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VLVELSPSGGLFQFAFELGSALAACGQQVELWTGPRPELESSQPGFTVRPVLPTWHPGDTGVHSRAFRLA RRGIRAVQLIFAWMVLSVRLLVARPRAVLWSQWRFTFEPMFVVALSALLRSATLGLIAHEPVPRSDAKDT STAKGGEMLTRTFRAAWQRLDVVFVLGPRTRDLAVSYWQPRCPVHVIPHGAEPGVRGGTAVRPVADTGPV VLFFGVWAKYKGIEVLLEAFDRVRAEMPESQLVLAGDVGADVDLASVLDRAGRIGNVDARPGYVAIEDVP ALFDAARVVAVPYIRATQSGVAHLAFTFGRPVVASNIGDLPEVIQDGVTGLLVDPEDVGGLTAAILTLLR DVSFAARLGAAGERSVSDAWSVAAARVRDALAAAETGAGQGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1498 | - | - | 100% (392) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_2961 | - | 2e-15 | 30.51% (236) | glycosyl transferase, group 1 |
| M. gilvum PYR-GCK | Mflv_4262 | - | 4e-13 | 27.41% (394) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3058 | - | 2e-13 | 31.43% (210) | transferase |
| M. tuberculosis H37Rv | Rv3032 | - | 2e-13 | 31.43% (210) | transferase |
| M. leprae Br4923 | MLBr_00886 | - | 2e-14 | 28.51% (242) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_1976 | - | 2e-15 | 28.74% (247) | hypothetical protein MAB_1976 |
| M. marinum M | MMAR_3232 | - | 7e-14 | 27.16% (243) | glycosyltransferase |
| M. avium 104 | MAV_4082 | - | 6e-13 | 31.56% (225) | transferase |
| M. smegmatis MC2 155 | MSMEG_6484 | - | 1e-15 | 26.09% (414) | glycosyl transferase |
| M. thermoresistible (build 8) | TH_1111 | - | 2e-14 | 30.36% (224) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1919 | - | 4e-13 | 31.61% (193) | transferase |
| M. vanbaalenii PYR-1 | Mvan_5248 | - | 0.0 | 84.72% (386) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00886|M.leprae_Br4923 --------MSRVLLVTNDFPPRRGGIQSYLGEFVDRLINIGSHDVMVYA-
MMAR_3232|M.marinum_M --------MSRVLLVTNDFPPRRGGIQSYLSEFVGRLVEAGSHSITVYA-
TH_1111|M.thermoresistible__bu -----VTGVSRVLLVTNDFPPRPGGIQSYLHELVLRLVRTQSHVVTVYA-
MAB_1976|M.abscessus_ATCC_1997 MTFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLA--GSHEVTVYA-
Mb3058|M.bovis_AF2122/97 ---------MRILMVSWEYPPVVIGGLGRHVHHLSTALAAAGHDVVVLS-
Rv3032|M.tuberculosis_H37Rv ---------MRILMVSWEYPPVVIGGLGRHVHHLSTALAAAGHDVVVLS-
MUL_1919|M.ulcerans_Agy99 ---------MKILMVSWEYPPVVIGGLGRHVHHLATALVAAGHEVVVLS-
Mflv_1498|M.gilvum_PYR-GCK --------------MLVELSP-SGGLFQFAFELGSALAACGQQVELWTG-
Mvan_5248|M.vanbaalenii_PYR-1 --------------MLVELSP-SGGLFQFAFELGSALAARGERVELWTG-
MAV_4082|M.avium_104 ---MRIAMISEHASPLAHLGGVDAGGQNVHVAELSCALARRGHDVVVYT-
MSMEG_6484|M.smegmatis_MC2_155 ----------MRIALLSYRSKTHCGGQGVYVRHLSSGLAELGHDVEVFSG
* :
MLBr_00886|M.leprae_Br4923 -PQWTGADT---------------FDNAAHDGGYQVVRHPGTLMLPGPAV
MMAR_3232|M.marinum_M -PQWKGAQG---------------YDDVARAAGYRVVRHPSTLMLPVPTV
TH_1111|M.thermoresistible__bu -PRWRGSDD---------------FDAEAARTGYRVVRHPGTLMLPEPSV
MAB_1976|M.abscessus_ATCC_1997 -PRWKGCER---------------YDAAAE---YQVVRHPTSLMLPGPGV
Mb3058|M.bovis_AF2122/97 -RCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHA
Rv3032|M.tuberculosis_H37Rv -RCPSGTDPSTHPSSDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHA
MUL_1919|M.ulcerans_Agy99 -RRPSGTDPSTHPSSDLISEGVRVIAAAQDPHEFSFGSDMMAWTLAMGHA
Mflv_1498|M.gilvum_PYR-GCK -PRPELESSQPGFTVRPVLPTWHPGDTGVHSRAFRLARRGIRAVQLIFAW
Mvan_5248|M.vanbaalenii_PYR-1 -PRPELASSQPGFTVRPVLPTWHPGDTGVHSRAFRLARRGFRAGQLIFAW
MAV_4082|M.avium_104 -RRDDPRLP----------------DSVETPHGYSVVHVPAGPARVLPKD
MSMEG_6484|M.smegmatis_MC2_155 QPYPEGLDPRVTLTKVPSLDLYREPDPFRVPHPREIRDGIDALELLTMWS
.
