For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TDAVDSARRGIALGLTGRVVLVTGGVRGVGAGISKVFADQGATVVTCARRPVEGSPYEFRSCDIREDDSV KGLVEGIVSDHGRLDVVVNNAGGSPYVLAADASARFSAKIVALNLLGALSVSTHANAAMQAQAAGGSIVN ITSVSGRRPTPGTVAYGAAKAGMENMTATLAVEWAPKVRVNSVVVGMVETEQSELFYGDADSIAAISKNV PLGRLAKPEDIGWATAFLASDAASYISGASLEVHGGGEPPHYLATTTADIKTQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5265 | - | - | 100% (265) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4921 | - | 1e-33 | 35.80% (243) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1212 | - | 2e-32 | 34.58% (240) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3579c | - | 1e-105 | 74.70% (253) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1491 | - | 1e-117 | 88.41% (233) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv3549c | - | 1e-105 | 74.70% (253) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 7e-26 | 31.47% (251) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0607 | - | 2e-91 | 65.48% (252) | short chain dehydrogenase |
| M. marinum M | MMAR_5037 | - | 1e-104 | 73.23% (254) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_0611 | - | 1e-110 | 82.08% (240) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6000 | - | 1e-118 | 81.68% (262) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2432 | - | 1e-115 | 80.72% (249) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_4111 | - | 1e-104 | 73.52% (253) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3579c|M.bovis_AF2122/97 -----MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Rv3549c|M.tuberculosis_H37Rv -----MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
MMAR_5037|M.marinum_M -----MTRAAAAQAINLGLAGRVVLVTGGVRGVGAGISSVFAEQGATVIT
MUL_4111|M.ulcerans_Agy99 -----MTRAEAAQAINLGLVGRVVLVTGGVRGVGAGISSVFAEQGATVIT
Mvan_5265|M.vanbaalenii_PYR-1 ---MTDAVDSARRGIALGLTGRVVLVTGGVRGVGAGISKVFADQGATVVT
Mflv_1491|M.gilvum_PYR-GCK --------------------------------MGAGISRVFADQGATVIT
MSMEG_6000|M.smegmatis_MC2_155 ---MTDMPEAG--AINLGLTGKVVLVTGGVRGVGAGISAVFAGQGATVVT
MAV_0611|M.avium_104 ----------------------MVLVTGGVRGVGAGISSVFAAQGATVVT
TH_2432|M.thermoresistible__bu --------------VNLGLTGRVVLVTGGVRGVGAGISAVFADQGATVVT
MAB_0607|M.abscessus_ATCC_1997 ----------MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
:* .:: :. :* * .
Mb3579c|M.bovis_AF2122/97 CARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPY
Rv3549c|M.tuberculosis_H37Rv CARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPY
MMAR_5037|M.marinum_M CARRAVENSPHEFHCCDIRDEDSVKRLMGSIAERHGRLDVLVNNAGGSPY
MUL_4111|M.ulcerans_Agy99 CARRAVENSPHEFHCCDIRDEDSVKRLMGSIAERHGRLDVLVNNAGGSPY
Mvan_5265|M.vanbaalenii_PYR-1 CARRPVEGSPYEFRSCDIREDDSVKGLVEGIVSDHGRLDVVVNNAGGSPY
Mflv_1491|M.gilvum_PYR-GCK CARRPVEDSPFEFRACDIRDDDAVKALVDGIASDHGRLDVVVNNAGGSPY
MSMEG_6000|M.smegmatis_MC2_155 CARRPVEGLPYEFHSCDVRDDESVAALITAIVEKHGRIDVVVNNAGGSPY
MAV_0611|M.avium_104 CARRAVEGLPYEFHSCDVRDDDAVKALIDTIADRHGRLDVVVNNAGGSPY
TH_2432|M.thermoresistible__bu CARRPVDGLPYEFHSCDVRDDDAVAAMIDTIVDRHGRLDVVVNNAGGSPY
MAB_0607|M.abscessus_ATCC_1997 CARRPGD-APYEFHSCDVRDEESVDTLIGAIVAAHGRLDAVVNNAGGAPF
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAGITSD
* . . **: ::::: . : :* :: :* *** :.
