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MTDSPASLAAHVRRDISIDQQLALRTASTRLHDDFAEHFGVETIERFLHSSYDQFAGRATVPNFLPLLAE RWARQRLTALARVEGKVTDTKPTVLFLCTHNAGRSQMALGYFNHLAGDQGVAWSGGSEPGNEINPAAVQA MAEVGIDITREFPKPWTDEIVQASDVVVTMGCGDACPFFPGKRYENWDLTDPAGQGVDVVRPIRDEIESR VRRLLAELHITPVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1496 | - | - | 100% (224) | low molecular weight phosphotyrosine protein phosphatase |
| M. avium 104 | MAV_1497 | - | 6e-19 | 37.90% (124) | low molecular weight phosphotyrosine protein phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2676 | arsC | 4e-43 | 62.60% (131) | arsenic-transport integral membrane protein ArsC |
| M. gilvum PYR-GCK | Mflv_1659 | - | 5e-94 | 73.76% (221) | protein tyrosine phosphatase |
| M. tuberculosis H37Rv | Rv2643 | arsC | 5e-43 | 62.60% (131) | arsenic-transport integral membrane protein ArsC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4842 | - | 1e-81 | 69.90% (206) | putative arsenate reductase ArsC |
| M. marinum M | MMAR_2055 | arsC | 2e-44 | 64.84% (128) | arsenic-transport integral membrane protein ArsC |
| M. smegmatis MC2 155 | MSMEG_1171 | - | 2e-60 | 77.61% (134) | low molecular weight phosphotyrosine protein phosphatase |
| M. thermoresistible (build 8) | TH_1049 | arsC | 6e-41 | 59.54% (131) | PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSC |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3221 | - | 4e-95 | 74.55% (220) | protein tyrosine phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
Rv2643|M.tuberculosis_H37Rv MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
MMAR_2055|M.marinum_M MTGTVDHQPAPAVVGKLSTLDRFLPVWIGLAMAAGLLLGRWIPGLNTALE
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
Rv2643|M.tuberculosis_H37Rv GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
MMAR_2055|M.marinum_M KVQVDGISLPIALGLLIMMYPVLAKVRYDRLDSVTGDRKLLISSLLLNWV
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
Rv2643|M.tuberculosis_H37Rv LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MMAR_2055|M.marinum_M AGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLARGDREAA
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
Rv2643|M.tuberculosis_H37Rv AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
MMAR_2055|M.marinum_M AVLVALNSIFQVAMFAVLGWFYLSVLPGWLHLTQTTISTSPWQIAKSVLI
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4842|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
Rv2643|M.tuberculosis_H37Rv FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
MMAR_2055|M.marinum_M FLGIPLLAGYLSRRLGERAKGRGWYESRFLPKVGPWALYGLLFTIVILFA
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK -MTDSIAPDTHPHLRHDLSIDQRLALK-------AAATHLETEFDGMYGM
MAB_4842|M.abscessus_ATCC_1997 -MTG--QASTEP--RQELTLDQVHALK-------TAATRLQQEFEGTFGT
MAV_1496|M.avium_104 -MTDS-PASLAAHVRRDISIDQQLALR-------TASTRLHDDFAEHFGV
Mvan_3221|M.vanbaalenii_PYR-1 -MTDT---PVTHQLRRDLPIDQQLALK-------AAANQLQTEFGDTIGA
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
Rv2643|M.tuberculosis_H37Rv LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
MMAR_2055|M.marinum_M LQGDQITNRPQDVARIALPLLVYFAVMWGGGYLLGAALHLGYQRTTTMAF
TH_1049|M.thermoresistible__bu --------------------------------------------------
Mflv_1659|M.gilvum_PYR-GCK ETIER-------FLHSSYDQFAGRASIPNFLPLLAER----FARQRLRAL
MAB_4842|M.abscessus_ATCC_1997 ETIER-------FLQSSYGQFAGRASVSRFLPLLAER----FARQRLRAL
MAV_1496|M.avium_104 ETIER-------FLHSSYDQFAGRATVPNFLPLLAER----WARQRLTAL
Mvan_3221|M.vanbaalenii_PYR-1 ETIER-------FLHSSYAHFAGRAKVPNFLPLLAER----YARQQLSAL
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
Rv2643|M.tuberculosis_H37Rv TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
MMAR_2055|M.marinum_M TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
TH_1049|M.thermoresistible__bu --------------MTSDSAT-----------------------------
Mflv_1659|M.gilvum_PYR-GCK AKIEGKH----HDGKPTVLFLCTHNAGRSQMAMGFFTHLAGDAAVAWSGG
MAB_4842|M.abscessus_ATCC_1997 ARVEGKS----ADGRPTVLFLCIHNAGRSQMALGFFQAVAGDSAVAWSGG
MAV_1496|M.avium_104 ARVEGKV----TDTKPTVLFLCTHNAGRSQMALGYFNHLAGDQGVAWSGG
Mvan_3221|M.vanbaalenii_PYR-1 ARVEAKI----PDGKPTVLFLCTHNAGRSQMALGFLTHLAGDKVVGWSGG
MSMEG_1171|M.smegmatis_MC2_155 --MTG----------PTVLFLCTHNAGRSQMALGYFTHLAGDGAVAWSGG
Mb2676|M.bovis_AF2122/97 NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
Rv2643|M.tuberculosis_H37Rv NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
MMAR_2055|M.marinum_M NRYYGPHRRKHDMIKPSVLFVCVHNAGRSQMAAGWLRHLAGDRIEVRSAG
TH_1049|M.thermoresistible__bu -----------DNPTPSVLFVCVHNAGRSQMAAGFLTALAGGRIEVRSAG
*:***:* ********* * : :**. *.*
Mflv_1659|M.gilvum_PYR-GCK SEPGNEVNPAAVAAMAECNIDISREYPKPWTDEIVRAADVIITMGCGDAC
MAB_4842|M.abscessus_ATCC_1997 SEPGTEVNAIAIAAMAERGIDISGEYPKPWTDEVVQAADVVVTMGCGDAC
MAV_1496|M.avium_104 SEPGNEINPAAVQAMAEVGIDITREFPKPWTDEIVQASDVVVTMGCGDAC
Mvan_3221|M.vanbaalenii_PYR-1 SEPGHEINPAAVAAMAEVGIDITGEFPKPWTEEIVRAADVVVTMGCGDAC
MSMEG_1171|M.smegmatis_MC2_155 SEPAAEINPVAVAAMAEVGIDITGEYPKPWTDEIVRVADVVITMGCGDTC
Mb2676|M.bovis_AF2122/97 TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
Rv2643|M.tuberculosis_H37Rv TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
MMAR_2055|M.marinum_M TEPADRINPVAVAAMAELGIDITANTPEVLTGAWVQTSDVVITMGCGDAC
TH_1049|M.thermoresistible__bu SAPADQLNPAAVEAMAEVGIDISTHQPKVLTTDAVQASDVVITMGCGDTC
: *. .:*. *: **** .***: . * * *: :**::******:*
Mflv_1659|M.gilvum_PYR-GCK PVFPGLRYEEWKLEDPHGQGVDAVRPIRDEIERRVRALLSEL-----DVP
MAB_4842|M.abscessus_ATCC_1997 PVFPGRRYLDWTLDDPTGLDVEGLRPIRDEIERRVRHLVDEL-----LGA
MAV_1496|M.avium_104 PFFPGKRYENWDLTDPAGQGVDVVRPIRDEIESRVRRLLAEL-----HIT
Mvan_3221|M.vanbaalenii_PYR-1 PVFPGKRYENWELTDPAGQGLEAVRPIRDDVEERVRRLLADL-----QVP
MSMEG_1171|M.smegmatis_MC2_155 PVYPGKRYENWELPDPAGQALDAVRPIRDDIEHRVRRLLADL-----GVA
Mb2676|M.bovis_AF2122/97 PYFPGASYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAEL-----LAT
Rv2643|M.tuberculosis_H37Rv PYFPGVSYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAEL-----LAT
MMAR_2055|M.marinum_M PYFPGVSYRDWTLADPAGQPLDVVRPIRDDIGERVRALIAEL-----LNE
TH_1049|M.thermoresistible__bu PIFPGRSYRDWVLDDPAGKDLDDVRRIRDDIKARVEDLIAELDPPPDLNA
* :** * :* * ** * :: :* ***:: **. *: :*
Mflv_1659|M.gilvum_PYR-GCK VQS------------
MAB_4842|M.abscessus_ATCC_1997 RQ-------------
MAV_1496|M.avium_104 PVS------------
Mvan_3221|M.vanbaalenii_PYR-1 VAVR-----------
MSMEG_1171|M.smegmatis_MC2_155 TIR------------
Mb2676|M.bovis_AF2122/97 AKTR-----------
Rv2643|M.tuberculosis_H37Rv AKTR-----------
MMAR_2055|M.marinum_M HPDTAQICRG-----
TH_1049|M.thermoresistible__bu RDRPVPATRAGTTTR