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GEADIAVVLALAAALFMAVGDVIHQRSAHEITDEPVGHLELFLKLLRDGRWWLGSGVAAMGFACQAAALG LGSVLLVQALLVTSLLFALPLSARLSHRRVTRWEWIWAVLLAGAVAVIVTVGNPTEGATRASLQTWIEVA AVLGPVLVLCLVGARMSSGAMSAVLTGVVSGALWGVFAVLTKTVVHRLDVTSLAGVVELLSTPELYAWAV VGILGTSTQQAAFRAGSLTASLPTMTVTEPLVGCALGVVVLGETMRPGETGWVLLIAAAVTVVVATAALA RGEATDLQPATV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3964 | - | - | 100% (293) | hypothetical protein Mflv_3964 |
| M. gilvum PYR-GCK | Mflv_1077 | - | 9e-55 | 45.28% (265) | hypothetical protein Mflv_1077 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2748c | - | 5e-74 | 53.33% (285) | hypothetical protein Mb2748c |
| M. tuberculosis H37Rv | Rv2729c | - | 2e-73 | 52.98% (285) | hypothetical protein Rv2729c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2553 | - | 2e-14 | 28.99% (238) | putative integral membrane protein |
| M. marinum M | MMAR_1984 | - | 8e-81 | 56.49% (285) | hypothetical protein MMAR_1984 |
| M. avium 104 | MAV_2125 | - | 5e-87 | 56.70% (291) | hypothetical protein MAV_2125 |
| M. smegmatis MC2 155 | MSMEG_2732 | - | 1e-113 | 70.65% (293) | hypothetical protein MSMEG_2732 |
| M. thermoresistible (build 8) | TH_3271 | - | 1e-54 | 44.13% (281) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3372 | - | 5e-81 | 56.49% (285) | hypothetical protein MUL_3372 |
| M. vanbaalenii PYR-1 | Mvan_2432 | - | 1e-125 | 77.32% (291) | hypothetical protein Mvan_2432 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2748c|M.bovis_AF2122/97 MASVEFATILALG--AALLAGIGYVTLQRSARQVTAEEYVGHLTLFHLSL
Rv2729c|M.tuberculosis_H37Rv MASVEFATILALG--AALLAGIGYVTLQRSARQVTAEEYVGHFTLFHLSL
MMAR_1984|M.marinum_M MTTTEIAAVLALG--AAFASALGNVTRQRSAQEITDEQ-VGHLELFWLSL
MUL_3372|M.ulcerans_Agy99 MTTTEIAAVLALG--AAFASALGNVTRQRSAQEITDEQ-VGHLELFWLSL
Mflv_3964|M.gilvum_PYR-GCK MGEADIAVVLALA--AALFMAVGDVIHQRSAHEITDEP-VGHLELFLKLL
Mvan_2432|M.vanbaalenii_PYR-1 MAKADLAALLALA--AAFFMAVGDVIHQRSARGVTDEP-IGHLELFGRLL
MSMEG_2732|M.smegmatis_MC2_155 MNRADIAALLALG--AALCIAIGDVIHQRSAHDVTDDS-VSHLGLFKRLL
MAV_2125|M.avium_104 MGRTDIATVLAVA--AALMVGAGDVAQQQSAQQVTDQP-VGTVALFRRLL
TH_3271|M.thermoresistible__bu VLGQGLAVLLAVC--AAVFAAVGIVVRQRATMDVPPEKGVSTVMIATLVR
MAB_2553|M.abscessus_ATCC_1997 MLIGIAAAMLACFGYGTASVLQGYGARQSSTEVGVAADHGPSLKSTVAAA
: *.:** .: * * :: .
