------------------SQYRDWNLNRNWDNPLERDWSP Mb0912|M.bovis_AF2122/97 FFYTKEIGKR--LNAYYVANVQEDFAYHQ----FLIKKSKMP-------- Rv0888|M.tuberculosis_H37Rv FFYTKEIGKR--LNAYYVANVQEDFAYHQ----FLIKKSKMP-------- MSMEG_4365|M.smegmatis_MC2_155 YMSVRSWDTPGRWTTNFSAISVYDPSTDT----WVLAPSTIRSAGWFRSS TH_2316|M.thermoresistible__bu YMSVRQWGVPGSWTTNFSAISRYDQATDT----WVTVPSSVRSAGWLRSS MMAR_2591|M.marinum_M FGAGNIGNVSSALFSNNNTISASSIGVEN----IGTVATSIGDNNTVSAT MUL_3169|M.ulcerans_Agy99 FGAGNIGNVSSALFSNNNTISASSIGVEN----IGTVATSIGDNNTVSAT Mflv_0506|M.gilvum_PYR-GCK VTVGDTATVAEDSGPTIIDVLANDTDIDAGPIAITAVTQPVDGTVTFTAS Mvan_3594|M.vanbaalenii_PYR-1 LFVARSGDGKLSVYDIATKTELTSIVANP---YLVDGAPTISASPDGTQL MAV_3172|M.avium_104 LTLGHGRLFALYVAGYCVGRFCVELLRDD--------------------- MAB_2960|M.abscessus_ATCC_1997 VARVADRPLLAEPVVNLDASLAQFITDDK------SARSSQDLIKDLSNK . Mb0912|M.bovis_AF2122/97 ------SQTPPEPPTLLWP----IGVPFSDGLNTLSEFKVQ--RLDRQT- Rv0888|M.tuberculosis_H37Rv ------SQTPPEPPTLLWP----IGVPFSDGLNTLSEFKVQ--RLDRQT- MSMEG_4365|M.smegmatis_MC2_155 TLYVPGSQNFQQAAYVLQP----EDQVGEDGIRYLYAFGTPSGRAGSAY- TH_2316|M.thermoresistible__bu TPYRAGDQNFQQMAYVLQP----VDQVGEDGVRYVYAFGTPSGRQGSVH- MMAR_2591|M.marinum_M NGLGLGGNIATVATALGGQNNTVSAETGTGGANIASVSTVLFGENNTSS- MUL_3169|M.ulcerans_Agy99 NGLGLGGNIATVATALGGQNNTVSAETGTGGANIASVSTVLFGENNTAS- Mflv_0506|M.gilvum_PYR-GCK EVTYTPGADFHGTDTFTYTLNGGATATVTVTVTPVDDAPVTVGDAVTVAE Mvan_3594|M.vanbaalenii_PYR-1 YWTDSGSDRVHVIALLAPNGDPVAGTPVVNAPNASGAVTGSVTVTDPEG- MAV_3172|M.avium_104 -------TATHIAGIRINS----FTSTFVFIGAVVYLMAAPKGREDPES- MAB_2960|M.abscessus_ATCC_1997 SARNFSKELAAQTPRPDRSTGPDAPAAVKPAAPPVLTAPVPVVPPKEVP- Mb0912|M.bovis_AF2122/97 --------------------------WYECTSDNCLTLKGFTYS------ Rv0888|M.tuberculosis_H37Rv --------------------------WYECTSDNCLTLKGFTYS------ MSMEG_4365|M.smegmatis_MC2_155 --------------------------LSRVPEDAVTDLSKYEYWDGNR-- TH_2316|M.thermoresistible__bu --------------------------LSRVPEEHITDVSKYEYWDGNA-- MMAR_2591|M.marinum_M --------------------------ASAIGAGNIANVATVLFSDNNTSN MUL_3169|M.ulcerans_Agy99 --------------------------ASAVGAGNIANVATVSFCDNNTSN Mflv_0506|M.gilvum_PYR-GCK DSGPTIIDVLVNDTDIDAGPIAITAVTQPVDGTVTFTASEVTYTPGADFH Mvan_3594|M.vanbaalenii_PYR-1 --------------------------RPLTYTVSTPDKGAVTVSRGEN-- MAV_3172|M.avium_104 -----------------------------LRGNQYVEEEPAEPEP----- MAB_2960|M.abscessus_ATCC_1997 ----------------------ADFTPPSLPPVAPVTPAPRTTSSAPSSA Mb0912|M.bovis_AF2122/97 -----QMRLPGGDTVDVYNLHTNTGGGPTTNANLAQVANYIQQN------ Rv0888|M.tuberculosis_H37Rv -----QMRLPGGDTVDVYNLHTNTGGGPTTNANLAQVANYIQQN------ MSMEG_4365|M.smegmatis_MC2_155 -----WVTGNAAVAAPVIGDSTRSTGLFGFIVDWANDPNVLGGY------ TH_2316|M.thermoresistible__bu -----WVS-SAAHAAPIIGESTRSAGLFGFIIDWANDPNVFGGY------ MMAR_2591|M.marinum_M ASSFGVENIAAVATSYGDGNTVTATNSLGLGGNIATVATALGGQDNTVSA MUL_3169|M.ulcerans_Agy99 ASSFGVENIAAVATSYGDGNTVTATNSLGLGGNIATVATALGGQDNTVSA Mflv_0506|M.gilvum_PYR-GCK GTDTFTYTLNGGSVAVVTVIVDRVDDTPIAFGDSVTVAEDSGPTTIDVLA Mvan_3594|M.vanbaalenii_PYR-1 ----GDFVFTYTPTAAARHAAAAVSGAPGAAVDTFTVTFSDGRR------ MAV_3172|M.avium_104 ------ATVAATTEAATEGVAAPADGAEAAGADATAQRPEESAEP----- MAB_2960|M.abscessus_ATCC_1997 PSTEPSHTPEPSSEPPANGTTSNPGPTPTSVAPAPTQKDESSAP------ Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M QAGAGGANIAQVATVLFGDNNTASASGLGAGNIADVATVLFSNNNTSTAS MUL_3169|M.ulcerans_Agy99 QAGAG--------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK NDTDIDNGPIAITAVTQPTNGTIDFTVSRVTYTPGANFHGTDTFTYTLNG Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M ALGVENIATIATSYGDNNNVSATAPGIGANIATVATALGGQGNTVSAESG MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK GATATVTVTVNAAPVIGQVTTTPGVGNTWEVSVSADDSENDTLTTTVTSA Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M GAGANIASVSTVLFGENNTSSASAIGAGNIANVATVLFSDNNTSNASSFG MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK DPTVPLTVTKQTDGTFQVVADPTWASAHPAAQIAVTVTVTDTYGSSATIT Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M VENIAAVATSYGDGNTVTATNSLGLGGNIATVATALGGQDNTVSAQAGAG MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK TAIGTANNVISLGWDATGVGNVPALPAGVSYTQVAGGAFHTVFLRSDGSV Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M G------------ANIAQVATVLFGDNNTASASGLGAGNIADVATVLFSN MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK VGAGQNNYGQLDIPPLPTGITYTQVAAGAWHTVLLRSDGTVVAVGDNFKG Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M NNTSTASALGVENIATIATSYGDNNNVSATAPGIGANIATVATALGGQGN MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK QIDIPEPGLGVSYTGVAAGELGTILLRSDGTAVAVGDGQYGQLEIPTLPP Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M TVSAESGGAGANIASVSTVLFGENNTSSASAIGAGNIANVATVLFSDNNT MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK GVRYTQAAIGSVRSALLRSDGTVVTVGMNDAVPTLPAGVRYISVASGAGH Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M SNASSFGVENIAAVATSYGDGNTVTATNSLGLGGNIATVATALGGQDNTV MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK AVLLRSDGVAVAFGANDWGQTDIPALPAGVVYVNIAASRYHSVLLRSDGT Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -----------------------SAGRAV-----IVTG----DFNARYSD Rv0888|M.tuberculosis_H37Rv -----------------------SAGRAV-----IVTG----DFNARYSD MSMEG_4365|M.smegmatis_MC2_155 -----------------------LGGLVG-----AKTGGNVSELSVQYNE TH_2316|M.thermoresistible__bu -----------------------LGGLFG-----AKTGGNVGEMSVQYNE MMAR_2591|M.marinum_M SAQAGAGGANIAQVATVLFGDNNTASASG-----LGAGNIADVATVLFSN MUL_3169|M.ulcerans_Agy99 -------GANIAQVATVLFGDNNTASASG-----LGAGNIADVATVLFSN Mflv_0506|M.gilvum_PYR-GCK SVAAGQNTSEQLDIPVLPVGVTYTGGAAGGYSTWLISSTTATPFNTPPVA Mvan_3594|M.vanbaalenii_PYR-1 -------------------------GVVS-----VPITVTIAPANAAPTA MAV_3172|M.avium_104 -------------------------DVEK-----PESEETEAEAAEEPES MAB_2960|M.abscessus_ATCC_1997 ----------------------VTTAVTP----THETPATTAPRQTATVP Mb0912|M.bovis_AF2122/97 DQSALLQFAQVNGLTDAWVQVEHGPTTPPFAP------------------ Rv0888|M.tuberculosis_H37Rv DQSALLQFAQVNGLTDAWVQVEHGPTTPPFAP------------------ MSMEG_4365|M.smegmatis_MC2_155 YLGKYVVLYGDG-NNNIQMRIADRPEGPWSDP------------------ TH_2316|M.thermoresistible__bu YLGKYVILYGNGRTNNIEMRIADSPEGPWSDP------------------ MMAR_2591|M.marinum_M NNTSTASALGVENIATIATSYGDNNNVSATAPGIGANIATVATALGGQGN MUL_3169|M.ulcerans_Agy99 NNTSTASALGVENIATIVTSYGDNNNVSATAPGIGANIATVATALGGQGN Mflv_0506|M.gilvum_PYR-GCK VDDAMTVAEGNTATISVTANDTDADGTIDTATVVITRQSTAGSVAVNAAG Mvan_3594|M.vanbaalenii_PYR-1 TARSSLSWFSPKVYGTVTAKDADKDTLGFTASP----------------- MAV_3172|M.avium_104 EETEAAEEPGEPEAEEPEEPEAEEPEEPETEE------------------ MAB_2960|M.abscessus_ATCC_1997 PSQPVEPTTAPEPTKQHSTPTHDVPTSEAPAPR----------------- . Mb0912|M.bovis_AF2122/97 ----TCMVG-NECELLDKIFYRSGQGVTLQAVSYGNEA-------PKFFN Rv0888|M.tuberculosis_H37Rv ----TCMVG-NECELLDKIFYRSGQGVTLQAVSYGNEA-------PKFFN MSMEG_4365|M.smegmatis_MC2_155 ----IELASSADYPGLYAPMIHPWSGTGMLEDDNGDPD-------VNNLY TH_2316|M.thermoresistible__bu ----IILATPQQYPGLYAPMIHPWSGTGYLLDENGDPD-------PESLY MMAR_2591|M.marinum_M TVSAESGGAGANIASVSTVLFGENNTASASAIGAGNIANVATVLFSDNNT MUL_3169|M.ulcerans_Agy99 TVSAESGGAGANIASVSTVLFGENNTASASAVGAGNIANVATVLFSDSNT Mflv_0506|M.gilvum_PYR-GCK TVTYVSNGTEVTADSFAYRIDDALGATSNEATVFITITPVDDAPVAVNDA Mvan_3594|M.vanbaalenii_PYR-1 ----TAKGGTVTIDADGKFTYTPTAAARHAAANAGATEADKHDTFTVLVD MAV_3172|M.avium_104 ----------PEADSDEEPEEESGEAPEQPVAEEPEPAP--------QQP MAB_2960|M.abscessus_ATCC_1997 ---ATAEPAPAEPPAKQAPAERETPPSRTAAPEPAAPTREAPAREAPTRE Mb0912|M.bovis_AF2122/97 SKGEPLSDHSPAVVGFHYVADNVAVR------------------------ Rv0888|M.tuberculosis_H37Rv SKGEPLSDHSPAVVGFHYVADNVAVR------------------------ MSMEG_4365|M.smegmatis_MC2_155 WNMSLWGDYNVVLMQTDLSGLKTVAV------------------------ TH_2316|M.thermoresistible__bu WNMSMWGPYNVYLMQTDLSSLVEV-------------------------- MMAR_2591|M.marinum_M