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TRAAAAQAINLGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVENSPHEFHCCDIRDEDSVKR LMGSIAERHGRLDVLVNNAGGSPYALAAEATPRFHSKIVELNLLAPLLVSQHAYGLMQEQPTGGSIVNVC SVSGRRPTPGTAAYGAAKAGFESLTSTLAVEWAPKIRVNALVVGMVATEQSELFYGDAESIARVAATVPL GRLAQPADIGWAAAFLASDLASYISGATLEVHGGGEPPPYLAASSANK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5037 | - | - | 100% (259) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_4581 | - | 1e-33 | 36.33% (245) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_1952 | fabG | 4e-33 | 35.06% (251) | short-chain type dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3579c | - | 1e-127 | 87.64% (259) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1491 | - | 8e-97 | 74.89% (231) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv3549c | - | 1e-127 | 87.64% (259) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-23 | 31.87% (251) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0607 | - | 2e-94 | 67.74% (248) | short chain dehydrogenase |
| M. avium 104 | MAV_0611 | - | 1e-104 | 75.52% (241) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6000 | - | 1e-108 | 74.71% (257) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2432 | - | 1e-108 | 74.30% (249) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_4111 | - | 1e-144 | 99.23% (259) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5265 | - | 1e-104 | 73.23% (254) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5037|M.marinum_M -----MTRAAAAQAINLGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
MUL_4111|M.ulcerans_Agy99 -----MTRAEAAQAINLGLVGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Mb3579c|M.bovis_AF2122/97 -----MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Rv3549c|M.tuberculosis_H37Rv -----MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Mflv_1491|M.gilvum_PYR-GCK --------------------------------MGAGISRVFADQGATVIT
Mvan_5265|M.vanbaalenii_PYR-1 ---MTDAVDSARRGIALGLTGRVVLVTGGVRGVGAGISKVFADQGATVVT
MSMEG_6000|M.smegmatis_MC2_155 ---MTDMPEAG--AINLGLTGKVVLVTGGVRGVGAGISAVFAGQGATVVT
MAV_0611|M.avium_104 ----------------------MVLVTGGVRGVGAGISSVFAAQGATVVT
TH_2432|M.thermoresistible__bu --------------VNLGLTGRVVLVTGGVRGVGAGISAVFADQGATVVT
MAB_0607|M.abscessus_ATCC_1997 ----------MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
:* .:: :. :* * .
MMAR_5037|M.marinum_M CARRAVENSPHEFHCCDIRDEDSVKRLMGSIAERHGRLDVLVNNAGGSPY
MUL_4111|M.ulcerans_Agy99 CARRAVENSPHEFHCCDIRDEDSVKRLMGSIAERHGRLDVLVNNAGGSPY
Mb3579c|M.bovis_AF2122/97 CARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPY
Rv3549c|M.tuberculosis_H37Rv CARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPY
Mflv_1491|M.gilvum_PYR-GCK CARRPVEDSPFEFRACDIRDDDAVKALVDGIASDHGRLDVVVNNAGGSPY
Mvan_5265|M.vanbaalenii_PYR-1 CARRPVEGSPYEFRSCDIREDDSVKGLVEGIVSDHGRLDVVVNNAGGSPY
MSMEG_6000|M.smegmatis_MC2_155 CARRPVEGLPYEFHSCDVRDDESVAALITAIVEKHGRIDVVVNNAGGSPY
MAV_0611|M.avium_104 CARRAVEGLPYEFHSCDVRDDDAVKALIDTIADRHGRLDVVVNNAGGSPY
TH_2432|M.thermoresistible__bu CARRPVDGLPYEFHSCDVRDDDAVAAMIDTIVDRHGRLDVVVNNAGGSPY
MAB_0607|M.abscessus_ATCC_1997 CARRPGD-APYEFHSCDVRDEESVDTLIGAIVAAHGRLDAVVNNAGGAPF
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAGITSD
* . . **: ::::: . : :* :: :* *** :.
MMAR_5037|M.marinum_M ALAAEATPRFHSKIVELNLLAPLLVSQHAYGLMQEQPTGGSIVNVCSVSG
MUL_4111|M.ulcerans_Agy99 ALAAEATPRFHSKIVELNLLAPLLVSQHAYGLMQEQPTGGSIVNVCSVSG
Mb3579c|M.bovis_AF2122/97 ALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSG
Rv3549c|M.tuberculosis_H37Rv ALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSG
Mflv_1491|M.gilvum_PYR-GCK VLAAEASAKFSTKIVALNLLGALSVSTHANSVMQKQDTGGSIVNISSVSG
Mvan_5265|M.vanbaalenii_PYR-1 VLAADASARFSAKIVALNLLGALSVSTHANAAMQAQAAGGSIVNITSVSG
MSMEG_6000|M.smegmatis_MC2_155 VPASEASARFSSKIIELNLLGPLSVSQHANAVMQNQDTGGVIVNISSVSG
MAV_0611|M.avium_104 VLTAESSAKFNRKIIELNLIGALSVSQHANAHMQKQAQGGSIVNICSLSG
TH_2432|M.thermoresistible__bu VLTAESSAKFNRKIIELNLLGPLSVSQHANAHMQKQPRGGSIINIASVSG
MAB_0607|M.abscessus_ATCC_1997 ALAADASHNFHRKIIELNLLSALLVSQRANAVMQKQDGGGTIVNITSVSA
MLBr_01807|M.leprae_Br4923 MLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG-RYIFMGSVVG
: . *:: :*: . : *: * * * * : : *: .
