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TPKPSVLFVCVKNGGKSQMAAGLMRRLAGEEIDVYSAGTAPGAAVNALSAESLREVGIDISGEKPKQVDP QRVRQVDMVVTLGREAQVEPVPGTRFENWDTDEPAERGIDGIERMRLVRDDIATRVGRLAEQLRTAARLH PEENAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1656 | - | - | 100% (147) | protein tyrosine phosphatase |
| M. gilvum PYR-GCK | Mflv_3468 | - | 3e-27 | 44.27% (131) | protein tyrosine phosphatase |
| M. gilvum PYR-GCK | Mflv_1659 | - | 1e-22 | 38.93% (131) | protein tyrosine phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2676 | arsC | 1e-26 | 43.38% (136) | arsenic-transport integral membrane protein ArsC |
| M. tuberculosis H37Rv | Rv2643 | arsC | 1e-26 | 43.38% (136) | arsenic-transport integral membrane protein ArsC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4864 | - | 3e-48 | 67.16% (134) | putative arsenate reductase |
| M. marinum M | MMAR_2055 | arsC | 7e-24 | 41.98% (131) | arsenic-transport integral membrane protein ArsC |
| M. avium 104 | MAV_1497 | - | 7e-46 | 70.31% (128) | low molecular weight phosphotyrosine protein phosphatase |
| M. smegmatis MC2 155 | MSMEG_1171 | - | 4e-25 | 42.11% (133) | low molecular weight phosphotyrosine protein phosphatase |
| M. thermoresistible (build 8) | TH_1049 | arsC | 1e-26 | 43.45% (145) | PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSC |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3220 | - | 2e-36 | 55.07% (138) | protein tyrosine phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4864|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1497|M.avium_104 --------------------------------------------------
Mflv_1656|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3220|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
Rv2643|M.tuberculosis_H37Rv MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
MMAR_2055|M.marinum_M MTGTVDHQPAPAVVGKLSTLDRFLPVWIGLAMAAGLLLGRWIPGLNTALE
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
TH_1049|M.thermoresistible__bu --------------------------------------------------
MAB_4864|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1497|M.avium_104 --------------------------------------------------
Mflv_1656|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3220|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
Rv2643|M.tuberculosis_H37Rv GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
MMAR_2055|M.marinum_M KVQVDGISLPIALGLLIMMYPVLAKVRYDRLDSVTGDRKLLISSLLLNWV
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
TH_1049|M.thermoresistible__bu --------------------------------------------------
MAB_4864|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1497|M.avium_104 --------------------------------------------------
Mflv_1656|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3220|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
Rv2643|M.tuberculosis_H37Rv LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MMAR_2055|M.marinum_M AGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLARGDREAA
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
TH_1049|M.thermoresistible__bu --------------------------------------------------
MAB_4864|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1497|M.avium_104 --------------------------------------------------
Mflv_1656|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3220|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
Rv2643|M.tuberculosis_H37Rv AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
MMAR_2055|M.marinum_M AVLVALNSIFQVAMFAVLGWFYLSVLPGWLHLTQTTISTSPWQIAKSVLI
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
TH_1049|M.thermoresistible__bu --------------------------------------------------
MAB_4864|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1497|M.avium_104 --------------------------------------------------
Mflv_1656|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3220|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
Rv2643|M.tuberculosis_H37Rv FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