MLBr_00886|M.leprae_Br4923 D---------ARMRRLIVDHGIDTVWFG------------SAAPLALLAP
MMAR_3232|M.marinum_M D---------SRMRRLIAQHDIDTVWFG------------AAAPLALLAP
TH_1111|M.thermoresistible__bu A---------RRMRRLIRDEGIDTVWFG------------AAAPLALLAG
MAB_1976|M.abscessus_ATCC_1997 R---------RRMVDLIRAQHADVVWFG------------AAAPLALLSS
Mb3058|M.bovis_AF2122/97 M---------IRAGLRLKKLGTDRSWRPD---VVHAHDWLVAHPAIALAQ
Rv3032|M.tuberculosis_H37Rv M---------IRAGLRLKKLGTDRSWRPD---VVHAHDWLVAHPAIALAQ
MUL_1919|M.ulcerans_Agy99 M---------VRAGLTLSGPGAEQPWQPD---IVHAHDWLVAHPAIALAD
Mflv_1498|M.gilvum_PYR-GCK M---------VLSVRLLVARPRAVLWSQW---RFTFEPMFVVALSALLRS
Mvan_5248|M.vanbaalenii_PYR-1 T---------VLSVRLLAARPHAVLWSQW---RFAFEPMFVVAVSTLLRS
MAV_4082|M.avium_104 E---------LLQYMYGFAQFLRQQWCSDGPDVAHAHFWMSGVATQQAAR
MSMEG_6484|M.smegmatis_MC2_155 AGFPEPRTFTMRAARILAARRDEFDVVHDNQSLGTGLLKIEKLGLPVVAT
MLBr_00886|M.leprae_Br4923 CARKAGATRVLASTHGHEVGWSMLPVAR---SVLRRIGDVTDVVTFVSRY
MMAR_3232|M.marinum_M RARQAGATRVLASTHGHEVGWSMLPVAR---SVLRRIGDTTDIVTFVSRY
TH_1111|M.thermoresistible__bu TARAAGARRVLASTHGHEVGWSMLPVAR---HALRIIGDNTDVLTYVSRY
MAB_1976|M.abscessus_ATCC_1997 AAKAAGAAVTAASTHGHEVGWSMLPVAR---SALRQIGESTDVITYVSRY
Mb3058|M.bovis_AF2122/97 FYDVPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSAS
Rv3032|M.tuberculosis_H37Rv FYDVPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSAS
MUL_1919|M.ulcerans_Agy99 YYDVPMVSTIHATEAGRHSGWVSGDLSRQVHAVESWLVRESDSLITCSGS
Mflv_1498|M.gilvum_PYR-GCK ATLGLIAHEPVPRSDAKDTSTAKGGEMLT--RTFRAAWQRLDVVFVLGPR
Mvan_5248|M.vanbaalenii_PYR-1 SILGLIAHEPVPRSDAKDTSTAKAGALLT--RAFRAAWRRLDVAFVLGPR
MAV_4082|M.avium_104 AHSIPTVQTFHALGLTKRLHQGSDDTSPDCRIDVEARVAREADWVAATST
MSMEG_6484|M.smegmatis_MC2_155 VHHPITRDKVVDVAAAKWWRKPLVRRWYGFAEMQKKVARQIPELLTVSSS
:
MLBr_00886|M.leprae_Br4923 TRSRVTAAFGP-RAALEYLPPGVDADRFRPDPASRAELRNRYRLGERPTV
MMAR_3232|M.marinum_M TRSRFAPAFGP-AASLEYLPPGVDTDRFRPDPAARAELRKRYQLGERPTV
TH_1111|M.thermoresistible__bu TRRRFASAFGP-RAGLEHVPPGVDIDRFAPDPVARTALRTRYRLGERPVV
MAB_1976|M.abscessus_ATCC_1997 TRGRFASAFGP-RAALEYLPSGVDTNRFCPDPAAREELRERYGLGDRPTI
Mb3058|M.bovis_AF2122/97 MNDEITELFGPGLAEITVIRNGIDAARWP--------FAARRPRTGPAEL
Rv3032|M.tuberculosis_H37Rv MNDEITELFGPGLAEITVIRNGIDAARWP--------FAARRPRTGPAEL
