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ADRKPAVLFLCTHNAGRSQMAMGFFRHLAADRATVYSAGSEPAAHVNPAAVAAMAEKGIDISGQQPRRWS TDIVEAVDVVVTMGCGDECPYIPGKRYENWELADPAGRGVDDVRPIRDEIEQHVRLLLSELGVDVGAVST VPEPLHQVIRRLQQGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3468 | - | - | 100% (157) | protein tyrosine phosphatase |
| M. gilvum PYR-GCK | Mflv_1659 | - | 1e-50 | 69.40% (134) | protein tyrosine phosphatase |
| M. gilvum PYR-GCK | Mflv_1656 | - | 3e-27 | 44.27% (131) | protein tyrosine phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2676 | arsC | 8e-41 | 60.16% (128) | arsenic-transport integral membrane protein ArsC |
| M. tuberculosis H37Rv | Rv2643 | arsC | 1e-40 | 60.16% (128) | arsenic-transport integral membrane protein ArsC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2568 | - | 2e-48 | 66.92% (130) | putative arsenate reductase or tyrosine phosphatase |
| M. marinum M | MMAR_2055 | arsC | 5e-42 | 61.72% (128) | arsenic-transport integral membrane protein ArsC |
| M. avium 104 | MAV_1496 | - | 2e-51 | 67.16% (134) | low molecular weight phosphotyrosine protein phosphatase |
| M. smegmatis MC2 155 | MSMEG_1171 | - | 5e-51 | 68.99% (129) | low molecular weight phosphotyrosine protein phosphatase |
| M. thermoresistible (build 8) | TH_1049 | arsC | 2e-40 | 61.42% (127) | PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSC |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3221 | - | 4e-51 | 67.16% (134) | protein tyrosine phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MAB_2568|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3468|M.gilvum_PYR-GCK --------------------------------------------------
Mb2676|M.bovis_AF2122/97 MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
Rv2643|M.tuberculosis_H37Rv MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
MMAR_2055|M.marinum_M MTGTVDHQPAPAVVGKLSTLDRFLPVWIGLAMAAGLLLGRWIPGLNTALE
TH_1049|M.thermoresistible__bu --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MAB_2568|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3468|M.gilvum_PYR-GCK --------------------------------------------------
Mb2676|M.bovis_AF2122/97 GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
Rv2643|M.tuberculosis_H37Rv GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
MMAR_2055|M.marinum_M KVQVDGISLPIALGLLIMMYPVLAKVRYDRLDSVTGDRKLLISSLLLNWV
TH_1049|M.thermoresistible__bu --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MAB_2568|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3468|M.gilvum_PYR-GCK --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
Rv2643|M.tuberculosis_H37Rv LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MMAR_2055|M.marinum_M AGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLARGDREAA
TH_1049|M.thermoresistible__bu --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MAB_2568|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3468|M.gilvum_PYR-GCK --------------------------------------------------
Mb2676|M.bovis_AF2122/97 AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
Rv2643|M.tuberculosis_H37Rv AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
MMAR_2055|M.marinum_M AVLVALNSIFQVAMFAVLGWFYLSVLPGWLHLTQTTISTSPWQIAKSVLI
TH_1049|M.thermoresistible__bu --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1496|M.avium_104 --------------------------------------------------
MAB_2568|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3468|M.gilvum_PYR-GCK --------------------------------------------------
Mb2676|M.bovis_AF2122/97 FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
Rv2643|M.tuberculosis_H37Rv FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
MMAR_2055|M.marinum_M FLGIPLLAGYLSRRLGERAKGRGWYESRFLPKVGPWALYGLLFTIVILFA
TH_1049|M.thermoresistible__bu --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3221|M.vanbaalenii_PYR-1 --------------------------MTDTPV--THQLRRDLPIDQQLAL
MAV_1496|M.avium_104 --------------------------MTDSPASLAAHVRRDISIDQQLAL
