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TSHKTFPIAGILFDSDGVLVDSHEAAATAWNHWARTWAPGFDFHRDAQHGRRLSDVVAELVGDGDSALAT KVLTELEIEMATEVPAMAGAVDLLSSSPADRWAVVTSGAREMAAARLLSAGLPTPRVLVSADDVTAGKPA PEPYLTGAHLLGLEPRVCAVFEDAHLGILAARAANVGFVVGVGAQTIGEDVDVSVADLSGITFDGSHLVI EADAVLTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1707 | - | - | 100% (219) | phosphatase YfbT |
| M. smegmatis MC2 155 | MSMEG_4183 | - | 1e-10 | 29.23% (195) | phosphoglycolate phosphatase, chromosomal |
| M. smegmatis MC2 155 | MSMEG_1495 | - | 8e-05 | 27.05% (207) | HAD-superfamily protein hydrolase subfamily protein IA, variant |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3433 | - | 5e-11 | 32.28% (158) | hydrolase |
| M. gilvum PYR-GCK | Mflv_1072 | - | 2e-11 | 32.76% (232) | beta-phosphoglucomutase family hydrolase |
| M. tuberculosis H37Rv | Rv3400 | - | 5e-11 | 32.28% (158) | hydrolase |
| M. leprae Br4923 | MLBr_00393 | - | 4e-10 | 28.96% (221) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2130 | - | 5e-13 | 29.17% (192) | putative hydrolase |
| M. marinum M | MMAR_0580 | - | 3e-22 | 36.36% (176) | hydrolase |
| M. avium 104 | MAV_4350 | - | 1e-10 | 50.72% (69) | beta-phosphoglucomutase hydrolase |
| M. thermoresistible (build 8) | TH_0959 | - | 4e-09 | 37.25% (102) | phosphoglycolate phosphatase, chromosomal |
| M. ulcerans Agy99 | MUL_0545 | - | 2e-22 | 36.36% (176) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_3473 | - | 2e-14 | 28.89% (225) | HAD family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0580|M.marinum_M ------------------MPELHAAALLFDMDGTLVDSTAVVEATWGAFA
MUL_0545|M.ulcerans_Agy99 ------------------MPELHAAALLFDVDGTLVDSTAVVEATWGAFA
Mb3433|M.bovis_AF2122/97 MANWYRPN-YPEVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
Rv3400|M.tuberculosis_H37Rv MANWYRPN-YPEVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
MLBr_00393|M.leprae_Br4923 MANWDHP--TSKVRSTVLGLPEQVRACLFDLDGVLTDTASVHAKAWQTMF
MAV_4350|M.avium_104 MVEWIPPDPNHRKRVPVLGLPEKVHACLFDLDGVLTDTASVHTKAWKAMF
Mflv_1072|M.gilvum_PYR-GCK ------------MKGDMLGLPDRIHACLFDLDGVLTDTASVHRRAWKAMF
MAB_2130|M.abscessus_ATCC_1997 -----------------------MRAVLWDMDGTLIESEKLWDISMGELC
TH_0959|M.thermoresistible__bu ------------------------------MDGTLVDSERLWDLSLRELY
Mvan_3473|M.vanbaalenii_PYR-1 -------MLRGSRRDTAACQNGRVRAVLWDMDGTLVDSEKLWDVSLSALY
MSMEG_1707|M.smegmatis_MC2_155 ---------------MTSHKTFPIAGILFDSDGVLVDSHEAAATAWNHWA
**.* :: :
MMAR_0580|M.marinum_M ELHS-----------------LDLAEVLAFAHGRPTAATVRHFLSHPALV
MUL_0545|M.ulcerans_Agy99 ELHS-----------------LDLAEVLAFAHGRPTAATVRHFLSHPALV
Mb3433|M.bovis_AF2122/97 DAYL---AERAERTGEKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
Rv3400|M.tuberculosis_H37Rv DAYL---AERAERTGEKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
MLBr_00393|M.leprae_Br4923 DTYL---YQRAKHTGENFVPFDPTADYRQYVDGKKREDGVRSFLGSRGIT
MAV_4350|M.avium_104 DAYL---ADRAKRTGETFVPFDPAADYRKYVDGKKREDGVRSFLQSRGIH
Mflv_1072|M.gilvum_PYR-GCK DEYLSDIADGAEDPDARYTPFDAGADYETYVDGKPRADGIRSFLGSRLID
MAB_2130|M.abscessus_ATCC_1997 RKLG----------------GEMTPELRTALVGGAADATMRMIFTALELE
TH_0959|M.thermoresistible__bu RRLG----------------RELRPEVRAATVGGAADTVMRIVYDDLGLD
Mvan_3473|M.vanbaalenii_PYR-1 ETFG----------------GVMSRETRATLVGASAEETMVTVYTELGLD
MSMEG_1707|M.smegmatis_MC2_155 RTWAP-----------------GFDFHRDAQHGRRLSDVVAELVGDGDSA
* : .
MMAR_0580|M.marinum_M ASET-----------------RRLVEHEESTTEGVREVPGAAEFIAALPR
MUL_0545|M.ulcerans_Agy99 ASET-----------------RRLVEHEESTTEGVREVPGAAEFIAALPR
Mb3433|M.bovis_AF2122/97 IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
Rv3400|M.tuberculosis_H37Rv IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
MLBr_00393|M.leprae_Br4923 LPEGSADNSGDVETIYGLGNRKDDLFRQVLKEHGIEVFDGSRRYLEAITY
MAV_4350|M.avium_104 LPDGSPDDAGDAETIYGLGNRKNDMFQKVLKQDGVKVFDGSRRYLEAASA
Mflv_1072|M.gilvum_PYR-GCK VDEA---------TVTRLGDRKNEMFRKTLKSDGIEVFDGSRRYLQAAAD
MAB_2130|M.abscessus_ATCC_1997 PDPV----------RMASENDWLHQYTGELFATGLIWCDGAQEMLGQLAA
TH_0959|M.thermoresistible__bu PDPE----------AMARTADWLHDYTGELFASGLPWCAGARELLDELAA
Mvan_3473|M.vanbaalenii_PYR-1 LDPE----------AMAESVRWLHDHTAELFDGGLPWCDGAREMLEGLAA
MSMEG_1707|M.smegmatis_MC2_155 LATK------------------VLTELEIEMATEVPAMAGAVDLLSSSPA
*: : .
MMAR_0580|M.marinum_M SAWAVVTSASRVLASNRMRAAGIP-----LPDVLISADDITRGKPDPQGY
MUL_0545|M.ulcerans_Agy99 SAWAVVTSASRVLASNRMRAAGIP-----LPDVLISADDITRGKPDPQGY
Mb3433|M.bovis_AF2122/97 AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
Rv3400|M.tuberculosis_H37Rv AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
MLBr_00393|M.leprae_Br4923 AGLGVAVVSSSTNTRDVLKITGLDRFVQQQVDGITLREEHIAGKPAPDSY
MAV_4350|M.avium_104 AGLGIAVVSSSANTRDVLEVTGLDRFVQQRVDGITLREEHLAGKPAPDSF
Mflv_1072|M.gilvum_PYR-GCK AGLRRAVVSSSANTREVLELTGLDRYVEVRVDGVTLREENLPGKPAPDTY
MAB_2130|M.abscessus_ATCC_1997 EQMPMALVTN---TIRSLTDQALKTIGTHWFTESVCGDEVPAGKPAPDPY
TH_0959|M.thermoresistible__bu AAVPMALVTN---TRRTLTEQALHSIGRHYFAVTVCGDEVPNGKPAPDIY
Mvan_3473|M.vanbaalenii_PYR-1 ERTPAALVTN---TQRGLTERALNSIGRHYFSVTVCADEVASGKPAPDPY
MSMEG_1707|M.smegmatis_MC2_155 DRWAVVTSGAREMAAARLLSAGLP-----TPRVLVSADDVTAGKPAPEPY
. : : .: :: *** *: :
MMAR_0580|M.marinum_M LLAADALRVNIGSTIVFEDSPAGIRAGIASNALTVAIGTLAAFDGHIERF
MUL_0545|M.ulcerans_Agy99 LLAADALRVNIGSTIVFEDSPAGIRAGIASNALTVAIGTLAAFDGHIERF
Mb3433|M.bovis_AF2122/97 LRAAELLGVTPDAAAVFEDALSGVAAGRAG-NFAVVVG--------INRT
Rv3400|M.tuberculosis_H37Rv LRAAELLGVTPDAAAVFEDALSGVAAGRAG-NFAVVVG--------INRT
MLBr_00393|M.leprae_Br4923 LRGAQLLDVAPDAAAVFEDALSGVQAGLSG-HFGFVVG--------INRT
MAV_4350|M.avium_104 LRGAQLLDVPAGAAAVFEDALSGVAAGRAG-NFGFVVG--------VDRV
Mflv_1072|M.gilvum_PYR-GCK LRAAELLGVDPAEAAVFEDALSGVAAGRAG-DFGLVVG--------VDRT
MAB_2130|M.abscessus_ATCC_1997 LRAAALLGVEPRDCLAIEDSVTGAAAAEAAGCAVLVVPN----HVEVPAG
TH_0959|M.thermoresistible__bu HRAADLLGVAPEACLAVEDSPTGAAAAEGAGCPVLVVPN----ALEVQHS
Mvan_3473|M.vanbaalenii_PYR-1 LRAAELLGVDPADCLAVEDSVTGTAAAEKAGCAVLVVPN----DVPVPGG
MSMEG_1707|M.smegmatis_MC2_155 LTGAHLLGLEPRVCAVFEDAHLGILAARAANVGFVVGVG--AQTIGEDVD
.* * : ..**: * *. . ..
MMAR_0580|M.marinum_M ENFHGFEVAGQPPAGGVILSMPAPMNCGV----------
MUL_0545|M.ulcerans_Agy99 ENFHGFEVAGQPPAGGVILSMPAPMNCGV----------
Mb3433|M.bovis_AF2122/97 GRAAQAAQLRRHGADVVVTDLAELL--------------
Rv3400|M.tuberculosis_H37Rv GRAAQAAQLRRHGADVVVTDLAELL--------------
MLBr_00393|M.leprae_Br4923 GRVDQAEELRRIGANVVVTDLAELL--------------
MAV_4350|M.avium_104 G---QAEDLRRNGADVVVSDLAELLAS------------
Mflv_1072|M.gilvum_PYR-GCK G---QAQALRDKGADIVITDLGELLT-------------
MAB_2130|M.abscessus_ATCC_1997 ARRRHAASLSGLSVRDLRDAHADVLAATT------CKPI
TH_0959|M.thermoresistible__bu PRRRQIPSLTHVDVPLMREIHADLSAAPGPGVPAGHRPL
Mvan_3473|M.vanbaalenii_PYR-1 LRRRHVGSLAGLDVADLRRIYAEIDRELR------ERTA
MSMEG_1707|M.smegmatis_MC2_155 VSVADLSGITFDGSHLVIEADAVLTR-------------
: