For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AEWQEVLCGHRVISNSWQNLTVLNTVNGQISHWFDTLPTPRAPLPGDQDADVCIVGAGYTGLWTAYYLKK ADPSLRIAILEARFAGFGASGRNGGWLSGLVPGDRHRMAKLYGRDKVLAWQKALNEAVDEVIAVADAEGI DAGAVKGGTLEIARNPAQAARLAASIAEERSWGVDVTELSREQAAERIRFDGLVSAYHNPHCARIQPAAL ARGLADAVERLGVTIYEQSPVTEISQGRAVTARGTVRAPIVLRATEGFTAALPGQRRAWLPMNSSMIATE PIPAHVWDEIGWQGRETVGDSAHGFFYAQRTVDDRIAIGGRSVPYRYASRTDVDGQVPPKTIRLLTDVLH AILPQVRDVPIAHGWCGVLAVPRDWEASVVLDRATGLGWAGGYVGHGVTATNLAGRTLADLVCNRATPLT ELPWVGHRSRNWEPEPLRWLGVRGLYIAYKLADRHEAGGRPTTSPIAKVADVITRKPH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6471 | - | - | 100% (479) | glycine/D-amino acid oxidase |
| M. smegmatis MC2 155 | MSMEG_3663 | - | 1e-49 | 33.03% (442) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1109 | - | 0.0 | 74.89% (450) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2283 | - | 9e-36 | 27.89% (441) | putative oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2749 | - | 2e-05 | 31.58% (95) | FAD dependent oxidoreductase domain-containing protein |
| M. thermoresistible (build 8) | TH_2138 | - | 2e-08 | 25.26% (285) | D-amino-acid dehydrogenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5703 | - | 0.0 | 76.87% (454) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1109|M.gilvum_PYR-GCK --------------------MHTRA-LNGQVSHWFDGLPISRGPLP-GSR
Mvan_5703|M.vanbaalenii_PYR-1 --------MPTSPLGCDNLPVPTRAPVNGYVSHWFDELPFSRGPLP-GSR
MSMEG_6471|M.smegmatis_MC2_155 MAEWQEVLCGHRVISNSWQNLTVLNTVNGQISHWFDTLPTPRAPLP-GDQ
MAB_2283|M.abscessus_ATCC_1997 ------------------MNGTEIGHLAETAPIWWPGSPESAAPITDGRH
TH_2138|M.thermoresistible__bu --------------------------MSQRFAERVDGGPRS---------
MAV_2749|M.avium_104 --------------------------MTSLWMSERTERPWAASQLDQGPA
: * .
Mflv_1109|M.gilvum_PYR-GCK DADVCIVGAGYTGLWTAYYLKRADPSLRVVVLDARFAGYGASGRNGGWLS
Mvan_5703|M.vanbaalenii_PYR-1 DADVCIVGAGYTGLWTAYYLKRADPSLRIVVLEARFAGFGASGRNGGWLS
MSMEG_6471|M.smegmatis_MC2_155 DADVCIVGAGYTGLWTAYYLKKADPSLRIAILEARFAGFGASGRNGGWLS
MAB_2283|M.abscessus_ATCC_1997 DVDVLVIGAGLAGLAAAYFVTELRPELSVAVLEAKHVGAGATGRSTGIVS
TH_2138|M.thermoresistible__bu ---AIVIGAGIVGLSTAWFLQERG--VDVCVVDRTGVAAGASWGNAGWIS
MAV_2749|M.avium_104 SADVIVVGAGITGLMTAALLARAG--KDVLVLEARTVGACATANTTAKIS
. ::*** .** :* : . : ::: .. *: . . :*
Mflv_1109|M.gilvum_PYR-GCK GLVPGDR-ERMARQYGRDGVVAWQRALNDAVD-EVIDVAAQ---EGIDAG