MUL_1919|M.ulcerans_Agy99 MSDEITELFGPGLAETAVIRNGIDVARWP--------FAVRKPRTGPPEL
Mflv_1498|M.gilvum_PYR-GCK TRDLAVSYWQP-RCPVHVIPHGAEPGVRG-------GTAVRPVADTGPVV
Mvan_5248|M.vanbaalenii_PYR-1 TRDLAVTHWQP-RCPVYVIPHGAEPGVRG-------GRSVRPVADTEPVV
MAV_4082|M.avium_104 DEVFELVRMGRARSRTSVVPCGVDLDAFTPD-------GPVAARGARPRI
MSMEG_6484|M.smegmatis_MC2_155 SAADIAADFGVTSDQLHIVPLGVNTELFKP----------AEQRVSGRII
: * : :
MLBr_00886|M.leprae_Br4923 VCLARLVPRKGQDMLIRALPSIRQRADGAALMIVGG--------GPYLGT
MMAR_3232|M.marinum_M VCVSRLVPRKGQDTLIKALPAIRRRVDGAALVIVGG--------GPYLET
TH_1111|M.thermoresistible__bu LCLSRLVPRKGQDMLIRALPMIRRRVGDAVLVIVGG--------GPYRTA
MAB_1976|M.abscessus_ATCC_1997 VCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGG--------GPYAEP
Mb3058|M.bovis_AF2122/97 LYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGE--------GTQQDW
Rv3032|M.tuberculosis_H37Rv LYVGRLEYEKGVHDAIAALPRLRRTHPGTTLTIAGE--------GTQQDW
MUL_1919|M.ulcerans_Agy99 LYVGRLEYEKGVHNAIAALPRIRRAHPGTTLTIAGE--------GTQQDW
Mflv_1498|M.gilvum_PYR-GCK LFFGVWAKYKGIEVLLEAFDRVRAEMPESQLVLAGDV-------GADVDL
Mvan_5248|M.vanbaalenii_PYR-1 LFFGVWAKYKGIEVLLDAFARVRAELPESQLVLAGDV-------GADIDL
MAV_4082|M.avium_104 VTVGRLVPRKGFDTIVRALP----RIPDAELVIVGGPPAAELAGDEQARR
MSMEG_6484|M.smegmatis_MC2_155 AIASADVPLKGVSHLLHAVARLRVERNLDLQLVSKLE---------PNGP
. ** : *. :
MLBr_00886|M.leprae_Br4923 LRKLAQGCGVADHVIFAGGVAAVEVPAHYTLADVFAMPCRTRGGGMDVEG
MMAR_3232|M.marinum_M LRKLARDCEVDEHVTFTGGVPGEELPTHHAMADVFAMPCRTRGSGMDVEG
TH_1111|M.thermoresistible__bu LQRLAHRYDVAAHVVFTGGIPAEELPAHHAMADVFAMPCRTRGAGLDVEG
MAB_1976|M.abscessus_ATCC_1997 LRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEG
Mb3058|M.bovis_AF2122/97 LIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPS-------HYEP
Rv3032|M.tuberculosis_H37Rv LIDQARKHRVLRATRFVGHLDHTELLALLHRADAAVLPS-------HYEP
MUL_1919|M.ulcerans_Agy99 LVEQARKHRVLKATKFLGHLEHAELLTLLHRADAAVFPS-------HYEP
Mflv_1498|M.gilvum_PYR-GCK ASVLDRAGRIGNVDARPGYVAIEDVPALFDAARVVAVPY------IRATQ
Mvan_5248|M.vanbaalenii_PYR-1 PSVLDRAGQIGNVDARPGYVAIDDVAALFDAARVVAVPY------IRATQ
MAV_4082|M.avium_104 LQRLAGELGVADRVRLLGGVTRAQMPALLRSADVVACTP-------WYEP
MSMEG_6484|M.smegmatis_MC2_155 TEKLIAELGISDIVHISSGLSDQELAGLLASAEVACIPS-------LYEG
: . : :: . . .