Mb2748c|M.bovis_AF2122/97 RHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLIDARLT
Rv2729c|M.tuberculosis_H37Rv RHALWWLGSLAAVASFTLQAIALTMGSVVLVQSLQATALLFALLIDARLT
MMAR_1984|M.marinum_M RDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFALPIYARVT
MUL_3372|M.ulcerans_Agy99 RDSRWWLGALGAIANYLLQAAALTLGSVVLVSALQVTALLFALPIYARVT
Mflv_3964|M.gilvum_PYR-GCK RDGRWWLGSGVAAMGFACQAAALGLGSVLLVQALLVTSLLFALPLSARLS
Mvan_2432|M.vanbaalenii_PYR-1 RDGRWWVGSGTAAAGFVLQAAALGLGSVLLVQALLVTSLLFALPISARLS
MSMEG_2732|M.smegmatis_MC2_155 RDGRWWLGSGVAAAGFALQAAALGLGSVLLVQALLVTSLLFALPINARLT
MAV_2125|M.avium_104 RDRRWWTGSLVAAGGFGFQAAALGFGSVVLVQALLVTSLLFALLISARVN
TH_3271|M.thermoresistible__bu R-RLWWIGTGAAVAGYALQAAALAFGSLILVQPILVSALLFALPLSARLG
MAB_2553|M.abscessus_ATCC_1997 LTPAFIAGMVLDLVGFAGSLVSARLIPLFLSQTIMSANLAVTAVLGIAVL
: * .: . : : .:.* ..: : * .: : :
Mb2748c|M.bovis_AF2122/97 HHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAVVVVPA
Rv2729c|M.tuberculosis_H37Rv HHRCTPREWMWAVLLAGAVAVIVMSGNPAAGTTRAPFSTWAVVAVVVVPA
MMAR_1984|M.marinum_M RRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVVASVLGPV
MUL_3372|M.ulcerans_Agy99 RRRVTRWEWTWAVLLAVSLAVVVIVGDPDVGVSRGSLATWMVVASVLGPV
Mflv_3964|M.gilvum_PYR-GCK HRRVTRWEWIWAVLLAGAVAVIVTVGNPTEGATRASLQTWIEVAAVLGPV
Mvan_2432|M.vanbaalenii_PYR-1 HRRVTRWELLWAAVLAGAVAVIVTVGNPTEGASRASLETWLGVATVLGPL
MSMEG_2732|M.smegmatis_MC2_155 RRRVTRWEWMWAALLAGAVAVIVTVGNPTAGHARAPWEAWTLVLAVLGPA
MAV_2125|M.avium_104 RRRITGRQAVWALLLAAAVAVVVTVGDPQEGTPRGSLQTWTIVALVMGPA
TH_3271|M.thermoresistible__bu ARRVSRGEWAWAAVLTVALAAFVLIAKPKPGDYQASIPGTVVVTVACVAG
MAB_2553|M.abscessus_ATCC_1997 GVRLQRRDWLAICAVLLSLCVLAATAGPRGEDSAPPAIHWGVLTVSIS--
* : : ::.... . * . :
Mb2748c|M.bovis_AF2122/97 VVLCVVGARIASGSLSAVLLAVASSATLAVFTVLTKGVVTELGE----GF
Rv2729c|M.tuberculosis_H37Rv VVLCVVGARIASGSLSAVLLAVASSATLAVFTVLTKGVVTELGE----GF
MMAR_1984|M.marinum_M MVFCVLGARIWSGSVAAVLLAVVSGCSLALFAVLTKAVVEVVGG----GA
MUL_3372|M.ulcerans_Agy99 MVFCVLGARIWSGSVAAVLLAVVSGCSLALFAVLTKAVVEVVGG----GA
Mflv_3964|M.gilvum_PYR-GCK LVLCLVGARMSSGAMSAVLTGVVSGALWGVFAVLTKTVVHRLDVTSLAGV
Mvan_2432|M.vanbaalenii_PYR-1 LALCVVGATVWSGPISAVLMAVVSGALWGLFAVLTKAVVHRLDVTSLAGV
MSMEG_2732|M.smegmatis_MC2_155 VAVCLVGARIFTGARSAVLLALVSGALWGVFAVLTKGVVNHLLVHSWGGV
MAV_2125|M.avium_104 LIGCVLGARLYPGPVAALLLGLMSGSLWGLFAVLTKGVVDQLDR----GI
TH_3271|M.thermoresistible__bu VTVCVVLAVRSLGWRRALLLATAVGVLFGVVAVLTKVWLHKLFTG---GV
MAB_2553|M.abscessus_ATCC_1997 VLLTGIALIRLLGTRAAIPAGLLAGILYGGMAVAVR-VVGGVDP---LSL
: : * *: . . . .:* .: : : .