Mvan_5703|M.vanbaalenii_PYR-1 GLVPGDR-ERMARRYGRDGVVAWQRALNDAVD-EVIAVAGR---EGIDAG
MSMEG_6471|M.smegmatis_MC2_155 GLVPGDR-HRMAKLYGRDKVLAWQKALNEAVD-EVIAVADA---EGIDAG
MAB_2283|M.abscessus_ATCC_1997 PGLSMPM-AAFRRKYGDDAAIASFDATFHGVG-LLRDLVAK---ENIDCD
TH_2138|M.thermoresistible__bu PGLAIPLNEPGVLRYGLRNLLSPTAPLHLPLTRDLRQWAFL---TRFAAN
MAV_2749|M.avium_104 -LLQGSQLSKVLPRHGREVTRAYVDGNREGQEWVLGHCEAHGVAVQREDA
: :* : :
Mflv_1109|M.gilvum_PYR-GCK IVKGGNLEVARNRAQVRRLAAAVDAERRWQVDGVEVLTKSE---------
Mvan_5703|M.vanbaalenii_PYR-1 IVKGGTLEVARNAAQASRLAAAVEAERRWQVDGIEPLTADE---------
MSMEG_6471|M.smegmatis_MC2_155 AVKGGTLEIARNPAQAARLAASIAEERSWGVD-VTELSREQ---------
MAB_2283|M.abscessus_ATCC_1997 ARDEPHTLVALTDRSLARMVTHLEN--LAELGREVPWLSSQ---------
TH_2138|M.thermoresistible__bu CRRSSWTRALLANKPLN--DEAIEAYDVLTANGVDAPVTDA---------
MAV_2749|M.avium_104 YTYAQSVRGVPSARAEFEACQAVGLPVVWQDDAEVPFAYHGGVRLADQAQ
: .
Mflv_1109|M.gilvum_PYR-GCK ----------AAQRIALDGVISAYYSPHCARIQPAQLVRGLADAVERLGV
Mvan_5703|M.vanbaalenii_PYR-1 ----------ATRRIRLDGVVAGYHNPHCARIQPAQLVRGLADTVERLGV
MSMEG_6471|M.smegmatis_MC2_155 ----------AAERIRFDGLVSAYHNPHCARIQPAALARGLADAVERLGV
MAB_2283|M.abscessus_ATCC_1997 ----------EVVQWAGAGYKAGFAYRDAMVVDPYRLVTGMADILRRRGA
TH_2138|M.thermoresistible__bu ----------PITAVFRDPREAGRLRDELRRVAETGRDVEVTELS---GA
MAV_2749|M.avium_104 FDPMPFLDSLAVELLGRGGRLVEHTRVRRVSWRGKGVRVHANQGSDAAGH
: *
Mflv_1109|M.gilvum_PYR-GCK VIYERSPVTEITAGR----AATPWGAVSAPVVLRATEGFTAGLPGLKRRW
Mvan_5703|M.vanbaalenii_PYR-1 AVYERSPVIEIGAGR----AVTPWGAVTAPVVLRATEGFTAALPGLKRRW
MSMEG_6471|M.smegmatis_MC2_155 TIYEQSPVTEISQGR----AVTARGTVRAPIVLRATEGFTAALPGQRRAW
MAB_2283|M.abscessus_ATCC_1997 PVYEHSPVISIEADATGVCVFTARAQVRARHAFLATDGYSGTLNPLKSSV
TH_2138|M.thermoresistible__bu DLRERVPLASAEITVG---LEIHGQRYVDPARFVQALADSVVDRGATIHR
MAV_2749|M.avium_104 DVELHADQLVLATGIPILDRGGYFARVKPSRSYCLAFKVPGNITRPMMIS
: : : .
Mflv_1109|M.gilvum_PYR-GCK LPMNSSMIATEPVPESVWAEIGWEGRETLGDTAHGFFYAQRTVDNRIAIG
Mvan_5703|M.vanbaalenii_PYR-1 LPMNSSMIATDPVPEQVWDTIGWQGRETLGDTAHGFFYAQRTVDDRIAIG
MSMEG_6471|M.smegmatis_MC2_155 LPMNSSMIATEPIPAHVWDEIGWQGRETVGDSAHGFFYAQRTVDDRIAIG
MAB_2283|M.abscessus_ATCC_1997 IPLRTHLLATAPLTEGQLAELGWSGRGAIIDQRTFFNYYRMSADKRVVFG
TH_2138|M.thermoresistible__bu MDITGVDSGPGGVTVHSAGGQELSAGAVVIATGAWLHQLAQRWVRVPVQA
MAV_2749|M.avium_104 TDSPTRSVRYAPVPDGERLIVGGAGHTVGREKSPSAALDELSAWTRKHFP
:. . .