MAB_2568|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3468|M.gilvum_PYR-GCK --------------------------------------------------
Mb2676|M.bovis_AF2122/97 LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
Rv2643|M.tuberculosis_H37Rv LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
MMAR_2055|M.marinum_M LQGDQITNRPQDVARIALPLLVYFAVMWGGGYLLGAALHLGYQRTTTMAF
TH_1049|M.thermoresistible__bu --------------------------------------------------
MSMEG_1171|M.smegmatis_MC2_155 ------------------------------MTG-----------------
Mvan_3221|M.vanbaalenii_PYR-1 KAAANQLQTEFGDTIGAETIERFLHSSYAHFAGRAKVPNFLPLLAERYAR
MAV_1496|M.avium_104 RTASTRLHDDFAEHFGVETIERFLHSSYDQFAGRATVPNFLPLLAERWAR
MAB_2568|M.abscessus_ATCC_1997 ------------------------------MTD-----------------
Mflv_3468|M.gilvum_PYR-GCK ------------------------------MADR----------------
Mb2676|M.bovis_AF2122/97 TAASN--NFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLA
Rv2643|M.tuberculosis_H37Rv TAASN--NFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLA
MMAR_2055|M.marinum_M TAAGN--NFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLA
TH_1049|M.thermoresistible__bu ----------------MTSDSAT---------------------------
MSMEG_1171|M.smegmatis_MC2_155 -----------------PTVLFLCTHNAGRSQMALGYFTHLAGDGAVAWS
Mvan_3221|M.vanbaalenii_PYR-1 QQLSALARVEAKIPDGKPTVLFLCTHNAGRSQMALGFLTHLAGDKVVGWS
MAV_1496|M.avium_104 QRLTALARVEGKVTDTKPTVLFLCTHNAGRSQMALGYFNHLAGDQGVAWS
MAB_2568|M.abscessus_ATCC_1997 ----------------KPTVLFLCTHNAGRSQMALGYFTNLARGNAVGMS
Mflv_3468|M.gilvum_PYR-GCK ----------------KPAVLFLCTHNAGRSQMAMGFFRHLAADRATVYS
Mb2676|M.bovis_AF2122/97 LRNRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRS
Rv2643|M.tuberculosis_H37Rv LRNRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRS
MMAR_2055|M.marinum_M LRNRYYGPHRRKHDMIKPSVLFVCVHNAGRSQMAAGWLRHLAGDRIEVRS
TH_1049|M.thermoresistible__bu -------------DNPTPSVLFVCVHNAGRSQMAAGFLTALAGGRIEVRS
*:***:*.********* * : ** . *
MSMEG_1171|M.smegmatis_MC2_155 GGSEPAAEINPVAVAAMAEVGIDITGEYPKPWTDEIVRVADVVITMGCGD
Mvan_3221|M.vanbaalenii_PYR-1 GGSEPGHEINPAAVAAMAEVGIDITGEFPKPWTEEIVRAADVVVTMGCGD
MAV_1496|M.avium_104 GGSEPGNEINPAAVQAMAEVGIDITREFPKPWTDEIVQASDVVVTMGCGD
MAB_2568|M.abscessus_ATCC_1997 GGSEPADQINPAAIAVMHEVGIDITTEYPKPWSVETVQAADVVVTMGCDD
Mflv_3468|M.gilvum_PYR-GCK AGSEPAAHVNPAAVAAMAEKGIDISGQQPRRWSTDIVEAVDVVVTMGCGD
Mb2676|M.bovis_AF2122/97 AGTEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGD
Rv2643|M.tuberculosis_H37Rv AGTEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGD
MMAR_2055|M.marinum_M AGTEPADRINPVAVAAMAELGIDITANTPEVLTGAWVQTSDVVITMGCGD
TH_1049|M.thermoresistible__bu AGSAPADQLNPAAVEAMAEVGIDISTHQPKVLTTDAVQASDVVITMGCGD
.*: *. .:**.*: .* * ****: . * : *. ***:****.*
MSMEG_1171|M.smegmatis_MC2_155 TCPVYPGKRYENWELPDPAGQALDAVRPIRDDIEHRVRRLLADLGV-ATI
Mvan_3221|M.vanbaalenii_PYR-1 ACPVFPGKRYENWELTDPAGQGLEAVRPIRDDVEERVRRLLADLQVPVAV
MAV_1496|M.avium_104 ACPFFPGKRYENWDLTDPAGQGVDVVRPIRDEIESRVRRLLAELHITPVS
MAB_2568|M.abscessus_ATCC_1997 SCPYFPGKRYENWELADPAGQSVEAIRPIRDDIEQRVRELLISLGVAGVV
Mflv_3468|M.gilvum_PYR-GCK ECPYIPGKRYENWELADPAGRGVDDVRPIRDEIEQHVRLLLSELGVDVGA
Mb2676|M.bovis_AF2122/97 ACPYFPGASYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAEL-----L
Rv2643|M.tuberculosis_H37Rv ACPYFPGVSYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAEL-----L
MMAR_2055|M.marinum_M ACPYFPGVSYRDWTLADPAGQPLDVVRPIRDDIGERVRALIAEL-----L
TH_1049|M.thermoresistible__bu TCPIFPGRSYRDWVLDDPAGKDLDDVRRIRDDIKARVEDLIAELDPPPDL
** ** *.:* * ****: :: :* ***:: :*. *: .*
MSMEG_1171|M.smegmatis_MC2_155 R------------------
Mvan_3221|M.vanbaalenii_PYR-1 R------------------
MAV_1496|M.avium_104 -------------------
MAB_2568|M.abscessus_ATCC_1997 EP-----------------
Mflv_3468|M.gilvum_PYR-GCK VSTVPEPLHQVIRRLQQGS
Mb2676|M.bovis_AF2122/97 ATAKTR-------------
Rv2643|M.tuberculosis_H37Rv ATAKTR-------------
MMAR_2055|M.marinum_M NEHPDTAQICRG-------
TH_1049|M.thermoresistible__bu NARDRPVPATRAGTTTR--