Mb2748c|M.bovis_AF2122/97 ATLIRTPELYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIASVL
Rv2729c|M.tuberculosis_H37Rv ATLIRTPALYAWILVLPIGLMLQQSSLRVGALTASLPTITVARPVIASVL
MMAR_1984|M.marinum_M GALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLMGAVL
MUL_3372|M.ulcerans_Agy99 GALFRAPEFYVWIAAALGGMIFQQSSFRAGTLTASLPTVVVAKPLMGAVL
Mflv_3964|M.gilvum_PYR-GCK VELLSTPELYAWAVVGILGTSTQQAAFRAGSLTASLPTMTVTEPLVGCAL
Mvan_2432|M.vanbaalenii_PYR-1 TELLRTPELYAWAVVALLGTSTQQAAFRAGALTASLPTMTVAEPVVASVL
MSMEG_2732|M.smegmatis_MC2_155 FTLLRVPELYVWILVAIAGTVVQQSSFRAGALTASLPTMTVTEPVVASVL
MAV_2125|M.avium_104 PALLRTPELYVWVLLAIAATAWEQSAFRAGPLTASLPAVTVAEPIIGSVL
TH_3271|M.thermoresistible__bu AVGVTSPLLYLLILLGVLATLLQQSAFHAGSLQASVPTMLVLEPVVAVAL
MAB_2553|M.abscessus_ATCC_1997 TVLLADPAAYGVVIAGVGGFYLFTVALQIGSVNGAAAALVVGETVVPGVI
. * * . ::: *.: .: .:: * ..:: .:
Mb2748c|M.bovis_AF2122/97 GITVLDEVLHTGRVALVALVAVVVVVVVATVALAR---DEVAMMTVSAGE
Rv2729c|M.tuberculosis_H37Rv GITVLDEVLHTGRVALVALVAAVVVVVVATVALAR---DEVAMMTVSAGE
MMAR_1984|M.marinum_M GMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAVESGH
MUL_3372|M.ulcerans_Agy99 GMVVLGETLDTTGPGLVVVAFGVVLVLVATIALARGEAEKVAEEAVESGH
Mflv_3964|M.gilvum_PYR-GCK GVVVLGETMRPGETGWVLLIAAAVTVVVATAALAR----GEATDLQPATV
Mvan_2432|M.vanbaalenii_PYR-1 SVVVLGETLRPGAAGWATLVVAVAAMVTATAALAR----GEATVKEPSG-
MSMEG_2732|M.smegmatis_MC2_155 GIVVLGETLRPGDAGWVTLVAAIAVMVAATVALAR----GEAAE-EPATV
MAV_2125|M.avium_104 GVTVLGETLRTNGIGLLALGISVAVMAAATVALAR----SQAASAPTADE
TH_3271|M.thermoresistible__bu GAAVLGEHLDINGWEPVPLALAGAAMFAATVALGRN--EGAYEERLEVAA
MAB_2553|M.abscessus_ATCC_1997 GVVLLGDSARPGMGWLVAVAFLGAVVSAVAVAVFG-----AAEHSRPVAP
. .:*.: : . : ..: *:
Mb2748c|M.bovis_AF2122/97 LGAAG-QLAVR---------------------
Rv2729c|M.tuberculosis_H37Rv LGAAG-QLAVR---------------------
MMAR_1984|M.marinum_M IPATMPHRAVTMHFGPADDDVQTDRLRRAPAG
MUL_3372|M.ulcerans_Agy99 IPATMPHRAVTMHFGPADDDVQTDRLRRAPAG
Mflv_3964|M.gilvum_PYR-GCK --------------------------------
Mvan_2432|M.vanbaalenii_PYR-1 --------------------------------
MSMEG_2732|M.smegmatis_MC2_155 PAH-----------------------------
MAV_2125|M.avium_104 IPPFSTEKT-----------------------
TH_3271|M.thermoresistible__bu LAQQSRSQQVRT--------------------
MAB_2553|M.abscessus_ATCC_1997 DPAR----------------------------