MMAR_5037|M.marinum_M RRPTPGTAAYGAAKAGFESLTSTLAVEWAPK-IRVNALVVGMVATEQSEL
MUL_4111|M.ulcerans_Agy99 RRPTPGTAAYGAAKAGFESLTSTLAVEWAPK-IRVNALVVGMVATEQSEL
Mb3579c|M.bovis_AF2122/97 RRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VRVNAVVVGMVETERSEL
Rv3549c|M.tuberculosis_H37Rv RRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VRVNAVVVGMVETERSEL
Mflv_1491|M.gilvum_PYR-GCK HRPTPGTAAYGAAKAGIDNLTSTLAVEWAPK-VRVNSVVVGMVETEQSEL
Mvan_5265|M.vanbaalenii_PYR-1 RRPTPGTVAYGAAKAGMENMTATLAVEWAPK-VRVNSVVVGMVETEQSEL
MSMEG_6000|M.smegmatis_MC2_155 RRPTPGTAAYGAAKAGVDNLTETLAVEWAPK-VRVNSVVVGMVETEQSEL
MAV_0611|M.avium_104 RRPSPGTGAYGAAKAGLESLTQTLAVEWGPK-VRVNACVVGMVETEQSEL
TH_2432|M.thermoresistible__bu RRPTPGTAPYGAAKAGVESLTSTLAVEWAPK-VRVNSVVVGMVETEQADL
MAB_0607|M.abscessus_ATCC_1997 GRPSPGTAAYGAAKAGLESLTRSLAVEWAPK-VRVNALAAGMIRTELSEM
MLBr_01807|M.leprae_Br4923 LSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTRA
** *.*:*:*. .:: :** * ..: : .* . *:: ** :
MMAR_5037|M.marinum_M FYGDAESIARVAATVPLGRLAQPADIGWAAAFLASDLASYISGATLEVHG
MUL_4111|M.ulcerans_Agy99 FYGDAESIARVAATVPLGRLAQPADIGWAAAFLASDLASYISGATLEVHG
Mb3579c|M.bovis_AF2122/97 FYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHG
Rv3549c|M.tuberculosis_H37Rv FYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHG
Mflv_1491|M.gilvum_PYR-GCK FYGDADSIAAISKNVPLGRLAQPEDIGWATAFLASDAASYISGASLEVHG
Mvan_5265|M.vanbaalenii_PYR-1 FYGDADSIAAISKNVPLGRLAKPEDIGWATAFLASDAASYISGASLEVHG
MSMEG_6000|M.smegmatis_MC2_155 FYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAASYISGASLEVHG
MAV_0611|M.avium_104 FYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYISGASLEVHG
TH_2432|M.thermoresistible__bu FYGDAESIAAISKNVPLGRLATPADVGWATAFLASDVASYISGASLEVHG
MAB_0607|M.abscessus_ATCC_1997 HYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHG
MLBr_01807|M.leprae_Br4923 MDS--KYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDG
. . :****:. ::. :.:**** : *::*: : *.*
MMAR_5037|M.marinum_M GGEPPPYLAASSANK-------
MUL_4111|M.ulcerans_Agy99 GGEPPPYLAASSANK-------
Mb3579c|M.bovis_AF2122/97 GGEPPPYLGASSANK-------
Rv3549c|M.tuberculosis_H37Rv GGEPPPYLGASSANK-------
Mflv_1491|M.gilvum_PYR-GCK GGEPPHYLSTTTADIK------
Mvan_5265|M.vanbaalenii_PYR-1 GGEPPHYLATTTADIKTQG---
MSMEG_6000|M.smegmatis_MC2_155 GGEPPHYLATTTAELK------
MAV_0611|M.avium_104 GGEPPHYLATTNASAIK-----
TH_2432|M.thermoresistible__bu GGEPPHYLAATNADAIK-----
MAB_0607|M.abscessus_ATCC_1997 GGERPAFLDAANVNSNENGEKE
MLBr_01807|M.leprae_Br4923 GLGMGH----------------
*