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MTMDHHPGTPPERAKGYRALVVDDELPLAEVVASYLEREQFEAVVADNGVDAIAVARDLDPDVVILDIGL PGIDGLEVCRQLRTFSDAYVVMLTARDTEIDTVLGLTVGADDYITKPFSPRELVARIRAMLRRPRVLQSA TATAGIDVAPPRRFGALSIDVAAREVRIDDEQILLTRTEFDILEALSGRPGNVLSRRQLLEIVRDGPWVG NEHLVDVHIGHLRRKLGDDAASPRYIATVRGVGYRMGSGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0893 | - | - | 100% (251) | two component transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2838 | - | e-130 | 92.03% (251) | two component transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3887 | - | e-120 | 85.20% (250) | two component transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0501 | regX3 | 7e-47 | 44.05% (227) | two component sensory transduction protein RegX3 |
| M. tuberculosis H37Rv | Rv0491 | regX3 | 7e-47 | 44.05% (227) | two component sensory transduction protein RegX3 |
| M. leprae Br4923 | MLBr_00773 | mtrA | 1e-45 | 44.35% (230) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3339 | - | 4e-91 | 68.24% (233) | putative sensory transduction protein |
| M. marinum M | MMAR_0816 | regX3 | 1e-46 | 44.05% (227) | two-component sensory transduction protein RegX3 |
| M. avium 104 | MAV_4660 | - | 8e-47 | 44.05% (227) | DNA-binding response regulator |
| M. smegmatis MC2 155 | MSMEG_0937 | regX3 | 7e-49 | 45.81% (227) | DNA-binding response regulator RegX3 |
| M. thermoresistible (build 8) | TH_4312 | - | 7e-47 | 43.61% (227) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 7e-47 | 44.05% (227) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_1834 | - | 1e-116 | 84.21% (247) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0501|M.bovis_AF2122/97 -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
Rv0491|M.tuberculosis_H37Rv -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MAV_4660|M.avium_104 -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MMAR_0816|M.marinum_M -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MUL_4560|M.ulcerans_Agy99 -----------------MTSVLIVEDEESLADPLAFLLRKEGFEATVVTD
MSMEG_0937|M.smegmatis_MC2_155 --------------------MLIVEDEESLADPLAFLLRKEGFEATVVGD
TH_4312|M.thermoresistible__bu -----------------MTSVLIVEDEESLADPLAFLLRKEGFETTIVTD
MLBr_00773|M.leprae_Br4923 ---MD----------IMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGD
Mflv_0893|M.gilvum_PYR-GCK MMTMD-HHPGTPPERAKGYRALVVDDELPLAEVVASYLEREQFEAVVADN
Mvan_1834|M.vanbaalenii_PYR-1 ---ME-REKAAPGGRAAGYRALVVDDEVPLAEVIAGYLEREQFETIVAAN
MAB_3339|M.abscessus_ATCC_1997 ---MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHD
*:*:*: .**: :: *. * *:. : :
Mb0501|M.bovis_AF2122/97 GPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
Rv0491|M.tuberculosis_H37Rv GPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MAV_4660|M.avium_104 GSAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MMAR_0816|M.marinum_M GPAALAEFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MUL_4560|M.ulcerans_Agy99 GPAALAEFDRSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
MSMEG_0937|M.smegmatis_MC2_155 GPSALAEFERSGADIVLLDLMLPGMSGTDVCKQLRARSSVPVIMVTARDS
TH_4312|M.thermoresistible__bu GPSALAEFERSGADIILLDLMLPGMSGTDVCRRLRAKSKVPVIMVTARDS
MLBr_00773|M.leprae_Br4923 GTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTD
Mflv_0893|M.gilvum_PYR-GCK GVDAIAVARDLDPDVVILDIGLPGIDGLEVCRQLRTFSDAYVVMLTARDT
Mvan_1834|M.vanbaalenii_PYR-1 GLDAISVARELDPDVVILDLGLPGIDGLEVCRQIRTFSDAYVVMLTARDT