STVSSFGVENIATVATSYGDFNNVSASTPGIGGNIATFATAFGEGNTNVH MUL_3169|M.ulcerans_Agy99 STVSSFGVENIATVATSYGDFNNVSARTPGIGGNIATFATAFGEGNTNVH Mflv_0506|M.gilvum_PYR-GCK VTVAEGGTITIAVIGNDTDADGTIDTTTVVIVTQPTAGTATVNGDGTVTY Mvan_3594|M.vanbaalenii_PYR-1 DGHGGVTPLTVTVKVKPGNATPTATVRTS---------SSWFSAKVYGTV MAV_3172|M.avium_104 ETKRRWGARLRDRLSGR--------------------------------- MAB_2960|M.abscessus_ATCC_1997 APSYSTATQAPSAGGGNSGGGSGGGRH----------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M AEAGPGGANIATLATVFGDGNAVS-------------------------- MUL_3169|M.ulcerans_Agy99 AEAGPGGANIATLATVFGDGNAVS-------------------------- Mflv_0506|M.gilvum_PYR-GCK VSDGSEVTSDSFTYTVKDTAGLTSNVATVSITVNPVNDAPVAVNDAYTVA Mvan_3594|M.vanbaalenii_PYR-1 TAKDLDRDGLAYTASATAKGG----------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------VKSIGAGNTASIATMIGNNNTADIN MUL_3169|M.ulcerans_Agy99 -------------------------VKSIGAGNTASIATMIGNNNTADIN Mflv_0506|M.gilvum_PYR-GCK ENGLLVIDAPGLLGNDLDSEHPFIYITTITNPRHGTFDGILSDGSFTYRP Mvan_3594|M.vanbaalenii_PYR-1 -------------------------TVTIDGRGRFTYTPSDAARHVAAAE MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M VFGLENVATVATAIGDNNGLTANAPGLGANIATVATAIGSGNSQVSAEAG MUL_3169|M.ulcerans_Agy99 VFGLENVATVATAIGDNNGLTANAPGLGANIATVATAIGSGNSQVSAEAG Mflv_0506|M.gilvum_PYR-GCK HAGYFGTDSFTYQINDVTGLTSNTATVTITITPVDDAPVAVNDAVTVAED Mvan_3594|M.vanbaalenii_PYR-1 AATREDKQDTFDVVIDDGHGGVATVAVTVNIKPANAAPTDAATADVFTNP MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M GAGGNIATLSSVFGDSNTAVVTAFGAGNVPTAATVFGSGNGVKVNSFGLE MUL_3169|M.ulcerans_Agy99 GAGGNIATLSSVFGDNNTAVVTAFGAS----------------------- Mflv_0506|M.gilvum_PYR-GCK SGTTVIDVLANDTDIDAGPKTITSITQPNSGTTTITATGVAYTPNENFHG Mvan_3594|M.vanbaalenii_PYR-1 NSGVITG------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M NIATLGTVFGDNNTGVVADAGGVGGNIATLANVIGDGNTAAAASAVGTGN MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK TDTFTYTLNGGTSAEVTVTVTPVNDAPVAPDKVVTISEDTWSVAIHLTDG Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M IATLANVFGDANAATAGSIGVGNVPTAATVFGSGNGVTVSTFGLENIATL MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK ATDVDGDPLRRGYVTYPAIGSTFVDSDNLGIQRLLRYYPPANYTGQITIP Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M GTVIGDNNTGVVADAGGVGGNIATLANVIGNNNTAAGASAVGTGNIATLA MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK YTVWDGQVFSNWATITINVTPVNDVPVAVNDSAAVDAGGTTTITLTANDT Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M NVFGDANAATAGSIGVGNVPTAATVFGSGNGVKVSTFGLENIATLGTVIG MUL_3169|M.ulcerans_Agy99 -----------------NVPTAATVFGSGNGVKVSTFGLENIATLGTVIG Mflv_0506|M.gilvum_PYR-GCK DVDTDNGVDPATIVIGTQPSAGTVTVNSDGTVTYTSTGTTTTTDIFTYTV Mvan_3594|M.vanbaalenii_PYR-1 --------------------------------KITAVDADGDAVTYRAAP MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M DNNTGVVADAGGVGGNIATLANVFGNDNTAAEATASGVGGNIATLANVFG MUL_3169|M.ulcerans_Agy99 DNNTGVVADAGGVGGNIATLANVFGNDNTAAEATASGVGGNIATLANVFG Mflv_0506|M.gilvum_PYR-GCK EDTTGLVSNPATVTVNVTATATPPVAVNDTVTVDEGGTTTLAVIANDTDA Mvan_3594|M.vanbaalenii_PYR-1 ATSKGVVSIDADGTFTYVPTAEARTAASRPFAPSWDKNDRFRVTVDDGHG MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M DGNAVKANVVGFGNVPSAATVIGSNNTVTTDVFGVENIATLASVYGDGNS MUL_3169|M.ulcerans_Agy99 DGNAVKANVVGFGNVPSAATVIGSNNTVTTDVFGVENIATLASVYGDGNS Mflv_0506|M.gilvum_PYR-GCK DGDIDTATVVIVRQPTAGTATVNSDGTVSYASDGSEITTDSFEYTVRDVA Mvan_3594|M.vanbaalenii_PYR-1 GTTTLTVRVAIAPLGHVNQAPTNGSYSVGQPNPASGKVAGTVSATDPERD MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M GVLAQSGGVGGNIATLATVIGSNNTATEASAVGIGGNIATLG--TALSDG MUL_3169|M.ulcerans_Agy99 GVLAQSGGVGGNIATLATVIGSNNTATEASAVGIGGNTATLG--TALSDG Mflv_0506|M.gilvum_PYR-GCK GAVSNAATVIITVTPVDDAPVAVNDTVTITEDTLATFIDVLANDTDIDGG Mvan_3594|M.vanbaalenii_PYR-1 AVTFAGSGVTG-------------------------------------NG MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M NAVSATANGFGNTATVATAFIGGGNTATASASGVGNIASLATAVGADNAV MUL_3169|M.ulcerans_Agy99 NAVSATANGFGNTATVATAFIGGGNTATASASGVGNIASLATAVGADNAV Mflv_0506|M.gilvum_PYR-GCK PKTITSITSPAGGHALVIGNRVRYFSAPNFHGTETFTYTLNGGATATVTV Mvan_3594|M.vanbaalenii_PYR-1 SVIVDAAGGFVYTPSDEARHRAGADDATQADKQDTFTVTAVDFYGAKLAV MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M SATASGAGGNIAIAATAIGDGNTEVTADAGGLGGNIGVAATAIGGGNTVA MUL_3169|M.ulcerans_Agy99 SATASGAGGNIAIAATAIGDGNTEVTADAGGLGGNIGVAATAIGGGNTVA Mflv_0506|M.gilvum_PYR-GCK IVTPISEAPVIHRVTSTPGVGNTWVLSVDASDDDGGALTTTVTSANATVP Mvan_3594|M.vanbaalenii_PYR-1 PVTVTIVGLTAL-------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M ASSTGLTIGSVATAVGDGNTGIAARGHQAGNLGIVSTAIGFGNTDVAAAG MUL_3169|M.ulcerans_Agy99 ASSTGLTIGSVATAVGDGNTGIAARGHQAGNLGIVSTAIGFGNTDVAAAG Mflv_0506|M.gilvum_PYR-GCK LTITRLPGGAIQVDIDPTWARAHPGAQLPVTVTVTDAENISATKQLTIGT Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M FG--------VANIGNVATVIGSNNQNVFAGGTGLSNIATVGGDNNTALA MUL_3169|M.ulcerans_Agy99 FG--------VANIGNVATVIGSNNQNVFAGGTGLSNIATVGGDNNTALA Mflv_0506|M.gilvum_PYR-GCK VSNAVFFGHNIYGQRNIPALPEGVTYTQVATASLSHTVLLRSDGTAVAVG Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M GDQSGGLASVNVATVFGSGSGASAFNGFLNLAIGLTDGVMASAGPGNFNV MUL_3169|M.ulcerans_Agy99 GDQSGGLASVNVATVFGSGSGASAFNGFLNLAIGLTDGVMASAGPGNFNV Mflv_0506|M.gilvum_PYR-GCK DNFRGQLNIPPLPTGMTYTQVANGTEHTVLLRSDGTAIAVGNNSDGQLNI Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M SIQPFFDVQPLFG------------------------------------- MUL_3169|M.ulcerans_Agy99 SIHPFFDVQPLFG------------------------------------- Mflv_0506|M.gilvum_PYR-GCK PRLPAGVTYTRIAAGNYGTVLLRSDGTAVGAGYNTYGQLNIPQPPPGVTY Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK TQAAVGLTHTVLLRSDGTAVALGDNAFGQTVIPALPTGLKYTQVAAGDLH Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK SVLLRSDGSVVAFGNNQWGQSTVPALPAGLRYTQVAAGRYNSMLLRSDGT Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK AIGFGQNASSQLNIPVLPAGLVYTQAAASNHTVLLFSTSSSFNSLPLATN Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK DAATVAEGGTITFSVTANDTDTDGTLNTATVVITRQPTSGSVTVNAGGTV Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK TYVSNGAEVSADSFAYRVNDNKGATSNEATVSITITPVNDAPVAVDDAYT Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK VAKNGVLVISAPGLLANDSDPEGNSFTIVAATGTQHGTVDPLYSNGSFTY Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK RPAAGYSGTDTFTYTISDGTSTAQATVTIAVSAVDNQAPVAVADSYTVAE Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK DGVLNVTGPGVLANDTDADGDPLSVVAAGPTSHGTFTLRSDGSFTYTPVA Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK NFHGTDSFTYQVSDGSGPSAPATVTITVTPVNDAPVVQNDTIPFPKDGFI Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 -------------------------------------------------- Rv0888|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_4365|M.smegmatis_MC2_155 -------------------------------------------------- TH_2316|M.thermoresistible__bu -------------------------------------------------- MMAR_2591|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 -------------------------------------------------- Mflv_0506|M.gilvum_PYR-GCK GFSLANRSSDVDGDTLTATLISGTTHGTLFFDGTNRAFSYRPNTGFTGQD Mvan_3594|M.vanbaalenii_PYR-1 -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MAB_2960|M.abscessus_ATCC_1997 -------------------------------------------------- Mb0912|M.bovis_AF2122/97 ----------------------- Rv0888|M.tuberculosis_H37Rv ----------------------- MSMEG_4365|M.smegmatis_MC2_155 ----------------------- TH_2316|M.thermoresistible__bu ----------------------- MMAR_2591|M.marinum_M ----------------------- MUL_3169|M.ulcerans_Agy99 ----------------------- Mflv_0506|M.gilvum_PYR-GCK SFTYKVNDGTVDSAIATVTLNVS Mvan_3594|M.vanbaalenii_PYR-1 ----------------------- MAV_3172|M.avium_104 ----------------------- MAB_2960|M.abscessus_ATCC_1997 -----------------------