For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TDSIAPDTHPHLRHDLSIDQRLALKAAATHLETEFDGMYGMETIERFLHSSYDQFAGRASIPNFLPLLAE RFARQRLRALAKIEGKHHDGKPTVLFLCTHNAGRSQMAMGFFTHLAGDAAVAWSGGSEPGNEVNPAAVAA MAECNIDISREYPKPWTDEIVRAADVIITMGCGDACPVFPGLRYEEWKLEDPHGQGVDAVRPIRDEIERR VRALLSELDVPVQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1659 | - | - | 100% (225) | protein tyrosine phosphatase |
| M. gilvum PYR-GCK | Mflv_3468 | - | 2e-50 | 69.40% (134) | protein tyrosine phosphatase |
| M. gilvum PYR-GCK | Mflv_1656 | - | 3e-22 | 38.93% (131) | protein tyrosine phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2676 | arsC | 2e-41 | 58.27% (139) | arsenic-transport integral membrane protein ArsC |
| M. tuberculosis H37Rv | Rv2643 | arsC | 1e-41 | 58.27% (139) | arsenic-transport integral membrane protein ArsC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4842 | - | 9e-87 | 73.30% (206) | putative arsenate reductase ArsC |
| M. marinum M | MMAR_2055 | arsC | 5e-42 | 59.40% (133) | arsenic-transport integral membrane protein ArsC |
| M. avium 104 | MAV_1496 | - | 5e-94 | 73.76% (221) | low molecular weight phosphotyrosine protein phosphatase |
| M. smegmatis MC2 155 | MSMEG_1171 | - | 2e-58 | 78.29% (129) | low molecular weight phosphotyrosine protein phosphatase |
| M. thermoresistible (build 8) | TH_1049 | arsC | 2e-40 | 58.46% (130) | PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSC |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5094 | - | 1e-110 | 86.61% (224) | protein tyrosine phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5094|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
Rv2643|M.tuberculosis_H37Rv MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
MMAR_2055|M.marinum_M MTGTVDHQPAPAVVGKLSTLDRFLPVWIGLAMAAGLLLGRWIPGLNTALE
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5094|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
Rv2643|M.tuberculosis_H37Rv GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
MMAR_2055|M.marinum_M KVQVDGISLPIALGLLIMMYPVLAKVRYDRLDSVTGDRKLLISSLLLNWV
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5094|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
Rv2643|M.tuberculosis_H37Rv LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MMAR_2055|M.marinum_M AGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLARGDREAA
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5094|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
Rv2643|M.tuberculosis_H37Rv AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
MMAR_2055|M.marinum_M AVLVALNSIFQVAMFAVLGWFYLSVLPGWLHLTQTTISTSPWQIAKSVLI
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5094|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
Rv2643|M.tuberculosis_H37Rv FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
MMAR_2055|M.marinum_M FLGIPLLAGYLSRRLGERAKGRGWYESRFLPKVGPWALYGLLFTIVILFA
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK -MTDSIAPDTHPHLRHDLS--------------IDQRLALKAAATHLETE
Mvan_5094|M.vanbaalenii_PYR-1 -MTGSTAPEAHPQLRRDLS--------------IDQRLALKSAATQLEKE
MAB_4842|M.abscessus_ATCC_1997 -MTGQASTEP----RQELT--------------LDQVHALKTAATRLQQE
MAV_1496|M.avium_104 -MTDSPASLA-AHVRRDIS--------------IDQQLALRTASTRLHDD
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
Rv2643|M.tuberculosis_H37Rv LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