MMAR_2055|M.marinum_M FLGIPLLAGYLSRRLGERAKGRGWYESRFLPKVGPWALYGLLFTIVILFA
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
TH_1049|M.thermoresistible__bu --------------------------------------------------
MAB_4864|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1497|M.avium_104 --------------------------------------------------
Mflv_1656|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3220|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
Rv2643|M.tuberculosis_H37Rv LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
MMAR_2055|M.marinum_M LQGDQITNRPQDVARIALPLLVYFAVMWGGGYLLGAALHLGYQRTTTMAF
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
TH_1049|M.thermoresistible__bu --------------------------------------------------
MAB_4864|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1497|M.avium_104 --------------------------------------------------
Mflv_1656|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3220|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2676|M.bovis_AF2122/97 TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
Rv2643|M.tuberculosis_H37Rv TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
MMAR_2055|M.marinum_M TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
TH_1049|M.thermoresistible__bu --------------------------------------------------
MAB_4864|M.abscessus_ATCC_1997 -----MTNDLTSGRIPAVLFVCVKNGGKSQMAAALMRQIAGDSVEVHSAG
MAV_1497|M.avium_104 -----------------MLFVCVKNAGKSQMAAGLMRKVAGDTVDVFSAG
Mflv_1656|M.gilvum_PYR-GCK -----MTPK------PSVLFVCVKNGGKSQMAAGLMRRLAGEEIDVYSAG
Mvan_3220|M.vanbaalenii_PYR-1 -----MSRT-----APRVLFVCVSNAGKSVMAQGLMRHLAPTQITALSAG
Mb2676|M.bovis_AF2122/97 NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
Rv2643|M.tuberculosis_H37Rv NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
MMAR_2055|M.marinum_M NRYYGPHRRKHDMIKPSVLFVCVHNAGRSQMAAGWLRHLAGDRIEVRSAG
MSMEG_1171|M.smegmatis_MC2_155 ------------MTGPTVLFLCTHNAGRSQMALGYFTHLAGDGAVAWSGG
TH_1049|M.thermoresistible__bu ----MTSDSATDNPTPSVLFVCVHNAGRSQMAAGFLTALAGGRIEVRSAG
:**:*. *.*:* ** . : :* . *.*
MAB_4864|M.abscessus_ATCC_1997 TAPGSAVNALSAESLHEVGASTEGEYPKTIDPDLLARIDQVITLGREAKV
MAV_1497|M.avium_104 TRPGDALNALSAESLAEVGVDISAEHPKPIDRDVLAHVDRVVVLGREAQV
Mflv_1656|M.gilvum_PYR-GCK TAPGAAVNALSAESLREVGIDISGEKPKQVDPQRVRQVDMVVTLGREAQV
Mvan_3220|M.vanbaalenii_PYR-1 TNAKGAVNDVSAQALAELGIDVSAHRPTQLTDEMIDDADLVVVVGTQAHV
Mb2676|M.bovis_AF2122/97 TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
Rv2643|M.tuberculosis_H37Rv TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
MMAR_2055|M.marinum_M TEPADRINPVAVAAMAELGIDITANTPEVLTGAWVQTSDVVITMGCGDAC
MSMEG_1171|M.smegmatis_MC2_155 SEPAAEINPVAVAAMAEVGIDITGEYPKPWTDEIVRVADVVITMGCGDTC
TH_1049|M.thermoresistible__bu SAPADQLNPAAVEAMAEVGIDISTHQPKVLTTDAVQASDVVITMGCGDTC
: . :* :. :: *:* . . * : * *:.:*
MAB_4864|M.abscessus_ATCC_1997 EVPEGVTLDNWDTDEPSERGIEGIERMRLVRDDIAGRVQQLHRQL-----
MAV_1497|M.avium_104 EPTEGVTVETWVTDEPSERGIDGIERMRLVRDDIARRVETLHRSL-----
Mflv_1656|M.gilvum_PYR-GCK EPVPGTRFENWDTDEPAERGIDGIERMRLVRDDIATRVGRLAEQL-----
Mvan_3220|M.vanbaalenii_PYR-1 DPVGDTPVEVWDTDEPSLRGIDGMERMRLIRDDIAGRVAALADRL-----
Mb2676|M.bovis_AF2122/97 PYFPGASYRNWKLPDPAGQPLD---VVRMIRDDIADRVQALIAEL-----
Rv2643|M.tuberculosis_H37Rv PYFPGVSYRNWKLPDPAGQPLD---VVRMIRDDIADRVQALIAEL-----
MMAR_2055|M.marinum_M PYFPGVSYRDWTLADPAGQPLD---VVRPIRDDIGERVRALIAEL-----
MSMEG_1171|M.smegmatis_MC2_155 PVYPGKRYENWELPDPAGQALD---AVRPIRDDIEHRVRRLLADL-----
TH_1049|M.thermoresistible__bu PIFPGRSYRDWVLDDPAGKDLD---DVRRIRDDIKARVEDLIAELDPPPD
. * :*: : :: :* :**** ** * *
MAB_4864|M.abscessus_ATCC_1997 -TATAN------------
MAV_1497|M.avium_104 -LGD--------------
Mflv_1656|M.gilvum_PYR-GCK -RTAARLHPEENAR----
Mvan_3220|M.vanbaalenii_PYR-1 -TRQHPPV----------
Mb2676|M.bovis_AF2122/97 LATAKTR-----------
Rv2643|M.tuberculosis_H37Rv LATAKTR-----------
MMAR_2055|M.marinum_M LNEHPDTAQICRG-----
MSMEG_1171|M.smegmatis_MC2_155 GVATIR------------
TH_1049|M.thermoresistible__bu LNARDRPVPATRAGTTTR