Mflv_1109|M.gilvum_PYR-GCK G--RSVPYRFGSRTDRD-----GRLPERTIKNLTATLHSILPQVAHVPIA
Mvan_5703|M.vanbaalenii_PYR-1 G--RSVPYRFASRIDRD-----GRVPERTIAHLTATLHSILPQVADVPIA
MSMEG_6471|M.smegmatis_MC2_155 G--RSVPYRYASRTDVD-----GQVPPKTIRLLTDVLHAILPQVRDVPIA
MAB_2283|M.abscessus_ATCC_1997 GGPAFVPSRIPSRDIKR-----SRVIQQRVR---RELTERFPVLADVEID
TH_2138|M.thermoresistible__bu G--RGYSFTVPVDRPVP-----APVYLPEVRVACTPCAAGLRVAGTMEFR
MAV_2749|M.avium_104 GAVQTHFWSAQDYTPIDHLPYVGPILPNSETIFVATGFNKWGMTNGAAAA
* . :
Mflv_1109|M.gilvum_PYR-GCK HGWCG-VLAVPRDWEASVDFDP-ATGLGWAG-GYVGHGVTATNLAGRTLT
Mvan_5703|M.vanbaalenii_PYR-1 HGWCG-VLAVPRDWEATVDFDR-ETGLGWAG-GYVGHGVTATNLAARTLT
MSMEG_6471|M.smegmatis_MC2_155 HGWCG-VLAVPRDWEASVVLDR-ATGLGWAG-GYVGHGVTATNLAGRTLA
MAB_2283|M.abscessus_ATCC_1997 AAWSG-ITASSFDRNPVVGPVPGMDGLWFAG-SWCGHGFSTSVDTGWRFA
TH_2138|M.thermoresistible__bu DPDAP-LISKRVD-AIVAAARPLLDGVRWDERGPSWVGPRPVTPDGRPLI
MAV_2749|M.avium_104 LALSSRILGGRMDWARAFASWSPHELSGLATAVQANLEVGFNLTKGWITP
. : . * .
Mflv_1109|M.gilvum_PYR-GCK DLVLTRESPLTR-------LPWVGHECKDWEPEPLRWIGVRGMYLAYKAA
Mvan_5703|M.vanbaalenii_PYR-1 DLVLGRQSPLTG-------LPWVGHRSKSWEPEPLRWLGVRGMYLAYKAA
MSMEG_6471|M.smegmatis_MC2_155 DLVCNRATPLTE-------LPWVGHRSRNWEPEPLRWLGVRGLYIAYKLA
MAB_2283|M.abscessus_ATCC_1997 KTLVGEPLPAN--------IPWFRSGAQRVPTTLLRNVATGAYLKALDAA
TH_2138|M.thermoresistible__bu GAVAED--------------VYVAAGHGMWG---LTHGPVTGRLLAEQIT
MAV_2749|M.avium_104 AVRIGRRSPVDGDGGVVSGPPWHLQARCRVDGTEHRVSPVCPHLGGIVNW
: . .
Mflv_1109|M.gilvum_PYR-GCK DWHEARGTKRTSPIAVVANRITGR-----------
Mvan_5703|M.vanbaalenii_PYR-1 DWHEARGARRTSPIAVVADKIAGRPH---------
MSMEG_6471|M.smegmatis_MC2_155 DRHEAGGRPTTSPIAKVADVITRKPH---------
MAB_2283|M.abscessus_ATCC_1997 DALDAKTSNPPQVARPTAGRQTSRGTTTLAEADK-
TH_2138|M.thermoresistible__bu TGKQPDVLDEFDPLR--------------------
MAV_2749|M.avium_104 NDADKAWECPLHGSRFAPDGTLLEGPATRDLTASR
: