For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PTSPLGCDNLPVPTRAPVNGYVSHWFDELPFSRGPLPGSRDADVCIVGAGYTGLWTAYYLKRADPSLRIV VLEARFAGFGASGRNGGWLSGLVPGDRERMARRYGRDGVVAWQRALNDAVDEVIAVAGREGIDAGIVKGG TLEVARNAAQASRLAAAVEAERRWQVDGIEPLTADEATRRIRLDGVVAGYHNPHCARIQPAQLVRGLADT VERLGVAVYERSPVIEIGAGRAVTPWGAVTAPVVLRATEGFTAALPGLKRRWLPMNSSMIATDPVPEQVW DTIGWQGRETLGDTAHGFFYAQRTVDDRIAIGGRSVPYRFASRIDRDGRVPERTIAHLTATLHSILPQVA DVPIAHGWCGVLAVPRDWEATVDFDRETGLGWAGGYVGHGVTATNLAARTLTDLVLGRQSPLTGLPWVGH RSKSWEPEPLRWLGVRGMYLAYKAADWHEARGARRTSPIAVVADKIAGRPH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5703 | - | - | 100% (472) | FAD dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3170 | - | 6e-45 | 30.82% (438) | FAD dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0117 | - | 4e-06 | 28.41% (176) | FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1109 | - | 0.0 | 85.59% (458) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2283 | - | 9e-38 | 29.89% (455) | putative oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2749 | - | 2e-05 | 28.95% (190) | FAD dependent oxidoreductase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_6471 | - | 0.0 | 76.87% (454) | glycine/D-amino acid oxidase |
| M. thermoresistible (build 8) | TH_1303 | - | 2e-05 | 38.24% (68) | iron-sulfur binding oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5703|M.vanbaalenii_PYR-1 --------MPTSPLGCDNLPVPTRAPVNGYVSHWFDELPFSRGPLPGSRD
Mflv_1109|M.gilvum_PYR-GCK --------------------MHTRA-LNGQVSHWFDGLPISRGPLPGSRD
MSMEG_6471|M.smegmatis_MC2_155 MAEWQEVLCGHRVISNSWQNLTVLNTVNGQISHWFDTLPTPRAPLPGDQD
MAV_2749|M.avium_104 -------------------------MTSLWMSERTERPWAASQLDQGPAS
TH_1303|M.thermoresistible__bu -------------------------MTSLWLADRTNQPPPPRTLDAGDRR
MAB_2283|M.abscessus_ATCC_1997 -----------------MNGTEIGHLAETAPIWWPGSPESAAPITDGRHD
. . *
Mvan_5703|M.vanbaalenii_PYR-1 ADVCIVGAGYTGLWTAYYLKRADPSLRIVVLEARFAGFGASGRNGGWLSG
Mflv_1109|M.gilvum_PYR-GCK ADVCIVGAGYTGLWTAYYLKRADPSLRVVVLDARFAGYGASGRNGGWLSG
MSMEG_6471|M.smegmatis_MC2_155 ADVCIVGAGYTGLWTAYYLKKADPSLRIAILEARFAGFGASGRNGGWLSG
MAV_2749|M.avium_104 ADVIVVGAGITGLMTAALLARAGK--DVLVLEARTVGACATANTTAKISL
TH_1303|M.thermoresistible__bu ADVVVVGAGITGLITAVLLARGGK--DVLVVEAAYVGAGATGNTTAKISV
MAB_2283|M.abscessus_ATCC_1997 VDVLVIGAGLAGLAAAYFVTELRPELSVAVLEAKHVGAGATGRSTGIVSP
.** ::*** :** :* : . : :::* .* *:... . :*
Mvan_5703|M.vanbaalenii_PYR-1 LVPGDRERMARRYGRDGVVAWQRALNDAVDEVIAVAGREGIDAGIVKGGT
Mflv_1109|M.gilvum_PYR-GCK LVPGDRERMARQYGRDGVVAWQRALNDAVDEVIDVAAQEGIDAGIVKGGN
MSMEG_6471|M.smegmatis_MC2_155 LVPGDRHRMAKLYGRDKVLAWQKALNEAVDEVIAVADAEGIDAGAVKGGT
MAV_2749|M.avium_104 LQGSQLSKVLPRHGREVTRAYVDGNREGQEWVLGHCEAHGVAVQREDAYT
TH_1303|M.thermoresistible__bu LQGSRMSKILAKHGPRRARQYVEGNLEGLEWLVRHCAAHGLSVQREDAYT
MAB_2283|M.abscessus_ATCC_1997 GLSMPMAAFRRKYGDDAAIASFDATFHGVGLLRDLVAKENIDCDARDEPH
. :* . . .. : ..: .
Mvan_5703|M.vanbaalenii_PYR-1 LEVARN---AAQASRLAAAVEAERRWQVDGIEPLTADEATRRIRLDGVVA
Mflv_1109|M.gilvum_PYR-GCK LEVARN---RAQVRRLAAAVDAERRWQVDGVEVLTKSEAAQRIALDGVIS
MSMEG_6471|M.smegmatis_MC2_155 LEIARN---PAQAARLAASIAEERSWGVD-VTELSREQAAERIRFDGLVS
MAV_2749|M.avium_104 YAQSVRGVPSARAEFEACQAVGLPVVWQDDAE--VPFAYHGGVRLADQAQ
TH_1303|M.thermoresistible__bu FAQSLQGVPAARTEYLAAKIAGLDVEWVDDAEGGVPFPFHGAVRLADQAQ
MAB_2283|M.abscessus_ATCC_1997 TLVALT---DRSLARMVTHLEN--LAELGREVPWLSSQEVVQWAGAGYKA
: . . .
Mvan_5703|M.vanbaalenii_PYR-1 GYHNPHCARIQPAQLVRG--LADTVERLGVAVYERSPVIEIGAG------
Mflv_1109|M.gilvum_PYR-GCK AYYSPHCARIQPAQLVRG--LADAVERLGVVIYERSPVTEITAG------
MSMEG_6471|M.smegmatis_MC2_155 AYHNPHCARIQPAALARG--LADAVERLGVTIYEQSPVTEISQG------
MAV_2749|M.avium_104 FDPMPFLDSLAVELLGRGGRLVEHTRVRRVSWRGKGVRVHANQGSDAAGH
TH_1303|M.thermoresistible__bu FDPMPLLDSLVVELEERGGRLVQGLRVHKVSGRGDGLTLHARSG---AGD
MAB_2283|M.abscessus_ATCC_1997 GFAYRDAMVVDPYRLVTG--MADILRRRGAPVYEHSPVISIEADATG---
: * :.: . . . .
Mvan_5703|M.vanbaalenii_PYR-1 --RAVTPWGAVTAPVVLRATEGFTAALPGLKRRWLPMNSS--------MI
Mflv_1109|M.gilvum_PYR-GCK --RAATPWGAVSAPVVLRATEGFTAGLPGLKRRWLPMNSS--------MI
MSMEG_6471|M.smegmatis_MC2_155 --RAVTARGTVRAPIVLRATEGFTAALPGQRRAWLPMNSS--------MI
MAV_2749|M.avium_104 DVELHADQLVLATGIPILDRGGYFARVKPSRSYCLAFKVPGNITRPMMIS
TH_1303|M.thermoresistible__bu EFDLRADRCVLATGIPILDRGGFFARLEPNRSYCLAYEVPGEITRGMYIS
MAB_2283|M.abscessus_ATCC_1997 -VCVFTARAQVRARHAFLATDGYSGTLNPLKSSVIPLRTH--------LL
: : : : *: . : : :. . :
Mvan_5703|M.vanbaalenii_PYR-1 ATDPVPEQVWDTIGWQGRETLGDTAHGFFYAQRTVDDRIAIGGRSVPYRF
Mflv_1109|M.gilvum_PYR-GCK ATEPVPESVWAEIGWEGRETLGDTAHGFFYAQRTVDNRIAIGGRSVPYRF
MSMEG_6471|M.smegmatis_MC2_155 ATEPIPAHVWDEIGWQGRETVGDSAHGFFYAQRTVDDRIAIGGRSVPYRY
MAV_2749|M.avium_104 TDSPTRSVRYAPVPDGERLIVGGAGHTVGREKSPSAALDELSAWTRKHFP
TH_1303|M.thermoresistible__bu TDSPTRSLRYAPTGAGDLLIVGGAGHPVGHEKNPASSVAELDEWARRHFP
MAB_2283|M.abscessus_ATCC_1997 ATAPLTEGQLAELGWSGRGAIIDQRTFFNYYRMSADKRVVFGG-GPAFVP
: * : . . : . :. .
Mvan_5703|M.vanbaalenii_PYR-1 ASRIDRDGRVPERTIAHLTATLHSILPQVADVPIAHGWCGVLAVPRDWEA
Mflv_1109|M.gilvum_PYR-GCK GSRTDRDGRLPERTIKNLTATLHSILPQVAHVPIAHGWCGVLAVPRDWEA
MSMEG_6471|M.smegmatis_MC2_155 ASRTDVDGQVPPKTIRLLTDVLHAILPQVRDVPIAHGWCGVLAVPRDWEA
MAV_2749|M.avium_104 GAVQTHFWSAQDYTPIDHLPYVGPILPNSETIFVATGFNKWGMTNGAAAA
TH_1303|M.thermoresistible__bu GAQQRYFWSAQDYSPIDDLPYVGPILPGNESIFVAIGFDKWGMTNGAAAA
MAB_2283|M.abscessus_ATCC_1997 SRIPSRDIKRSRVIQQRVRRELTERFPVLADVEIDAAWSGITASSFDRNP
. : :* : : .: .
Mvan_5703|M.vanbaalenii_PYR-1 TVDFDRETG--LGWAGGYVGHGVTATN-LAARTLTDLVLGRQSP---LTG
Mflv_1109|M.gilvum_PYR-GCK SVDFDPATG--LGWAGGYVGHGVTATN-LAGRTLTDLVLTRESP---LTR
MSMEG_6471|M.smegmatis_MC2_155 SVVLDRATG--LGWAGGYVGHGVTATN-LAGRTLADLVCNRATP---LTE
MAV_2749|M.avium_104 LALSSRILGGRMDWARAFASWSPHELSGLATAVQANLEVGFNLTKGWITP
TH_1303|M.thermoresistible__bu LALSSRILGGRTDWAEAFASWSPHEVSGIPKAMMLNLQVGMYLARGWLTP
MAB_2283|M.abscessus_ATCC_1997 VVGPVPGMDG-LWFAGSWCGHG-FSTSVDTGWRFAKTLVGEPLP----AN
. . :* .: . . . . . . :
Mvan_5703|M.vanbaalenii_PYR-1 LPWVGHRS-----------KSWEPEPLRWLG-----------VRGMYLAY
Mflv_1109|M.gilvum_PYR-GCK LPWVGHEC-----------KDWEPEPLRWIG-----------VRGMYLAY
MSMEG_6471|M.smegmatis_MC2_155 LPWVGHRS-----------RNWEPEPLRWLG-----------VRGLYIAY
MAV_2749|M.avium_104 AVRIGRRSPVDGDGGVVSGPPWHLQARCRVDGTEHRVSPVCPHLGGIVNW
TH_1303|M.thermoresistible__bu VTRTGDRSPDDG-CGVVSGPPWHLQARSRVDGVEHRVSPVCPHLGGIVNW
MAB_2283|M.abscessus_ATCC_1997 IPWFRSGA-----------QRVPTTLLRNVATG--------AYLKALDAA
. :
Mvan_5703|M.vanbaalenii_PYR-1 KAAD--WHEARGARRTSPIAVVADKIAGRPH----
Mflv_1109|M.gilvum_PYR-GCK KAAD--WHEARGTKRTSPIAVVANRITGR------
MSMEG_6471|M.smegmatis_MC2_155 KLAD--RHEAGGRPTTSPIAKVADVITRKPH----
MAV_2749|M.avium_104 NDADKAWECPLHGSRFAPDGTLLEGPATRDLTASR
TH_1303|M.thermoresistible__bu NDADQAWECPLHGSRFAPDGALLEGPATRGLTAS-
MAB_2283|M.abscessus_ATCC_1997 DALDAKTSNPPQVARPTAGRQTSRGTTTLAEADK-
. * . :. :