MLBr_00886|M.leprae_Br4923 LGIVFLEASATGVPVIAGKSGGAPEAV-QHNKTGLVVDGRSVNMVADAVT
MMAR_3232|M.marinum_M LGIVFLEASASGVPVIAGESGGAPETV-QHNKTGLVVDGNSVDKVAGAVI
TH_1111|M.thermoresistible__bu LGIVYLEASATGVPVVAGRSGGAPETV-RHGETGLVVDGRDVREIATAVG
MAB_1976|M.abscessus_ATCC_1997 LGIVFLEASACGVPVVAGNSGGAPETV-RAGETGVVVDGRSVSAITDAIV
Mb3058|M.bovis_AF2122/97 FGLVALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCAPRDVAGLAAAVR
Rv3032|M.tuberculosis_H37Rv FGLVALEAAAAGTPLVTSNIGGLGEAV-INGQTGVSCAPRDVAGLAAAVR
MUL_1919|M.ulcerans_Agy99 FGLVALEAAAAGTPLVTSNIGGLGEAV-IDGVTGVSCPPRDVAALAAAVC
Mflv_1498|M.gilvum_PYR-GCK SGVAHLAFTFG-RPVVASNIGDLPEVI-QDGVTGLLVDPEDVGGLTAAIL
Mvan_5248|M.vanbaalenii_PYR-1 SGVAHLAFTFG-RPVVSSAVGDLPEVI-EDRVTGLLVEPDDADGLAAALV
MAV_4082|M.avium_104 FGIVPLEAMACGVPVVATAVGGIRDTV-VDGATGRLVPPKDPDALGEAVA
MSMEG_6484|M.smegmatis_MC2_155 FSLPAVEAMASGTPIVASRAGALPEVVGTDGSCARLVRPADVDELTAVLG
.: : *::: * :.: . . : .:
MLBr_00886|M.leprae_Br4923 ELLTDRDRAAAMGAAGRHWVTAEWRWDTLAARLADLLCGNDSR-------
MMAR_3232|M.marinum_M EVLADRDRAARMGDAGRQWVTSQWRWDTLAARLAELLRGDDTGR------
TH_1111|M.thermoresistible__bu DLLSDPDRAAAMGAAGRQWVVQQWQWQTQADRLARLLQV-----------
MAB_1976|M.abscessus_ATCC_1997 QILVDPARAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA---------
Mb3058|M.bovis_AF2122/97 SVLDDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPR
Rv3032|M.tuberculosis_H37Rv SVLDDPAAAQRRARAARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPR
MUL_1919|M.ulcerans_Agy99 GVLDDPAAAQQRARAARERLNSNFDWQTVAEQTAQVYLAAKRGERQPLPR
Mflv_1498|M.gilvum_PYR-GCK TLLRDVSFAARLGAAGERSVSD--AWSVAAARVRDALAAAETG-AGQGH-
Mvan_5248|M.vanbaalenii_PYR-1 ELLRNPSLAATLGAAGEQRVND--AWTTAAARVCDALAEAATVRSRKGD-
MAV_4082|M.avium_104 ALLRDGRRGRTLGEAGRERARARYSWDRVAADTERIYERLSPARRGVGTP
MSMEG_6484|M.smegmatis_MC2_155 ELLDSPAERRRLGAAGRQRALDVFSWESVAAQTVAVYERAQNRMGVKAC-
:* . . *.. * *
MLBr_00886|M.leprae_Br4923 -----------
MMAR_3232|M.marinum_M -----------
TH_1111|M.thermoresistible__bu -----------
MAB_1976|M.abscessus_ATCC_1997 -----------
Mb3058|M.bovis_AF2122/97 LPIVEHALPDR
Rv3032|M.tuberculosis_H37Rv LPIVEHALPDR
MUL_1919|M.ulcerans_Agy99 LPIVEHALPDR
Mflv_1498|M.gilvum_PYR-GCK -----------
Mvan_5248|M.vanbaalenii_PYR-1 -----------
MAV_4082|M.avium_104 STRSG------
MSMEG_6484|M.smegmatis_MC2_155 -----------