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M. gilvum PYR-GCK Mflv_2961 (-)

annotation: glycosyl transferase, group 1
coordinates: 3132051 - 3133199
length: 382

VGGLVKRILLVTNDFPPRRGGIQSYLEALVGHLVASGDHTLTVYAPKWKGAPDYDAVAAATGYEVVRHPG
TLMLPEPTVVLRMRKIIAERGIDTVWFGAAAPLALMAPLARAAGARRVIASTHGHEVGWSMLPLARNALR
RIGNDTDVVTYISAYTRGRFASAFGPDAALEHVPPGVDTDRFVPDEVARAEMRARYRLGNRPVVACVSRL
VPRKGQDMLIRALPAIRQRAPGAALVIVGGGPYRTSLHRLAHDFGVADHVVFTDGVPGEELPAHHAMADV
FAMPCRTRGSGLDVEGLGIVYLEASSTGVPVVAGRSGGAPETVRDGETGLVVDGWDVGAIAASVGELLAD
PARAAAMGAAGRQWAVDNWRWSLQAERLARLL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2961--100% (382)glycosyl transferase, group 1
M. gilvum PYR-GCKMflv_1500-2e-2128.49% (365) glycosyl transferase, group 1
M. gilvum PYR-GCKMflv_4262-9e-2127.82% (399) glycosyl transferase, group 1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2211c-1e-15670.63% (378) hypothetical protein Mb2211c
M. tuberculosis H37RvRv2188c-1e-15670.63% (378) hypothetical protein Rv2188c
M. leprae Br4923MLBr_00886-1e-15068.25% (378) putative glycosyl transferase
M. abscessus ATCC 19977MAB_1976-1e-14969.03% (381) hypothetical protein MAB_1976
M. marinum MMMAR_3232-1e-15871.96% (378) glycosyltransferase
M. avium 104MAV_2306-1e-15371.69% (378) glycosyl transferase, group 1
M. smegmatis MC2 155MSMEG_4253-1e-16876.27% (375) glycosyl transferase, group 1 family protein
M. thermoresistible (build 8)TH_1111-1e-17076.98% (378) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_3543-1e-15871.69% (378) glycosyltransferase
M. vanbaalenii PYR-1Mvan_3550-0.090.74% (378) glycosyl transferase, group 1

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2961|M.gilvum_PYR-GCK          ----MGGLVKRILLVTNDFPPRRGGIQSYLEALVGHLVASGDHTLTVYAP
Mvan_3550|M.vanbaalenii_PYR-1       --------MKRILLVTNDYPPRRGGIQAYLEALVEHLVASGEHSLTVYAP
MSMEG_4253|M.smegmatis_MC2_155      -----------MLLVTNDFPPRRGGIQSYLEAFVGELVRT--HELTVYAP
TH_1111|M.thermoresistible__bu      -----VTGVSRVLLVTNDFPPRPGGIQSYLHELVLRLVRTQSHVVTVYAP
Mb2211c|M.bovis_AF2122/97           --------MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAP
Rv2188c|M.tuberculosis_H37Rv        --------MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAP
MMAR_3232|M.marinum_M               --------MSRVLLVTNDFPPRRGGIQSYLSEFVGRLVEAGSHSITVYAP
MUL_3543|M.ulcerans_Agy99           --------MSRVLLVTNDFPPRRGGIQSYLSESVGRLVEAGSHSITVYAP
MLBr_00886|M.leprae_Br4923          --------MSRVLLVTNDFPPRRGGIQSYLGEFVDRLINIGSHDVMVYAP
MAV_2306|M.avium_104                --------MSRVLLVTNDFPPRPGGIHSYLGEFVGRLAAAGSHELTVYAP
MAB_1976|M.abscessus_ATCC_1997      MTFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLAG--SHEVTVYAP
                                               :******:*** ***::**   * .*     * : ****

Mflv_2961|M.gilvum_PYR-GCK          KWKGAPDYDAVAAATGYEVVRHPGTLMLPEPTVVLRMRKIIAERGIDTVW
Mvan_3550|M.vanbaalenii_PYR-1       KWKGAEDYDSVAAATGYEVVRHPGTLMVPEPTVALRMRRLIRERGIDTVW
MSMEG_4253|M.smegmatis_MC2_155      KWKGAEEYDEKAARSGYRVVRHPTTLMLPEPTVASRMKRLIGEHDIETVW
TH_1111|M.thermoresistible__bu      RWRGSDDFDAEAARTGYRVVRHPGTLMLPEPSVARRMRRLIRDEGIDTVW
Mb2211c|M.bovis_AF2122/97           QWKGADAFDDAARAAGYRVVRHPSTVMLPGPTVDVRMRRLIAEHDIETVW
Rv2188c|M.tuberculosis_H37Rv        QWKGADAFDDAARAAGYRVVRHPSTVMLPGPTVDVRMRRLIAEHDIETVW
MMAR_3232|M.marinum_M               QWKGAQGYDDVARAAGYRVVRHPSTLMLPVPTVDSRMRRLIAQHDIDTVW
MUL_3543|M.ulcerans_Agy99           QWKGAQGYDDVARAAGYRVVRHPSTLMLPVPTVDSRMRRLIAQHDIDTVW
MLBr_00886|M.leprae_Br4923          QWTGADTFDNAAHDGGYQVVRHPGTLMLPGPAVDARMRRLIVDHGIDTVW
MAV_2306|M.avium_104                DWKGAQAHDEAV---GYRVVRHPGTLMLPGPAVDARMRRLIAEHVIDTVW
MAB_1976|M.abscessus_ATCC_1997      RWKGCERYDAAA---EYQVVRHPTSLMLPGPGVRRRMVDLIRAQHADVVW
                                     * *.  .*  .    *.***** ::*:* * *  **  :*  .  :.**

Mflv_2961|M.gilvum_PYR-GCK          FGAAAPLALMAPLARAAGARRVIASTHGHEVGWSMLPLARNALRRIGNDT
Mvan_3550|M.vanbaalenii_PYR-1       FGAAAPLALLAPLARAAGARRVIASTHGHEVGWSMLPLARTALRRIGNDT
MSMEG_4253|M.smegmatis_MC2_155      FGAAAPLALLGPLARRAGARRIVASTHGHEVGWSMLPVARTALRRIGNDA
TH_1111|M.thermoresistible__bu      FGAAAPLALLAGTARAAGARRVLASTHGHEVGWSMLPVARHALRIIGDNT
Mb2211c|M.bovis_AF2122/97           FGAAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGT
Rv2188c|M.tuberculosis_H37Rv        FGAAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGT
MMAR_3232|M.marinum_M               FGAAAPLALLAPRARQAGATRVLASTHGHEVGWSMLPVARSVLRRIGDTT
MUL_3543|M.ulcerans_Agy99           FGAAAPLALLAPRARQAGATRVLASTHGHEVGWSMLPVAGSVLRRIGDTT
MLBr_00886|M.leprae_Br4923          FGSAAPLALLAPCARKAGATRVLASTHGHEVGWSMLPVARSVLRRIGDVT
MAV_2306|M.avium_104                FGAAAPLALLAQRARAAGARRVLASTHGHEVGWSMLPVARSVLRRIGEQT
MAB_1976|M.abscessus_ATCC_1997      FGAAAPLALLSSAAKAAGAAVTAASTHGHEVGWSMLPVARSALRQIGEST
                                    **:******:.  *: ***    **************:*  .** **: :

Mflv_2961|M.gilvum_PYR-GCK          DVVTYISAYTRGRFASAFGPDAALEHVPPGVDTDRFVPDEVARAEMRARY
Mvan_3550|M.vanbaalenii_PYR-1       DVVTFISAYTRGRFASAFGPHAALEHVPPGVDTDRFVPDEVARAELRARY
MSMEG_4253|M.smegmatis_MC2_155      DVVTFVSRYTRSRFASAFGPSAALEHLPPGVDTDRFAPDPDARARMRERY
TH_1111|M.thermoresistible__bu      DVLTYVSRYTRRRFASAFGPRAGLEHVPPGVDIDRFAPDPVARTALRTRY
Mb2211c|M.bovis_AF2122/97           DVVTFVSSYTRSRFASAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
Rv2188c|M.tuberculosis_H37Rv        DVVTFVSSYTRSRFASAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
MMAR_3232|M.marinum_M               DIVTFVSRYTRSRFAPAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
MUL_3543|M.ulcerans_Agy99           DIVTFVSRYTRSRFAPAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRY
MLBr_00886|M.leprae_Br4923          DVVTFVSRYTRSRVTAAFGPRAALEYLPPGVDADRFRPDPASRAELRNRY
MAV_2306|M.avium_104                DVVTFVSRYTRSRFAPAFGPRARLEYLPSGVDTDRFRPDPAGRARLRERY
MAB_1976|M.abscessus_ATCC_1997      DVITYVSRYTRGRFASAFGPRAALEYLPSGVDTNRFCPDPAAREELRERY
                                    *::*::* *** *.:.**** * **::*.*** :** **  .*  :* **

Mflv_2961|M.gilvum_PYR-GCK          RLGNRPVVACVSRLVPRKGQDMLIRALPAIRQRAPGAALVIVGGGPYRTS
Mvan_3550|M.vanbaalenii_PYR-1       GLGERPVVVCVSRLVPRKGQDMLIRALPAIRQRVPGAALVIVGGGPYRTA
MSMEG_4253|M.smegmatis_MC2_155      GLGDRPVVVCLSRLVPRKGQDMLIRALPELRRRVPDTALAIVGGGPYLET
TH_1111|M.thermoresistible__bu      RLGERPVVLCLSRLVPRKGQDMLIRALPMIRRRVGDAVLVIVGGGPYRTA
Mb2211c|M.bovis_AF2122/97           RLGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVGGGPYLET
Rv2188c|M.tuberculosis_H37Rv        RLGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVGGGPYLET
MMAR_3232|M.marinum_M               QLGERPTVVCVSRLVPRKGQDTLIKALPAIRRRVDGAALVIVGGGPYLET
MUL_3543|M.ulcerans_Agy99           QLGERPTVVCVSRLVPRKGQDTLIKALPAIRRRVDGAALVIVGGGPYLET
MLBr_00886|M.leprae_Br4923          RLGERPTVVCLARLVPRKGQDMLIRALPSIRQRADGAALMIVGGGPYLGT
MAV_2306|M.avium_104                GLGERPTVVCVSRLVPRKGQDMLIRAMPSIVQRVDGAALVIVGGGPHLQS
MAB_1976|M.abscessus_ATCC_1997      GLGDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGGPYAEP
                                     **:**.: *::********* *: *:* : .*. .:.* ******:  .

Mflv_2961|M.gilvum_PYR-GCK          LHRLAHDFGVADHVVFTDGVPGEELPAHHAMADVFAMPCRTRGSGLDVEG
Mvan_3550|M.vanbaalenii_PYR-1       LHRLAHTFGVAEDVVFTDGVPGEELPAHHAMADVFAMPCRTRGSGLDVEG
MSMEG_4253|M.smegmatis_MC2_155      LQRMASDLGVAEHVVFTRGIPAEELPAHHAMADVFAMPCRTRGAGLDVEG
TH_1111|M.thermoresistible__bu      LQRLAHRYDVAAHVVFTGGIPAEELPAHHAMADVFAMPCRTRGAGLDVEG
Mb2211c|M.bovis_AF2122/97           LRKLAHDCGVADHVTFTGGVATDELPAHHALADVFAMPCRTRGAGMDVEG
Rv2188c|M.tuberculosis_H37Rv        LRKLAHDCGVADHVTFTGGVATDELPAHHALADVFAMPCRTRGAGMDVEG
MMAR_3232|M.marinum_M               LRKLARDCEVDEHVTFTGGVPGEELPTHHAMADVFAMPCRTRGSGMDVEG
MUL_3543|M.ulcerans_Agy99           LRKLARDCEVDEHVTFTSGVPGEELPTHHAMADVFAMPCRTRGSGMDVEG
MLBr_00886|M.leprae_Br4923          LRKLAQGCGVADHVIFAGGVAAVEVPAHYTLADVFAMPCRTRGGGMDVEG
MAV_2306|M.avium_104                LRALARDCGVAAQVTFTGGIPAAELPTHHALADVFAMPCRTRGAGLDVEG
MAB_1976|M.abscessus_ATCC_1997      LRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEG
                                    *: :*    *  .* *: *:.  *:*:*:::.***********.*:****

Mflv_2961|M.gilvum_PYR-GCK          LGIVYLEASSTGVPVVAGRSGGAPETVRDGETGLVVDGWDVGAIAASVGE
Mvan_3550|M.vanbaalenii_PYR-1       LGIVYLEASSTGVPVVAGRSGGAPETVVDGETGVVVDGWDVGAIAAAVGD
MSMEG_4253|M.smegmatis_MC2_155      LGIVYLEASACGVPVVAGRSGGAPETVLDGKTGTVVDGTDVDAITTAVGD
TH_1111|M.thermoresistible__bu      LGIVYLEASATGVPVVAGRSGGAPETVRHGETGLVVDGRDVREIATAVGD
Mb2211c|M.bovis_AF2122/97           LGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRSVDRVADAVAE
Rv2188c|M.tuberculosis_H37Rv        LGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRSVDRVADAVAE
MMAR_3232|M.marinum_M               LGIVFLEASASGVPVIAGESGGAPETVQHNKTGLVVDGNSVDKVAGAVIE
MUL_3543|M.ulcerans_Agy99           LGIVFLEASASGVPVIAGESGGAPETVQHNKTGLVVDGNSVDKVAGAVIE
MLBr_00886|M.leprae_Br4923          LGIVFLEASATGVPVIAGKSGGAPEAVQHNKTGLVVDGRSVNMVADAVTE
MAV_2306|M.avium_104                LGIVYLEASASGVPVIAGRSGGAPETVQHNKTGLVVDGRSVTEIADAVTE
MAB_1976|M.abscessus_ATCC_1997      LGIVFLEASACGVPVVAGNSGGAPETVRAGETGVVVDGRSVSAITDAIVQ
                                    ****:****: ****:**.******:*  .:** **** .*  :: :: :

Mflv_2961|M.gilvum_PYR-GCK          LLADPARAAAMGAAGRQWAVDNWRWSLQAERLARLL---------
Mvan_3550|M.vanbaalenii_PYR-1       LLADPARAAAMGAAGRQAVLDNWRWSRQAEKLARLL---------
MSMEG_4253|M.smegmatis_MC2_155      LLADPRRAAAMGVAGRHWALDNWQWRTRGARLAELLSGRREARQA
TH_1111|M.thermoresistible__bu      LLSDPDRAAAMGAAGRQWVVQQWQWQTQADRLARLLQV-------
Mb2211c|M.bovis_AF2122/97           LLIDRDRAVAMGAAGREWVTAQWRWDTLAAKLADFLRGDDAAR--
Rv2188c|M.tuberculosis_H37Rv        LLIDRDRAVAMGAAGREWVTAQWRWDTLAAKLADFLRGDDAAR--
MMAR_3232|M.marinum_M               VLADRDRAARMGDAGRQWVTSQWRWDTLAARLAELLRGDDTGR--
MUL_3543|M.ulcerans_Agy99           VLADRDRAARMGDAGRQWVTSQWRWDTLAARLAELLRGDDAGR--
MLBr_00886|M.leprae_Br4923          LLTDRDRAAAMGAAGRHWVTAEWRWDTLAARLADLLCGNDSR---
MAV_2306|M.avium_104                LLSDPDRAAAMGAAGRQWVTSQWRWDTLAARLAGLLGD-------
MAB_1976|M.abscessus_ATCC_1997      ILVDPARAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA-----
                                    :* *  **. ** ***  .  :*:*   . ::* ::