MMAR_2055|M.marinum_M LQGDQITNRPQDVARIALPLLVYFAVMWGGGYLLGAALHLGYQRTTTMAF
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK FDGMYGMETIERFLHSSYDQFAGRASIPNFLPLLAERFAR--------QR
Mvan_5094|M.vanbaalenii_PYR-1 FDGIYGVETIELFLHSSYDQFAGRASIVNFLPLLAERFAR--------QR
MAB_4842|M.abscessus_ATCC_1997 FEGTFGTETIERFLQSSYGQFAGRASVSRFLPLLAERFAR--------QR
MAV_1496|M.avium_104 FAEHFGVETIERFLHSSYDQFAGRATVPNFLPLLAERWAR--------QR
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
Rv2643|M.tuberculosis_H37Rv TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
MMAR_2055|M.marinum_M TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
TH_1049|M.thermoresistible__bu --------------MTSDSAT-----------------------------
Mflv_1659|M.gilvum_PYR-GCK LRALAKIEGKHHDGKPTVLFLCTHNAGRSQMAMGFFTHLAGDAAVAWSGG
Mvan_5094|M.vanbaalenii_PYR-1 LRALAKVEGKSQDGKPTVLFLCTHNAGRSQMAMGFFTALAGDAAVAWSGG
MAB_4842|M.abscessus_ATCC_1997 LRALARVEGKSADGRPTVLFLCIHNAGRSQMALGFFQAVAGDSAVAWSGG
MAV_1496|M.avium_104 LTALARVEGKVTDTKPTVLFLCTHNAGRSQMALGYFNHLAGDQGVAWSGG
MSMEG_1171|M.smegmatis_MC2_155 ------MTG------PTVLFLCTHNAGRSQMALGYFTHLAGDGAVAWSGG
Mb2676|M.bovis_AF2122/97 NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
Rv2643|M.tuberculosis_H37Rv NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
MMAR_2055|M.marinum_M NRYYGPHRRKHDMIKPSVLFVCVHNAGRSQMAAGWLRHLAGDRIEVRSAG
TH_1049|M.thermoresistible__bu -----------DNPTPSVLFVCVHNAGRSQMAAGFLTALAGGRIEVRSAG
*:***:* ********* * : :**. . *.*
Mflv_1659|M.gilvum_PYR-GCK SEPGNEVNPAAVAAMAECNIDISREYPKPWTDEIVRAADVIITMGCGDAC
Mvan_5094|M.vanbaalenii_PYR-1 SEPGDEVNPAAVEAMAERGIDISREYPKPWTEEIVRAADVIITMGCGDAC
MAB_4842|M.abscessus_ATCC_1997 SEPGTEVNAIAIAAMAERGIDISGEYPKPWTDEVVQAADVVVTMGCGDAC
MAV_1496|M.avium_104 SEPGNEINPAAVQAMAEVGIDITREFPKPWTDEIVQASDVVVTMGCGDAC
MSMEG_1171|M.smegmatis_MC2_155 SEPAAEINPVAVAAMAEVGIDITGEYPKPWTDEIVRVADVVITMGCGDTC
Mb2676|M.bovis_AF2122/97 TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
Rv2643|M.tuberculosis_H37Rv TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
MMAR_2055|M.marinum_M TEPADRINPVAVAAMAELGIDITANTPEVLTGAWVQTSDVVITMGCGDAC
TH_1049|M.thermoresistible__bu SAPADQLNPAAVEAMAEVGIDISTHQPKVLTTDAVQASDVVITMGCGDTC
: *. .:*. *: **** .***: . * * *: :**::******:*
Mflv_1659|M.gilvum_PYR-GCK PVFPGLRYEEWKLEDPHGQGVDAVRPIRDEIERRVRALLSELD----VPV
Mvan_5094|M.vanbaalenii_PYR-1 PVFPGRRYEEWKLDDPAGQSVDDVRPIRDEIERRVRTLLVELD----VPA
MAB_4842|M.abscessus_ATCC_1997 PVFPGRRYLDWTLDDPTGLDVEGLRPIRDEIERRVRHLVDELL----GAR
MAV_1496|M.avium_104 PFFPGKRYENWDLTDPAGQGVDVVRPIRDEIESRVRRLLAELH----ITP
MSMEG_1171|M.smegmatis_MC2_155 PVYPGKRYENWELPDPAGQALDAVRPIRDDIEHRVRRLLADLG----VAT
Mb2676|M.bovis_AF2122/97 PYFPGASYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAEL-----LAT
Rv2643|M.tuberculosis_H37Rv PYFPGVSYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAEL-----LAT
MMAR_2055|M.marinum_M PYFPGVSYRDWTLADPAGQPLDVVRPIRDDIGERVRALIAEL-----LNE
TH_1049|M.thermoresistible__bu PIFPGRSYRDWVLDDPAGKDLDDVRRIRDDIKARVEDLIAELDPPPDLNA
* :** * :* * ** * :: :* ***:* **. *: :*
Mflv_1659|M.gilvum_PYR-GCK QS-------------
Mvan_5094|M.vanbaalenii_PYR-1 QG-------------
MAB_4842|M.abscessus_ATCC_1997 Q--------------
MAV_1496|M.avium_104 VS-------------
MSMEG_1171|M.smegmatis_MC2_155 IR-------------
Mb2676|M.bovis_AF2122/97 AKTR-----------
Rv2643|M.tuberculosis_H37Rv AKTR-----------
MMAR_2055|M.marinum_M HPDTAQICRG-----
TH_1049|M.thermoresistible__bu RDRPVPATRAGTTTR