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RCTMSPHMAELDGKVAIVTGTSRGVGVGIAHELLRAGATVIGCSRAPMDALPGTEDDPAWTERSAQMVCD QADYRAIDAFVTRVVDTYGRLDILVNNAGGTVPSPSVDAVPSLVSRIQGAPASDDDYERSVLFHAFAVQM NLISPLWFAIRAYRQMKTQDGTGCIINISSGASHAAGSPTLVSYGAAKAGLNQMTRSLAQEWGPAARVNC LALGPTITENFQSFVLPKDDPDGEKYFDPIPLKRGGQPTEVGRTCVFLASGAADYINGTTIEIDGGMLPG VLYDAGLKTITDLL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0927 | - | - | 100% (295) | short-chain dehydrogenase/reductase SDR |
| M. gilvum PYR-GCK | Mflv_1491 | - | 5e-32 | 37.25% (255) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1776 | - | 3e-30 | 33.70% (276) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3579c | - | 8e-35 | 34.94% (269) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv3549c | - | 8e-35 | 34.94% (269) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-15 | 30.42% (263) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0607 | - | 3e-38 | 37.36% (273) | short chain dehydrogenase |
| M. marinum M | MMAR_5037 | - | 2e-36 | 35.32% (269) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_0354 | - | 1e-132 | 77.70% (287) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_6000 | - | 8e-39 | 37.92% (269) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2432 | - | 7e-36 | 36.80% (269) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_4111 | - | 2e-36 | 35.32% (269) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5265 | - | 1e-34 | 36.80% (269) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0927|M.gilvum_PYR-GCK ---MRCTMSPH----MAELDGKVAIVTGTSRGVGVGIAHELLRAGATVIG
MAV_0354|M.avium_104 ---------------MGVLEGKVAIVTGTSRGVGVGIAHELLRAGATVVG
MSMEG_6000|M.smegmatis_MC2_155 ---MTDMPEAG--AINLGLTGKVVLVTGGVRGVGAGISAVFAGQGATVVT
Mvan_5265|M.vanbaalenii_PYR-1 ---MTDAVDSARRGIALGLTGRVVLVTGGVRGVGAGISKVFADQGATVVT
TH_2432|M.thermoresistible__bu --------------VNLGLTGRVVLVTGGVRGVGAGISAVFADQGATVVT
Mb3579c|M.bovis_AF2122/97 ---MTLAEAAD--AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Rv3549c|M.tuberculosis_H37Rv ---MTLAEAAD--AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
MMAR_5037|M.marinum_M ---MTRAAAAQ--AINLGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
MUL_4111|M.ulcerans_Agy99 ---MTRAEAAQ--AINLGLVGRVVLVTGGVRGVGAGISSVFAEQGATVIT
MAB_0607|M.abscessus_ATCC_1997 ---MRTP-------YDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .: :*** **:* .:: : * *
Mflv_0927|M.gilvum_PYR-GCK CSRAPMDALPGTEDDPAWTERSAQMVCDQADYRAIDAFVTRVVDTYGRLD
MAV_0354|M.avium_104 CARSPLDTIPGIEPD--WAERAFQRVCDQGDYRGIDAFVTDVVATHGRVD
MSMEG_6000|M.smegmatis_MC2_155 CARRPVEGLPYEFHS-----------CDVRDDESVAALITAIVEKHGRID
Mvan_5265|M.vanbaalenii_PYR-1 CARRPVEGSPYEFRS-----------CDIREDDSVKGLVEGIVSDHGRLD
TH_2432|M.thermoresistible__bu CARRPVDGLPYEFHS-----------CDVRDDDAVAAMIDTIVDRHGRLD
Mb3579c|M.bovis_AF2122/97 CARRAVDGQPYEFHR-----------CDIRDEDSVKRLVGEIGERHGRLD
Rv3549c|M.tuberculosis_H37Rv CARRAVDGQPYEFHR-----------CDIRDEDSVKRLVGEIGERHGRLD
MMAR_5037|M.marinum_M CARRAVENSPHEFHC-----------CDIRDEDSVKRLMGSIAERHGRLD
MUL_4111|M.ulcerans_Agy99 CARRAVENSPHEFHC-----------CDIRDEDSVKRLMGSIAERHGRLD
MAB_0607|M.abscessus_ATCC_1997 CARRPGD-APYEFHS-----------CDVRDEESVDTLIGAIVAAHGRLD
MLBr_01807|M.leprae_Br4923 THR--ASVVPDWFFG---------VECDVTDNDAIGAAFKAVEEHQGPVE
* . * ** : .: . : * ::
Mflv_0927|M.gilvum_PYR-GCK ILVNNAGGTVPSPSVDAVPSLVSRIQGAPASDDDYERSVLFHAFAVQMNL
MAV_0354|M.avium_104 ILVNNAGGTVPAPHAETIPELVQRIQGSPAADDDYARTALFHAFAVQMNL
MSMEG_6000|M.smegmatis_MC2_155 VVVNNAGGSPYVPASEASARFSSKI--------------------IELNL
Mvan_5265|M.vanbaalenii_PYR-1 VVVNNAGGSPYVLAADASARFSAKI--------------------VALNL
TH_2432|M.thermoresistible__bu VVVNNAGGSPYVLTAESSAKFNRKI--------------------IELNL
Mb3579c|M.bovis_AF2122/97 MLVNNAGGSPYALAAEATHNFHRKI--------------------VELNV
Rv3549c|M.tuberculosis_H37Rv MLVNNAGGSPYALAAEATHNFHRKI--------------------VELNV
MMAR_5037|M.marinum_M VLVNNAGGSPYALAAEATPRFHSKI--------------------VELNL
MUL_4111|M.ulcerans_Agy99 VLVNNAGGSPYALAAEATPRFHSKI--------------------VELNL
MAB_0607|M.abscessus_ATCC_1997 AVVNNAGGAPFALAADASHNFHRKI--------------------IELNL
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKV--------------------IDVNL
:* *** : :: : :*:
Mflv_0927|M.gilvum_PYR-GCK ISPLWFAIRAYRQMKTQDGTGCIINISSGASHAAGSPTLVSYGAAKAGLN
MAV_0354|M.avium_104 IGPLWFAIRAYRQMQTQDGMGCIINISSGAGHPAGAPTLVSYGAAKSGLN
MSMEG_6000|M.smegmatis_MC2_155 LGPLSVSQHANAVMQNQDTGGVIVNISSVSGRRP-TPGTAAYGAAKAGVD
Mvan_5265|M.vanbaalenii_PYR-1 LGALSVSTHANAAMQAQAAGGSIVNITSVSGRRP-TPGTVAYGAAKAGME
TH_2432|M.thermoresistible__bu LGPLSVSQHANAHMQKQPRGGSIINIASVSGRRP-TPGTAPYGAAKAGVE
Mb3579c|M.bovis_AF2122/97 LAPLLVSQHANVLMQAQPNGGSIVNICSVSGRRP-TPGTAAYGAAKAGLE
Rv3549c|M.tuberculosis_H37Rv LAPLLVSQHANVLMQAQPNGGSIVNICSVSGRRP-TPGTAAYGAAKAGLE
MMAR_5037|M.marinum_M LAPLLVSQHAYGLMQEQPTGGSIVNVCSVSGRRP-TPGTAAYGAAKAGFE
MUL_4111|M.ulcerans_Agy99 LAPLLVSQHAYGLMQEQPTGGSIVNVCSVSGRRP-TPGTAAYGAAKAGFE
MAB_0607|M.abscessus_ATCC_1997 LSALLVSQRANAVMQKQDGGGTIVNITSVSAGRP-SPGTAAYGAAKAGLE
MLBr_01807|M.leprae_Br4923 TGVFRVAKLASRNMIKQR-FGRYIFMGSVVGLSG-VPGQANYAASKSGLI
. : .: * * * * : : * . * . *.*:*:*.
Mflv_0927|M.gilvum_PYR-GCK QMTRSLAQEWGP-AARVNCLALGPTITENFQSFVLPKDDPDGEKYFDPIP
MAV_0354|M.avium_104 HLTRSLAQEWGP-KVRVNCVALGPTMTENFRSFVLPKDDPTGEKYFAAVP
MSMEG_6000|M.smegmatis_MC2_155 NLTETLAVEWAP-KVRVNSVVVGMVETE--QSELFYGDADSIAAISKNVP
Mvan_5265|M.vanbaalenii_PYR-1 NMTATLAVEWAP-KVRVNSVVVGMVETE--QSELFYGDADSIAAISKNVP
TH_2432|M.thermoresistible__bu SLTSTLAVEWAP-KVRVNSVVVGMVETE--QADLFYGDAESIAAISKNVP
Mb3579c|M.bovis_AF2122/97 NLTTTLAVEWAP-KVRVNAVVVGMVETE--RSELFYGDAESIARVAATVP
Rv3549c|M.tuberculosis_H37Rv NLTTTLAVEWAP-KVRVNAVVVGMVETE--RSELFYGDAESIARVAATVP
MMAR_5037|M.marinum_M SLTSTLAVEWAP-KIRVNALVVGMVATE--QSELFYGDAESIARVAATVP
MUL_4111|M.ulcerans_Agy99 SLTSTLAVEWAP-KIRVNALVVGMVATE--QSELFYGDAESIARVAATVP
MAB_0607|M.abscessus_ATCC_1997 SLTRSLAVEWAP-KVRVNALAAGMIRTE--LSEMHYGDEDGIAAVGATVP
MLBr_01807|M.leprae_Br4923 GMARSLARELGSRSITANVVAPGFIDTE----MTRAMDSKYQEAALQAIP
:: :** * .. .* :. * ** * :*
Mflv_0927|M.gilvum_PYR-GCK LKRGGQPTEVGRTCVFLASGAADYINGTTIEIDGGMLPGVLYDAGLKTIT
MAV_0354|M.avium_104 LRRAGEPAEVGRICVFLAGGQADFVNGTTIECDGGMLPGVLYDAGLKTIT
MSMEG_6000|M.smegmatis_MC2_155 LGRLAKPADIGWAAAFLASDAASYISGASLEVHGGGEPPHYLATTTAELK
Mvan_5265|M.vanbaalenii_PYR-1 LGRLAKPEDIGWATAFLASDAASYISGASLEVHGGGEPPHYLATTTADIK
TH_2432|M.thermoresistible__bu LGRLATPADVGWATAFLASDVASYISGASLEVHGGGEPPHYLAATNADAI
Mb3579c|M.bovis_AF2122/97 LGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSANK-
Rv3549c|M.tuberculosis_H37Rv LGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSANK-
MMAR_5037|M.marinum_M LGRLAQPADIGWAAAFLASDLASYISGATLEVHGGGEPPPYLAASSANK-
MUL_4111|M.ulcerans_Agy99 LGRLAQPADIGWAAAFLASDLASYISGATLEVHGGGEPPPYLAASSANK-
MAB_0607|M.abscessus_ATCC_1997 LGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHGGGERPAFLDAANVNSN
MLBr_01807|M.leprae_Br4923 LGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH----------
* * . ::. ***. :.::.*: : .**
Mflv_0927|M.gilvum_PYR-GCK DLL---
MAV_0354|M.avium_104 DLL---
MSMEG_6000|M.smegmatis_MC2_155 ------
Mvan_5265|M.vanbaalenii_PYR-1 TQG---
TH_2432|M.thermoresistible__bu K-----
Mb3579c|M.bovis_AF2122/97 ------
Rv3549c|M.tuberculosis_H37Rv ------
MMAR_5037|M.marinum_M ------
MUL_4111|M.ulcerans_Agy99 ------
MAB_0607|M.abscessus_ATCC_1997 ENGEKE
MLBr_01807|M.leprae_Br4923 ------