MAB_3339|M.abscessus_ATCC_1997 GRRALDLAREVDPDVVILDIGLPGVDGIEVCRQLRVFSDAYVVMLTARDT
* *: .*:::**: ***:.* :**: :*. * . ::*:**:
Mb0501|M.bovis_AF2122/97 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEMSDGVLE
Rv0491|M.tuberculosis_H37Rv EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEMSDGVLE
MAV_4660|M.avium_104 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEISDGVLE
MMAR_0816|M.marinum_M EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEVSDGVLE
MUL_4560|M.ulcerans_Agy99 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGD-DDSEVSDGVLE
MSMEG_0937|M.smegmatis_MC2_155 EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGADNDDAGADDGVLE
TH_4312|M.thermoresistible__bu EIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDLDGADVDDSVLE
MLBr_00773|M.leprae_Br4923 TVDVVLGLESGADDYIMKPFKPKELVARVRARLRRNDD-----EPAEMLS
Mflv_0893|M.gilvum_PYR-GCK EIDTVLGLTVGADDYITKPFSPRELVARIRAMLRRPRVLQSATATAGIDV
Mvan_1834|M.vanbaalenii_PYR-1 EIDTVLGLTVGADDYVTKPFSPRELVARIRAMLRRPRVLHTAGAAAERNV
MAB_3339|M.abscessus_ATCC_1997 EVDTIVGLSVGADDYVTKPFSPREVVARVRAMLRRPRRAPESPAAVTPEL
:* ::** *****: **:..:*::**:** ***
Mb0501|M.bovis_AF2122/97 S-----GPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQ
Rv0491|M.tuberculosis_H37Rv S-----GPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQ
MAV_4660|M.avium_104 S-----GPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQ
MMAR_0816|M.marinum_M S-----GPVRMDVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRGQ
MUL_4560|M.ulcerans_Agy99 S-----GPVRMDVERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRGQ
MSMEG_0937|M.smegmatis_MC2_155 A-----GPVRMDVERHVVSVNGEPITLPLKEFDLLEYLMRNSGRVLTRGQ
TH_4312|M.thermoresistible__bu A-----GPVRMDVDRHVVTVRGEPITLPLKEFELLEYLLRNSGRVLTRGQ
MLBr_00773|M.leprae_Br4923 I-----ADVDIDVPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDV
Mflv_0893|M.gilvum_PYR-GCK APPRRFGALSIDVAAREVRIDDEQILLTRTEFDILEALSGRPGNVLSRRQ
Mvan_1834|M.vanbaalenii_PYR-1 TPPRQFGPLSIDVAAREVRIDGEPILLTRTEFDILEALSGHPGIVLSRRQ
MAB_3339|M.abscessus_ATCC_1997 SPPRVFGALRINVDGREVHVGERPVTLTRTEFDVLAALSSRPGIVLSRKQ
. : ::* : * : *. **::* * .. *::*
Mb0501|M.bovis_AF2122/97 LIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
Rv0491|M.tuberculosis_H37Rv LIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
MAV_4660|M.avium_104 LIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
MMAR_0816|M.marinum_M LIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
MUL_4560|M.ulcerans_Agy99 LIDRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG
MSMEG_0937|M.smegmatis_MC2_155 LIDRVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG
TH_4312|M.thermoresistible__bu LIDRVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG
MLBr_00773|M.leprae_Br4923 LLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP
Mflv_0893|M.gilvum_PYR-GCK LLEIVRDGPWVGNEHLVDVHIGHLRRKLGDDAASPRYIATVRGVGYRMGS
Mvan_1834|M.vanbaalenii_PYR-1 LIEIVRDGPWVGNEHLVDVHIGHLRRKLGDDAAQPRYIRTVRGVGYRMGT
MAB_3339|M.abscessus_ATCC_1997 LLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTVRGVGYRMGT
*:: * . .: . ::**: :** *: .. .* : ****:**:
Mb0501|M.bovis_AF2122/97 -----
Rv0491|M.tuberculosis_H37Rv -----
MAV_4660|M.avium_104 -----
MMAR_0816|M.marinum_M -----
MUL_4560|M.ulcerans_Agy99 -----
MSMEG_0937|M.smegmatis_MC2_155 -----
TH_4312|M.thermoresistible__bu -----
MLBr_00773|M.leprae_Br4923 P----
Mflv_0893|M.gilvum_PYR-GCK GQ---
Mvan_1834|M.vanbaalenii_PYR-1 GSGAD
MAB_3339|M.abscessus_ATCC_1997 GS---