Mb3579c|M.bovis_AF2122/97 ALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSG
Rv3549c|M.tuberculosis_H37Rv ALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSG
MMAR_5037|M.marinum_M ALAAEATPRFHSKIVELNLLAPLLVSQHAYGLMQEQPTGGSIVNVCSVSG
MUL_4111|M.ulcerans_Agy99 ALAAEATPRFHSKIVELNLLAPLLVSQHAYGLMQEQPTGGSIVNVCSVSG
Mvan_5265|M.vanbaalenii_PYR-1 VLAADASARFSAKIVALNLLGALSVSTHANAAMQAQAAGGSIVNITSVSG
Mflv_1491|M.gilvum_PYR-GCK VLAAEASAKFSTKIVALNLLGALSVSTHANSVMQKQDTGGSIVNISSVSG
MSMEG_6000|M.smegmatis_MC2_155 VPASEASARFSSKIIELNLLGPLSVSQHANAVMQNQDTGGVIVNISSVSG
MAV_0611|M.avium_104 VLTAESSAKFNRKIIELNLIGALSVSQHANAHMQKQAQGGSIVNICSLSG
TH_2432|M.thermoresistible__bu VLTAESSAKFNRKIIELNLLGPLSVSQHANAHMQKQPRGGSIINIASVSG
MAB_0607|M.abscessus_ATCC_1997 ALAADASHNFHRKIIELNLLSALLVSQRANAVMQKQDGGGTIVNITSVSA
MLBr_01807|M.leprae_Br4923 MLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG-RYIFMGSVVG
: . *:: :*: . : *: * * * * : : *: .
Mb3579c|M.bovis_AF2122/97 RRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VRVNAVVVGMVETERSEL
Rv3549c|M.tuberculosis_H37Rv RRPTPGTAAYGAAKAGLENLTTTLAVEWAPK-VRVNAVVVGMVETERSEL
MMAR_5037|M.marinum_M RRPTPGTAAYGAAKAGFESLTSTLAVEWAPK-IRVNALVVGMVATEQSEL
MUL_4111|M.ulcerans_Agy99 RRPTPGTAAYGAAKAGFESLTSTLAVEWAPK-IRVNALVVGMVATEQSEL
Mvan_5265|M.vanbaalenii_PYR-1 RRPTPGTVAYGAAKAGMENMTATLAVEWAPK-VRVNSVVVGMVETEQSEL
Mflv_1491|M.gilvum_PYR-GCK HRPTPGTAAYGAAKAGIDNLTSTLAVEWAPK-VRVNSVVVGMVETEQSEL
MSMEG_6000|M.smegmatis_MC2_155 RRPTPGTAAYGAAKAGVDNLTETLAVEWAPK-VRVNSVVVGMVETEQSEL
MAV_0611|M.avium_104 RRPSPGTGAYGAAKAGLESLTQTLAVEWGPK-VRVNACVVGMVETEQSEL
TH_2432|M.thermoresistible__bu RRPTPGTAPYGAAKAGVESLTSTLAVEWAPK-VRVNSVVVGMVETEQADL
MAB_0607|M.abscessus_ATCC_1997 GRPSPGTAAYGAAKAGLESLTRSLAVEWAPK-VRVNALAAGMIRTELSEM
MLBr_01807|M.leprae_Br4923 LSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTRA
** *.*:*:*. .:: :** * ..: : .* . *:: ** :
Mb3579c|M.bovis_AF2122/97 FYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHG
Rv3549c|M.tuberculosis_H37Rv FYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHG
MMAR_5037|M.marinum_M FYGDAESIARVAATVPLGRLAQPADIGWAAAFLASDLASYISGATLEVHG
MUL_4111|M.ulcerans_Agy99 FYGDAESIARVAATVPLGRLAQPADIGWAAAFLASDLASYISGATLEVHG
Mvan_5265|M.vanbaalenii_PYR-1 FYGDADSIAAISKNVPLGRLAKPEDIGWATAFLASDAASYISGASLEVHG
Mflv_1491|M.gilvum_PYR-GCK FYGDADSIAAISKNVPLGRLAQPEDIGWATAFLASDAASYISGASLEVHG
MSMEG_6000|M.smegmatis_MC2_155 FYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAASYISGASLEVHG
MAV_0611|M.avium_104 FYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYISGASLEVHG
TH_2432|M.thermoresistible__bu FYGDAESIAAISKNVPLGRLATPADVGWATAFLASDVASYISGASLEVHG
MAB_0607|M.abscessus_ATCC_1997 HYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHG
MLBr_01807|M.leprae_Br4923 MDS--KYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDG
. . :****:. ::. :.:**** : *::*: : *.*
Mb3579c|M.bovis_AF2122/97 GGEPPPYLGASSANK-------
Rv3549c|M.tuberculosis_H37Rv GGEPPPYLGASSANK-------
MMAR_5037|M.marinum_M GGEPPPYLAASSANK-------
MUL_4111|M.ulcerans_Agy99 GGEPPPYLAASSANK-------
Mvan_5265|M.vanbaalenii_PYR-1 GGEPPHYLATTTADIKTQG---
Mflv_1491|M.gilvum_PYR-GCK GGEPPHYLSTTTADIK------
MSMEG_6000|M.smegmatis_MC2_155 GGEPPHYLATTTAELK------
MAV_0611|M.avium_104 GGEPPHYLATTNASAIK-----
TH_2432|M.thermoresistible__bu GGEPPHYLAATNADAIK-----
MAB_0607|M.abscessus_ATCC_1997 GGERPAFLDAANVNSNENGEKE
MLBr_01807|M.leprae_Br4923 GLGMGH----------------
*