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VHTRALNGQVSHWFDGLPISRGPLPGSRDADVCIVGAGYTGLWTAYYLKRADPSLRVVVLDARFAGYGAS GRNGGWLSGLVPGDRERMARQYGRDGVVAWQRALNDAVDEVIDVAAQEGIDAGIVKGGNLEVARNRAQVR RLAAAVDAERRWQVDGVEVLTKSEAAQRIALDGVISAYYSPHCARIQPAQLVRGLADAVERLGVVIYERS PVTEITAGRAATPWGAVSAPVVLRATEGFTAGLPGLKRRWLPMNSSMIATEPVPESVWAEIGWEGRETLG DTAHGFFYAQRTVDNRIAIGGRSVPYRFGSRTDRDGRLPERTIKNLTATLHSILPQVAHVPIAHGWCGVL AVPRDWEASVDFDPATGLGWAGGYVGHGVTATNLAGRTLTDLVLTRESPLTRLPWVGHECKDWEPEPLRW IGVRGMYLAYKAADWHEARGTKRTSPIAVVANRITGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1109 | - | - | 100% (457) | FAD dependent oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3417 | - | 7e-41 | 29.49% (434) | FAD dependent oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0732 | - | 8e-08 | 34.78% (115) | FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2283 | - | 5e-39 | 28.79% (455) | putative oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6471 | - | 0.0 | 74.89% (450) | glycine/D-amino acid oxidase |
| M. thermoresistible (build 8) | TH_1303 | - | 1e-05 | 40.00% (75) | iron-sulfur binding oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5703 | - | 0.0 | 85.59% (458) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1109|M.gilvum_PYR-GCK --------------------MHTRA-LNGQVSHWFDGLPISRGPLP-GSR
Mvan_5703|M.vanbaalenii_PYR-1 --------MPTSPLGCDNLPVPTRAPVNGYVSHWFDELPFSRGPLP-GSR
MSMEG_6471|M.smegmatis_MC2_155 MAEWQEVLCGHRVISNSWQNLTVLNTVNGQISHWFDTLPTPRAPLP-GDQ
MAB_2283|M.abscessus_ATCC_1997 ------------------MNGTEIGHLAETAPIWWPGSPESAAPITDGRH
TH_1303|M.thermoresistible__bu --------------------------MTSLWLADRTNQPPPPRTLDAGDR
: * . .: * :
Mflv_1109|M.gilvum_PYR-GCK DADVCIVGAGYTGLWTAYYLKRADPSLRVVVLDARFAGYGASGRNGGWLS
Mvan_5703|M.vanbaalenii_PYR-1 DADVCIVGAGYTGLWTAYYLKRADPSLRIVVLEARFAGFGASGRNGGWLS
MSMEG_6471|M.smegmatis_MC2_155 DADVCIVGAGYTGLWTAYYLKKADPSLRIAILEARFAGFGASGRNGGWLS
MAB_2283|M.abscessus_ATCC_1997 DVDVLVIGAGLAGLAAAYFVTELRPELSVAVLEAKHVGAGATGRSTGIVS
TH_1303|M.thermoresistible__bu RADVVVVGAGITGLITAVLLARGG--KDVLVVEAAYVGAGATGNTTAKIS
.** ::*** :** :* : . : :::* ..* **:*.. . :*
Mflv_1109|M.gilvum_PYR-GCK GLVPGDRERMARQYGRDGVVAWQRALNDAVDEVIDVAAQEGIDAGIVKGG
Mvan_5703|M.vanbaalenii_PYR-1 GLVPGDRERMARRYGRDGVVAWQRALNDAVDEVIAVAGREGIDAGIVKGG
MSMEG_6471|M.smegmatis_MC2_155 GLVPGDRHRMAKLYGRDKVLAWQKALNEAVDEVIAVADAEGIDAGAVKGG
MAB_2283|M.abscessus_ATCC_1997 PGLSMPMAAFRRKYGDDAAIASFDATFHGVGLLRDLVAKENIDCDARDEP
TH_1303|M.thermoresistible__bu VLQGSRMSKILAKHGPRRARQYVEGNLEGLEWLVRHCAAHGLSVQREDAY
: :* . . ..: : ..:. .
Mflv_1109|M.gilvum_PYR-GCK NLEVARNRAQVRRLAAAVDAERRWQVDGVEVLT-----KSEAAQRIALDG
Mvan_5703|M.vanbaalenii_PYR-1 TLEVARNAAQASRLAAAVEAERRWQVDGIEPLT-----ADEATRRIRLDG
MSMEG_6471|M.smegmatis_MC2_155 TLEIARNPAQAARLAASIAEERSWGVD-VTELS-----REQAAERIRFDG
MAB_2283|M.abscessus_ATCC_1997 HTLVALTDRSLARMVTHLEN--LAELGREVPWL-----SSQEVVQWAGAG
TH_1303|M.thermoresistible__bu TFAQSLQGVPAARTEYLAAKIAGLDVEWVDDAEGGVPFPFHGAVRLADQA
: * : . . : .
Mflv_1109|M.gilvum_PYR-GCK VISAYYSPHCARIQPAQLVRGLADAVERLGVVIYERSPVTEITAGR----
Mvan_5703|M.vanbaalenii_PYR-1 VVAGYHNPHCARIQPAQLVRGLADTVERLGVAVYERSPVIEIGAGR----
MSMEG_6471|M.smegmatis_MC2_155 LVSAYHNPHCARIQPAALARGLADAVERLGVTIYEQSPVTEISQGR----
MAB_2283|M.abscessus_ATCC_1997 YKAGFAYRDAMVVDPYRLVTGMADILRRRGAPVYEHSPVISIEADATGVC
TH_1303|M.thermoresistible__bu QFDPMPLLDSLVVELEERGGRLVQGLRVHKVSGRGDGLTLHARSGAGDEF
.. :: :.: :. . . . .
Mflv_1109|M.gilvum_PYR-GCK AATPWGAVSAP-VVLRATEGFTAGLPGLKRRWLPMNSS------------
Mvan_5703|M.vanbaalenii_PYR-1 AVTPWGAVTAP-VVLRATEGFTAALPGLKRRWLPMNSS------------
MSMEG_6471|M.smegmatis_MC2_155 AVTARGTVRAP-IVLRATEGFTAALPGQRRAWLPMNSS------------
MAB_2283|M.abscessus_ATCC_1997 VFTARAQVRAR-HAFLATDGYSGTLNPLKSSVIPLRTH------------
TH_1303|M.thermoresistible__bu DLRADRCVLATGIPILDRGGFFARLEPNRSYCLAYEVPGEITRGMYISTD
. * * : *: . * : :. .
Mflv_1109|M.gilvum_PYR-GCK ----MIATEPVPESVWAEIGWEGRETLGDTAHGFFYAQRTVDNRIAIGG-
Mvan_5703|M.vanbaalenii_PYR-1 ----MIATDPVPEQVWDTIGWQGRETLGDTAHGFFYAQRTVDDRIAIGG-
MSMEG_6471|M.smegmatis_MC2_155 ----MIATEPIPAHVWDEIGWQGRETVGDSAHGFFYAQRTVDDRIAIGG-
MAB_2283|M.abscessus_ATCC_1997 ----LLATAPLTEGQLAELGWSGRGAIIDQRTFFNYYRMSADKRVVFGGG
TH_1303|M.thermoresistible__bu SPTRSLRYAPTGAGDLLIVGGAGHPVGHEKNPASSVAELDEWARRHFPG-
: * :* *: . : . * : *
Mflv_1109|M.gilvum_PYR-GCK -RSVPYRFGSRTDR-------DGRLPERTIKNLTATLHSILPQVAHVPIA
Mvan_5703|M.vanbaalenii_PYR-1 -RSVPYRFASRIDR-------DGRVPERTIAHLTATLHSILPQVADVPIA
MSMEG_6471|M.smegmatis_MC2_155 -RSVPYRYASRTDV-------DGQVPPKTIRLLTDVLHAILPQVRDVPIA
MAB_2283|M.abscessus_ATCC_1997 PAFVPSRIPSRDIK-------RSRVIQQRVR---RELTERFPVLADVEID
TH_1303|M.thermoresistible__bu -AQQRYFWSAQDYSPIDDLPYVGPILPGNESIFVAIGFDKWGMTNGAAAA
:: . : .
Mflv_1109|M.gilvum_PYR-GCK HGWCG-VLAVPRDWEASVDFDP-ATGLGWAGGYVG-HGVTATNLAGRTLT
Mvan_5703|M.vanbaalenii_PYR-1 HGWCG-VLAVPRDWEATVDFDR-ETGLGWAGGYVG-HGVTATNLAARTLT
MSMEG_6471|M.smegmatis_MC2_155 HGWCG-VLAVPRDWEASVVLDR-ATGLGWAGGYVG-HGVTATNLAGRTLA
MAB_2283|M.abscessus_ATCC_1997 AAWSG-ITASSFDRNPVVGPVPGMDGLWFAGSWCG-HGFSTSVDTGWRFA
TH_1303|M.thermoresistible__bu LALSSRILGGRTDWAEAFASWSPHEVSGIPKAMMLNLQVGMYLARGWLTP
. .. : . * . . . . . .
Mflv_1109|M.gilvum_PYR-GCK DLVLTRESP------LTRLPWVGHECKDWEPEPLRWIGVRGMYLAYKAAD
Mvan_5703|M.vanbaalenii_PYR-1 DLVLGRQSP------LTGLPWVGHRSKSWEPEPLRWLGVRGMYLAYKAAD
MSMEG_6471|M.smegmatis_MC2_155 DLVCNRATP------LTELPWVGHRSRNWEPEPLRWLGVRGLYIAYKLAD
MAB_2283|M.abscessus_ATCC_1997 KTLVGEPLP------AN-IPWFRSGAQRVPTTLLRNVATGAYLKALDAAD
TH_1303|M.thermoresistible__bu VTRTGDRSPDDGCGVVSGPPWHLQARSRVDGVEHRVSPVCPHLGGIVNWN
* . ** * . . :
Mflv_1109|M.gilvum_PYR-GCK WHEARGTKRTSPIAVVANRITGR----------
Mvan_5703|M.vanbaalenii_PYR-1 WHEARGARRTSPIAVVADKIAGRPH--------
MSMEG_6471|M.smegmatis_MC2_155 RHEAGGRPTTSPIAKVADVITRKPH--------
MAB_2283|M.abscessus_ATCC_1997 ALDAKTSNPPQVARPTAGRQTSRGTTTLAEADK
TH_1303|M.thermoresistible__bu DADQAWECPLHGSRFAPDGALLEGPATRGLTAS
: ... .