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PKKYGVKEKDLVVTHVVNMVLTGRLRSGDRLDRNEIASELGLSRVPVQEAVVQLEHDGILSTRYHRGAFV ERFDESTVREHHELYGVLCGLASGRAATASEPTVLADLEAATAQMRSGRDSRQFDSHARRFRSIINGEYA GPRLQAAIDASQTLIPHAFWQSYLQHRDQLLPFYESELTAIRDRDPDAARAACAQRSDVMACALLTELVR RGVLRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0859 | - | - | 100% (217) | regulatory protein GntR, HTH |
| M. gilvum PYR-GCK | Mflv_4366 | - | 5e-11 | 25.47% (212) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4358 | - | 2e-05 | 33.57% (143) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0044c | - | 6e-73 | 60.93% (215) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0043c | - | 6e-73 | 60.93% (215) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1705c | - | 5e-08 | 26.32% (133) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0062 | - | 6e-74 | 63.08% (214) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0060 | - | 5e-75 | 63.55% (214) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_6908 | - | 8e-72 | 58.41% (214) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_0516 | - | 5e-75 | 63.72% (215) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_0061 | - | 2e-73 | 63.08% (214) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_6046 | - | 4e-94 | 77.31% (216) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0044c|M.bovis_AF2122/97 ---MPKKYGVKE----KDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGV
Rv0043c|M.tuberculosis_H37Rv ---MPKKYGVKE----KDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGV
MMAR_0062|M.marinum_M ---MPKKYGVKE----KDQVVAHLLNLILTGKLRSGDRVDRNEIAGSLGV
MUL_0061|M.ulcerans_Agy99 ---MPKKCGVKE----KDQVVAHLLNLILTGKLRSGDRVDRNEIAGGLGV
MAV_0060|M.avium_104 ---MPKKYGVKE----KDLVVSHILHLLLTGKLRTGDRVDRNEIAVGLGV
MSMEG_6908|M.smegmatis_MC2_155 ---MPKKYGVKE----KDQVVSHIINLMMTGKLRTGDRIDRNEIVRDLGL
Mflv_0859|M.gilvum_PYR-GCK ---MPKKYGVKE----KDLVVTHVVNMVLTGRLRSGDRLDRNEIASELGL
Mvan_6046|M.vanbaalenii_PYR-1 ---MPKKYGVKE----KDLVVSHVVEMVLTGRLRSGDRLDRNEIAHDLGL
TH_0516|M.thermoresistible__bu VAAMPKKYGVKE----KDLVVSHVVNLVLTGKLRSGDRLDRNEIARELGL
MAB_1705c|M.abscessus_ATCC_199 -MPVPPSEGIAARSLLRDNAYKALRTAIVDGTLAPGERLRDDELSRWLGV
:* . *: :* . : :: * * .*:*: :*: **:
Mb0044c|M.bovis_AF2122/97 SRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIA
Rv0043c|M.tuberculosis_H37Rv SRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIA
MMAR_0062|M.marinum_M SRVPIQEALVQLEHDGIVSTRYHRGAFVERFDQSTVLEHYELEGVLNGMA
MUL_0061|M.ulcerans_Agy99 SRVPIQEALVQLEHDGVVSTRYHRGAFVERFDQSTVLEHYELEGVLNGMA
MAV_0060|M.avium_104 SRVPIQEALVQLEHDGIVSTRYHRGAFVERFDEATVLEHHELDGLLNGIA
MSMEG_6908|M.smegmatis_MC2_155 SRVPIQEAVVQLEHDGILSTRYHRGAFVARFDEATVAEHHELYGILNGIS
Mflv_0859|M.gilvum_PYR-GCK SRVPVQEAVVQLEHDGILSTRYHRGAFVERFDESTVREHHELYGVLCGLA
Mvan_6046|M.vanbaalenii_PYR-1 SRVPVQEAVVQLEHDGIVSTRYHRGAYVERFDESTVREHHELYGLLSGIA
TH_0516|M.thermoresistible__bu SRVPIQEAVVQLEHDGLLSTRYHRGAYIERFDESVILEHHEVYGVLNGMA
MAB_1705c|M.abscessus_ATCC_199 SRTPIREALARLEQAGLVQTQPGRHTIVSPIDVREARAAQSVAAAMHELA
**.*::**:.:**: *::.*: * : : :* .: . : ::
Mb0044c|M.bovis_AF2122/97 SARAAANPTPRILGQLDAVMRSLRNSKESRA---FAECVWEYRRTVNDEY
Rv0043c|M.tuberculosis_H37Rv SARAAANPTPRILGQLDAVMRSLRNSKESRA---FAECVWEYRRTVNDEY
MMAR_0062|M.marinum_M SARTAANPTPRILGELDGLMRTLRAAKDARI---FAELTSEYRRTINEEY
MUL_0061|M.ulcerans_Agy99 SARTAANPTPRILGELDGLMRTLRAAKDARI---FAELASEYRRTINEEY
MAV_0060|M.avium_104 SARAATSPTPRILGELDTLLRSLRTAKDSRA---FTDIAAQYRRTVNDEY
MSMEG_6908|M.smegmatis_MC2_155 SARCAANPTPRILAQLEESLRIMHAAKDVKT---FQDNCWVFRNTINDEY
Mflv_0859|M.gilvum_PYR-GCK SGRAATASEPTVLADLEAATAQMRSGRDSRQ---FDSHARRFRSIINGEY
Mvan_6046|M.vanbaalenii_PYR-1 SARAAAASDPAVVDTLDGELTQMRGARDSRQ---FDNHADRFRTTINEQY
TH_0516|M.thermoresistible__bu SARAAADPSRRIVDRLEAVARIMANSRGTRK---FLDAAGQYRQLINDEY
MAB_1705c|M.abscessus_ATCC_199 VREAITNISPGDLAAMRHANTRFAAALDAHDPDAALAADDEFHAVAVEAS
. : : : : . : ::
Mb0044c|M.bovis_AF2122/97 AGPRLHATIRASQNLIPRVFWMTYQNSRD-DVLPFYEEENAAIHRREPEA
Rv0043c|M.tuberculosis_H37Rv AGPRLHATIRASQNLIPRVFWMTYQNSRD-DVLPFYEEENAAIHRREPEA
MMAR_0062|M.marinum_M AGPRLQALIRASQNLIPGAFWASYQYRRE-DMLPFYEDEHSAIHRRDPQA
MUL_0061|M.ulcerans_Agy99 AGPRLQALIRASQNLIPGAFWASYQYRRE-DMLPFYEDEHSAIHRRDPQA
MAV_0060|M.avium_104 AGPRLHATIRASQNLIPRLFWTTYQGGRD-DLLPFYEDETSAIHRRDPEA
MSMEG_6908|M.smegmatis_MC2_155 AGPRLQATIRAGESFAPSDFWTGYTPSKT-EFLPTYDDEFAAIRDRDPEN
Mflv_0859|M.gilvum_PYR-GCK AGPRLQAAIDASQTLIPHAFWQSYLQHRD-QLLPFYESELTAIRDRDPDA
Mvan_6046|M.vanbaalenii_PYR-1 AGPRLQAAVNSSRTFIPRAFWQTYPQHRD-RLLPSYEAELAAVRAGEPDA
TH_0516|M.thermoresistible__bu AGPRLRAAIRAAQTFLPRKFWLTCLQDHD-EIWQTYDAETTAIRTGDPEG
MAB_1705c|M.abscessus_ATCC_199 ANPYIAAVLEQVTPVLRRLERIRFASRDGRHSVALHEQIIARCEAGDSEG
*.* : * : . :: : . :.:
Mb0044c|M.bovis_AF2122/97 ARAACIGRSELMAQTMLAELFRRRVLVPPEGACPG---PFGAPIPGFARS
Rv0043c|M.tuberculosis_H37Rv ARAACIGRSELMAQTMLAELFRRRVLVPPEGACPG---PFGAPIPGFARS
MMAR_0062|M.marinum_M ARAACSGRSELMAQSMLAELFRRQVFTPHEQACRHNGHATAAPVAPLPAR
MUL_0061|M.ulcerans_Agy99 ARAACSGRSELMAQAMLAELFRRQVFTPHEQACRNNGHATAAPVAPLPSR
MAV_0060|M.avium_104 ARAACVERSYRMAQTMLGELFRRRVFTPPDDAGRV----VAGPLPVLADA
MSMEG_6908|M.smegmatis_MC2_155 ARKACMHRSEIMSRIMIAELTRRGVFGELRSP------------------
Mflv_0859|M.gilvum_PYR-GCK ARAACAQRSDVMACALLTELVRRGVLRR----------------------
Mvan_6046|M.vanbaalenii_PYR-1 ARAACAQRAEVMASILLTELVRRGVLRAPQSQ------------------
TH_0516|M.thermoresistible__bu ARSACARRSATMGRLMCNELVRRGVLEPTGTVAPTR--------------
MAB_1705c|M.abscessus_ATCC_199 AGRAARDNWHTLIAAPEGAAHEERGAG-----------------------
* *. . : ..
Mb0044c|M.bovis_AF2122/97 YQPSSPVP-------
Rv0043c|M.tuberculosis_H37Rv YQPSSPVP-------
MMAR_0062|M.marinum_M PKIVVETPEATRLAF
MUL_0061|M.ulcerans_Agy99 PKIVVETPEATRLAF
MAV_0060|M.avium_104 DTICGGASLAL----
MSMEG_6908|M.smegmatis_MC2_155 ---------------
Mflv_0859|M.gilvum_PYR-GCK ---------------
Mvan_6046|M.vanbaalenii_PYR-1 ---------------
TH_0516|M.thermoresistible__bu ---------------
MAB_1705c|M.abscessus_ATCC_199 ---------------